Fact Sheet on Narcotic Analgesics (Opiates) What are Opioids? According to the National Institute on Drug Abuse website, opioids Also known as “opiates,” are a class of drugs with powerful pain-relieving properties. Several of these are prescribed by doctors such as percocet, vicodin, and codeine. But there also exist opiates such as heroin, which in many countries is considered illicit (NIDA, 2011). Types of Opiates According the LIVESTRONG website, opiate drugs: Are extracted from poppies grown mostly in the Middle East and Southeast Asia. Opium and its derivatives temporarily block pain. Drowsiness, abnormally contracted pupils and facial scratching are signs of opiate use. Abrupt withdrawal of these drugs causes flu-like symptoms: sweating, muscle aches, abdominal cramps and vomiting. Because opiates are central nervous system depressants, an overdose can lead to coma and death. Codeine, thebaine and morphine are derived from opium; heroin is derived from morphine. These are opiate drugs. They bind to opioid receptors in the body, producing dependence, tolerance and addiction, as do other non-opiate semi-synthetic opioids (Demand Media Inc., 2011). Prescription and Illicit Opiates The Employee Drug Testing Ace website provides a list of both licit and illicit drugs: Licit Codeine Morphine Oxycontin Vicodin Hydrocodone Illicit Heroin ( EDTA, 2011) Street Names for Opiates The Employee Drug Testing Ace website also provides several street names for opiate based drugs: Captain Cody Loads Killer Shit Skag Vike Oxy ( EDTA, 2011). Therapeutic Uses of Prescription Opiates: According to our text, opioid’s most common clinical use is to relieve pain ( 2009). Narcotic analgesics are effective against most varieties of pain ( 2009). When given in a high enough dose narcotics can relieve the intense pain that is found with some types of cancer. (2009). Certain opioids are also used to suppress the coughing center of the brain ( 2009). In this manner, they are used as anti-tussives. Codeine is frequently includes in cough medicine ( 2009). Due to their constipating nature, opioid narcotics are also used to relieve diarrhea.(2009). Physiological effects from the abuse of sedative hypnotics, both primary and secondary or side effects Euphoria drowsiness impaired coordination dizziness confusion nausea sedation feeling of heaviness in the body slowed or arrested breathing constipation endocarditis hepatitis fatal overdose ( USDHHS, 2011) Withdrawal Effects from Opiates Early symptoms of withdrawal include: Agitation Anxiety Muscle aches Increased tearing Insomnia Runny nose Sweating Yawning Late symptoms of withdrawal include: Abdominal cramping Diarrhea Dilated pupils Goose bumps Nausea Vomiting Symptoms usually start within 12 hours of last heroin usage and within 30 hours of last methadone exposure ( USDHHS, 2011) Treatment Approaches to Opiate Abuse and Dependence The most common treatments involve supportive care and medications. The most commonly used medication, clonidine, primarily reduces anxiety, agitation, muscle aches, sweating, runny nose and cramping (USDHHS, 2011). .Buprenorphine (Suptex) has been shown to work better than other medications, including clondine for treating withdrawal from opiates, and can shorten the length of detox. It may also be used for long-term maintenance like methadone (USDHHS, 2011). People withdrawing from heroin may be placed on long-term methadone maintenance. This involves slowly decreasing dosages of methadone over time, which helps reduce the intensity of withdrawal symptoms (USDHHS, 2011). Some drug treatment programs have widely advertised treatments for opiate withdrawal called detox under anesthesia or rapid opiate detox. Such programs involve placing a client under anesthesia and injecting large doses of opiate-blocking drugs, which will return the system to the proper functioning (USDHHS, 2011). There is no evidence that these programs actually reduce the time spent in withdrawal, and in some cases, they may increase the intensity of symptoms (USDHHS, 2011). Additionally, there have been several deaths associated with the procedures, particularly when they are done outside of the proper medical setting (USDHHS, 2011). References Demand Media Inc. ( 2011). Types of opiate drugs. Retrieved from http://www.livestrong.com/article/75425-types-opiate-drugs/#ixzz1J9KxyjsW Employee Drug Testing Ace. ( 2011). Opiates. Retrieved from http://www.employeedrug-testing-ace.com/employment-drug-screening-resources/employee-drugtesting-glossary/define-opiates-opi Hanson, G., &Fleckenstein, A., & Ventrally, P. (2009). Drugs and society. Sudbury, MA: Jones and Bartlett Publishers. National Institute on Drug Abuse. ( 2011). Opiates. Retrieved from http://teens.drugabuse.gov/blog/tag/opiates/ National Institute on Drug Abuse. ( 2011). Commonly abused drugs. Retrieved from http://www.drugabuse.gov/DrugPages/DrugsofAbuse.html US Department of Health and Human Services. ( 2011). Opiate withdrawal http://www.nlm.nih.gov/medlineplus/ency/article/000949.html