Central Line Maintenance Royal Hospital for Sick Children PICU Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 1 of 7 Issue Date: Contents 1. 2. 3. 4. 5. 6. 7. Background Appropriate hand hygiene Central line dressings Use of smartsites Transducer sets Review References Page Number(s) 2 3 4 4 5 6 6 1. Rationale To provide a standardised care pathway for maintenance of central lines. To provide educational material about the importance of reducing catheter-related bloodstream infections as part of our patient safety program. 2. Scope This guideline applies to the maintenance of all central lines in the paediatric intensive care unit. To be used in conjunction with the hospital guideline for central lines1. 3. Roles & Responsibilities All healthcare professionals involved in the care of patients with central lines should be aware of this guideline. 4. Evidence This guideline has been constructed after consultation with standard text books, a pubmed search (cather-related bloodstream infections, antisepsis, Chloraprep©, pressure transducers and infection), Scottish Patient Safety Program2 and local expert opinion. 1. Background Intravascular catheters are an essential part of modern intensive care practice. Unfortunately their use exposes patients to a number of infectious complications, especially nosocomial bacteraemia3. Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 2 of 7 Issue Date: Catheter-related bloodstream infections (CR-BSI) have a significant impact on patient morbidity, mortality and healthcare costs4. One of the main patient safety initiatives in intensive care medicine is reduction of CR-BSI. There are a number of ways in which we can reduce the CR-BSI incidence: 1. Standardised insertion technique, focusing on the ‘Central Line Bundle.’ This is covered in the ‘Central Line Insertion’ guideline and focuses on appropriate antisepsis and preparation and an insertion checklist to empower staff to stop the procedure if the sterile insertion technique is not followed correctly. 2. Standardised practice for central line maintenance, as outlined in this guideline. 3. Daily review of the need for central access and removing unnecessary lines as soon as possible to minimise the risk of infection. ‘Central line maintenance’ is an essential part of reducing CR-BSI. A study by Miller at al. specified that the main driver for additional reductions in paediatric CR-BSI relate to a ‘maintenance bundle.5’ Even with a careful and aseptic insertion technique, the central line provides a route of entry for bacteria. Contamination of central lines may occur by the following6: o Skin organisms at the insertion site enter the cutaneous tract along the surface of the central line with colonisation of the tip – this is the most common o Direct contamination by contact with contaminated hands, fluids or devices o Haematogenously seeding from other sites – less common o Contamination of infusate - rare Subsequent infections may be difficult to treat, may cause deterioration of an already unstable patient and may necessitate removal of the intravascular catheter7. Maintenance of the central line is as important as the insertion in regards to minimising CR-BSI. This guideline focuses on the following: Appropriate hand hygiene as per NHS GG&C hand hygiene guideline8 and sterile gloves of the staff member accessing the central line Close attention to central line dressings Use of SmartSites© on central lines Use of ChloraPrep© and Clinell© for antisepsis Changing of transducer sets every 72 hours In addition, the need for the central access should be reviewed on a daily basis at the ward round and removed if deemed appropriate. Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 3 of 7 Issue Date: 2. Appropriate Hand Hygiene Close attention to hand hygiene and wearing sterile gloves before handling or accessing central lines is vital. Clear guidance is given by Infection Control guidelines (above the sinks on ICU) on the correct handwashing technique. 