MEDICINE AND PHARMACOLOGY: PHARMACOLOGY
Peer Reviewed Articles: (* designates articles with medical or graduate students or post-doctoral
fellows)
1. *Gilstrap LC, Little BB, Klein VR. Antibiotic use during pregnancy. Advances in Infectious
Disease. 1987;1:1-9.
2. *Little BB, Snell LM, Palmore MK, Gilstrap LC. Cocaine use in pregnant women in a large public
hospital. American Journal of Perinatology. 1988;5:206-207.
3. Little BB, Snell LM, Gilstrap LC. Methamphetamine abuse during pregnancy: outcome and infant
effects. Obstetrics and Gynecology. 1988;72:541-544.
4. *Little BB, Snell LM, Klein VR, Gilstrap LC: Cocaine abuse during pregnancy: Maternal and fetal
implications. Obstetrics and Gynecology. 1989;73:157-160.
5. Little BB, Gilstrap LC. Cardiovascular drugs during pregnancy. Clinical Obstetrics and
Gynecology. 1989;32:13-20.
6. *Little BB, Bawdon RE, Christmas JT, Sobhi S, Gilstrap LC. Pharmacokinetics of zidovudine
(AZT) during late pregnancy in Long Evans rats. American Journal of Obstetrics and Gynecology.
1989;161:732-734.
7. Little BB, Snell LM, Gilstrap LC, Gant NF , Rosenfeld CR. Alcohol abuse during pregnancy:
Changes in frequency in a large urban hospital. Obstetrics and Gynecology. 1989;74:547-550.
8. *Little BB, Snell LM, Gilstrap LC, Breckenridge JD, Knoll KA. Effects of T's and Blues abuse
during pregnancy on maternal and infant health status. American Journal of Perinatology.
1990;7:359-362.
9. Little BB, Snell LM, Gilstrap LC, Johnston WL: Patterns of substance abuse during pregnancy:
Implications for the mother and fetus. Southern Medical Journal. 1990;83:507-509 and 518.
10. *Little BB, Snell LM, Klein VR, Gilstrap LC, Knoll KA, Breckenridge JD. Maternal and fetal effects
of heroin addiction during pregnancy. Journal of Reproductive Medicine. 1990;35:159-162.
11. Friedman JM, Little BB, Brent RL, Cordero JF, Hanson JW, Shepard TH. Potential human
teratogenicity of frequently prescribed drugs. Obstetrics and Gynecology. 1990;75:594-599.
12. Leveno KL, Little BB, Cunningham FG. National impact of tocolytic therapy on low birth weight.
Obstetrics and Gynecology. 1990;76:12-15.
13. Little BB, Snell LM, Gilstrap LC, Rosenfeld CR, Gant NF. Failure to recognize fetal alcohol
syndrome in newborn infants. American Journal of Diseases in Children. 1990;44:1142-1146.
14. *Roe, DA, Little BB, Bawdon RE, Gilstrap LC. Metabolism of cocaine by human placentae:
Implications for fetal exposure. American Journal of Obstetrics and Gynecology. 1990;163: 713718.
15. *Harstad TH, Little BB, Bawdon RE, Sobhi S, Roe DA, Knoll KA. Embryocidal and teratogenic
effects of pentamidine isethionate administered to pregnant Sprague-Dawley rats. American
Journal of Obstetrics and Gynecology. 1990;163:912-916.
16. Little BB, Snell LM, Wendel GD, Gilstrap LC, Johnston WL, Gluck KL. Prevalence of HIV in
pregnant intravenous drug users in Dallas, Texas. Texas Medicine. 1991;87:81-83.
17. Little BB, Snell LM. Brain growth among fetuses exposed to cocaine in utero: Asymmetric growth
retardation. Obstetrics and Gynecology. 1991;77:361-364.
18. *Little BB, Harstad TH, Bawdon RE, Sobhi S, Roe DA, Knoll KA, Ghali FE. Pharmacokinetics of
pentamidine in late pregnant Sprague-Dawley rats. American Journal of Obstetrics and
Gynecology. 1991;164:927-930.
19. Maberry MC, Gilstrap LC, Bawdon RE, Little BB, Dax J. Anaerobic coverage for intraamniotic
infection: maternal and perinatal impact. American Journal of Perinatology. 1991;8:338-341.
20. *Little BB, Knoll KA, Ghali FE, Snell LM, Rosenfeld CR, Gant NF . Heroin abuse during
pregnancy: effects on perinatal outcome and early childhood growth. American Journal Human
Biology. 1991;3:463-468.
21. Little BB, Santos-Ramos R, Newell JF, Maberry MC. Megadose carbamazepine during
embryogenesis. Obstetrics and Gynecology. 1993;82:705-708.
22. *Ramin SM, Little BB, Trimmer KJ, Standard DI, Snell LM, Blakely CA, Garrett A.
