synthetic chromatography

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Prof. Wang, KT’s Publication papers
1. Chewn-Lang Ho, Yan-Ping Shih, Kung-Tsung Wang and Hui-Ming Yu,
Enhancing the hypotensive effect and diminishing the cytolytic activity of hornet
mastoparan B by D-amino acid substitution, Toxicon, 2001, 39, 1561-1566
2. Hsing-Pang Hsieh, Ying-Ta Wu, Shui-Tein Chen and Kung-Tsung Wang, Direct
solid-phase synthesis
of octreotide
conjugates:
precursors for use as
tumor-targeted radiopharmaceuticals, Bioorganic & Medicinal Chemistry, 1999, 7,
1797-1803
3. Jiaang WT, Hsiao KF, Chen ST, Wang KT, Facile synthesis of a glycopeptide
building block of antifreeze glycoprotein, SYNTHESIS-STUTTGART , 1999 , 9,
1687-1690
4. Chen ST, Yu HM, Chen ST, Wang KT, Microwave-assisted solid reaction:
Reduction of ketones using sodium borohydride JOURNAL OF THE CHINESE
CHEMICAL SOCIETY , 1999
, 46(4), 509-511
5. Chen ST, Wang KT,Chemo-enzymatic synthesis of optically active amino acids
and peptidesJOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1999, 46(3),
301-311
6. Juan HF, Hung CC, Wang KT, Chiou SH, Comparison of three classes of snake
neurotoxins by homology modeling and computer simulation graphics,
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
1999, 257(2), 500-510
7. Wu YT, Hsieh HP, Chen ST, Wang KT , Direct solid phase synthesis of
biologically active peptide alcohols, JOURNAL OF THE CHINESE CHEMICAL
SOCIETY, 1999 ,46(2), 135-138
8. Lin IC, Sookkheo B, Phutrakul S, Chen ST, Tseng MJ, Wang KT , Combinatorial
peptide library for probing the selectivity of the s-1 subsite of proteases,
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1999,46(2), 147-152
9. Yu HM, Chen ST, Tseng MJ, Chen ST, Wang KT , Microwave-assisted
heterogeneous benzil-benzilic acid rearrangement, JOURNAL OF CHEMICAL
RESEARCH-S, 1999, 1, 62-63
10. Cheng MC, Wang KT, Inoue S, Inoue Y, Khoo KH, Wu SH, Controlled acid
hydrolysis of colominic acid under microwave irradiation, ANALYTICAL
BIOCHEMISTRY, 1999, 267(2), 287-293
11. Sookkheo B, Phutakul S, Chen ST, Wang KT , Aspartase-catalyzed preparative
scale synthesis of N-15-aspartic acid, JOURNAL OF THE CHINESE
CHEMICAL SOCIETY, 1998 , 45(4), 525-528
12. Hsieh HP, Wu YT, Chen ST, Wang KT, Dihydropyran-2-carboxylic acid, a novel
bifunctional linker for the solid-phase synthesis of peptides containing a
C-terminal alcohol, CHEMICAL COMMUNICATIONS, 1998, 6, 649-650
13. Wu YT, Hsieh HP, Wu CY, Yu HM, Chen ST, Wang KT, Facile solid phase
synthesis of octreotide analogs using P-carboxybenzaldehyde as a novel linker to
anchor FMOC-threoninol to solid phase resins, TETRAHEDRON LETTERS,
1998, 39(13), 1783-1784
14. Huang HW, Chen WC, Wu CY, Yu HC, Lin WY, Chen ST, Wang KT, Kinetic
studies of the inhibitory effects of propeptides subtilisin BPN ' and Carlsberg to
bacterial serine proteases, PROTEIN ENGINEERING, 1997, 10(10), 1227-1233
15. Hsieh
HP,
Chen
ST,
Wang
KT,
Microwave
induced
synthesis
of
3,4-dihydro-2H-pyran-2-carboxaldehyde: A versatile linker for solid phase
combinatorial library, JOURNAL OF THE CHINESE CHEMICAL SOCIETY,
1997 , 44(6), 597-600
16. Chen ST, Tseng PH, Yu HM, Wu CY, Hsiao KF, Wu SH, Wang KT, The studies of
microwave effects on the chemical reactions, JOURNAL OF THE CHINESE
CHEMICAL SOCIETY, 1997, 44(3), 169-182
17. Chen ST, Yang MT, Wu SY, Wang KT, Protein engineering .3. Computer aided
design of disulfide-bond free cobra venom cardiotoxin with a novel conformation
and biological activity from synthetic peptides, JOURNAL OF THE CHINESE
CHEMICAL SOCIETY, 1997, 44(3), 331-335
