RESEARCH DAY SCHEDULE for March 17 and 18, 2008. Harless Auditorium – Marshall Medical Center Disclosure: No Disclosures or Conflicts of interest are indicted for activity planners or speakers for this CME activity. Research Day Opening Lecture Guest Speaker: Gregory Alan Hale, M.D. Associate Professor, Department of Pediatrics University of Tennessee Memphis, Tennessee Monday, March 17, 2008, 6PM – Harless Auditorium, Medical Center “Transplantation and Cellular Therapies: Current Research and Future Opportunities Learning Objectives: 1. Recognize hematopoietic cell donor choices for patients requiring transplantation. 2. Name novel indications for hematopoietic cellular therapies currently being investigated. 3. Discuss characteristics that facilitate or impede clinical research in hematopoietic cell transplantation. 4. Describe cell populations currently being used in practice and clinical trials of hematopoietic cell transplantation. Lecture Content: This lecture will provide an overview of the current state of hematopoietic cell transplantation and therapies, describing outcomes for unrelated donor and mismatched donor transplantation. Specific cellular therapies such as mesenchymal cells, T-lymphocytes, and natural killer cells will be reviews with respect to improvements in transplant recipient outcomes. Novel disease treated by hematopoietic cellular therapies such as ischemic heart disease, limb ischemia, autoimmune diseases will be reviewed. Finally, the current state of clinical research and outcomes analysis will be reviewed. This talk will be an overview of novel therapies and future opportunities in the field of hematopoietic cellular therapies. Tuesday, March 18, 2008, 12:30PM, Harless Auditorium “An introduction to Hematopoietic Cell Transplantation” Learning Objectives: 1. Recognize common indications for treatment with hematopoietic cell transplantation. 2. Define the process for hematopoietic stem cell collection, patient and donor evaluation, and recipient transplantation. 3. Compare and contrast the available hematopoietice stem cell sources. Lecture Content: This lecture will define autologous and allogeneic transplantation, review the clinical indications and volumes for each, list the sources of hematopoietic stem scells available, describe the transplant process, report patient outcomes for certain transplant types and diagnoses, and identify future opportunities for improvements in these outcomes. This lecture will be an introductory talk, directed at those providing direct patient care, covering an educational level from medical students to attending physicians. March 18, 2008 Learning Objectives: By the end of these lectures the participant will be able to: 1. Compare different approaches to medical investigation. 2. Compare and contrast the importance of basic research and cellular mechanisms as it relates to human disease. 3. Discuss and review research related to current and future improvements in the clinical management of patients. 4. Interpret and analyze data for medical investigation to potentially determine the effectiveness towards improving patient care. ORAL Session (Page ___) I 1 2 3 4 5 Effects of Decreased SKI on Invasive Properties of Testicular Cancer Cells Prasanna Is There an Association Between Last Measured Santhanam A1C and NSTEMI in Diabetic Patients? Rocky Mountain Spotted Fever mimicking Fadi Alkhankan community-acquired pneumonia The Relationship of the Pseudomonas Aeruginosa F. Heath Algu Stress Response and Outer Membrane Damron Integrety A Study of Clinical Characteristics, Ultrasound Features and Cytology Results of Patients Abay Taddesse Undergoing Fine Needle Aspiration Biopsy of Thyroid Nodules at MU Endocrinology Clinic Amy Nash BREAK 6 7 8 9 10 POSTER SESSION I - ATRIUM ORAL Session (Page ___) II Peritoneal-seeded Struma Ovarii associated with Ayman Elkadry hyperthyroidism secondary to thyroid stimulating immunoglobulins Chromatin-Remodeling Proteins As Potential J. Adam Hall Regulators of Sublingual Gland Differentiation In Mouse The Use of Innovative Teaching Methods to Lucia I.Soltis Prepare Students For USMLE STEP 2 Blastomycosis Mimicking as Metastatic Breast Toni Pacioles Cancer Genetic Polymorphism of the CYP3A4 Gene May Lauren Waugh Contribute to Methadone-Related Deaths BREAK BOX LUNCH Gregory Hale An introduction to Hematopoietic Cell Guest Speaker Transplantation 8:30AM 8:42AM 8:54AM 9:06AM 9:18AM 9:4510:30am 10:30AM 10:42AM 10:54AM 11:06AM 11:18AM 11:45AM 12:30PM ORAL Session III 11 12 Waseem Ostwani Majd Alnas A Retrospective Study Comparing Beractant and Poractant Treatment in Very Low Birth Weight Infants With Respiratory Distress Syndrome Cardiac Embolization of Inferior Vena Cava Filters 1:15PM 1:27PM 13 Samer AbuSultaneh Plethysmography: Can It Be The New Allen’s Test? 1:39PM 14 Abdrhman Hamo A Brugada Syndrome Diagnosed After Sudden Cardiac Arrest 1:51PM BREAK POSTER SESSION II- ATRIUM 2:30PM 3:15PM 15 16 17 ORAL Session (Page ___) IV N-Acetyl-L-Cysteine