Supplementary Table 5 (doc 224K)
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Supplementary Table 5: Genes specific for Legionella pneumophilastrain Paris with respect to strain Lens lpp0038 lpp0039 lpp0045 lpp0046 lpp0052 lpp0065 lpp0068 lpp0069 lpp0070 lpp0071 lpp0072 lpp0073 lpp0074 lpp0075 lpp0076 lpp0077 lpp0078 lpp0079 lpp0080 lpp0081 lpp0082 lpp0083 lpp0089 lpp0094 lpp0095 lpp0096 lpp0125 lpp0144 lpp0160 Similar to transposase (IS4 family) Similar to unknown proteins Similar to sterol desaturase Unknown Unknown HipB, Similar to transcriptional regulator HipB Unknown Unknown Unknown Similar to transposase (ISL3 family) Similar to phage-related integrase proteins Similar to phage-related proteins Similar to transcriptional regulator Similar to L.pneumophila LvrA protein Hypothetical gene Similar to cation/multidrug efflux pump Similar to membrane-fusion protein involved in transport Similar to outer membrane efflux protein Unknown Hypothetical gene Unknown Similar to transposase (IS5 family) Similar to conserved hypothetical protein Unknown Unknown Unknown Similar to transposase (IS4 family) Weakly similar to conserved hypothetical protein Similar to Wolinella succinogenes hypothetical protein 4.5 Transposon, IS and plasmid 5.2 From other organisms 2.4 Metabolism of lipids 6 No similarity 6 No similarity 3.5.2 Regulation 6 No similarity 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 4.4 Phage-related functions 4.4 Phage-related functions 3.5.2 Regulation 5.1 From Legionella 6 No similarity 1.2 Transport/binding proteins and lipoproteins 1.2 Transport/binding proteins and lipoproteins 1.2 Transport/binding proteins and lipoproteins 6 No similarity 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 5.2 From other organisms 5.2 From other organisms lpp0161 lpp0162 lpp0163 lpp0164 lpp0168 lpp0182 lpp0184 lpp0185 lpp0186 lpp0187 lpp0188 lpp0189 lpp0190 lpp0191 lpp0192 lpp0195 lpp0196 lpp0197 lpp0198 lpp0201 lpp0202 lpp0203 lpp0204 lpp0205 lpp0206 lpp0207 lpp0209 lpp0210 lpp0211 lpp0212 lpp0213 Similar to Wolinella succinogenes hypothetical protein Similar to Wolinella succinogenes hypothetical protein Similar to W. succinogenes hypothetical protein -RecB family exonuclease Similar to unknown proteins LvrC, similar to carbon storage regulator gene csrA Unknown Unknown some similarity with TraD protein Similar to unknown protein Similar to unknown proteins Similar to cytosine/adenosine deaminases Similar to putative membrane proteins Unknown Similar to transcriptional and prophage repressors Unknown Similar to hypothetical protein Similar to hypothetical protein Similar to adenine specific DNA methylase (Mod-related) similar to Type III restriction-modification enzyme, helicase subunit Similar to unknown proteins Ankyrin repeat protein Similar to unknown proteins Similar to conserved hypothetical proteins Unknown Similar to C-terminal part of phage integrase Similar to conserved hypothetical protein Similar to N-terminal part of sidC Similar to transposase (ISL3 family) Similar to unknown proteins, possibly interrupted by an IS element Hypothetical gene Unknown 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 3.5.2 Regulation 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmids 5.2 From other organisms 5.2 From other organisms 2.3 Metabolism of nucleotides and nucleic acids 5.2 From other organisms 6 No similarity 3.5.2 Regulation 6 No similarity 5.2 From other organisms 5.2 From other organisms 3.2 DNA restriction/modification and repair 3.2 DNA restriction/modification and repair 5.2 From other organisms 6 No similarity 5.2 From other organisms 5.2 From other organisms 6 No similarity 4.4 Phage-related functions 5.2 From other organisms 5.1 From Legionella 4.5 Transposons, IS and plasmid 5.2 From other organisms 6 No similarity 6 No similarity lpp0234 lpp0241 lpp0251 lpp0256 lpp0257 lpp0258 lpp0287 lpp0289 lpp0290 lpp0291 lpp0292 lpp0293 lpp0294 lpp0295 lpp0296 lpp0297 lpp0298 lpp0303 lpp0321 lpp0330 