18. Wu CY, Chen WC, Ho CL, Chen ST, Wang KT, The role of the N-terminal leucine
residue in snake venom cardiotoxin II (Naja naja atra), BIOCHEMICAL AND
BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 233(3), 713-716
19. Yu HM, Chen ST, Suree P, Nuansri R, Wang KT, Effect of microwave irradiation
on acid-catalyzed hydrolysis of starch, JOURNAL OF ORGANIC CHEMISTRY,
1996 , 61(26), 9608-9609
20. Hsiao KF, Yang FL, Wu SH, Wang KT, Selective monoacetylation of diol
compounds by Aspergillus niger lipase, BIOTECHNOLOGY LETTERS, 1996,
18(11), 1277-1282
21. Huang HW, Wang KT, Structural characterization of the metal binding site in the
cysteine-rich region of HIV-1 Tat protein, BIOCHEMICAL AND BIOPHYSICAL
RESEARCH COMMUNICATIONS, 1996, 227(2), 615-621
22. Hsiao KF, Chen ST, Wang KT, Wu SH, Lipase-assisted synthesis of
beta-Gal-(1->3)-GalNAc, SYNLETT, 1996 , 10, 966-&
23. Hsiao YM, Chuang CC, Chuang LC, Yu HM, Wang KT, Chiou SH, Wu SH ,
Protein engineering of venom toxins by synthetic approach and NMR dynamic
simulation: Status of basic amino acid residues in waglerin I, BIOCHEMICAL
AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 227(1), 59-63
24. Ho CL, Lin YL, Chen WC, Hwang LL, Yu HM, Wang KT , Structural
requirements for the edema-inducing and hemolytic activities of mastoparan B
isolated from the hornet (Vespa basalis) venom, TOXICON, 1996, 34(9),
1027-1035
25. Chen ST, Tsai CF, Wang KT , Incorporation of unnatural amino acid derivatives
into a peptide bond via an oxime ester catalysed by papain or lipase, CHEMICAL
COMMUNICATIONS, 1996 , 2, 165-166
26. Chuang LC, Chen PY, Chen CP, Huang TH, Wang KT, Chiou SH, Wu SH ,
Structural
analysis
of
a
biologically
active
echistatin
analogue
des(46-49)-[Ala(8,37)]-echistatin gamma with three disulfide bonds by 2D-NMR
and computer graphics, BIOCHEMICAL AND BIOPHYSICAL RESEARCH
COMMUNICATIONS, 1996 , 220(2), 246-254
27. Chiou AJ, Ong GT, Wang KT, Chiou SH, Wu SH , Conformational study of two
linear hexapeptides by two-dimensional NMR and computer-simulated modeling:
Implication for peptide cyclization in solution, BIOCHEMICAL AND
BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 219(2), 572-579
28. Wu CY, Chen ST, Ho CL, Wang KT, Engineering of cardiotoxin by chemical
synthesis .1. Rapid synthesis of fully active cardiotoxin II and IV of Taiwan cobra
venom, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1996 , 43(1),
67-71
29. Chuang CC, Huang WC, Yu HM, Wang KT, Wu SH, Conformation of Vespa
basalis
mastoparan-B
in
trifluoroethanol-containing
aqueous
solution,
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND
MOLECULAR ENZYMOLOGY, 1996, 1292(1), 1-8
30. Chuang LC, Yu HM, Chen CP, Huang TH, Wu SH, Wang KT, Determination of
three-dimensional solution structure of waglerin I, a toxin from Trimeresunts
wagleri, using 2D-NMR and molecular dynamics simulation, BIOCHIMICA ET
BIOPHYSICA
ACTA-PROTEIN
STRUCTURE
AND
MOLECULAR
ENZYMOLOGY, 1996 , 1292(1), 145-155
31. Wang SH, Kao HY, Chen ST, Wang KT, Direct measurement of enantiomeric
excess of synthetic tert-leucine with a chiral-ligand-exchange chromatography,
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1995, 42(6), 953-956
32. Ho
TL,
Liao
PY,
Wang
o-methyltyrosyl-p-nitrophenylalanines
KT,
Behavior
within
the
of
stereoisomeric
beta-cyclodextrin
cavity,
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS,
1995, 23, 2437-2438
33. Ho CL, Lin YL, Chen WC, Yu HM, Wang KT, Hwang LL, Chen CT,
Immunogenicity of mastoparan-b, a cationic tetradecapeptide isolated from the
hornet (vespa-basalis) venom, and its structural requirements, TOXICON, 1995,
33(11), 1443-1451
