IDP – GMS #6064 (Advanced Tumor Biology): Spring-2015 Course director: Satya Narayan, Ph.D. Department of Anatomy and Cell Biology Basic Science Building, Room B1-016 PO Box 100235 1333 SW Center Drive Phone: 352-273-8163 FAX: 352-846-1248 Email: snarayan@ufl.edu Lecture schedule: 1. Date 3-23-15 Day Monday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Introduction to tumor development: Genetic basis of tumorigenesis Lecturer – Satya Narayan, Ph.D. (Email: snarayan@ufl.edu) Paper for discussion: TBA Student: 2. Date 3-25-15 Day Wednesday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Oncogene and Cancer Lecturer – Brian Law, Ph.D. (Email: bklaw@ufl.edu) Paper for discussion: TBA Student: 3. Date 3-30-15 Day Monday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Tumor suppressor genes and cancer Lecturer – Maria Zajac-Kaye, Ph.D. (Email: mzajackaye@ufl.edu) Paper for discussion: TBA Student: 4. Date 4-01-15 Day Wednesday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Cell cycle control and cancer Lecturer – Daiqing Liao, Ph.D. (Email: dliao@ufl.edu) Paper for discussion: TBA. Student: 1 5. Date 4-06-15 Day Monday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – DNA repair and cancer Lecturer – Satya Narayan, Ph.D. (snarayan@ufl.edu) Paper for discussion: TBA. Student: 6. Date 4-08-15 Day Wednesday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Gene regulation and cancer Lecturer – Silvia Tornaletti, Ph.D. (Email: silviat@ufl.edu) Paper for discussion: TBA Student: 7. Date 4-13-15 Day Monday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Molecular basis of invasion and metastasis Lecturer – Alexander Ishov, Ph.D. (Email: Ishov@ufl.edu) Paper for discussion: TBA Student: 8. Date 4-15-15 Day Wednesday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Apoptosis and cancer Lecturer – Stratford May, Jr., MD, Ph.D. (Email: smay@ufl.edu) Paper for discussion: TBA Student: 9. Date 4-20-15 Day Monday Time 9:00 AM-10:30 AM Room No. HPNP G-301A Lecture title – Structure-based designing of drugs for chemotherapeutic intervention of cancer Lecturer – Satya Narayan, Ph.D. (Email: snarayan@ufl.edu) Paper for discussion: TBA Student: 10. Date Day Time 4-22-15 Wednesday 9:00 AM-10:30 AM 2 Room No. HPNP G-301A Lecture title – Gene therapy approach in cancer management Lecturer – Arun Srivastava, Ph.D. (Email: aruns@peds.ufl.edu) Paper for discussion: TBA Student: Grading – 60% Oral Presentation and Group Discussion – A selected published paper on the related topic will be presented and discussed in the group. The presenter will be mostly responsible to defend the author’s point of view, but not limited to contribute his/her own thoughts and ideas on the topic. This format of study is designed to enhance student’s group discussion ability concluding with evaluation of individual knowledge acquisition. 40% Class Participation and Assignments - The assignment will include one short (4-page) scholarly papers on discussing a topic of his/her own choosing, which is covered in this course. The papers will consist of one page of specific aims and three pages of background and significance. It is expected that the student will identify an interesting question(s) in tumor biology, suggest a series of “aims” to address the selected question (appropriate in scope for a 4-year grant) and then justify both the question and the background and significance section. The purpose of this topic is to reinforce in the student the qualities required to become a logical thinker, critical evaluator, and skilled writer. This requires the ability to review the literature critically and to be able to integrate information into a format that is useful for self-education and for implanting information to peers. The papers can be submitted at any time prior to the last day of the course. The grading on oral presentation and assignments will be A-E. A minimum ‘C’ grade will be required for graduation. 3