lpp0331 lpp0336 lpp0337 lpp0338 lpp0356 lpp0412 lpp0432 lpp0439 lpp0456 lpp0543 lpp0576 Unknown Unknown Unknown Unknown Similar to chitin-binding protein CbpD Unknown Similar to amino acid transporters Hypothetical gene Similar to unknown protein Similar to 3-oxacyl-(acyl-carrier-protein) reductase Similar to proline/betaine transporter ProP Similar to conserved hypothetical protein CyoA, cytochrome o ubiquinol oxidase subunit II CyoB, cytochrome o ubiquinol oxidase subunit I CyoC, Cytochrome o ubiquinol oxidase subunit III cyoC CyoD, Cytochrome o ubiquinol oxidase subunit IV Hypothetical gene Unknown Similar to N-terminal part of eukaryotic RNA-binding protein precursor Similar to transposase (IS4 family) Similar to conserved hypothetical protein Unknown Unknown Unknown Protein with ankyrin motif RpmD, rpmD, 50S ribosomal subunit protein L30 Putative lipopeptide Similar to choline dehydrogenase (N-terminal part) Unknown RpmG, 50S ribosomal subunit protein L33 Unknown 6 No similarity 6 No similarity 6 No similarity 6 No similarity 2.1.1 Specific pathways 6 No similarity 1.2 Transport/binding proteins and lipoproteins 6 No similarity 5.2 From other organisms 2.4 Metabolism of lipids 1.2 Transport/binding proteins and lipoproteins 5.2 From other organisms 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 6 No similarity 6 No similarity 4.6 Miscellaneous 4.5 Transposon, IS and plasmid 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 6 No similarity 3.7.1 Ribosomal proteins 1.2 Transport/binding proteins and lipoproteins 5.2 From other organisms 6 No similarity 3.7.1 Ribosomal proteins 6. No similarity lpp0582 lpp0583 lpp0587 lpp0588 lpp0589 lpp0673 lpp0716 lpp0717 lpp0769 lpp0770 lpp0771 lpp0772 lpp0773 lpp0774 lpp0775 lpp0777 lpp0778 lpp0779 lpp0829a lpp0829b lpp0829c lpp0830 lpp0835 lpp0851 lpp0859 lpp0881 lpp0882 lpp0983 lpp1006 lpp1007 lpp1035 Unknown Unknown Weakly similar to C.burnetii hypothetical protein Similar to P.aeruginosa probable fosfomycin resistance protein Similar to aminoglycoside 6 -N-acetyltransferase Unknown Similar to transposase (IS4 family) Similar to unknown proteins Similar to putative integrase Similar to transposase, partial Similar to transposase (IS5 family) Similar to transposase (IS5 family) Similar to transposase, partial Similar to tranposase, partial Similar to transposase Similar to tranposase Hypothetical gene Repeats in the N-terminal domain, similar to autotransporter Unknown Similar to central part of Legionella hypothetical protein Similar to C-terminal part of Legionella hypothetical protein Unknown Unknown Unknown Unknown Similar to transposase (IS4 family) Similar to unknown proteins Hypothetical gene Unknown Similar to other proteins Similar to transposase (ISL3 family) 6. No similarity 6. No similarity 5.2 From other organisms 4.2 Detoxification 4.2 Detoxification 6 No similarity 4.5 Transposon, IS and plasmid 5.2 From other organisms 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 6 No similarity 4.6 Miscellaneous 6 No similarity 5.1 From Legionella 5.1 From Legionella 5.1 From Legionella 5.1 From Legionella 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 5.2 From other organisms 6 No similarity 6 No similarity 5.2 From other organisms 4.5 Transposon, IS and plasmid lpp1041 lpp1050 lpp1051 lpp1052 lpp1053 lpp1054 lpp1072 lpp1073 lpp1074 lpp1075 lpp1077 lpp1078 lpp1079 lpp1080 lpp1081 lpp1089 lpp1090 lpp1097 lpp1098 lpp1100 lpp1110 lpp1122 lpp1130 lpp1144 lpp1216 lpp1217 lpp1218 lpp1219 lpp1220 lpp1221 lpp1253 Hypothetical gene Unknown Similar to unknown proteins Similar to unknown protein Unknown Unknown Unknown Similar to PilL protein Similar to carbon storage regulator Similar to Legionella LvrB protein Similar to phage repressor Similar to DNA modification methylase Unknown Similar to very-short-patch-repair endonuclease vsr Unknown Unknown Similar to methyltransferase Similar to transposase (IS5 family) Similar to transposase (IS5 family) Ankyrin repeat protein