34. Chiou SH, Chuanag MH, Hung CC, Hung HC, Chen ST, Wang KT, Ho CL,
Inhibition of protein-kinase-c by snake venom toxins - comparison of
enzyme-inhibition, lethality and hemolysis among different cardiotoxin isoforms,
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, 1995 ,
35(5), 1103-1112
35. Liao SY, Ong GT, Wang KT, Wu SH, Conformation of polymyxin-b analogs in
dmso
from
BIOPHYSICA
nmr-spectra
and
molecular
ACTA-PROTEIN
modeling,
STRUCTURE
BIOCHIMICA
AND
ET
MOLECULAR
ENZYMOLOGY, 1995 , 1252(2), 312-320
36. Chen ST, Kao CL, Wang KT, Alkaline protease catalysis of a secondary amine to
form a peptide-bond, INTERNATIONAL JOURNAL OF PEPTIDE AND
PROTEIN RESEARCH, 1995, 46(3-4), 314-319
37. Hsiao KF, Yang FL, Wu SH, Wang KT, Effects of acyl-groups and ethanol ratios
on
lipase-catalyzed
regioselective
deacylation
in
peracylated
methyl
glycopyranosides, BIOTECHNOLOGY LETTERS, 1995, 17(9), 963-968
38. Chen ST, Chen SY, Tu CC, Chiou SH, Wang KT, Physicochemical properties of
alkaline serine proteases in alcohol, JOURNAL OF PROTEIN CHEMISTRY,
1995, 14(4), 205-215
39. Chen HP, Hsiao KF, Wu SH, Wang KT, Regioselectivity enhancement by
partial-purification of
lipase from aspergillus-niger,
BIOTECHNOLOGY
LETTERS, 1995 , 17(3), 305-308
40. Chen ST, Huang WH, Wang KT , Kinetic resolution of esters of amino-acids in
t-butanol containing 5-percent water catalyzed by a stable industrial alkaline
protease, CHIRALITY, 1994 , 6(7), 572-576
41. Chiou SH, Hung CC, Huang HC, Chen ST, Wang KT, Yang CC, Sequence
comparison and computer modeling of cardiotoxins and cobrotoxin isolated from
taiwan
cobra,
BIOCHEMICAL
AND
BIOPHYSICAL
RESEARCH
COMMUNICATIONS, 1995, 206(1), 22-32
42. Ong
GT,
Chang
KY,
Wu
SH,
Wang
KT
,
Preparation
of
2,3,6,2',3',4',6'-hepta-o-acetyl-maltose/cellobiose by enzymatic- hydrolysis of
maltose/cellobiose octaacetate, CARBOHYDRATE RESEARCH, 1994 , 265(2),
311-318
43. Chen ST, Huang WH, Wang KT, Resolution of amino-acids in a mixture of
2-methyl-2-propanol water (19/1) catalyzed by alcalase via in-situ racemization of
one antipode mediated by pyridoxal 5-phosphate, JOURNAL OF ORGANIC
CHEMISTRY, 1994, 59(25), 7580-7581
44. Chen ST, Chen SY, Kao CL, Wang KT, Improved yield by cryoeffect in
kinetically
controlled
peptide-synthesis
catalyzed
with
alcalase,
BIOTECHNOLOGY LETTERS, 1994, 16(10), 1075-1080
45. Chen ST, Yang MT, Wu CY, Wang KT, Engineering of cyclic-peptides with novel
inhibiting properties to differentiate 2 serine proteases, chymotrypsin-carlsberg
and
subtilisin-carlsberg,
BIOORGANIC
&
MEDICINAL
CHEMISTRY
LETTERS, 1994, 4(17), 2123-2128
46. Chen ST, Chen SY, Chou SH, Chen CR, Huang WC, Wang KT, One-pot selective
deuteriation
of
5'-dimethoxytritylated
deoxynucleotide
derivatives,
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4(6), 789-794
47. Chen PY, Wu SH, Wang KT, Chemical synthesis of gamma-echistatin analogs elucidation of status of c-terminal-(45-49), PROTEIN ENGINEERING, 1994,
7(7), 941-944
48. Haiao KF, Lin HJ, Leu DL, Wu SH, Wang KT, Kinetic-study of deacetylation and
acetyl migration of peracetylated 1-methyl alpha, beta-d- glucopyranosides by
candida
lipase-catalyzed
hydrolysis,
BIOORGANIC
&
MEDICINAL
CHEMISTRY LETTERS, 1994, 4(13), 1629-1632
49. Ho CL, Hwang LL, Lin YL, Chen CT, Yu HM, Wang KT , Cardiovascular effects
of mastoparan-b and its structural requirements, EUROPEAN JOURNAL OF
PHARMACOLOGY, 1994, 259(3), 259-264
50. Chen ST, Chen SY, Chen SJ, Wang KT , Vinyl carboxylate, an acylating reagent
for selective acylation of amines and diols, LETTERS, 1994 , 35(21), 3583-3584
51. Chen ST, Duh SC, Wang KT , Facile synthesis of l-malic acid by a consecutive