Methamphetamine use during pregnancy in a large urban population. Journal of Maternal-Fetal
Medicine. 1994;3:101-103.
23. Hemsell DH, Hemsell PG, Nobles BJ, Johnson ER, Little BB, Heard MC. Cefazolin is inferior to
cefotetan for single-dose prophylaxis in women elective total abdominal hysterectomy. Clinical
Infectious Diseases. 1995;20:677-684.
24. *King TA, Perlman JM, Laptook AR , Rollins N, Jackson G, Little BB. Neurologic manifestations
of in utero cocaine exposure in near term and term infants. Pediatrics. 1995;96:259-264.
25. Little BB, Wilson GN, Teasley TC, Snell LM. Fetal alcohol syndrome: diagnosis, prevention,
prognosis, and management. Dallas Medical Journal. 1995;81:21-25.
26. *Stettler RW, Bohman VR, Little BB, Westfall KL, Sobhi S. Metabolism of cocaine by
cholinesterase during pregnancy: maternal and fetal activity. Journal of Maternal-Fetal Medicine.
1995;4:135-138.
27. *Little BB, Roe DA, Stettler RW, Bohman VR, Westfall KL, Sobhi S. A new placental enzyme in
the metabolism of cocaine: an in vitro animal model. American Journal of Obstetrics and
Gynecology. 1995;172:1441-1445.
28. *Little BB, Vanbeveren TT. Placental transfer of selected substances of abuse. Seminars in
Perinatology. Apr 1996;20(2):147-153.
29. Little BB, Jackson G, Wilson GN. Is there a cocaine syndrome? Teratology. 1996;54:145-149.
30. *Aguila-Nelson N., Little BB, Ho RY, Barnea A. Differential potencies of cocaine and its
metabolites and benzoylecgonine, in suppressing the functional expression of somatostatin and
neuropeptide Y producing neurons in cultures of fetal cortical cells. Biochemical Pharmacology.
1997;54:491-500.
31. Little BB. Immunosuppressant therapy during gestation. Seminars in Perinatology. 1997;21:143148.
32. *Yonkers KA, Little BB, March D. Lithium use during pregnancy: a controversy. CNS Drugs.
1998;9:261-269.
33. *Dobson A, Little BB, Scott LL. Prevention of herpes simplex virus infection and latency by
prophylactic treatment with acyclovir in a weanling mouse model. American Journal of Obstetrics
and Gynecology. 1998;179:527-532.
34. *Little BB, Snell LM, Trimmer KJ, Ramin SM, Ghali FE, Blakely CA, and A. Garret: Peripartum
cocaine use and adverse pregnancy outcome. American Journal of Human Biology. 1999;11:
598-602.
35. Little BB. Pharmacokinetics during pregnancy: evidence-based maternal dose formulation.
Obstetrics and Gynecology. 1999;93(51001) 858-868.
36. *VanBeveren TT, Little BB, Spence MJ. Effects of prenatal cocaine exposure and postnatal
environment on child development. American Journal of Human Biology. 2000;12:417-428.
37. *Little BB, Snell LM, Van Beveren TT, Crowell RB, Trayler S. Treatment of substance abuse
during pregnancy and infant outcome. American Journal of Perinatology. July 2003;20(5):255-62.
Book Chapters
1. Gilstrap LC, Little BB. Medication during pregnancy: maternal and embryofetal considerations.
In: High Risk Pregnancy: Management Options. James DK, Steer PJ, Weiner CP, B. Gonik, eds.
London, UK: W.B. Saunders; 1994:229-252.
2. Little BB. Chapter 36: medication during pregnancy. In: James DK, Steer PJ, Weiner CP, Gonik
B, eds. High Risk Pregnancy: Management Options. 3 rd Edition. London, U.K.: W.B. Saunders;
2006:742-771.
3. Little BB, Weideman R, Kelly K, Cryer B. Evidence-based medicine: data mining and
pharmacoepidemiology. In: Data Mining VII: Wessex Institute of Technology (Wessex, United
Kingdom). 2006;307-314.
Books Written
1. Gilstrap LC, Little BB. Drugs and Pregnancy 1st edition. New York, NY: Elsevier Press;
1992:472 pp.
2. Gilstrap LC, Little BB. Drugs and Pregnancy 2nd edition . New York, NY: Chapman and Hall:
New York , 523 pp. 1998 (1st , 2nd , and 3rd printings), Arnold Press: London, UK, 1999 (4th
printing), Oxford University Press: New York (1st , 2nd , 3rd and 4th printings).
3. Yonkers KA, Little BB. Treatment of Psychiatric Disorders During Pregnancy. London, UK:
Arnold Press and New York, NY: Oxford University Press: 2001; 266 pp.
4. Little BB. Drugs and Pregnancy. A Handbook 3rd edition. London, UK: Arnold Hodder Press and
New York, NY: Oxford University Press; November 2006: 372 pp.