hypothetical protein Unknown Unknown Hypothetical protein, similar to endonuclease Hypothetical gene Unknown Similar to unknown protein Similar to thiocyanate hydrolase gamma subunit Simimlar to thiocyanate hydrolase alpha subunit Similar to thiocyanate hydrolase beta subunit Unknown 6 No similarity 6 No similarity 5.2 From other organisms 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 1.8 pili and other cell surface structures 3.5.2 Regulation 5.1 From Legionella 4.4 Phage related functions 3.2 DNA restriction/modification and repair 6 No similarity 3.2 DNA restriction/modification and repair 6 No similarity 6 No similarity 2.1.1 Specific pathways 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 6. No similarity 6 No similarity 6 No similarity 6 No similarity 3.2 DNA restriction/modification and repair 6 No similarity 6 No similarity 5.2 From other organisms 4.2 Detoxification 4.2 Detoxification 4.2 Detoxification 6 No similarity lpp1308 lpp1309 lpp1330 lpp1403 lpp1404 lpp1405 lpp1407 lpp1447 lpp1492 lpp1557 lpp1558 lpp1559 lpp1560 lpp1561 lpp1562 lpp1563 lpp1564 lpp1565 lpp1566 lpp1573 lpp1576 lpp1577 lpp1599 lpp1600 lpp1601 lpp1602 lpp1603 lpp1615 lpp1625 lpp1640 lpp1682 Unknown SidG protein, substrate of the Dot/Icm system Similar to hypothetical protein Similar to transcriptional regulator, LuxR family Unknown Similar to oxidoreductase Unknown Some similarity with eukaryotic proteins Similar to rubredoxin protein Unknown Similar to transposase (ISNCY family) Unknown Unknown Unknown Similar to transposase Similar to transposase (IS21 family) Similar to transposase (IS21 family) Similar to transposase (ISL3 family) Similar to transposase (ISL3 family) Similar to MutT/nudix family protein Similar to acetyltransferase, GNAT family Similar to hypothetical proteins Similar to conserved hypothetical protein Similar to 3-beta hydroxysteroid dehydrogenase/isomerase Similar to 3-oxoacyl-[acyl-carrier-protein] synthase III Similar to glycosyl transferase Unknown Some similarities with L. pneumophila SidE protein Unknown Unknown Unknown 6 No similarity 4.6 Miscellaneous 5.2 From other organisms 3.5.2 Regulation 6 No similarity 2.1.1 Specific pathways 6 No similarity 5.2 From other organisms 1.4 Membrane bioenergetics 6 No similarity 4.5 Transposon, IS and plasmid 6 No similarity 5.1 From Legionella 5.1 From Legionella 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 3.2 DNA restriction/modification and repair 2.1.1 Specific pathways 5.2 From other organisms 5.2 From other organisms 2.4 Metabolism of lipids 2.4 Metabolism of lipids 1.1 Cell wall - outer membrane 6 No similarity 5.1 From Legionella 6. No similarity 6. No similarity 6. No similarity lpp1800 lpp1812 lpp1813 lpp1822 lpp1823 lpp1824 lpp1851 lpp1852 lpp1862 lpp1868 lpp1870 lpp1877 lpp1878 lpp1890 lpp1895 lpp1904 lpp1905 lpp1906 lpp1908 lpp1910 lpp1912 lpp1928 lpp1929 lpp1940 lpp1942 lpp1944 lpp1945 lpp1947 lpp1956 lpp2037 lpp2039 Unknown Similar to conserved hypothetical protein Similar to transposase (IS4 family) Unknown Unknown Some similarity with eukaryotic proteins Similar to transposase (IS4 family) Similar to conserved hypothetical protein Unknown Unknown Similar to transposase (IS5 family) Unknown Similar to conserved hypothetical protein Similar to type IV pilin PilA Similar to hypothetical protein Unknown Ankyrin repeat protein Similar to N-terminal part of putative transposase (IS91 family) Unknown Conserved hypothetical protein Unknown Unknown Unknown Some similarity with eukaryotic proteins Unknown Similar to unknown protein Similar to transposase (IS4 family) Unknown Unknown Similar to transposase (ISL3 family) Unknown 6 No similarity 5.2 From other organisms 4.5 Transposon, IS and plasmid 6 No similarity 5.1 From Legionella 5.2 From other organisms 4.5 Transposon, IS and plasmid 5.2 From other organisms 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 6 No similarity 5.2 From other organisms 1.8 pili and other cell surface structure 5.2 From