enzymatic-reaction, BIOTECHNOLOGY LETTERS, 1994 ,16(4), 355-358
52. Chen ST, Tsai CF, Wang KT , Resolution of n-protected amino-acid derivatives in
supercritical
carbon-dioxide
catalyzed
by
alcalase,
BIOORGANIC
&
MEDICINAL CHEMISTRY LETTERS, 1994 , 4(4), 625-630
53. Chen ST, Chen SY, Kao CL, WangKT , Proline as nucleophile in kinetically
controlled peptide-synthesis catalyzed by alcalase in 2-methyl-2-propanol,
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4(3), 443-448
54. Hsiao KF, Wu SH, Wang KT , Regioselective deacetylation of secondary acetyl
esters in peracetylated methyl glucopyranosides by aspergillus-niger lipase,
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3(10),
2125-2128
55. Duh SC, Hsieh HZ, Chen ST, Wang KT , Facile peptide-bond formation using
polystyrene-bound o-nitrophenol as an active ester, JOURNAL OF THE
CHINESE CHEMICAL SOCIETY, 1993, 40(5), 475-479
56. Chen ST, Chang CM, Lin SL, Wang KT , Enantioselective hydrolysis of
2-aryloxypropionyl derivatives by penicillin-v amidase, JOURNAL OF THE
CHINESE CHEMICAL SOCIETY, 1993, 40(5), 489-491
57. Chen ST, Jang MK, Wang KT , Facile amide bond formation from esters of
amino-acids and peptides catalyzed by alkaline protease in anhydrous tert-butyl
alcohol using ammonium-chloride triethylamine as a source of nucleophilic
ammonia, SYNTHESIS-STUTTGART, 1993, 9, 858-860
58. Chen ST, Chen SY, Tu CC, Wang KT, Investigation of the conformation,
solubility, structure and selectivity of alkaline proteases in anhydrous alcohols,
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993 , 3(8),
1643-1648
59. Chen ST, Chen HJ, Yu HM, Wang KT, Facile synthesis of a short peptide with a
side-chain-constrained structure, JOURNAL OF CHEMICAL RESEARCH-S,
1993, 6, 228-229
60. Chen ST, Wu SY, Cheln SY, Wang KT, Alcalase catalyzed peptide-bond formation
between asp and d-ala in anhydrous t-butanol, BIOTECHNOLOGY LETTERS,
1993 , 15(4), 373-376
61. Chen ST, Tu CC, Wang KT, Selective incorporation of d-amino-acid esters into
peptides catalyzed by alcalase in t-butanol, BIOORGANIC & MEDICINAL
CHEMISTRY LETTERS, 1993, 3(4), 539-542
62. Chen ST, Chen SY, Chen HJ, Huang HC, Wang KT, Probing the s-1' subsite
selectivity of
an
industrial
alkaline
protease
in
anhydrous
t-butanol,
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3(4), 727-733
63. Ong GT, Chang KY, Wu SH, Wang KT, Selective deacylation on the glucosyl
moiety of octa-o-acetylsucrose by enzymatic-hydrolysis - formation of
2,1',3',4',6'-penta-o-acetylsucrose, CARBOHYDRATE RESEARCH, 1993, 241,
327-333
64. Yu HM, Wu TM, Chen ST, Ho CL, Her GR, Wang KT, Mastoparan-b, synthesis
and
its
physical
and
biological
properties,
BIOCHEMISTRY
AND
MOLECULAR BIOLOGY INTERNATIONAL, 1993, 29(2), 241-246
65. Chen PY, Wu SH, Wang KT, Double enantioselective esterification of racemic
acids and alcohols by lipase from candida-cylindracea, BIOTECHNOLOGY
LETTERS, 1993, 15(2), 181-184
66. Wu SH, Ong GT, Hsiao KF, Wang KT, Regioselective reactions of
monosaccharides and disaccharides by enzymes, JOURNAL OF THE CHINESE
CHEMICAL SOCIETY, 1992, 39(6), 675-682
67. Chen ST, Wang KT, Peptide-synthesis in organic-solvents catalyzed by an
industrial alkaline protease alcalase, JOURNAL OF THE CHINESE CHEMICAL
SOCIETY, 1992, 39(6), 683-691
68. Chesn ST, Lin SL, Hsiao SC, Wang KT, One-pot synthesis of cathepsin inhibitors
- n-alpha-protected n-peptidyl-o-acetyl hydroxylamines catalyzed by alcalase
followed by lipase in anhydrous t-butanol, BIOORGANIC & MEDICINAL
CHEMISTRY LETTERS, 1992, 2(12), 1685-1690
69. Chen ST, Chen SY, Wang KT, Kinetically controlled peptide-bond formation in