3. Central Line Dressings Central line dressings should be clean, dry and secure. Dressings should be routinely changed every 7 days, or earlier if soiled or non-adherent. Dressings should be reviewed daily. When changing the dressing, the skin should be cleaned with ChloraPrep© and labelled with the date changed. Correct dressing Incorrect dressing 4. Use of SmartSites©& Bionectors© (refer to guideline) SmartSites© or Bionectors © should be used on all ports, but not between 3-way taps. They reduce infection rates in vascular access devices by providing closure to the catheter hub. Before accessing SmartSites© or Bionectors©, they should be cleaned with Clinell© wipes (alcoholic 2% chlorhexidine) for 30 seconds and allowed to dry for 30 seconds before use. The 30 second drying period is essential as that is when bacterial killing occurs. SmartSites© or Bionectors© on bolus ports should be changed on Wednesday and Sunday. They are only licensed for 200 activations, so to ensure that they are changed regularly, this will occur twice weekly. SmartSites©/Bionectors© on infusion ports should be changed on Sunday. Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 4 of 7 Issue Date: 5. Transducer Sets Patients requiring transducer monitoring are more likely to be colonised by nosocomial organisms and more vulnerable to infections3. Reported outbreaks of nosocomial bacteraemia have been reported from arterial infusions used for pressure monitoring from as early as the 1960s6. The following are important to reduce the risk of infection and are in keeping with the CDC 2011 Guidelines for the Prevention of Intravascular Catheter-Related Infections6: Change every 72 hours, except intracardiac lines (PA and LA lines). Replace other components of the system at the time the transducer is replaced SmartSite© or Bionector© between Lectrocath and 3-way taps (arterial and CVP). Minimise the number of manipulations of and entries into the pressure monitoring system. Do not administer dextrose-containing solutions or parenteral nutrition through pressure monitoring circuits. Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 5 of 7 Issue Date: 6. Review This guideline should be reviewed every two years from the date of approval. Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 6 of 7 Issue Date: 7. References 1. http://www.clinicalguidelines.scot.nhs.uk/YOR-DIV008%20Central%20Venous%20Access%20devices%20March%202 012.pdf (Accessed April 2012) 2. http://www.staffnet.ggc.scot.nhs.uk/Corporate%20Services/Clinical %20Governance/Key%20Information/Documents/SPSPP%20CVC% 20Insertion%20Bundle%20v0%201.doc (Accessed April 2012) 3. O’Grady N, Alexander M, Patchen Dellinger E, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weistein RA. ‘Guidelines for the Prevention of Intravascular Catheter Related Infections.’ Pediatrics. 2002;110;e51 4. Miller MR, Griswold Rice TB, Ridling D, ‘Decreasing PICU MACHRI’s Quality 125:206-13 M, Harris M, Yonokyan G, Huskins C, Moss M, Campbell D, Margolis P, Muething S, Brilli R. Catheter-Associated Bloodstream Infections: Transformation Efforts.’ Pediatrics. 2010; 5. Miller MR, Griswold M, Harris II JM, Yenokyan G, Huskins WC, Moss M, Rice TB, Ridling D, Campbell D, Margolis P, Muething S, Brilli RJ. ‘Decreasing PICU Catheter-Associated Bloodstream Infections: NACHRI’s Quality Transformation Efforts.’ Pediatrics. 2010; 125(2):206-213 6. O’Grady NP, Alexander M, Burns LA, Dellinger P, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph A, Rupp ME, Saint S, Healthcare Infection Control Practices Advisory Committee. ‘Guidelines for the Prevention of Intravascular Catheter-Related Infections, 2011.’ CDC, Department of Health & Human Services USA, 2011. 7. Raad II, Hanna HA. ‘Intravascular Catheter-Related Infections New Horizons and Recent Advances.’ Archives of Internal Medicine. 2002; 162:871-8 8. http://library.nhsggc.org.uk/media_Assets/Infection%20Control/27 .09.11%20-%20Hand%20Hygiene%20v2.pdf (Accessed April 2012) 9. Mermel LA, Maki DG. ‘Epidemic Bloodstream Infections From Haemodynamic Pressure Monitoring: Signs of the Times.’ Infection Control & Hospital Epidemiology. 1989;10(2): 47-53 Central Line Maintenance Author: Christina Harry Lesley Macfarlane, Spenceley Date of Review: Neil Version: Authorised by: Q-Pulse Ref: Page 7 of 7 Issue Date: