Dr. G.N. Singh, M.Pharm., Ph.D., MBA
Secretary-cum-Scientific Director,
Indian Pharmacopoeia Commission, Ghaziabad.
My name is G. N. Singh. I obtained my Ph.D. in Pharmaceutical sciences from Banaras
Hindu University, Varanasi, India in 1987 and MBA from University of Hull, U.K in 1998. I
have worked with M/s Indian drugs and pharmaceuticals Limited (IDPL), a Government of
India undertaking, Ministry of Chemicals and Fertilizers, Govt. Of India at the level of
various positions from Executive to Sr. Manager for 13 years and at Central Indian
Pharmacopoeial Laboratory (CIPL), Ministry of Health and Family Welfare, Govt. of India
as Director for 7 years. I have been appointed Secretary-cum-Scientific Director for Indian
Pharmacopoeia Commission on 9th September 2009. I am a member of various scientific
bodies of Govt. of India like Drugs Technical Advisory Board, Drugs Consultative
Committee, Pharmacy Council of India, Pharmacovigilance Programme of India, Expert core
Committee of National List of Essential Medicines, Jan Aushadhi Programme and in the
Board of various universities/ institutions. I am an active member of IPA, IPGA, Indian
Hospital Pharmacist Association and Indian Chemical Society etc. I have authored 75
publications in national and international journals of repute and also chaired various national
and international seminars.
RECENT UPDATES

Sixth edition of Indian Pharmacopoeia 2010

Fourth edition of National formulary of India 2010
PRIOR EXPERIENCE
About 22 years of experience as a Scientist, Technocrat and as administrator for various
activities related to manufacturing, testing, quality control and quality assurance of drugs and
pharmaceuticals.
Director, Central Indian Pharmacopoeial Laboratory, Ministry of Health and Family
Welfare, Govt. Of India, October 2002 to August 2009

Head of the institution, which is concerned with testing of samples of drugs as per
Drugs and Cosmetics Act 1940 and Rules 1945.
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
As Government analyst ensured that CIPL adhered to concept of highest standards in
quality of drug testing.
M/s India Drugs and Pharmaceuticals Limited (IDPL), Ministry of Chemicals and
Fertilizers, Govt. Of India, August 1989 to October 2002

Manager/Senior Manager
Scientific Management of Formulation Unit at IDPL, Gurgaon

Deputy Manager
Research and Development at IDPL corporate level
Quality Assurance at IDPL corporate level
Incharge for Product Development at IDPL, Gurgaon
Incharge Personnel and Administration department

Senior Executive
Research and Development at IDPL corporate level
Quality assurance at IDPL corporate level

Executive
Development and scaling up of tablets, capsules, dry syrups, liquids etc.,

Pool Officer, CSIR, New Delhi, August 1988-July 1989
Responsible for formulation development and research of new products mainly
consisting of solid-dosage forms, parenteral and other products

Research Associate, BHU, June 1987-July 1988
Research in area of Physical Pharmacy.
TEACHING EXPERIENCE