anhydrous alcohol catalyzed by the industrial protease alcalase, JOURNAL OF
ORGANIC CHEMISTRY, 1992, 57(25), 6960-6965
70. Chen LY, Leu WM, Wang KT, Lee YHW, Copper transfer and activation of the
streptomyces apotyrosinase are mediated through a complex-formation between
apotyrosinase and its transactivator melc1, JOURNAL OF BIOLOGICAL
CHEMISTRY, 1992, 267(28), 20100-20107
71. Yu HM, Chen ST, Wang KT, Enhanced coupling efficiency in solid-phase
peptide-synthesis by microwave irradiation,
JOURNAL OF ORGANIC
CHEMISTRY, 1992, 57(18), 4781-4784
72. Wu CY, Chen ST, Chiou SH, Wang KT, Kinetic-analysis of duck epsilon-crystallin
with l-lactate dehydrogenase-activity - determination of kinetic constants and
comparison of substrate-specificity, BIOCHEMICAL AND BIOPHYSICAL
RESEARCH COMMUNICATIONS, 1992, 186(2), 874-880
73. Chen HP, Wu SH, Tsai YC, Yang YB, Wang KT, Enantioselective deprotection of
n-protected amino-acids by d-aminoacylase, BIOORGANIC & MEDICINAL
CHEMISTRY LETTERS, 1992, 2(7), 697-700
74. Chiou AJ, Wu SH, Wang KT, Enantioselective hydrolysis of hydrophobic
amino-acid derivatives by lipases, BIOTECHNOLOGY LETTERS, 1992, 14(6),
461-464
75. Chen
ST,
Tu
CC, Wang
KT,
Facile
preparation
of
optically pure
[alpha-h-2]-alpha-amino acids, BIOTECHNOLOGY LETTERS, 1992, 14(4),
269-274
76. Wu CY, Chen WC, Yu HM, Chen ST, Wang KT, Side reactions in
peptide-synthesis - failure of coupling in solid-phase automatic synthesis of a
fragment (sequence-65-74) of the acyl carrier protein, JOURNAL OF THE
CHINESE CHEMICAL SOCIETY, 1992, 39(2), 195-198
77. Wu CY, Chen ST, Chiou SH, Wang KT, Facile synthesis of chiral 2-hydroxy acids
catalyzed by a stable duck epsilon-crystallin with endogenous l-lactate
dehydrogenase-activity, FEBS LETTERS, 1992, 301(2), 219-222
78. Wu CY, Chen ST, Chiou SH, Wang KT, Specific peptide-bond cleavage by
microwave irradiation in weak acid-solution, JOURNAL OF PROTEIN
CHEMISTRY, 1992, 11(1), 45-50
79. Chen ST, Hsiao SC, Chiou AJ, Wu SH, Wang KT, Industrial protease alcalase as a
catalyst in organic-synthesis - resolution of natural and unnatural amino-acids,
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1992, 39(1), 91-99
80. Ong GT, Wu SH, Wang KT, Preparation of 2,3,6,3',4'-penta-o-acetyl sucrose, the
precursor of sucralose, by enzymatic methods, BIOORGANIC & MEDICINAL
CHEMISTRY LETTERS, 1992, 2(2), 161-164
81. Chen ST, Hsiao SC, Chang CH, Wang KT , Chemoenzymatic synthesis of
fmoc-peptide fragments , SYNTHETIC COMMUNICATIONS, 1992, 22(3),
391-398
82. Chen ST, Chen SY, Hsiao SC, Wang KT, Application of industrial protease
alcalase in peptide-synthesis, BIOMEDICA BIOCHIMICA ACTA, 1991,
50(10-11), S181-S186
83. Chang KY, Wu SH, Wang KT, Regioselective enzymatic deacetylation of
octa-o-acetylsucrose - preparation of hepta-o-acetylsucroses, CARBOHYDRATE
RESEARCH, 1991, 222, 121-129
84. Lin SL, Chiou AJ, Wu SH, Wang KT, Enantiomeric separation of
2-(phenoxy)propionate
derivatives
by
chiral
high-performance
liquid-chromatography, CHIRALITY, 1991, 3(6), 476-479
85. Wong CH, Wang KT , New developments in enzymatic peptide-synthesis, 1991,
47(11-12), 1123-1129
86. Chen ST, Chen SY, Hsiao SC, Wang KT , Kinetic resolution of n-protected
amino-acid esters in organic-solvents catalyzed by a stable industrial alkaline
protease, BIOTECHNOLOGY LETTERS, 1991, 13(11), 773-778
87. Chen ST, Hsiao SC, Wang KT , Stable industrial protease catalyzed peptide-bond
formation in organic-solvent, BIOORGANIC & MEDICINAL CHEMISTRY
LETTERS, 1991 , 1(9), 445-450
88. Wu SH, Chu FY, Wang KT , Reversible enantioselectivity of enzymatic-reactions
