GlaxoSmithKline-Sponsored ASLAP Foundation Summer Fellowship in Laboratory Animal Medicine at the University of Missouri Guidelines 1. VENUES and ACRONYMS 1) Externship/elective block activities occur primarily in four areas: i. The Office of Animal Resources (OAR) located at 1720 East Campus Loop animal facility management and oversight, animal care, laboratory animal medicine ii. The Research Animal Diagnostic Laboratory (RADIL) located at 4011 Discovery Drive - diagnostics, comparative and research pathology, animal resource centers, genetics, reproductive biology and cryobiology, extern/elective block projects iii. The Office of Animal Care and Quality Assurance (ACQA) – Animal Care and Use Committee, facility inspections, federal regulation compliance iv. Several research labs across campus – comparative medicine research 2. CONTACT INFORMATION 1) RULE NUMBER ONE (the only rule) is to drive your externship/elective block by asking questions, asking “what’s going on today,” etc. Do not wait for someone to come to you. There are several means of communicating with individuals in our program including email, cell phone and direct contact. If you have an accessible email account, we will use that; if not, we will establish an MU email account for you. The following email was used very successfully by a former extern to get things started: Hello everybody, My name is _______ and I'm a ____ year veterinary student from ______ on a ___ week externship/elective block here at the University of Missouri. I have met some of you already and am looking forward to meeting the rest of you soon. I would really appreciate it, if you have something interesting going on that you think I might benefit from, if you could send me an email or contact me and let me know about it. I would also like to participate in _______ if possible. My cell phone number is ______ and my email address is ______. I have desk space in _____ (RADIL) and the OAR postdoc office. If you know of anyone else who was not contacted in this email, but may be doing something of interest, please pass my information along. I'm looking forward to my stay in Columbia. 2) You will be balancing activities between the OAR, RADIL and research activities. Activities are a moving target and many are not scheduled so the challenge is finding out what is ongoing each day and then managing your day. You will be assigned a desk in the RADIL and one in the OAR. It is recommended that you spend your “downtime” at desks in both locations. Since OAR activities may arise at any time, it is recommended that, on days when no activities are scheduled, you spend the first hour of mornings at the OAR office desk. Moreover, to facilitate getting involved in OAR activities as soon as possible, schedule meetings with both Drs. Dixon and Korte sometime during the first week of your externship and consider spending the first 2-3 days of your externship at the OAR. 3) Work with Pat Parry and Rose Mayfield to get a University Pawprint which will get you access to computers (and an email if needed). You can also get wireless access by using the MizzouWireless-Guest access – ask Craig, Rose or Pat to obtain the WEP Key for the months you are here from Greg Kelly. 4) Your primary contacts for OAR, RADIL, ACQA and research activities are (additional contact information is at the end of this document): i. OAR - Dr. Scott Korte (OAR veterinarian), Drs. Glenn Jackson, Erin OConnor and Diana Gettys (postdocs doing their research but with some OAR activities). ii. RADIL – Veronica Adams (postdoc on RADIL rotation), Drs. Vinoth Sittaramane, Franklin Lopez and Marcus Crim (postdocs doing their research but with some RADIL activities), Laurie Wisdom (necropsy lab supervisor), Drs. Shari Hamilton and Susan Caraker (rodent pathologists; W191 Vet Med, 573-882-4472), Debbie Sharpe (PCR lab supervisor), Jill Gruenkemeyer (histology lab supervisor), and Janelle Lawrence (repro services and cryobiology lab