Teaching pharmacy graduates and post graduates in BHU, Varanasi.
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RESEARCH EXPERIANCE
M. Pharm, M. Tech. and Ph.D. students of the Indian Universities in the area of
pharmaceutical sciences and allied subjects.
Number of dissertations guided
: 25
PUBLICATIONS
Total Number of Papers published 75, Recent Publications details are appended below:1. P.K. Saini, R.M.Singh, C.L. Jain, S.C.Mathur, and G.N. Singh. Development and
Validation of RP-HPLC method for estimation of Efavirenz in bulk and in tablet
dosage forms [MS 10002].Journal of Pharmaceutical Research, Volume 9, No.2,
April 2010: 87-89.
2. Singh R.M., Saini P.K., Mathur S.C., Singh G.N. and Kumar Santosh. Application
of High Performance Liquid Chromatography to the Determination and Validation of
Levodopa in Methanolic extract of Mucuna utilis. International Journal of Green
Pharmacy, Volume 4, Issue 3, July-September 2010: 156-158.
3. P.K Saini, R.M Singh, C.L Jain, S.C Mathur and G.N Singh. A sensitive and
selective RP-HPLC method for the determination of lamivudine and stavudine in
tablets.Journal of Pharmacy Research, 2009, 2(10), 1598-1600.
4. Saini P. K., Jain C. L., Singh R.M., Mathur S. C. and Singh G. N. Development and
validation of Spectrophotometric method for estimation of Emtricitabine in bulk and
capsule dosage form.The Indian Pharmacist, August 2010, 61-64.
5. Saini P. K., Jain C. L., Singh R. M., Mathur S. C., Singh G. N., Naslam M. A simple
and sensitive HPTLC method for simultaneous determination of Abacavir sulphate
and
Lamivudine
in
pharmaceutical
dosage
form
[MS09203].Journal
of
Pharmaceutical Research Vol. 8, No. 4, October 2009: 187-191.
6. P. K. Saini, C. L. Jain, R.M. Singh, S. C. Mathur, G. N. Singh, M.
Naslam.Development and validation of a HPLC method for the simultaneous analysis
of Abacavir sulphate and Lamivudine in combined tablet dosage forms [Manuscript
ID 09- 0255].Pharmbit Vol. XX, No.2, Jul-Dec. 2009, 97-105.
7. Saini P.K., Jain C.L., Singh R.M., Mathur S.C. and Singh G.N. Quantification of
Vinorelbine in Bulk Drug and its Injection Dosage Form by RP-UPLC Method. The
Indian Pharmacist, July 2010, 50-55.
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8. P. K. Saini, C. L. Jain, R.M. Singh, S. C. Mathur, G. N. Singh. A Rapid and Sensitive
RP-UPLC Method for Simultaneous Determination of Zidovudine, Lamivudine and
Nevirapine in Tablet Dosage Form.Journal of Pharmaceutical Research April 2010,
Volume 9, No.2, 56-59.
9. Saini P. K., Jain C. L., Singh R. M., Mathur S. C., Singh G. N., Khar R. K., and
Hafeez A. Simultaneous Quantification of Artemether and Lumefantrine in Tablet
Dosage Form by RP-HPLC Method. Indian Drugs 47(4) April 2010.
10. Pawan K. S., R.M. Singh, S.C. Mathur, G.N. Singh, C.L. Jain, R.K. Khar, and Abdul
Hafeez. A Simple and Sensitive HPTLC Method for Quantitative Analysis of
Artemether and Lumefantrine in Tablets. Journal of Planar Chromatography 23
(2010) 2, 119-122.
11. P. K. Saini, C. L. Jain, R.M. Singh, S. C. Mathur, G. N. Singh. Rapid and Sensitive
RP-Ultra Performance Liquid Chromatography (UPLC) Method for Estimation and
Validation of Paclitaxel in Bulk and its Injection Dosage Form. Pharmabit Vol. XX,
No. 2, Jul-Dec. 2009, 143-147.
12. B. Lal, S. C. Mathur, R. M. Singh, P. K. Saini, O. Prakash, G. N. Singh.
Development and Validation of a RP-HPLC method for estimation of Montelukast
Sodium in Bulk and in Tablet Dosage Form. Indian J. Pharm. Sci., 2010, 72(2), 235237.
13. Saini P. K., Jain C. L., Singh R. M., Mathur S. C., Singh G. N. Reverse Phase-Ultra
Performance Liquid Chromatographic (UPLC) Method for determination and
validation of Irinotecan Hydrochloride in Bulk and its Injection Dosage Form. The
Indian Pharmacist Volume: VIII, No. 83, MAY 2009, 55-58.
14. Saini P. K., Khan S. , Prakash O., Singh R. M., Mathur S. C., Singh G. N. Khar R.
K. Simultaneous Determination of Simvastatin and Ezetimibe by RP-HPLC Method
in Tablet Dosage Form. Pharmabit Vol. XIX, No. 1, Jan-Jun, 2009,65-68.
15. P. K. Saini, C. L. Jain, R. M. Singh, S. C. Mathur, G.N. Singh, S. Tuteja, U.K. Singh.
Simultaneous Determination of Lamivudine and Zidovudine by HPTLC Method in
Tablet Dosage Form.PHARMABIT Vol. XIX, No. 1, Jan-Jun, 2009, 25-28.
16. Saini P. K., Singh R. M, Jain C. L., Mathur S. C., Singh G. N., Tuteja S., Singh U.K.,
and Prakash O. Simultaneous estimation of Lamivudine and Zidovudine in combined
