Dr Shujun Zhang Professor in Animal Genetics, Breeding and Reproduction Expertise Statement Teaching Duties Animal Reproduction for Undergraduate Biotechnology of Animal Reproduction, Animal Reproduction Theory for Master student Research progress for Animal Reproduction for PhD Student Research Interests Animal genetics and breeding of disease-resistance Regulating mechanism of animal reproduction Animal transgenic technology Professional Memberships Evaluating Expert of Wuhan Grant for Young Researchers Expert of Wuhan Evaluation Commission of Academic titles Vice-director of Reproduction Committee of China Dairy Cow Association Standing Committee Member of Chinese Association of Animal Reproduction Education & Working Experience Education Experience Ph.D: Sichuan Agricultural University, Sichuan, China 9/1998-7/2001 Research on Animal Molecular Genetics and Breeding of Reproduction Animal Molecular Genetics and Breeding of Meat Quality Master of Science: Sichuan Agricultural University, Sichuan, China 9/1988-7/1991: Research on Animal Genetics and Breeding Bachelor of Science: Huazhong Agricultural University, Wuhan, China 9/1984-7/1988: Major on Animal Husbandry Work Experience Professor and supervisor of PhD student: 9/2001-4/2004, 10/2005-Present Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education College of Animal Sciences and Technology Huazhong Agricultural University, China Research: Animal Molecular Genetics of Reproduction and Disease Fellowship: 24/07/07-24/07/08 for one year Cambridge University, Pathology Department, Human Molecular Genetics and Genomics, Cambridge, UK Research: Identification of Variation using microarrays in Pig Genes Potentially Influencing Response to Infection with PRRS Virus The fellowship from BBSRC of UK Academic Visiting Scholar: 15/04/2004-14/10/2005 for one and half years Cambridge University, Pathology Department, Human Molecular Genetics and Genomics, Cambridge, UK Research: the genetics of host responses to porcine respiratory and reproduction syndrome (PRRS), using microarray to study gene expression and genotyping. Senior research fellow: 9/1991-9/1998 Wuhan Institute of Animal Science and Technology, China Research: Animal Genetics and breeding of Reproduction and Meat Quality Director of Research, the Head of Animal Science Group Publications Published over 130 papers in academic journals, such as PNAS, BMC Microbiology, J Anim. Breed Genet. 1) Ao Zhou, Shu-jun Zhang*. Regulation of cell signaling and porcine reproductive and respiratory syndrome virus. Cellular Signalling, 24(5):973-80 2012. Doi:10.1016/ j.cellsig. 2012.01.004. (SCI: IF= 4.243 ) 2) J.J. Wu, J.S. Brickell, L.G. Yang, Z. Cheng, H.Q. Zhao, D.C. Wathes, S.J.Zhang*.Reproductive performance and survival of Chinese Holstein dairy cows in central Chi na,Animal Production Science, 2012. doi:10.1071/AN11146. (SCI: IF= 1.342 ) 3) Wei Wang, Jian Yang, Hui Liu, Dong Lu, Xiongfeng Chen, Zenon Zenonos, Lia Campos, Roland Rad, Ge Guo, Shujun Zhang, Allan Bradley and Pentao Liu. Rapid and Efficient Reprogramming of Somatic Cells to iPSCs by Rarg and Lrh-1. PNAS(Proceedings of the National Academy of Sciences of the United States of America), 108(45):18283-8. October 11, 2011. doi: 10.1073/pnas.1100893108, . (SCI: IF= 9.771 ) 4) Peter J I Ellis, Yong Yu, Shujun Zhang. Transcriptional dynamics of the sex chromosomes and the search for offspring sex specific antigens in sperm. Reproduction, 2011, 142: 609-619. doi: 10.1530/REP-11-0228. (SCI:IF=3.049) 5) S.J. Wang, W.J. Liu, C.A. Sargent, S.H. Zhao, H.B. Liu, X.D. Liu, C. Wang, G. H. Hua, L.G. Yang, N.A. Affara and S. J. Zhang*. Effects of the Polymorphisms of Mx1, BAT2 and CXCL12 Genes on Immunological Traits in Pigs. Molecular Biology Reports, 39(3):2417-27. 2011, DOI10:1007/s11033-011-0992-y .