other organisms 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 6. No similarity 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 5.2 From other organisms 6 No similarity 5.2 From other organisms 4.5 Transposon, IS and plasmid 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 6 No similarity lpp2040 lpp2044 lpp2045 lpp2046 lpp2047 lpp2051 lpp2052 lpp2055 lpp2056 lpp2057 lpp2059 lpp2085 lpp2109 lpp2110 lpp2111 lpp2112 lpp2113 lpp2114 lpp2115 lpp2116 lpp2117 lpp2118 lpp2119 lpp2120 lpp2121 lpp2122 lpp2123 lpp2124 lpp2125 lpp2131 lpp2132 Similar to transposase (ISL3 family) Unknown Similar to amidase Similar to transposase (IS5 family) Unknown Similar to conserved hypothetical protein C-terminal part similar to transposase (IS4 family) Similar to conserved hypothetical protein Similar to transposase (IS5 family) Unknown Unknown Similar to conserved hypothetical proteins Some similarity with acetyltransferase Similar to adenosylhomocysteinase Unknown Unknown Unknown Unknown Unknown Similar to transcriptional regulator, sinR family Similar to bacteriophage protein similar to phage protein Unknown Similar to conserved hypothetical protein Unknown Unknown Similar to integrase/recombinase proteins Unknown Unknown Similar to peptide synthase Similar to two component sensor histidine kinase 4.5 Transposon, IS and plasmid 6 No similarity 2.2 Metabolism of amino acids and related molecules 4.5 Transposon, IS and plasmid 6 No similarity 5.2 From other organisms 4.5 Transposon, IS and plasmid 5.2 From other organisms 4.5 Transposon, IS and plasmid 6. No Similarity 6 No similarity 5.2 From other organisms 2.1.1 Specific pathways 2.3 Metabolism of nucleotides and nucleic acids 6 No similarity 6 No similarity 6 No similarity 6 No similarity 6 No similarity 3.5.2 Regulation 4.4 Phage-related functions 4.4 Phage-related functions 6 No similarity 5.2 From other organisms 6 No similarity 6 No similarity 4.4 Phage-related functions 6 No similarity 6 No similarity 4.6 Miscellaneous 1.3 Sensors-signal transduction lpp2139 lpp2147 lpp2168 lpp2179 lpp2192 lpp2245a lpp2245b lpp2311 lpp2312 lpp2313 lpp2314 lpp2315 lpp2316 lpp2317 lpp2318 lpp2319 lpp2327 lpp2328 lpp2329 lpp2330 lpp2331 lpp2332 lpp2333 lpp2334 lpp2335 lpp2336 lpp2337 lpp2338 lpp2339 lpp2340 lpp2341 Some similarity with eukaryotic proteins Unknown Some similarity with eukaryotic protein Similar to outer membrane protein Unknown Similar to transposase (IS4 family) Similar to transposase (IS4 family) Similar to transposase Similar to integrase Unknown Similar to L.pneumophila proline/betaine transport protein CitA (TphA) Similar to acetyltransferase Similar to hydrolase Putative transcriptional regulator Unknown Unknown Unknown Similar to ATP synthase beta chain Similar to ATP synthase epsilon chain (atpC) Similar to putative ATP synthase subunit Similar to ATP synthase A chain Similar to ATP synthase C chain Similar to ATP synthase B chain Similar to ATP synthase alpha chain Similar to ATP synthase gamma chain Unknown Similar to NADH oxidoreductase similar to unknown protein similar to putative cytochrome c family protein. Predicted membrane protein Predicted membrane protein, similar to hypothetical protein 6 No similarity 6 No similarity 5.2 From other organisms 1.1 Cell wall - outer membrane 6 No similarity 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.4 Phage-related functions 6 No similarity 1.2 Transport/binding proteins and lipoproteins 2.1.1 Specific pathways 2.1.1 Specific pathways 3.5.2 Regulation 6. No Similarity 6 No similarity 6 No similarity 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 1.4 Membrane bioenergetics 6 No similarity 1.4 Membrane bioenergetics 5.2 From other organisms 1.4 Membrane bioenergetics 6 No similarity 5.2 From other organisms lpp2342 lpp2343 lpp2344 lpp2346 lpp2347 lpp2348 lpp2349 lpp2350 lpp2354 lpp2355 lpp2357 lpp2358 lpp2359 lpp2360 lpp2361 lpp2362 lpp2363 lpp2364 lpp2365 lpp2366 lpp2367 lpp2368 lpp2369 lpp2374 lpp2375 lpp2376 