dosage form using RPLC method. Indian Drugs 47(2) February 2010.
17. Yadav Alok, Singh R. M., Mathur S. C., Saini P.K., Prakash O., Singh G.N.
Simultaneous HPTLC method for estimation of Domperidone and Paracetamol in
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bulk and its tablet dosage forms. Journal of Planar Chromatography 22 (2009) 6, 421424.
18. Jain V.K., Vats A.R., Singh R.M., Mathur S.C., Kumar S., Sharma D.K., Prakash O.,
Singh G.N. Development and validation of HPLC method for the determination of
Donepezil hydrochloride in bulk and tablet dosage form. Indian Drugs, 46 (6),
2009,65-68.
19. Saini P.K., Jain C.L., Singh R.M., Mathur S.C. and Singh G.N. Development of a
simple HPLC method for the quantitation of Artemisinin in Artemisia Annua Herb. J.
Pharm. Res. 8(1), January 2009, 16-18.
20. Madan S., Singh G.N., Kumar Y., Kohli K., Singh R.M., Prakash O. Isoflavonoids
from Flemingia strobilifera (L) R.Br. Roots.Acta Poloniae Pharmaceutica, 2009,
Issue: 9.
21. Prakash O., Singh G.N., Singh R.M., Madan S., Mathur S.C. Study of the interactions
of herbal extracts in combination against the free radical scavenging activity.
Pharmaceutical Biology, 2009, 47 (5-6).
22. Goel A., Goel R., Singh G.N., Ahmad F.J., Singh R.M., Jain G.K. Development and
Validation of a stability indicating HPTLC method for analysis of 3-Acetyl-11-Ketoβ-Boswellic
acid
in
herbal
extract
and
nanoparticles
formulation.
Acta
Chromatographia 2008, 20(3), 495-509.
23. Yadav A., Singh R. M., Mathur S. C., Kumar S., Prakash O., Singh G.N.
Simultaneous estimation and validation of Domperidone and Paracetamol by RPHPLC method in bulk and its dosage form. Pharmabit, 2008, xvii (1), 83-86.
24. Madan S., Singh G.N., Kumar Y., Kohli K., Singh R.M., Mir S. R., Ahmed S. A new
Flavanone from Flemingia strobilifera (Linn.) R.BR. and its antimicrobial
activity.Tropical journal of Pharmaceutical Research, 2008, 7 (1), 921-927.
25. Prakash O., Singh G.N., Singh R. M., Mathur S. C., Bajpai M., Yadav S.
Determination of Bacoside A by HPTLC in Bacopa monnieri extract. International J.
Green Pharmacy, 2008, July-Sep, 173-175.
26. Prakash O., Singh G.N., Singh R. M., Mathur S. C., Bajpai M., Yadav S. Protective
effect of BCEZ, a herbal formulation against carbontetrachloride induced
hepatotoxicity. International J. Pharmacology, 2008, 4(4), 282-286.
27. Singh P., Bajpai M., Prakash O., Tiwari R., Mathur S.C., Singh R.M., Singh G.N.
High Performance Thin Layer Chromatographic method for the determination of
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Cinnamadehyde in Cinnamomum bark powder. J. Natural Remedies, 2008, 8(2), 179182.
28. Ganesh B., Pathak D.P., Singh R.M., Mathur S.C., Kumar S., Prakash O., Singh
G.N. High Performance liquid chromatographic method for the determination of
Trandolapril in bulk drug and tablet dosage forms. J. Pharmaceutical Research, 2008,
7(3), 145-147.
29. Singh R. M., Gupta P., Khosla P., Mathur S. C., Singh G. N. Formulation and
Evaluation of Ethyl Cellulose Coated Nimesulide Microcapsules: Influence of
Solvents. Indian Drugs 2008, 45(5), 370-375.
30. Prakash O., Singh R.M., Pandey M., Mathur S.C., Raj S., Singh G.N. Development
and Estimation of a Liquid Chromatographic Method for Fexofenadine HCl in
Tablets. Indian Drugs 2008, 45(2), 149-152.
31. Singh R. M., Khan R.,H., Talegaonkar S., Mathur S.C., Shiv Raj, Singh G.N. A
Simple HPLC Method for Quantification of Repaglinide in Tablet Dosage Form.
Indian Drugs, 2007, 44 (6), 428-433.
32. Singh P., Bajpai M., Prakash O., Matur S.C., Singh R.M., Tiwari R., Singh G.N.
Quantitative determination of Piperine in Piper longum powder through high
performance thin layer chromatography. J. Pharmaceutical Research, 2007, 6 (3),
170-172.
33. Om Prakash, Singh R.M., Mathur S.C., Singh G.N. Quantification of Gallic acid by
HPLC and Antioxidant activity of Amla fruits. J. Pharmaceutical Research, 2007, 6
(3), 161-162.
34. Singh R.M., Gupta S.K., Mathur S.C., Shiv R., Singh G.N. Quantitative
Determination of Thalidomide by Reverse Phase High Performance Liquid
Chromatography. J. Indian Council of Chemists, 2006, 22(2), 25-27.5.
35. Singh R.M., Mathur S.C., Shiv Raj, Singh G.N., Faisal M.S., Khar R.K. RP-HPLC
method for estimation of Modafinil in bulk drug. Indian Drugs, 2006, 43(6), 510-512.
36. Singh
R.M.,
Khan
H.R.,
Talegaonkar
S.,
Mathur
S.C.,
Singh
G.N.
Spectrophotometric Determination of Repaglinide in Pharmaceutical Dosage Form. J.
Phamraceutical Research, 2006, 5 (4), 111-112.