supervisor) iii. ACQA – Sara Wolff, Holly Rice and Dr. Bill Dale, (573-884-6758) iv. OAR investigator support and med school surgeries – Sherri Neff (573-882-8495) v. Swine Center activities – Dr. Eric Walters (573-882-1134) vi. Research – Drs. Franklin Lopez, Marcus Crim, Vinoth Sittaramane, Glenn Jackson, Erin O’Connor, Diana Gettys, Ryan Stoffel, Chris Manuel, Bettina Weber, Hanni Lee, Aaron Ericsson, Lydia Cook and Mike Drake are all currently performing their dissertation or postdoctoral projects in a number of research labs across campus. vii. Contact these individuals on a daily/regular basis to find out about activities or with any questions you have. viii. Inquire about tours of facilities with OAR and RADIL contact persons. 5) Additional key contacts are i. Pat Parry, CMP fiscal person, S107 RADIL, 573-882-6647 ii. Rose Mayfield, extern travel coordinator, S115 RADIL, 573-884-7803 3. EXTERNSHIP/ELECTIVE GOALS Discuss your goals for this externship/elective with Dr. Franklin on day one. 4. PROJECT 1) During your externship / elective, you will perform a short benchtop research project (depending on project availability) i. Dr. Franklin will direct you to individuals with possible projects. Discuss these sometime during the first 2 days of your externship/elective block, so that you can get started as soon as possible. Again, drive your project, by asking lots of questions! At the end of your externship/elective, you will prepare a presentation describing your project. Include relevant background, objective or hypothesis, rationale, methods and design, results, conclusions and possible future directions. ii. If a project is not available, you will perform a literature review on the topic of your choice (approved by Dr. Franklin) and prepare a short (15-30 minute) presentation on a Comparative Medicine / Laboratory Animal Medicine topic. Determine the topic for the literature review based on your interests or observations during your first few days. iii. You will also have the opportunity to explore research by meeting with postdocs in their research labs and participate in their ongoing projects. 5. MEETINGS and ROUNDS Several meetings occur throughout the year that are of interest to externs/elective block students. Inquire with OAR and RADIL contacts about meetings as soon as you arrive. The following are scheduled meetings: 1) Animal Care and Use Committee meeting – First Tuesday of every month, (contact Sara Wolff, Holly Rice and Dr. Bill Dale for location and with questions) 2) OAR weekly postdoc meeting – Wednesdays at 12:00/12:15 in the OAR conference room 3) Pathology Rounds – Wednesdays at 8:15 in A251 Clydesdale (multiheaded scope room); we do not have rounds on block change day 4) OAR management meeting (Dr. Lon Dixon, postdocs, facility managers) – first Thursday of each month at 1:00/1:15 in OAR conference room; contact any OAR postdoc or Dr. Dixon for exact schedule 5) Helicobacter research lab meeting – Mondays at 8:30 in S102 RADIL. 6) Lab Animal Diagnostics lab meeting – Fridays at 9:00 in S102 RADIL 7) Comparative Medicine Seminar – Fridays at 12:00 in S130 RADIL 8) Core Course – fall, spring and summer semesters; Methodology of Animal Experimentation will begin January 19 (contact Dr. Franklin for more information). 9) Immunology journal club – Thursdays from 1-2 in 615 MSB (Med Sci Bldg) 10) Immunology works in progress – fall and winter semesters; every 1st, 3rd and 5th Tuesday at 4:00 in 615 MSB 11) AFIP pathology rounds – every Thursday at 9:00 in A251 Clydesdale (multiheaded scope room) – contact Dr. Gayle Johnson for information 12) Clinical pathology rounds – every Tuesday at 8:15 in clin path lab – contact Dr. Wiedmeyer for information 13) All of the postdocs that are in research labs have lab meetings – inquire if you’d like to attend one, two or all. 6. ONGOING ACTIVITIES 1) Animal care – schedule AT LEAST one day to shadow the OAR postdoc 2) Surgery labs – contact Sara Wolff, Holly