lpp2377 lpp2378 lpp2379 lpp2380 lpp2381 Similar to unknown protein Unknown GdhA, Similar to glutamate dehydrogenase Predicted transmembrane protein Unknown Unknown Unknown CecA, Chemiosmotic efflux system C protein A Similar to outer membrane lipoprotein Regulatory protein (GGDEF domain) Unknown Similar to ribose-phosphate pyrophosphokinase Similar to thymidine/pyrimidine-nucleoside phosphorylase Similar to metallo-beta-lactamase superfamily proteins CebA CebB, Chemiosmotic efflux system B protein B CebC, Chemiosmotic efflux system B protein C CtpA, similar to cation transport ATPase Hypothetical gene Hypothetical gene Unknown Unknown CadA1, similar to cadmium-transporting ATPase (C-terminal part) Similar to unknown protein Similar to Legionella pneumophila putative phage repressor, PrpA Similar to Legionella vir region protein LvrA Similar to Legionella vir region protein LvrB Similar to Legionella vir region protein LvrC Similar to other proteins Unknown Similar to hypothetical protein 5.2 From other organisms 6 No similarity 2.2 Metabolism of amino acids and related molecules 5.2 From other organisms 5.1 From Legionella 5.1 From Legionella 6 No similarity 1.2 Transport/binding protein and lipoproteins 1.1 Cell wall - outer membrane 1.3 Sensors-signal transduction 6 No similarity 2.3 Metabolism of nucleotides and nucleic acids 2.3 Metabolism of nucleotides and nucleic acids 4.2 Detoxification 1.2 Transport/binding proteins and lipoproteins 1.2 Transport/binding proteins and lipoproteins 1.2 Transport/binding proteins and lipoproteins 1.2 Transport/binding proteins and lipoproteins 6 No similarity 6 No similarity 5.1 From Legionella 5.2 From other organisms 4.2 Detoxification 5.2 From other organisms 4.4 Phage-related functions 5.1 From Legionella 5.1 From Legionella 5.1 From Legionella 5.2 From other organisms 6 No similarity 5.2 From other organisms lpp2382 lpp2383 lpp2384 lpp2385 lpp2386 lpp2387 lpp2388 lpp2389 lpp2390 lpp2391 lpp2393 lpp2394 lpp2395 lpp2396 lpp2397 lpp2399 lpp2400 lpp2401 lpp2402 lpp2403 lpp2404 lpp2405 lpp2406 lpp2407 lpp2408 lpp2409 lpp2410 lpp2411 lpp2412 lpp2413 lpp2414 Similar to hypothetical protein similar to unknown protein Unknown Unknown Unknown Unknown Putative secreted protein Similar to conserved hypothetical protein, putative secreted protein Similar to conserved hypothetical protein Similar to conserved hypothetical protein, putative secreted protein Similar to conserved hypothetical protein Similar to conserved hypothetical protein Similar to conserved hypothetical protein Unknown Hypothetical gene Unknown Hypothetical gene Unknown Similar to transposase (ISL3 family) Unknown Weakly similar to integrase Similar to cobalt-nickel resistance system protein Unknown Similar to antirestriction protein Similar to conserved hypothetical protein Similar to hypothetical protein Similar to transposase (ISL3 family) Similar to transposase (ISL3 family) - partial Unknown Weakly similar to serine/threonine protein kinase Unknown 5.2 From other organisms 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 6 No similarity 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 6 No similarity 6. No similarity 4.5 Transposon, IS and plasmid 6 No similarity 4.5 Transposon, IS and plasmids 1.2 Transport/binding proteins and lipoproteins 6 No similarity 3.2 DNA restriction/modification and repair 5.2 From other organisms 5.2 From other organisms 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 6 No similarity 3.8 Protein modification 6 No similarity lpp2415 lpp2416 lpp2418 lpp2420 lpp2421 lpp2422 lpp2423 lpp2424 lpp2425 lpp2427 lpp2428 lpp2430 lpp2431 lpp2432 lpp2433 lpp2434 lpp2435 lpp2436 lpp2437 lpp2438 lpp2439 lpp2440 lpp2441 lpp2442 lpp2455 lpp2456 lpp2471 lpp2473 lpp2474 lpp2484 lpp2486 Similar to unknown proteins Similar to transposase - partial Unknown Hypothetical gene Similar to transposase Similar to unknown protein Similar to unknown protein Unknown Unknown Hypothetical gene Unknown Unknown