37. Singh R.M., Siddiqui A.A., Khar R.K., Mathur S.C., Shiv Raj, Singh G.N. A Simple
HPLC Method for Quantitative Determination of Nevirapine in Tablet Dosage Form.
J. Phamraceutical Research, 2006, 5 (4), 108-110.
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38. Singh R. M., Ansari T. A., Jamil S.,
Kumar Y., Mathur S. C., Singh G. N.
Spectrophotometric Estimation of Rosuvastatin Calcium in Tablet Formulation.
Indian Drugs 2005, 42 (4), 244-245.
39. Singh R. M., Ansari T. A., Jamil S., Mathur S. C., Shiv R., Singh G. N.
Determination of Etoricoxib in bulk drug and its dosage forms by RP-HPLC. Indian
Drugs 2005, 42 (1), 56-58.
40. Singh R.M., Jamil S., Ansari T. A., Mathur S. C., Nivoria C. S., Pandey M. K.,
Singh G. N. Determination of Rosuvastatin Calcium in Pharmaceutical Dosage Form
by RP-HPLC Method. Indian Drugs, 2005, 42(2), 98-101.
41. Singh R.M., Ansari T.A., Jamil S., Kumar Y., Sharma D.K., Mathur S.C.,
Singh G.N. Spectrophotometric Method for the Estimation of Etoricoxib in
Formulation. Indian Drugs, 2005, 42(8), 535-536.
42. Singh G.N. et al., Spectrophotometric determination of Fortidine in pharmaceutical
preparations. J. Pharm. Biomed. Anal. 1992, 10 (7), 521-23.
43. Singh G.N. et al., New titrimetric methods for the estimation of Diltiazem in dosage
forms. Indian J.Pharm. Sci., 1991, 53(5), 214-216.
44. Singh G.N. et al., Studies on the diclofenac sodium and determination in
Pharmaceuticals, Journal of Pharma. And Biomedical Analysis, 1991, 9(7), 101.
45. Singh G.N. and Gupta R.P. Adsorption characteristics of Norfloxacin to
pharmaceutical additives. Drug Dev. Ind. Phar., 1988, 14(13), 1845-1854.
46. Singh G.N., Gupta R.P. and Prakash P. Effect of ionic strength on the stability of
Norfloxacin. Pharmazie, 1988, 43, 134.
47. Singh G.N., Gupta R.P., Gulati R. Invitro studies of Phenothiazines with
pharmaceutical ingredients. Indian Drugs, 1988, 25 (6), 235-241.
48. Singh G.N., Gupta R.P. Role of antioxidants and preservatives on the stability of
drugs. The eastern pharmacist, 1988, 31 (365), 43-44.
49. Singh G.N., Prakash P. and Gupta R.P. Effect of pH on the stability of Butaperazine
dimaleate solution in water, Indian J.Pharm. Sci., 1988, 50(2), 122-124.
50. Singh G.N. and Gupta R.P. Effect of pH on the stability of Norfloxacin. The eastern
Pharmacist, 1988, 31 (365), 133-135.
51. Singh G.N., Gupta R.P. Effect of absorbents on permeation of Norfloxacin.
Pharmazie, 43, 699-700, 1988.
52. Singh G.N., Gupta R.P. Effect of ionic strength on the stability of Butaperazibe. The
Eastern pharmacist, 1988, 31 (366), 145-146.
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53. Singh G.N. and Gupta R.P. Effect of solvent composition on the stability of
Butaperazine dimaleate. Indian J.Pharm. Sci., 1988, 50(4), 242-244.
54. Singh G.N., Gupta R.P. Effect of solvents and additives on the stability of drugs.
Pharma Times, 1986, 18(7), 13-16.
55. Singh G.N., Gupta R.P. Stability of Pharmaceuticals. The Eastern pharmacist, 1987,
30 (356), 85-89.
56. Singh G.N., Gupta R.P., Singh N.K. Drug absorption through membranes. The
Eastern pharmacist, 1986, 29(243), 33-35.
57. Gupta R.P., Mandal M.K., Singh G.N. Adsorption interactions by pharmaceutical
ingredients. The Eastern Pharmacist, 1986, 29(334), 65-59.
58. Gupta R.P., Singh G.N. and Roy S.D. Role of isotopic dilution technique in analytical
and chemical assay of drugs. The pharmastudent, 1985-86, 23, 54-58.
59. Gupta R.P., Chandra S., Srivastava A.K., Singh O.N. and Singh G.N. Colorimetric
determination of Butaperazine dimeleate, The Eastern pharmacist, 1985, 28(322),
135-136.
60. Singh G.N., Singh V.P. and Gupta R.P. Colorimetric determination of promethazine
hydrochloride, Indian J.Pharm. Sci., 1984, 46(3), 125-125.
61. Gupta R.P., Gulati R., Singh G.N. and Srivastava A.K. Permeation study of
cholopromazine through poly dimethyl siloxane membrane, Indian J.Pharm. Sci.,
1984,46(4), 144-146.
62. Gupta R.P., Gulati R., Singh G.N. Effect of physico-chemical factors and additives
on permeation of Thioridazine hydrochloride through
poly dimethyl siloxane
membrane, The Eastern Pharmacist, 1984, 27(320), 223-226.
63. Gupta R.P., Gulati R., Zutshi A., Singh G.N. Reaction mechanism and colorimetric
determination of phenothiazines with p-Dimethyl amino benzaldehyde, Indian
J.Pharm. Sci., 1984, 46 (6), 216-218.
64. Singh G.N. et al., A novel drug delivery system for antihistaminic drugs, J. Phar. Sci.
in press.
SCIENTIFIC ACHIEVEMENTS