Rice or Dr. Dale 3) Rodent handling labs – contact Holly Rice for more information. NOTE 1 - you will be asked to take and online course for which you will need a employee ID; if we cannot procure and ID prior to the lab, it is ok for you to take the course after the lab has been completed (once you have your ID); NOTE 2 - you may also be asked to participate in the Occupational Health Program – this is not necessary as you will not have time to fully go through the enrollment process. NOTE for MU elective block students; if a handling lab is not scheduled during your elective and you would still like to participate, you may do so through a future handling lab – contact Holly for handling lab schedules (let her know that this is part of a prior elective rotation). 4) Inspections – contact postdoc on OAR rotation(s), Sara and Holly. 5) ACUC protocol review – contact Dr. Pat Farrar 6) Surgeries – ongoing experimental surgeries will be discussed at OAR meetings or contact postdoc on OAR rotation or Sherrie Neff. 7) Parasitology and necropsy lab with follow-up tissue sectioning and histology lab – day one approx ½ day; days two and three – approximately 2 hours/day – contact Laurie Wisdom to schedule. 8) Rodent phenotyping lab – contact Laurie Wisdom to schedule 9) Reproductive biology and cryobiology activities (e.g. embryo transfer, ICSI, plug checks) – contact Janelle Lawrence 10) PCR lab – learn how to set up and run a PCR reaction – contact Dr. Livingston 11) Normal slide and disease slide set reviews. Drs Hamilton and Caraker have slide sets for rodents, rabbits, non-human primates and amphibians. After you have reviewed, please set up time with either to review slides and go over questions (approximately 1 hour/set). After slide set review, unknowns will be distributed for independent review. Once complete, again set up a time to review with Shari or Susan (1 hour) 12) Tour of genotyping lab and discussion of mouse, rat and swine resource centers – contact Dr. Bauer 13) Swine center activity and tours – contact Dr. Walters 14) Laboratory Animal Medicine class for the second year veterinary students – ongoing in January and February – contact Dr. Besch-Williford for details. 7. SPACE and TRAVEL 1) You will have access to computers and microscopes in the RADIL. You will also have access to the veterinary school library and a locker in the RADIL. 2) You will be assigned a desk in the RADIL and a desk in the OAR. It is recommended that you spend your “downtime” at desks in both locations (for example OAR in the morning and RADIL in the afternoon) so that you are readily available for activities that may arise. 3) You will be responsible for getting around on campus. This can either be accomplished by use of your personal vehicle or catching rides with postdocs and faculty (latter can be tough). If you need a parking pass for the day, contact Nancy Wawrzyniak. 4) Contact Rose Mayfield for a campus map 8. JOURNAL 1) Maintain a journal of your activities (to be handed in upon your departure). 2) To aid in keeping track of activities beforehand, consider making a schedule. 9. MEET PEOPLE 1) During your stay, you will have frequent contact with the CMP trainees. Also take advantage of our faculty that live and breathe Comparative Medicine. One means of doing so is to create a checklist and set up a time to meet with each individual and pick their brains about comparative medicine. Hint: if you ultimately plan to apply to our postDVM program, getting to know our faculty has its advantages. Below is a list that includes some (NOT all) background info. Beth Bauer, DVM, ACLAM, Assistant Professor, N133 RADIL (resource centers, rodent colony management, research and development) Cindy Besch-Williford, DVM, PhD, ACLAM, Associate Professor, N130 RADIL (comparative pathology, prostate cancer, immunohistochemistry and histology) Elizabeth Bryda, PhD, Associate Professor, N131 RADIL (genetics, genotyping, polycystic kidney