Similar to conserved hypothetical protein Similar to hypothetical protein Similar to transporters Unknown Similar to conserved hypothetical protein Unknown Similar to hypothetical protein Hypothetical gene Similar to multidrug resistance proteins Unknown Similar to transcriptional regulator, LysR family Unknown Unknown Hypothetical gene Unknown Similar to oxidoreductase Unknown Unknown Some similarity with eukaryotic proteins, contains a F-box domain 5.2 From other organisms 4.5 Transposon, IS and plasmid 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 5.2 From other organisms 5.2 From other organisms 6. No Similarity 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 5.2 From other organisms 5.2 From other organisms 1.2 Transport/binding proteins and lipoproteins 6 No similarity 5.2 From other organisms 6 No similarity 5.2 From other organisms 6 No similarity 1.2 Transport/binding proteins and lipoproteins 6 No similarity 3.5.2 Regulation 6 No similarity 6 No similarity 6 No similarity 6 No similarity 2.1.1 Specific pathways 6 No similarity 6 No similarity 6 No similarity lpp2490 lpp2492 lpp2494 lpp2495 lpp2496 lpp2497 lpp2498 lpp2508 lpp2557 lpp2587 lpp2603 lpp2613 lpp2614 lpp2615 lpp2620 lpp2621 lpp2636 lpp2779 lpp2780 lpp2859 lpp2860 lpp2861 lpp2862 lpp2863 lpp2864 lpp2879 lpp2880 lpp2883 lpp2884 lpp2885 lpp2886 Unknown Unknown Similar to malonate decarboxylase, beta subunit Similar to malonate decarboxylase, gamma subunit Similar to phosphoribosyl-dephospho-CoA transferase Similar to 2-(5 -triphosphoribosyl)-3 -dephosphocoenzyme-A synthase Similar to malonyl-CoA acyl-carrier-protein transacylase Similar to hypothetical proteins Similar to hypothetical Inosine-5 -monophosphate dehydrogenase Unknown Similar to conserved hypothetical protein Hypothetical gene Hypothetical gene Unknown Unknown Similar to permeases of the drug/metabolite transporter (DMT) superfamily Unknown Similar to NADH-dependent flavin oxidoreductase (Oye family) Similar to transcriptional regulator, ArsR family Similar to conserved hypothetical protein Similar to dihydrodipicolinate synthase Similar to hypothetical protein Similar to transcriptional regulator Unknown similar to resolvase (partial) Similar to efflux protein similar to unknown protein SidH, substrate of the L. pneumophila Dot/Icm system, C_terminal part Similar to transposase (IS21 family) Similar to transposase (IS21 family) SidH, substrates of the L. pneumophila Dot/Icm system, N_terminal part 6 No similarity 6 No similarity 2.1.1 Specific pathways 2.1.1 Specific pathways 3.8 Protein modification 2.1.1 Specific pathways 2.1.1 Specific pathways 5.2 From other organisms 2.3 Metabolism of nucleotides and nucleic acids 6 No similarity 5.2 From other organisms 6 No similarity 6 No similarity 6 No similarity 6 No similarity 1.2 Transport/binding proteins and lipoproteins 6 No similarity 1.4 Membrane bioenergetics 3.5.2 Regulation 5.2 From other organisms 2.2 Metabolism of amino acids and related molecules 5.2 From other organisms 3.5.2 Regulation 6 No similarity 4.5 Transposon, IS and plasmid 1.2 Transport/binding proteins and lipoproteins 5.2 From other organisms 5.2 From other organisms 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 5.2 From other organisms lpp2887 lpp2895 lpp2896 lpp2954 lpp2955 lpp2956 lpp2957 lpp2967 lpp2968 lpp2978 lpp2983 lpp2984 lpp2986 lpp2987 lpp3006 lpp3007 lpp3008 lpp3009 lpp3010 lpp3011 lpp3012 lpp3016 lpp3017 lpp3018 lpp3019 lpp3020 lpp3045 lpp3070 lpp3077 plpp0001 plpp0002 Conserved ubiquitin conjugation factor E4 family domain (U-box) 5.2 From other organisms Similar to transposase (IS4 family) 4.5 Transposon, IS and plasmid Similar to conserved hypothetical protein 5.2 From other organisms Unknown 6 No similarity Unknown 6 No similarity Similar to acetyltransferases 2.1.1 Specific pathways Hypothetical gene 6 No similarity Unknown 6 No similarity Unknown 6 No similarity Similar to hypothetical protein 5.2 From other organisms Weakly similar to