Joint OIE/WHO/EU Conference on rabies: Towards the Elimination of rabies in Eurasia 27-30 May 2007, Paris, France Programme Sunday, 27 May 2007 OIE Headquarters, Salle Vittoz 16h00 Registration 18h00 Opening Ceremony Chairperson: G. Brückner (OIE, France) Welcome: Speech of the representatives of the three co-organising bodies B. Vallat (OIE) F.-X. Meslin (WHO) J.-P. Vermeersch (EU) Keynote address J. Blancou Towards the elimination of rabies in Eurasia: Overview and perspectives 19h00 OIE Welcome cocktail Monday, 28 May 2007 OIE Headquarters, Salle Vittoz 09h00 - Session 1 / Epidemiological information. Rabies in Eurasia: Regional reports Chairperson: V. Caporale (IZS, Italy) - Rapporteur: B. Dodet (IABs, Switzerland) 09h00 Rabies situation in Western Europe A.I. Wandeler (CFIA/ACIA, Canada) 09h12 Rabies situation in Eastern Europe O. Matouch (NRLR, Czech Rep.) 09h24 Rabies situation in Central Asia K.N.Gruzdev (FGI-ARRIAH, Russia) 1/7 Joint OIE/WHO/EU Conference on rabies, 27-30 May 2007 - Programme 09h36 Rabies situation in the Middle East A. Seimenis (WHO) 09h48 Rabies situation in Far East Asia Z.F. Fu (UG, USA) 10h00 Discussion 10h30 Coffee break 11h00 - Session 2 / Rabies pathogenesis Chairperson: A.C. Jackson (KGH, Canada) - Rapporteur: M. Lafon (IP, France) 11h00 Cytokine expression in the CNS and periphery N. Johnson (VLA, UK) during infection with rabies 11h10 Neuroimaging, virus and cytokine studies in T. Hemachudha (CU, Thailand) rabies infected dogs 11h20 Role of Calcitonin Gene-Related Peptide (CGRP) E. Weihe (UM, Germany) in the pathogenesis of rabies 11h30 Pathogenic and attenuated rabies viruses Z.F. Fu (UG, USA) induces differential host protein expression in the central nervous system: Implication of neuronal dysfunction 11h40 Dominance of a non-pathogenic over a pathogenic B. Dietzschold (TJU, USA) G protein gene in defining the pathogenicity of a rabies virus 11h50 Discussion 12h00 Lunch break 13h30 - Session 3 / Rabies prevention and control strategies 13h30 Keynote speech: Can rabies be eradicated? C. Rupprecht (CDC, USA) 14h00 - Rabies control in dogs Chairperson: F. Cliquet (AFSSA, France) - Rapporteur: B.A. Yakobson (KVI, Israël) 14h00 Molecular epidemiology of lyssaviruses in Eurasia 14h10 Identification of novel canine rabies virus L.M. McElhinney (VLA, UK) D. David, (KVI, Israël) clades in the middle east and north africa 2/7 Joint OIE/WHO/EU Conference on rabies, 27-30 May 2007 - Programme 14h20 Rabies in South Asia - Epidemiological C.K. Singh (RRDL, India) investigations 14h30 Stray dogs in Bangkok, Thailand: rabies virus S. Kasempimolporn (QSMI, Thailand) infection and rabies antibody prevalence 14h40 Preference for commercially produced oral D. Bergman (USDA, USA) rabies baits by feral dogs 14h50 Assessment of the efficacy of oral vaccination B.A. Yakobson (KVI, Israël) of shepherd dogs in supplement of oral rabies vaccination of wild canids in israel 15h00 Longterm immunization of recombinant rabies- R. Hu (AMMS,China) canine adenovirus type-2 in dogs after intranasal or oral vaccination 15h10 New steps in the control of canine rabies in India H.K. Pradhan (IVRI,India) F.-X. Meslin (WHO) 15h20 Rabies in Mexico, 1990-2005 C.H. Álvarez Lucas (SM, Mexico) 15h30 Risk of rabies introduction by non-commercial P. Have (EFSA) movement of pets 15h40 Discussion 16h00 Coffee break 16h30 - Rabies control in wildlife Chairperson: A.D. Botvinkin (ISMV, Russia) - Rapporteur: I. Kuzmin (CDC, USA) 16h30 Epidemiology of rabies in South East Europe N. Johnson (VLA, UK) 16h40 Rabies in Mongolian steppes A.D. Botvinkin (ISMV, Russia) 16h50 Epidemiology and control of rabies in Iran A.R. Janani (PI, Iran) 17h00 Rabies epidemiology in Raccoon Dogs and Foxes 17h10 Downside risk of wildlife translocation 17h20 Sylvatic rabies in Russia with special attention to A. Singer (CSL, UK) R. Chipman (USDA, USA) A.D. Botvinkin (ISMV, Russia) perspectives of oral vaccination of wild carnivores 17h30 Finnish-Russian collaboration programme on A. Metlin (FGI ARRIAH, Russia) rabies control in wildlife: the outcome of five years and the future prospects 3/7 Joint OIE/WHO/EU Conference on rabies, 27-30 May 2007 - Programme 17h40 Rabies eradication programme in Estonia by M. Laine (FB, Estonia) means of oral vaccination of wildlife: first results 17h50 Rabies surveillance in Poland between 1992 – M. Smreczak (NVRI, Poland) 2006 18h00 Efficacy of a square presentation of V-RG vaccine F. Cliquet (AFSSA, France) baits in red fox, domestic dog and raccoon dog 18h10 Scenario-analysis evaluating emergency strategies H.