(SCI: IF=1.857) 6) S.J. Wang, W.J. Liu, L.G. Yang, C.A. Sargent, H.B. Liu, C. Wang, X.D. Liu, S.H. Zhao, N.A. Affara, A.X. Liang and S. J. Zhang* infectious disease. Molecular Biology Effects of FUT1 Gene mutation on resistance to Reports, 39(3):2805-10. 2011,DOI10 : 1007/s11033-011-1039-0. (SCI: IF=1.857) 7) Liu HB, Zhang RR, Ko SY, Oyajobi BQ, Papasian CJ, Deng HW, Zhang SJ, Zhao M*. Microtubule assembly affects bone mass by regulating both osteoblast and osteoclast functions, -Stathmin deficiency produces an osteopenic phenotype in mice. J Bone Miner Res. 26(9):2052-67. 2011 May 6.doi:10.1002/jbmr.419; PMID: 21557310. (SCI: IF=7.056) 8) Hui Liu, Wei Wang, Dong Lu, Su-Kit Chew, Song-Choon Lee, Juan Li, George S. Vassiliou, Tony Green, Allan Bradley, Shujun Zhang* and Pentao Liu. Stella-Cre Mice are Highly Efficient Cre Deleters. Genesis, 2011: 49(8):689-95. Genesis.doi: 10.1002/dvg.20741. (SCI: IF=2.266) 9) Liu XB, Liang AX, Feng XG, Guo AZ, Ke CY, Zhang SJ, Yang LG. Oral and intranasal administration of somatostatin DNA vaccine mediated by attenuated Salmonella Enterica Serovar Typhimurium to promote growth of piglets. Animal, 2011 ; 5 ( 8 ): 1231 - 1236. doi:10.1017/S1751731111000231. (SCI, IF=1.895) 10) C. Wang Q. Tong X.Z. Hu L.G.Yang X.Q. Zhong Y. Yu J.J. Wu W.J. Liu X. Li G.H. Hua H.Q. Zhao S.J. Zhang*.Identification of Complex Vertebral Malformation carriers in Holstein cattle in south China,Genetics and Molecular Research, Volume 10 Number 4, 2443-2448, 2011. (SCI, IF=1.735) . doi: 10.4238/2011 11) Jinfeng Yuan, Shujun Zhang*(first author), Osman Jaffer, Oriane Chausiaux, Rob Furlong,Carole. Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus, BMC Microbiology 2009,9:246. doi:10.1186/1471-2180-9-246.(SCI, IF=2.89) 12) S.J. Zhang*, O. Jafer, J.F. Yuan, H.C. Chen1, C. A. Sargent, B. Wu,R. Zhou, L.G. Yang, H. Liu, J.J. Wu, H.B. Liu, Q. Tong, Y. Yu1 and NA. Affara. Association analysis between pseudorabies antibody and five single nucleotide polymorphisms in pigs. Animal (2009), 3:10,1363–1367. doi:10.1017/S1751731109004856.(SCI, IF=1.461) 13) M. Yusuf, P. Musilova , S. Kubickova, J. Rubes, S. J. Zhang, N. A. Affara, C. A.Sargent, and D. K. Griffin. Mapping of 12 porcine fatness candidate genes in known fatness QTL based on human syntenies. Anim Genet, 2009 Aug;40(4):579-80 . (SCI, IF=2.64) 14) Osman Jafer, Shujun Zhang, Carole Sargent, Martha A Mellencamp, Gary Evans, Alan Mileham, Graham Plastow and Nabeel Affara1. Identification of SNPs in porcine genes expressed during Porcine Respiratory and Reproductive Syndrome Virus (PRRSv) infection. Anim Genet, 2009 Aug;40(4):580-2. (SCI, IF=2.64) 15) W. M. Li, Y. P. Feng, R. X. Zhao, Y. Z. Fan, N.A.Affara, J. J. Wu, J. Fang, Q Tong, C. Wang and S. J. Zhang* Sex Ratio Bias in Early-Death Embryos of Chicken Collected during the First Week of Incubation.POULTRY SCIENCE, 87 (11): 2231-2233 NOV 2008(SCI, IF=1.603) 16) J.J. Wu, W.M. Li, R.X. Zhao, J. Fang, C. Wang, X.L. Peng, X. Li, J.J. Xiong, Q Tong, L.G. Yang and S.J. Zhang*. The effects of the polymorphism in exon-3 of the FAS gene on he death of chicken embryos during the incubation period. Anim Genet, 2008, 39(5):558-60 (SCI, IF=2.64) 17) J. F. Yuan, M. Moaeen-ud-Din, Y. Z. Gong, X. L. Peng, L. G. Yang, Y. P. Feng, J. Liu, Ben. Hu, N. A. Affara, O. Jafer , and S. J. Zhang*. Identification of Mutations of Zona Pellucida Glycoprotein (ZP3) and its Association with Pig Reproductive Traits, J Anim Breed Genet. 