PUBLICATIONS and PATENTS
20- Yann Astier, Denis E. Kainov, Hagan Bayley, Roman Tuma, Stefan
Howorka,”Stochastic Detection of Motor Protein-RNA Complexes by single channel
current recording” Chem. Phys Chem. 2007, 8, 2189 – 2194.
19- Haichen Wu, Yann Astier, Giovanni Maglia, Ellina Mikhailova and Hagan Bayley
“-Hemolysin pores with covalently attached molecular adapters” J. Am. Chem. Soc.(
2007), 129 (51), 16142-16148.
18- Hugh Martin,†,§ Helen Kinns,†,§ Nick Mitchell,† Yann Astier,‡ Hagan Bayley,‡ Stefan
Howorka†, “Nanoscale protein pores modified with PAMAM dendrimers” J. Am. Chem.
Soc.( 2007), 129 (31), 9640 -9649
17- A 'pore' man's sequencing solution? Michael Eisenstein, Nature Methods, Research
Highlights, 3, 157 (2006). Covering Astier et al. J. Am. Chem. Soc. (2006), 128(5) 17051710
16- Yann Astier, Orit Braha, Hagan Bayley, “Towards single molecule DNA sequencing:
direct identification of 5’ monophosphate ribo and deoxy-ribo nucleotides with a protein
nanopore equipped with a molecular adapter.” J. Am. Chem. Soc. (2006), 128(5) 17051710
15- Yann Astier, Hagan Bayley, Stefan Howorka, “Protein components for nanodevices”
Curr Opin Chem Biol 2005, 9:576-584.
14- Yann Astier, Gerard W. Canters, Jason J. Davis, H. Allen O. Hill, Martin P. Verbeet,
Hein J. Wijma, “Sensing nitrite through a pseudoazurin-nitrite reductase electron transfer
relay “ Chem. Phys. Chem. 2005, 6, 1114-1120.
13- Y. Astier*, A. Bond, H. Wijma, G. W. Canters, H. A. O. Hill, J. J. Davis. A
systematic study of the influence of peptide modification of a gold electrode on the
electrochemistry of pseudoazurin. Electroanalysis (2004), 16(13-14), 1155-1165.
(*corresponding author)
12- Y. Astier, P. N. Bartlett, “The measurement of alkaline phosphatase at nanomolar
concentration within 70 s using a disposable microelectrochemical transistor.”
Bioelectrochemistry (2004), 64(1), 53-59.
11- Y. Astier, P. N. Bartlett. The demonstration of an enhanced microelectrochemical
transistor for measurements in neutral solution at low analyte concentration.
Bioelectrochemistry (2004), 64(1), 15-22.
10- L. Andolfi, D. Bruce, S. Cannistraro, G.W. Canters, J.J. Davis, H.A.O. Hill, J.
Crozier, M. Ph. Verbeet, C.W. Wrathmell, Y. Astier. The electrochemical characteristics
of blue copper protein monolayers on gold. J. Electroanal. Chem. 2004, 565(1), 21-28.
9- Elizabeth. A. Bentley, Yann Astier*, Wen Ming Ji , Stephen. G. Bell, Luet-Lok Wong
and H. Allen O. Hill. The electrochemistry and scanning tunnelling microscopy of the
flavoprotein, putidaredoxin reductase on alkanethiol-modified gold. Inorganica Chimica
Acta, 2003, 356C, 343-348 (*corresponding author)
8- Astier, Yann; Balendra, Suki; Hill, H. Allen O.; Smith, Thomas J.; Dalton, Howard.
Cofactor-independent oxygenation reactions catalyzed by soluble methane
monooxygenase at the surface of a modified gold electrode. European Journal of
Biochemistry (2003), 270(3), 539-544.
7- Jacques Simonet, Yann Astier and Cecile Dano. On the cathodic behavior of
tetraalkylammonium cations at a platinum electrode. J. Electrochem. Soc., 451 (1998), 59.
6- P.N.Bartlett and Y.Astier. Microelectrochemical enzyme transistors. Chem. Commun.,
2000, 105-112.
PATENTS
5- UK Patent application on “covalently attached cyclodextrin adapter inside the hemolysin nanopore” filed june 2007 by Isis Innovation
4- UK Patent application on “single molecule DNA sequencing “
International Patent Application number PCT/GB06/004265 filed on 15 November
2006 by Isis Innovation LICENCED BY OXFORD-NANOLABS JUNE 2007
3- M. Hyland, Y. Astier, “Electrochemical sensor” Oxford-Biosensors patent file n 6,
Agent number 84036, No 0211449.4
Application: WO 2005-GB2544 20050629. Priority: GB 2004-14551 20040629.
2-Patent Analyte Measurement, SET & Area Compensation
Emma Wallace, Yann Astier
Priority UK 0211449.4
17/05/2002
PCT/GB2003/002150
16/05/2003
1-Patent Micro-ring Well Electrodes, Well Electrodes
Mark Hyland, Kevin Lorimer, Neil Butler, Emma Wallace, Yann Astier
Priority UK 0130684.4
21/12/2001
PCT/GB02/005911 23/12/2002