acetyltransferases 2.1.1 Specific pathways Weakly similar to conserved hypothetical protein 5.2 From other organisms Similar to acetyltransferase 2.1.1 Specific pathways Unknown 6 No similarity Similar to unknown protein 5.2 From other organisms Similar to hypothetical protein 5.2 From other organisms Unknown 6 No similarity Unknown 6 No similarity Similar to unknown protein 5.2 From other organisms Unknown 6 No similarity Similar to lipid A biosynthesis lauroyl acyltransferase 2.4 Metabolism of lipids LpxA, acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase 1.1 Cell wall - outer membrane Unknown 6 No similarity Similar to glycosyltransferase proteins 1.1 Cell wall - outer membrane Similar to methyltransferase 2.1.1 Specific pathways Similar to glycosyltransferase 1.1 Cell wall - outer membrane Hypothetical gene 5.2 From other organisms Unknown 6 No similarity RpmH, 50S ribosomal protein L34 3.7.1 Ribosomal proteins ParB, highly similar to partition protein ParB 3.4 DNA packaging and segregation Highly similar to partition protein SopA/ParA 3.4 DNA packaging and segregation plpp0003 plpp0004 plpp0005 plpp0008 plpp0015 plpp0016 plpp0017 plpp0018 plpp0019 plpp0020 plpp0021 plpp0022 plpp0023 plpp0024 plpp0025 plpp0026 plpp0027 plpp0028 plpp0029 plpp0030 plpp0031 plpp0032 plpp0033 plpp0034 plpp0035 plpp0036 plpp0037 plpp0038 plpp0039 plpp0040 plpp0041 Similar to hypothetical replication protein RepB Similar to hypothetical replicative protein RepA Similar to unknown proteins Unknown Unknown Weakly similar to carbon storage regulator CsrA Similar to E.coli TraT complement resistance protein Unknown Unknown Similar to transposase Similar to plasmid DNA replication protein similar to fimbrial protein precursor (Pilin) Weakly similar to conjugative transfer protein TraL Weakly similar to conjugative transfer protein TraE Weakly similar to conjugative transfer protein TraK Weakly similar to conjugative transfer protein TraB Hypothetical gene Weakly similar to conjugative transfer protein TraC Weakly similar to TrbI protein Weakly similar to conjugative transfer protein TraW Similar to conjugative transfer protein TraU Weakly similar to conjugative transfer protein TrbC Similar to putative conjugative transfer protein TraN Similar to putative conjugative transfer protein TraF Weakly similar to putative conjugative transfer protein TrbB Similar to conjugative transfer protein TraH Similar to sex pilus assembly and mating pair protein TraG Highly similar to conjugative transfer protein TraD Similar to conjugative transfer protein TraI Unknown Unknown 3.1 DNA replication 3.1 DNA replication 5.2 From other organisms 6. No similarity 6. No similarity 3.5.2 Regulation 4.5 Transposon, IS and plasmid 6 No similarity 6 No similarity 4.5 Transposon, IS and plasmid 3.1 DNA replication 1.8 pili and other cell surface structures 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 6 No similarity 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 6 No similarity 6 No similarity plpp0042 plpp0043 plpp0044 plpp0045 plpp0046 plpp0047 plpp0048 plpp0049 plpp0050 plpp0051 plpp0052 plpp0053 plpp0054 plpp0055 plpp0056 plpp0057 plpp0058 plpp0059 plpp0060 plpp0061 plpp0062 plpp0063 plpp0064 plpp0065 plpp0068 plpp0071 plpp0072 plpp0074 plpp0078 plpp0079 plpp0080 Unknown 6 No similarity Unknown 6 No similarity Unknown 6 No similarity Unknown 6 No similarity Unknown 6 No similarity Similar to putative anti restriction protein KlcA 3.2 DNA restriction/modification and repair Unknown 6 No similarity Similar to abortive infection bacteriophage resistance protein 4.4 Phage-related functions Similar to eukaryotic hypersensitive-induced response protein 5.2 From other organisms Similar to transposase (Tn3 family) 4.5 Transposon, IS and plasmid Similar to resolvase TnpR 3.3 DNA recombination Similar to conserved hypothetical protein 5.2 From other organisms Similar to ABC transporter (ATP-binding protein) 1.2 Transport/binding proteins and lipoproteins Similar to