by media, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1991, 1(7),
339-342
89. Chen ST, Chang CH, Wang KT , Facile synthesis of n-protected peptide-fragments
using polymer-bound 1-hydroxybenzotriazole as an active ester, JOURNAL OF
CHEMICAL RESEARCH-S, 1991, 8, 206-207
90. Wu SH, Chu FY, Chang CH, Wang KT , The synthesis of d-isoglutamine by a
chemoenzymatic method, TETRAHEDRON LETTERS, 1991, 32(29), 3529-3530
91. Wu CY, Chen ST, Chiou SH, Wang KT, Enzymatic-synthesis of argininosuccinate
catalyzed by delta-crystallin, BIOTECHNOLOGY LETTERS, 1991, 13(6),
405-410
92. Chang KY, Wu SH, Wang KT, Preparation of hepta-0-acetylsucroses and
hexa-0-acetylsucroses
by
enzymatic-hydrolysis,
JOURNAL
OF
CARBOHYDRATE CHEMISTRY, 1991, 10(2), 251-261
93. Chen ST, Wu SH, Wang KT, Diastereoselective hydrolysis of peptide esters by
alkaline protease - preparation of racemization-free peptides, INTERNATIONAL
JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1991, 37(4), 347-350
94. Lin SL, Chen ST, Wu SH, Wang KT, Separation of aspartame and its precursor
stereoisomers by chiral chromatography, JOURNAL OF CHROMATOGRAPHY,
1991, 54(1-2), 392-396
95. Wu SH, Lai SY, Lin SL, Chu FY, Wang KT , Direct measurement of enantiomeric
ratios of enzymatic resolution by chiral high-performance liquid-chromatography,
CHIRALITY,
1991, 3(1), 67-70
96. Chen ST, Chiou SH, Wang KT , Enhancement of chemical-reactions by
microwave irradiation, JOURNAL OF THE CHINESE CHEMICAL SOCIETY,
1991, 38(1), 85-91
97. Chen ST, Wang KT , Facile synthesis of biologically-active peptides using
phase-transfer reagents as c-terminal protecting group, JOURNAL OF THE
CHINESE CHEMICAL SOCIETY, 1991, 38(1), 93-96
98. Chen ST, Wang KT,
Phase-transfer reagents as c-terminal protecting groups -
facile incorporation of free amino-acids or peptides into peptide sequences,
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS,
1990, 15, 1045-1047
99. Chen ST, Chang CH, Lin J, Wang KT, Selective alkaline protease
catalyzed-hydrolysis of peptide esters, JOURNAL OF THE CHINESE
CHEMICAL SOCIETY, 37(3), 299-305
100. Chen ST, Chiou SH, Wang KT, Preparative scale organic-synthesis using a
kitchen
microwave-oven,
JOURNAL
OF
THE
CHEMICAL
SOCIETY-CHEMICAL COMMUNICATIONS, 1990, 11, 807-809
101. Ho CL, Ko JL, Hwang LL, Wang KT, Analgesic, receptor-binding, and
peripheral opioid activities of synthetic dermorphin-dynorphin hybrid peptides,
INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH,
1990, 35(2), 99-104
102. Chen ST, Lo LC, Wu SH, Wang KT, Side reaction in peptide-synthesis formation of oxazolidone derivatives, INTERNATIONAL JOURNAL OF
PEPTIDE AND PROTEIN RESEARCH, 1990, 35(1), 52-54
103. Chen ST, Wu SH, Wang KT, A new synthesis of o-benzyl-l-threonine,
SYNTHETIC COMMUNICATIONS, 1989, 19(20), 3589-3593
104. Shi FK, Lin YC, Wang KT , Sequence determination of a tetrapeptide using
LONG-RANG
HETERONUCLEAR
SHIFT
CORRELATION
2D
NMR-SPECTROSCOPY, JOURNAL OF THE CHINESE CHEMICAL SOCIETY,
1989, 36(5), 423-428
105. Wu SH, Lo LC, Chen ST, Wang KT, Manipulation of enzymatic regioselectivity
by structural modification of substrates, JOURNAL OF ORGANIC CHEMISTRY,
1989, 54(17), 4220-4222
106. Chiou SH, Wang K, Peptide and protein hydrolysis by microwave irradiation,
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1989
491(2), 424-431
107. Lo LC, Chen ST, Wu SH, Wang KT , Separation of diastereomers of protected
dipeptides by normal-phase high-performance liquid-chromatography, JOURNAL
OF CHROMATOGRAPHY, 1989, 472(1), 336-339
108. Chen ST, Wu SH, Wang KT, Rapid racemization of optically-active amino-acids