-H. Thulke (HCER, Germany) after rabies re-introduction 18h20 The financial challenge to keep a large region T. Müller (FLI, Germany) free of rabies – the EU example 18h30 What is the future of rabies control in Europe? 18h40 The strength of 70% - Revising a given threshold G. Smith (CSL, K) H.-H. Thulke (HCER, Germany) of rabies control 18h50 Discussion Tuesday, 29 May 2007 09h00 - Rabies in bats: an emerging zoonosis Chairperson: A.R. Fooks (VLA, UK) - Rapporteur: T. Müller (FLI, Germany) 09h00 A random grid based molecular epidemiological C. Freuling (FRIAH, Germany) study on EBLV isolates from Germany 09h10 Asymptomatic rhabdovirus infection in meridional J.E. Echevarría Mayo (ISC, Spain) serotine bats (Eptesicus isabellinus) from Spain 09h20 Public health hazard of European bat lyssavirus, W.H.M. Van der Poel (WUR, Netherlands) the Netherlands 09h30 Serological investigation of bats infected with C. Tu (AMMS, China) rabies virus in China 09h40 Epidemiology and pathogenicity of African bat L.H. Nel (UP, South Africa) lyssaviruses 4/7 Joint OIE/WHO/EU Conference on rabies, 27-30 May 2007 - Programme 09h50 Experimental infection of big brown bats I. Kuzmin (CDC, USA) (Eptesicus fuscus) with West Caucasian bat virus 10h00 Susceptibility of foxes (Vulpes vulpes) to European E. Picard, (AFSSA, France) bat lyssaviruses types-1 and -2 10h10 Identification of british bat species using sequence S.L. Harris (UB, UK) comparison and its application to european bat lyssavirus diagnosis and surveillance 10h20 Discussion 10h30 Coffee break 11h00 - Rabies prevention in humans Chairperson: F.-X. Meslin (WHO) - Rapporteur: Y. Rotivel (IP, France) 11h00 Human rabies includes early generalized R. Willoughby (CHW, USA) vasospasm of cranial arteries that responds to tetrahydrobiopterin, l-arginine or nitroprusside 11h10 Therapy of human rabies: lessons from experimental A.C. Jackson (KGH, Canada) studies in a mouse model 11h20 Rabies control and prevention in the republic of P. Imnadze (NCCD, Georgia) Georgia: current status and perspectives 11h30 A simplified economical 4-site intradermal M. Warrell (UO, UK) post-exposure rabies vaccine regimen is as immunogenic as the current intramuscular and intradermal methods 11h40 Single dose for rabies pre-immunization P. Khawplod (QSMI, Thailand) 11h50 Immune memory after remote pre- and H. Wilde (CU, Thailand) post-exposure rabies vaccination: a prospective study in thailand 12h00 Epidemiology and prophylaxis of rabies in humans Y. Rotivel (IP, France) in France. Evaluation and perspectives of a twenty five year surveillance program 12h10 Discussion 12h30 Lunch break 14h00 - Session 4 / Advances in technologies, diagnosis and vaccines Chairperson: N. Tordo (IP, France) - Rapporteur: T. Hemachuda (CU, Thailand) 5/7 Joint OIE/WHO/EU Conference on rabies, 27-30 May 2007 - Programme 14h00 Keynote speech: Immune evasion, a critical strategy for rabies virus 14h30 BHK-21 cell culture rabies vaccine- a candidate M. Lafon (IP, France) D. Lalosevic (FMNS, Serbia) vaccine for Humans 14h40 Factors influencing the antibody response to V. Jakel (JLU, Germany) rabies vaccination 14h50 Attaining raccoon rabies management goals: D. Slate (USDA, USA) history and challenges 15h00 Evaluation of the stability of rabies vaccine baits P. Maciulskis (LVA, Lithuania) field trial 15h10 Immunogenicity of ERA G 333 strain in foxes and D. Bankovskiy (ARRI, Russia) raccoon dogs 15h20 Canine adenovirus-based vaccines against rabies N. Tordo (IP, France) 15h30 Coffee break 16h00 Development of an edible rabies vaccine in maize, E. Loza-Rubio (NCVM, Mexico) using vnukovo strain 16h10 Genetically engineered single-chain antibody M. Mousli (IP, Tunisia) fusion proteins for detection of rabies virus antigen 16h20 Use of rabies virus as a transneuronal tracer of G. Ugolini (CNRS, France) neuronal connections: Implications for the understanding of rabies pathogenesis 16h30 Inhibition of rabies virus replication by Micro-RNA N. Israsena (CUHR, Thailand) 16h40 Discussion 17h00 Keynote speech: Rabies at the dawn of the 21st Century H. Koprowski (TJU, USA) Wednesday, 30 May 2007 09h00 - Session 5 / General conclusions and recommendations Chairperson: N. Belev (OIE) - Rapporteur: T. Müller (FLI, Germany) and A.R. Fooks (VLA, UK) 10h00 Coffee break 6/7 Joint OIE/WHO/EU Conference on rabies, 27-30 May 2007 - Programme 10h30 Report of the questionnaire on stray dog control S. Kahn (OIE, France) 10h40 Keynote speech: What have we achieved? The way forward D. Briggs (VMC, USA) 11h15 Announcement and video of the next conference 11h30 Closing of the conference 13h00 Press point 7/7