Publishing addendum 2002 to IP 1996 and addendum 2005

Fifth edition of IP in the form of IP 2007 and its addendum 2008

Sixth edition of IP 2010

Executed testing of statutory and non-legal samples of drugs in CIPL
8

Certification and validation of IP Reference Substances
HONOURS AND AWARDS
(i)
Passed 'C' Certificate of NCC.
(ii)
Passed Certificate and Diploma Course in Yoga.
(iii)
External Examiner - Indian Universities conducting Pharmacy Courses.
(iv)
Referee, Journal of Indian Chemical Society, Calcutta.
(v)
Countries visited for various scientific and managerial activities viz. Singapore.
Thailand, United Kingdom, Netherlands, France, former USSR and Switzerland
(vi)
Empanelled as an Expert Member- WHO, UNIDO in Pharmaceutical Technology.
(vii)
Chaired a number of National/International conferences/seminars/ symposia.
(viii) At the Board of Academic Institutions running pharmacy courses of the U.P. Tech.
University, Lucknow.
(ix)
Member editorial board of the Indian Drugs.
(x)
GLP Inspector, National GLP Compliance Monitoring Authority, Dept. of Science
and Technology, New Delhi.
(xi)
Member of the Appellate Committee, AICTE, New Delhi
Dr. G.N. Singh, M.Pharm., Ph.D.,
Secretary-cum-Scientific Director,
Indian Pharmacopoeia Commission, Ghaziabad.
Ministry of Health & Family Welfare, Govt. of India
Sector 23, Raj Nagar, Ghaziabad- 201 002,
INDIA.
Phone: +91-120-2783401,
FAX :+91-120- 2783311,
E.mail : ipclab@vsnl.net
Website : www.ipc.gov.in
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