2007 Jun;124(3):144-9 (SCI, IF=1.038) 18) J. F. Yuan, O. Jafer, N. A. Affara, Y. Z. Gong, L. G. Yang, J. Liu, M. Moaeen-ud-Dina1, W. M. Li and S. J. Zhang* Association of four new single-nucleotide polymorphisms in follicle-stimulating hormone receptor and zona pellucida glycoprotein with reproductive traits in pigs. Animal (2007), 1: 1249-1253 (SCI, IF=1.895) 19) Feng Y., Zhang S., Peng X., Yuan J., Yang Y., Zhan H. and Gong Y. Expression analysis of genes putatively involved in chicken gonadal development. Acta Biologica Hungarica, 2007, 58(2):163-172 Zhang S, Xiong Y, Den C. FSHR Gene Mutation and its Effect on Litter Size in Pigs. Asian-Australian Journal of Animal Sciences, 2004.2:179-82 (SCI F=0.857) Additional Information Chinese research projects: As PI for the 29 projects from Chinese government, currently presided for National Natural Science Foundation of China (NSFC) Ministry of education fund for returnee from oversea Doctoral Fund of Ministry of Education of China International Collaboration Projects from UK support: 1. 2008-2009 Identification of genetic markers associated with fertility and longevity traits in dairy cows, China-UK Innovation of science and technology ICUK Partnership Grant, 14.5 thousands pounds Shujun Zhang was the Chinese-side Director 2. 2009. 11 acquired 19 thousands pounds of funds to hold 《The first China-UK Joint Conference on Animal Production and Disease Control》 3. 2009-2010 Identification of genetic markers associated with fertility and longevity traits in dairy cows, China-UK Innovation of science and technology ICUK Proof of Concept Project Shujun Zhang was the Chinese-side Director, 90 thousands pounds 4. 2009-2011 Development of gene array technology to identify heath and Welfare traits in farm livestock. BBSRC China Partnering Award selected and sent one master and one PhD students and two undergraduate students to RVC to carry out the grant. Shujun Zhang was the Chinese-side Director. 35 thousands pounds 5、 2010-2014 Monitoring and controlling the incubation of hen eggs,European Union FP7 Framework Project a Marie Curie. Tong Qin to RVC to carry out the project of Training as a 4 year fully funded PhD student. International Collaboration Project from China: 6. 2010-2012 Identification of Genes and Marker Associated with Dairy Cow Reproduction using GWAS and Its Application . China-UK Key International Collaboration Projects Shujun Zhang is the director 7. 2010-2012 Identification of Genes and Marker Associated with longevity traits in dairy cows, Wuhan International Collaboration Project 201070934339 Shujun Zhang is the director 8. 2011-2013 Establish of China-UK joint laboratory of animal breeding and disease control technology research, Wuhan International Collaboration Project Huanchun Chen is the director 9. 2011-2015 Establish of China-UK joint laboratory of animal breeding and disease control technology research Huazhong Agricultural University Shujun Zhang is the director 10. 2011-2015 Hubei Province International Science and Technology Collaboration Base: International Science and Technology Collaboration Base for Animal Breeding and Disease Control Technology Internationalization education, academic exchange: 1. Huazhong Agricultural University awarded Professor Professor Dorothy Claire Wathes, Christopher Wathes, and Professor Colin Howard as guest professor 2. Professor Dorothy Claire Wathes, Professor Colin Howard, Dr ZhangRui Cheng, Dr Geoff Pollott gave lessons to undergraduate students, master students and doctoral students in Huazhong Agricultural University. 3. In November, 2009, we held the first China-UK Joint Meeting on Animal Production and Disease Control in HZAU, Wuhan, China. 4. In October, 2011, we held the second China-UK Joint Meeting on Animal Production and Disease Control in HZAU, Wuhan, China. 5. In April, 2010, we establish China-UK joint laboratory of animal breeding and disease control technology research Contact details Key Laboratory of Ministry of Education of Agricultural Animal Genetics, College of Animal Science and Technology Huazhong Agricultural University Phone: 86-27-87515340, 15071338061 Fax: 86-27-87515340 Email: sjxiaozhang@mail.hzau.edu.cn