by microwave oven-based heating treatment, INTERNATIONAL JOURNAL OF
PEPTIDE AND PROTEIN RESEARCH, 1989, 33(1), 73-75
109. Yu HM, Chen ST, Chiou SH, Wang KT, Determination of amino-acids on
merrifield resin by microwave hydrolysis, JOURNAL OF CHROMATOGRAPHY,
1988, 456(2), 357-362
110. Chen
ST,
Wang
KT,
A
new
synthesis
of
o-benzyl-l-serine,
SYNTHESIS-STUTTGART, 1989, 1, 36-37
111. Chen ST, Wu SH, Wang KT, A simple method for amide formation from
protected amino-acids and peptides, SYNTHESIS-STUTTGART, 1989, 1, 37-38
112. Chiou SH, Wang KT, Simplified protein hydrolysis with methanesulphonic acid
at elevated-temperature for the complete amino-acid analysis of proteins,
JOURNAL OF CHROMATOGRAPHY, 1988, 448(3),
404-410
113. Chen ST, Wang KT, Papain-catalyzed synthesis of aspartame precursor in
biphasic system, JOURNAL OF ORGANIC CHEMISTRY, 1988, 53(19),
4589-4590
114. Chen ST, Li KF, Wang KT, Papain catalyzed synthesis of aspartyl dipeptides,
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1988 , 35(3), 207-211
115. Chu YH, Chen ST, Wang K T, Solution behavior of aromatic dipeptides .2. the
mechanistic aspect of the coupling reaction and conformation study of
diastereomers, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1988,
35(3), 213-217
116. Chen ST, Wang KT, Papain catalyzed esterification of n-protected amino-acids,
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS,
1988, 4,
327-328
117. Chen ST, Wang KT , Enzyme-catalyzed selective ester hydrolysis of aspartyl and
glutamyl dipeptide benzyl-esters, JOURNAL OF CHEMICAL RESEARCH-S,
1987, 9, 308-309
118. Wang SS, Chen ST, Wang KT, Merrifield RB, 4-methoxybenzyloxycarbonyl
amino-acids in solid-phase peptide-synthesis, INTERNATIONAL JOURNAL OF
PEPTIDE AND PROTEIN RESEARCH, 1987, 30(5), 662-667
119. Chen ST, Weng CS, Wang KT, The synthesis of rho-methoxybenzyloxycarbonyl
amino-acids, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1987, 34(2),
117-123
120. Chen ST, Chiou SH, Chu YH, Wang KT ,Rapid hydrolysis of proteins and
peptides by means
of microwave technology and its application to
amino-acid-analysis, INTERNATIONAL JOURNAL OF PEPTIDE AND
PROTEIN RESEARCH, 1987, 30(4), 572-576
121. Chen ST, Wang KT, The synthesis of beta-benzyl L-aspartate and gamma-benzyl
L-glutamate by enzyme-catalyzed hydrolysis, SYNTHESIS-STUTTGART, 1987,
6, 581-582
122. Chen ST, Wang KT, Wong CH , Chirally selective hydrolysis of d,l-amino
acid-esters
by
alkaline
protease,
JOURNAL
OF
THE
CHEMICAL
SOCIETY-CHEMICAL COMMUNICATIONS, 1986, 20, 1514-1516
123. Wang KT, Chen ST, Lo LC , The thin-layer chromatographic-separation of
enantiomeric dipeptides, FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE
CHEMIE, 1986, 324(3-4), 339-340
124. Lin DH, Tseng YS, Chien ST, Wang KT ,The synthesis of alanine oligopeptides,
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1985, 32(3), 365-371
125. Chu YH, Wang KT , H-1-NMR spectra of diastereomeric aromatic dipeptides
(phe-phe) in aqueous-solution, MAGNETIC RESONANCE IN CHEMISTRY,
1985, 23(6), 450-453
126. Chen ST, Wang KT, The synthesis of high-purity N-alpha- benzyloxycarbonyl
N-epsilon-tert-butyloxycarbonyl-l-Lysine, ORGANIC PREPARATIONS AND
PROCEDURES INTERNATIONA, 1983, 15(5),
361-364
127. Wu SH, Chen CJ, Tseng MJ, Wang KT, The modification of alpha-bungarotoxin
by digestion with trypsin, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS,
1983, 227(1), 111-117
128. Syu WJ, Wu SH, Wang KT, Purification of papain by affinity-chromatography,
JOURNAL OF CHROMATOGRAPHY, 1983, 262, 346-351
129. Wang KT, Wang WZ, Shen DK, Electron-spin-resonance of mn-2+ in as-se
glasses, JOURNAL OF NON-CRYSTALLINE SOLIDS, 1983, 56(1-3), 297-302