Enhances All-Trans Retinoic Anne Silvis Acid Mediated Differentiation of SK-N-SH 3:15PM Neuroblastoma Cells Tracy A Report of a Rare “Slit Fracture” Through Two 3:27PM Hendershot Adjacent Cervical Vertebrae Interesting Case of post-traumatic small bowel Joshua O’Brien 3:39PM intussusceptions in a 4-year-old boy: a case report AWARDS PRESENTATION-Harless Auditorium #** PRESENTER 1 Yared Gebregiorgis Poster Presentations Session I, 9:45AM10:30AM- Atrium TITLE (Page ___) TIME* Coexistence of PTH and non-PTH related hypercalcemia in a 71 yrs old female patient 9:45AM-10:30AM 2 Hany Guirgis 3 Aaron Kaibas 4 Peter Di Martino Massive Pulmonary Embolism with right ventricular thrombosis in a patient with metastatic cancer 9:45AM-10:30AM Retrograde Arterial Flow (You’re Going The Wrong Way) 9:45AM-10:30AM Ventricular Fibrillation in a patient with osteogenesis imperfect and no risk 9:45AM-10:30AM 4:30PM 5 Marina Flaskas 6 John Tiano 7 Andrea Kellar 8 Abdullah Altayeh 9 Jay Lakhani 10 Fadi Alkhankan 11 Melissa Lester 12 Adam Ritchie 13 Syed Naveed Hussain 14 John Mason factors for cardiac disease including coronary artery disease or structural heart disease Acute Pulmonary Embolism in a patient with no significant risk factors for venous thromboembolism, A Case Report and Discussion of Diagnostic Modalities 9:45AM-10:30AM Diagnosis by Transespohageal Echocardiography of a Mural Thrombus in the Arch of the Aorta 9:45AM-10:30AM Massive Splenomegaly, Portal Vein Thrombosis, Thrombophilias, and Thrombocytosis in a High Risk Obstetrical Patient 9:45AM-10:30AM Smoking Related Interstitial Lung Disease 9:45AM-10:30AM Renal Atrophy as a Complication of Umbilical Arterial Catheterization 9:45AM-10:30AM Hemothorax as a complication of benign schwannoma 9:45AM-10:30AM Perival Alvular Prosthetic Valve Abscess in a Patient with Methicillin sensitive staphylococcus aurens bacteremia , A Case Report and Discussion of Diagnostic Modalities 9:45AM-10:30AM Fibromucular Dysplaisa with Bilateral Carotid and Vertebral involvement in a post partum patient: A Case Report 9:45AM-10:30AM Thyrotropin Secreting Pituitary Adenoma, A Rare Cause of Hyperthyroidism 9:45AM-10:30AM Right Atrial Mass 9:45AM-10:30AM 15 16 17 18 19 20 21 #** A Case of Bilateral Robert Cross Carotid and Subclavian Aneurysms Teaching the Art of Medicine: A Changing Aaron Lambert Portrait in Today's Medical Schools A short-term consumption of high fat diet affects Kan Huang endothelial nitric oxide synthase in lean Zucker rats Intracranial Subdural Hematoma Following Amy Hendrix Spinal Anesthesia in a Parturient Patient: A Case Study The Effect of Humidified Double Walled Incubators on Total Fluid Samer AbuRequirements and sultaneh Persistent Ductus Arteriosus in very low birth weight infants Neonatal Morbidity of Gina Jereza-Harris Delivery From 37 to 38 Weeks Gestation Paradoxical Pulmonary Abdullah Altayeh Embolsim PRESENTER 22 Syed Naveed Hussain 23 Abdrhman Hamo 24 Zaher Qassem 9:45AM-10:30AM 9:45AM-10:30AM 9:45AM-10:30AM 9:45AM-10:30AM 9:45AM-10:30AM 9:45AM-10:30AM 9:45AM-10:30AM Poster Presentations Session II, 2:30PM3:15PM- Atrium TITLE (Page ___) A Cowden Syndrome Patient with Papillary Thyroid Carcinoma In A Recurrent Multinodular Goiter 2:30PM Unusual case of MayThurner syndrome presenting with pulmonary embolism 2:30PM Anti-Synthetase Syndrome, Pulmonary Embolism (PE) and Interstitial Lung Disease (ILD)- A rare disorder with an unusual presentation 2:30PM TIME* 25 26 27 28 29 30 31 32 33 34 35 Resveratrol Protection of Marcus Terneus Cisplatin Mediated Oxidative Stress 2:30PM Epigenetic Modulation Through HSP90 Serves Jennifer Napper As A Mechanism of Induced Phenotypic Plasticity 2:30PM Identifying Phenotypic Differences in Myeloid Melinda Varney Progenitor Cell Frequency Among Inbred Mouse Strains 2:30PM Detecting Load In Pedal Extremities: Structure and Responses of Sense Bridget Keller Organs That Encode Forces In The Tarsi of Cockroaches 2:30PM The Utility of Chlamydia Screening at 34-36 Weeks Gestation in Ellie Hood Patients 25 years of Age and Younger, A Retrospective Study 2:30PM Characterization of Babies Discharged from Cabell Huntington Franklin Ross Hospital During the Baxter Calendar Year 2005 with the Diagnoses of Neonatal Abstinence Syndrome 2:30PM The Point Prevalence of Agenesis of the Corpus Tracy Hendershot Callosum at Two WV Academic Hospitals 2:30PM Eyad Hamoudeh Pending receipt of title 2:30PM Predictors of Fibrosis in Tae Hoon Lee Nonalcoholic Steatohepatitis 2:30PM Spontaneous Closure of Small and Medium Sized Jack Stines Isolated Secundum Atrial Septal Defects in Children 2:30PM Habitual Constipation in Waseem Ostwani Children: It’s All In The Family!! 2:30PM 36 37 38 Joshua Dillon Erick Willis Abdullah Altayeh In-Hospital Medication Errors In Children-A Two Year Retrospective Study Improvement in Extrauterine Growth Restriction in Very Low Birthweight Infants Primary Pulmonary Amyloidosis AWARDS PRESENTATIONHarless Auditorium 2:30PM 2:30PM 2:30PM 4:30 PM