CURRICULUM VITAE
Alireza GHOLAMI
Date of birth: 22/12/1967
Place of birth: Khorramshahr, IRAN
Sex: Masculine
Marital status: Married, two children
Address: Pasteur Institute of Iran, WHO-CC for Reference
and Research on Rabies
69, Farvardin st., Pasteur ave., Tehran 13164, Iran
Tel
: +98 21 66403496
Fax
: +98 21 66480777, +98 21 66465132
Cell
: +98 937 19 18 415, +98 912 348 60 80
E-mail: agholami@pasteur.ac.ir, a4gholami@yahoo.co.uk
Educations:
Mars1st- April 2nd 2010, Vaccinology course
Institut Pasteur, Paris (University diploma from Paris Diderot, Paris 7)
October 2005- Nov 2008, PhD in Biochemistry
University of Paris 7, DyLAH unit of the Institut Pasteur, Paris, France
"Characterization of protein domains of lyssavirus matrix protein involved
in the induction of apoptosis"
April 7th- June 25th 2008, Systematic Virology course
Institut Pasteur, Paris (Paris-7 university diploma)
Mars 1st – May 28th, 2005, Pre-thesis research
Rabies Laboratory, DyLAH unit, Institut Pasteur, Paris
“Characterization of proteins domains of the matrix protein of Mokola virus
involved in mitochondrial targeting and induction of apoptosis”
July 2001- Oct 2002, Course of "Protein analysis and characterization"
Centre of Genetic engineering and Biotechnology (CIGB), Havana, Cuba.
September 1991 - February 1995,
MSc in Medical Biochemistry, Sh. Beheshti University of medical sciences,
Tehran, Iran
September 1985 - February 1990,
BSc in Genetics, Jundi-Shapour university, Ahwaz, Iran.
Alireza GHOLAMI-2013
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Professional Experience:
September 2011 – present, Institut Pasteur of Iran (IPI), Production &
Research Complex
Head of rabies vaccine production unit, Department of the viral vaccines
production
2009 – 2010, IPI, Production & Research Complex
Head of the Human rabies vaccine working group
1997– 2009, IPI
Researcher, WHO collaborating centre for reference and research on
Rabies
Publications (selected):
Pagliusi S, Makhoana M, Datla M, Leite L, Hendriks J, Gholami A, Huang W, Gao
Y, Jadhav S, Harshavardhan GV, Wu Y, Suhardono M, Homma A., Developing
Countries Vaccine Manufacturers Network (DCVMN): Engaging to step up for
vaccine discovery and access. Meeting Report 2012, Vaccine, 2013 May 15.
Borhani K, Bamdad T, Ajorloo M, Mozhgani SH, Miandehi N, Moradi-Joshaghan A,
and Gholami A, Cloning and expression of rabies virus glycoprotein gene into
eukaryotic system, Iranian Journal of Virology, summer 2013
Florence Larrous, Alireza Gholami, et al., Two overlapping domains of lyssavirus
matrix protein acting on different cell death pathways, J Virol, 2010
Oct;84(19):9897-906
Zandi F., Vaziri B., Eslami N., Soheili M., Gholami A., and Fayaz A., Proteomics
analysis of BHK-21 cells infected with a fixed strain of rabies virus, Proteomics,
May 2009, Vol.9, No 9.
Stephen C. Graham, René Assenberg, Olivier Delmas, Anil Verma, Alireza
Gholami, Chiraz Talbi, Raymond J. Owens, David I. Stuart, Jonathan M. Grimes
and Hervé Bourhy, Rhabdovirus matrix protein structures reveal a novel mode of
self-association, PLoS Pathogens 2008, Vol. 4, No 12.
Gholami A, Kassis R., Real E., Guadagnini S., Larrous F., Obach D., Prevost
MC., Jacob Y. and Bourhy H., Mitochondrial dysfunction in lyssavirus-induced
apoptosis., J Virol, Mai 2008 Vol 82, No 10.
Simani S, Amirkhani A, Farahtaj F, Hooshmand B, Nadim A, Sharifian J, Howaizi
N, Eslami N, Gholami A, Janani A, Fayaz A., Evaluation of the effectiveness of
pre-exposure rabies vaccination in Iran, Arch Iranian Med., 2004
Simani S, Gholami A, Farahtaj F, Yousefi M, Fayaz A., Epidemiological Survey of
different rabies virus strains in Iran, J Sci I R Iran, 2001
Alireza GHOLAMI-2013
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Projects and Grants:
 Establishment of rabies virus collection using national isolates (running)
 Production of rabies vaccine for human use, by means of alternative purification
methods; grant from Iranian M.O.H (running)
 Study of a new antibiotic combination for elimination of Mycoplasma from
mammalian cell cultures (running)
 Study of efficiency and admissibility of oral vaccination against rabies in wild
Canidae in Iran; grant from Iranian Organization for Protection of the Environment,
(running)
 Improving of thermostability of adjuvanted vaccines by spray drying methods, using
Alum containing rabies vaccine as a model (running)
 Preparation of a rabies antiserum for its use in in vitro techniques (article published)
 Establishing a rabies minigenome in order to obtain reverse genetic system for
rabies rescue viruses (running)
 Improvement of veterinary rabies vaccine production in bioreactors from pilot to
industrial scale (completed)
 Comparative analysis of BHK cells infected by a laboratory strain “Pasteur Virus”
and a wild type “street” rabies virus, using Proteomics techniques (article published)
Languages:
English
French
Persian
Alireza GHOLAMI-2013
: Speaking, Writing
: Speaking, Writing
: Mother tongue
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