130. Wu SH, Chen CJ, Tsai YJ, Wang KT, Measurement of refolding rate of reduced
proteins
by
high-performance
liquid-chromatography,
ANALYTICAL
BIOCHEMISTRY, 1983, 129(2), 345-348
131. Tseng MJ, Wu SH, Wang KT , Enzymic-synthesis of oligopeptide .6. the
mechanistic features of pepsin-catalysed peptide-synthesis, TETRAHEDRON,
1983, 39(1), 61-66
132. Shen DK, Wang KT, Huang XH, Chen YX, Bai JH, Optical-absorption and
electron-spin-resonance of cu-2+ in sodium borosilicate glasses, JOURNAL OF
NON-CRYSTALLINE SOLIDS, 1982, 52(1-3), 151-158
133. Chen CS, Wu SH, Wang KT, Determination of esterase-activity of papain by
high-performance liquid-chromatography, JOURNAL OF CHROMATOGRAPHY,
1982, 248(3), 451-455
134. Chen CJ, Wu SH, Wang KT , Refolding of alpha-bungarotoxin and its
s-dicarboxymethylated derivative, BIOCHEMISTRY INTERNATIONAL, 1982,
5(3), 351-357
135. Wu SH, Wang KT, Ho CL, Purification and pharmacological characterization of
a cardiotoxin-like protein from formosan banded krait (bungarus-multicinctus)
venom, TOXICON, 1982, 20(4), 753-764
136. Wu SH, Tseng MJ, Wang KT , Separation of 4 cardiotoxins of taiwan cobra
(naja-naja atra) by reversed-phase high-performance liquid-chromatography,
JOURNAL OF CHROMATOGRAPHY, 1982, 242(2), 369-373
137. Chou SH, Wong CH, Chen ST, Wang KT, Enzymatic-synthesis of oligopeptide .2.
synthesis of bis-(n-protected amino-acid) hydrazides by papain, JOURNAL OF
THE CHINESE CHEMICAL SOCIETY, 1979, 26(1), 11-15
138. Wong
CH,
Wang
KT,
n-benzyloxycarbonyl-dl-amino
Mutual
resolution
of
acids,
JOURNAL
OF
dl-ephedrine
THE
and
CHINESE
CHEMICAL SOCIETY, 1978, 25(4), 209-214
139. Chou SH, Chen ST, Wong CH, Wang KT, enzymatic-synthesis of oligopeptide .1.
papain-catalyzed synthesis of dipeptide, tripeptide and tetrapeptide, JOURNAL
OF THE CHINESE CHEMICAL SOCIETY, 1978, 25(4), 215-218
140. Wong CH, Chen ST, Wang KT , Enzymic-synthesis of opioid peptides,
BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 576(1), 247-249
141. Wong CH, Wang KT, electrochemistry in organic-synthesis .1. large-scale
preparation of cysteine from cystine, JOURNAL OF THE CHINESE CHEMICAL
SOCIETY, 1978, 25(3), 149-151
142. Wong CH, Chen ST, Ho CL, Wang KT, synthesis of a fully active snake-venom
cardiotoxin by fragment condensation on solid polymer, BIOCHIMICA ET
BIOPHYSICA ACTA, 1978, 536(2), 376-389
143. WongG CH, Wang KT ,mutual resolution of (+)-ephedrine and z-dl-amino
acid-induced by seeding chiral salt, TETRAHEDRON LETTERS, 1978, 40,
3813-3816
144. Wong
CH,
Ho
MF,
Wang
KT
,preparation
of
optically
pure
n-tert-butyloxycarbonyl-o-benzyl-l-serine and its antipode, JOURNAL OF
ORGANIC CHEMISTRY, 1978, 43(18), 3604-3604
145. Wong CH, Ho CL, Wang KT ,purification of synthetic cardiotoxin by affinity
chromatography, JOURNAL OF CHROMATOGRAPHY, 1978, 154(1), 25-32
146. Wong CH, Chen YH, Hung MC, WANG KT, Ho CL, Lo TB,renaturation of a
reduced taiwan cobra cardiotoxin, BIOCHIMICA ET BIOPHYSICA ACTA, 1978,
533(1), 105-111
147. Wong CH, Chen ST, Wang KT ,resolution of amino-acids by enzymes .1.
proteolytic-enzyme bromelain for hydrolysis of l-amino-acid methyl-esters,
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1977, 24(3), 129-133
148. Kong FT, Lin TC, Wong CH, Wang KT, synthesis of taiwan cobra venom
cardiotoxin .2. synthesis of protected hexapeptide, sequence 44-49 and protected
tripeptide, sequence 50-52, JOURNAL OF THE CHINESE CHEMICAL
SOCIETY, 1976, 23(3), 155-164
149. Wang KT, Wong CH , chemical synthesis of taiwan cobra venom toxins,
TOXICON, 1976, 14(6), 420-420
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