disease, deafness) John Critser, PhD, Endowed Professor of Comparative Medicine, N132 RADIL (cryobiology, reproductive biology, biomedical engineering, resource centers) William Dale, PhD, Director of the Animal Care and Quality Assurance Office (ACUC, regulations) Lon Dixon, DVM, MS, ACLAM, Director of Animal Resources, 1720 E. Campus Loop (lab animal medicine, animal facility management, facility design, ACUC, pharmaceuticals and industry) Pat Farrar, DVM, ACLAM, Veterinarian, 1720 E. Campus Loop (ACUC protocol review) Craig Franklin, DVM, PhD, ACLAM, Associate Professor, N128 RADIL (comparative pathology, inflammatory bowel disease, helicobacters, rodent phenotyping and pathobiology, careers for veterinarians in research) Scott Korte, DVM, Manager, Clinical Veterinary Services, OAR, 1720 E. Campus Loop (laboratory animal veterinarian, genetically engineered swine) Mike Linville, DVM, Manager, Clinical Veterinary Services, OAR, 1720 E. Campus Loop (large animal veterinarian) Bob Livingston, DVM, PhD, ACLAM, Associate Professor, N127 RADIL (microbial diagnostics, PCR, recombinant antigens, murine norovirus, parvoviruses, helicobacters, R&D) Matt Myles, DVM, PhD, ACLAM, Research Assistant Professor, N134 RADIL (helicobacters, inflammatory bowel disease, microarrays, serology, recombinant antigens, R&D, former SERCA awardee) Lela Riley, PhD, ACLAM, Professor, N129 RADIL (Director of the RADIL, molecular biology, parvoviruses, murine norovirus, biosensors, resource centers, mutant swine, R&D) Earl Steffen, PhD, Assistant Professor, N126 RADIL (serology, microbiology, R&D) Pat Stewart, DVM, ACLAM, Assistant Director of Animal Resources, 1720 E. Campus Loop (lab animal medicine) 10. ANIMAL PERSONNEL TRAINING All research personnel working with animals must accomplish the required institutional training. The training module is available online and takes 20-30 minutes to complete. The URL for this Basic Training in Animal Care and Use is: https://research.missouri.edu/acqa_secure/animalCare/index.php. You will need a University Pawprint to take this course (contact Pat Parry to get this arranged if you do not have one). Contact Holly Rice (573-882-1746; riceh@missouri.edu) with questions about this training. 11. ACCESS PHOTOS OF PEOPLE The RADIL maintains a photo collection of its employees and the CMP postdocs. To access this page seehttps://internal-radil.missouri.edu/radil/radilphotos/photomenu.asp 12. TOURS 1) If you’d like a tour of the MU campus and Columbia, schedule with Dr. Franklin 2) If you’d like to tour the MU vet school, contact Kathy Seay in the Dean’s office (seayk@missouri.edu or 573-884-6435). Introduce yourself as an extern / elective block student of the Comparative Medicine Program. She will need a couple of days lead time to schedule with student ambassadors. 13. AVMA COMPETENCY/TECHNICAL PROCEDURES ASSESSMENT (MU ELECTIVE STUDENTS ONLY) 1) Participation of AVMA competency/technical procedures assessment is a requirement for this elective. A student who fails to complete this requirement will have their letter grade reduced by one letter. Students must complete and have approved 75% of the procedures on the list for this task to be considered completed. For some blocks, activities (e.g. IACUC meetings) may not be ongoing during the students elective. In these cases, the student will be excused from these activities. 14. CONTACT INFORMATION Adams, Veronica Bauer, Beth Besch-Williford, Cindy Bryda, Elizabeth Caraker, Susan Cook, Lydia Cowan, Bo Crim, Marcus Critser, John Dale, Bill Dixon, Lon Drake, Mike Ericsson, Aaron Farrar, Pat Franklin, Craig Gettys, Diana Gruenkemeyer, Jill Hamilton, Shari Jackson, Glenn Korte, Scott Lawrence, Janelle Lee, Hanni Linville, Mike Livingston, Bob Lopez, Franklin Manuel, Chris Mayfield, Rose Myles, Matt Neff, Sherrie O’Connor, Erin Parry, Pat Purdy, Greg Rice, Holly Riley, Lela Postdoc – OAR Faculty – RADIL Faculty – RADIL Faculty – RADIL Pathology – RADIL DVM/PhD program Tissue