Cell Division Biology Notes
Unit Outcomes: TLW compare and contrast the process and significance of meiosis and mitosis.
1. TLW relate the process of mitosis by sequencing the stage of mitosis as body cells are
formed.
2. TLW relate the process of meiosis to the formation of sex cells.
3. TLW compare and contrast the chromosome number in mitosis and meiosis.
Mitosis Lecture
I.
Why must cells divide?
II.
Vocabulary
a. Chromosome
b. Karyotype
III.
Goal of Mitosis
 Each cell goes through a regular life cycle.
Example: Human life cycle may be referred to as infancy, childhood, adolescence,
young adult, adult and senior. Major stages of a cell are Interphase, mitosis and
cytokinesis.
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IV.
Stages of Mitosis (IPMAT)
What it looks like inside:
Interphase



Diploid = 3
chromosome pairs
Vocabulary:
a. Sister Chromatids -
b. Centromere -
Prophase
Pro-metaphase – starts
moving to center



Metaphase

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Anaphase

Telophase



Cytokinesis
V.
Cell Cycle
Mitosis
G2
Cell Cycle
G1 – cell carries out normal
functions
G1
S – DNA is copied
G2 – cell carries out normal
functions
S
(DNA Synthesis)
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a. G1
b. S
c. G2
d. M (cytokinesis)
How does mitosis lead to cancer?
What is happening?
What causes it to occur?
Result:
Examples:
P53:
Brac1:
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Meiosis Lecture
I.
Meiosis
a. Diploid
b. Haploid
c. Tetrad
d. Gametes
(sex cells)
e. Human chromosome number:
II.
Stages of Meiosis
Interphase:
Cell is doing its job
DNA is copied
Organelles and materials replicated
(same as Mitosis)
Prophase 1:
Sister Chromatids appear as pairs
Spindle fiber begins to attach to centromere on sister chromatids
_________________________ can occur – leads to independent assortment (life is
a box of chocolates)
Metaphase 1:
_____________________________________ form a ______________________
Homologous chromosomes align at the equatorial plate
Pushed by spindle fibers to middle
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Anaphase 1:
Homologous pairs separate with ______________________________ remaining
together
Telophase 1:
each daughter contains only one chromosome of the
_______________________________________ (not a pair of chromosomses).
Prophase 2:
Sister chromatids pair up
Spindle fibers grow and attach to centromere
(same as mitosis)
Metaphase 2:
Sister chromatids line up at _______________________
Pushed there by spindle fibers
(same as mitosis)
Anaphase 2:
Centromeres divide and ___________________________migrate separately to each
pole.
(same as mitosis)
Telophase 2:
Total of _____________________________________ daughter cells instead of
two.
Daughter cells have _________________________________________of
chromosomes found in the original parent cell and with crossing over, are genetically
different
What are the differences between Mitosis and Meiosis?
Mitosis
Meiosis
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MEIOSIS I
MEIOSIS II
a. Products of meiosis in males?
b. Products of meiosis in females?
III. Timing in humans
c. Females
d. Males
e. Helpful saying
I don’t use “Mi-Toes-es” for making sperm or eggs!
Problems:
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