prep – RADIL Postdoc – Research/RADIL Faculty – RADIL Faculty – ACQA Faculty – OAR Postdoc – Research Postdoc – Research Faculty – OAR Faculty – RADIL Postdoc – Research/OAR Histology – RADIL Pathology – RADIL Postdoc – Research/OAR Faculty – OAR Repro service / Cryo - RADIL Postdoc – Research Faculty – OAR Faculty – RADIL Postdoc – Research/RADIL Postdoc – Research Program coordination - RADIL Faculty – RADIL Investigator Support – OAR Postdoc – Research/OAR Finances – RADIL Cell culture / virology - RADIL ACQA Faculty – RADIL adamsve@missouri.edu bauerbe@missouri.edu willifordc@missouri.edu brydae@missouri.edu carakersm@missouri.edu lcc550@missouri.edu cowanb@missouri.edu crimM@missouri.edu critserj@missouri.edu dalew@missouri.edu dixonl@missouri.edu Drakem@missouri.edu ericssona@missouri.edu farrarp@missouri.edu franklinc@missouri.edu gettysd@missouri.edu gruenkemeyerj@missouri.edu hamiltonsr@missouri.edu jacksongl@missouri.edu kortes@missouri.edu lawrenceja@missouri.edu leehan@missouri.edu linvilleml@missouri.edu livingstonr@missouri.edu lopezfr@missouri.edu manuelc@missouri.edu mayfieldro@missouri.edu mylesm@missouri.edu neffs@missouri.edu oconnore@missouri.edu parryp@missouri.edu purdyG@missouri.edu riceh@missouri.edu rileyl@missouri.edu Sharpe, Debbie Sittaramane, Vinoth Steffen, Earl Stewart, Pat Stoffel, Ryan Walters, Eric Weber Bettina Wisdom, Laurie Wolff, Sara PCR – RADIL Postdoc – RADIL Faculty – RADIL Faculty – OAR Postdoc – Research Faculty – RADIL/swine center Postdoc – Research Necropsy – RADIL ACQA sharpede@missouri.edu vks6f8@mizzou.edu steffene@missouri.edu stewartpat@missouri.edu stoffelrt@missouri.edu walterse@missouri.edu weberb@missouri.edu wisdoml@missouri.edu wolffsm@missouri.edu To send an email to all, cut and paste the following into the to line adamsve@missouri.edu; bauerbe@missouri.edu; willifordc@missouri.edu; brydae@missouri.edu; carakersm@missouri.edu; lcc550@missouri.edu; cowanb@missouri.edu; critserj@missouri.edu; dalew@missouri.edu; dixonl@missouri.edu; Drakem@missouri.edu; ericssona@missouri.edu; franklinc@missouri.edu; gettysd@missouri.edu; gruenkemeyerj@missouri.edu; hamiltonsr@missouri.edu; jacksongl@missouri.edu; kortes@missouri.edu; leehan@missouri.edu; linvilleml@missouri.edu; livingstonr@missouri.edu; livingstonr@missouri.edu; manuelc@missouri.edu; mayfieldro@missouri.edu; mylesm@missouri.edu; neffs@missouri.edu; oconnore@missouri.edu; parryp@missouri.edu; riceh@missouri.edu; rileyl@missouri.edu; sharpede@missouri.edu; steffene@missouri.edu; stewartpat@missouri.edu; stoffelrt@missouri.edu; weberb@missouri.edu; wisdoml@missouri.edu; wolffsm@missouri.edu; purdyG@missouri.edu; crimM@missouri.edu; lopezfr@missouri.edu; lawrenceja@missouri.edu; walterse@missouri.edu; adamsve@missouri.edu; farrarp@missouri.edu Post-Doc Phone List - February 13, 2016 Name 3+ years Bettina Weber Weberb@missouri.edu Chris Manuel manuelc@missouri.edu Mike Drake drakem@missouri.edu Aaron Ericsson ericssona@missouri.edu Hanni Lee leehan@missouri.edu Ryan Stoffel stoffelrt@missouri.edu 3rd year Diana Gettys gettysd@missouri.edu Erin O’Connor oconnore@missouri.edu Glenn A. Jackson jacksongl@missouri.edu Lydia Crystal Cook (Dual) Lcc550@missouri.edu Office Lab Home 884-7244 884-7244 573-239-3621 Pager Cell 573-239-6321 8146000 x 53708 VAH 884-4474 573-999-9559 882-9433 882-1019 882-3173 573-874-1390 441-3011 882-0541 882-0541 573-808-2689 808-7834 573-808-2689 884-4378 884-4738 397-9443 608-698-0699 882-2838 882-2838 397-9471 405-742-0768 882-7121 882-7121 397-9442 314-974-9764 882-3749 882-7748 817-3704 573-234-4674 314-971-3262 573-234-4674 884-9222 2nd year Marcus Crim crimM@missouri.edu Franklin Lopez lopezfr@missouri.edu Vinoth Sittaramane vks6f8@mizzou.edu 1st year 882-4774 979-229-4495 882-7089 787-457-2285 882-4774 573-529-3931 Veronica Adams adamsve@missouri.edu Other RADIL main line 882-7089 713-562-4161 OAR main line OAR Emergency 882-5983 8006690825 882-3111 884-7521 fax 884-4345 fax 441-4198