unknown proteins 5.2 From other organisms Unknown 6 No similarity Unknown 6. No similarity Unknown 6 No similarity Unknown 6 No similarity Hypothetical gene 6 No similarity Unknown 6 No similarity Unknown 6 No similarity Unknown 6 No similarity Unknown 6. No Similarity Weakly similar to conserved hypothetical protein 5.2 From other organisms Weakly similar to Legionella longbeachae spectinomycin 3 adenylyltransferase 5.1 From Legionella Similar to conserved hypothetical protein 5.2 From other organisms Similar to hypothetical protein 5.2 From other organisms Penicilin binding protein domain 1.1 Cell wall - outer membrane Hypothetical polysaccharide deacetylase-related, fusion protein 2.1.1 Specific pathways Similar to conserved hypothetical protein 5.2 From other organisms Similar to unknown protein 5.2 From other organisms plpp0081 plpp0082 plpp0083 plpp0084 plpp0085 plpp0086 plpp0087 plpp0088 plpp0089 plpp0090 plpp0091 plpp0092 plpp0093 plpp0094 plpp0095 plpp0096 plpp0097 plpp0098 plpp0099 plpp0100 plpp0101 plpp0102 plpp0103 plpp0104 plpp0105 plpp0106 plpp0107 plpp0108 plpp0109 plpp0110 plpp0111 Similar to dihydrofolate reductase and methyltransferase Similar to acetyltransferase, GNAT family Similar to hypothetical protein Similar to pyridoxamine 5 -phosphate oxidase Similar to unknown protein Hypothetical gene Weakly similar to alpha/beta hydrolase fold family protein Similar to transcriptional regulator Weakly similar to stability protein StbE Weakly similar to stability protein StbD Unknown Highly similar to spectinomycin 3 adenylyltransferase Highly similar to Legionella longbeachae unknown protein Highly similar to Legionella longbeachae unknown protein Unknown similar to unknown protein LrpR, Highly similar to L. longbeachae transcriptional regulatory protein Highly similar to L. longbeachae protein, ankyrin repeat containing protein lskS, Highly similar to L.longbeachae sensor histidine kinase protein Similar to hypothetical protein Unknown Conserved hypothetical protein Unknown Similar to hypothetical transcriptional regulator Conserved hypothetical protein Similar to hypothetical protein Weakly similar to probable transcriptional regulator Weakly similar to DNA alkylation repair enzyme Similar to hypothetical protein C-terminal part similar to acetyltransferase Weakly similar to lysE family transporter protein 2.5 Metabolism of coenzymes and prosthetic groups 2.1.1 Specific pathways 5.2 From other organisms 2.5 Metabolism of coenzymes and prosthetic groups 5.2 From other organisms 6 No similarity 2.1.1 Specific pathways 3.5.2 Regulation 4.5 Transposon, IS and plasmid 4.5 Transposon, IS and plasmid 6 No similarity 4.2 Detoxification 5.1 From Legionella 5.1 From Legionella 6 No similarity 5.2 From other organisms 3.5.2 Regulation 5.1 From Legionella 1.3 Sensors-signal transduction 5.2 From other organisms 6 No similarity 5.2 From other organisms 6 No similarity 3.5.2 Regulation 5.2 From other organisms 5.2 From other organisms 3.5.2 Regulation 3.2 DNA restriction/modification and repair 5.2 From other organisms 2.1.1 Specific pathways 1.2 Transport/binding proteins and lipoproteins plpp0112 Similar to acetyltransferase protein plpp0113 Similar to N-terminal part of hypothetical protein plpp0114 Similar to esterase plpp0115 Similar to shikimate kinase (AroK) plpp0116 Similar to aminoglycoside 3 -phosphotransferase plpp0117 Unknown plpp0118 Putative adenine-specific DNA methylase plpp0119 Weakly similar to acetyltransferase plpp0120 Unknown plpp0121 Weakly similar to acetyltransferase plpp0122 Similar to unknown protein plpp0123 Similar to unknown protein plpp0124 Bifunctional protein, similar to acetyl transferase and to methyl transferase plpp0125 similar to acetyltransferase, GNAT family plpp0126 Similar to conserved hypothetical protein plpp0127 Similar to acetyltransferase (C-terminal part) plpp0128 Unknown plpp0129 Some similarity with transcriptional regulator, MerR family plpp0130 Unknown plpp0131 Similar to alanyl tRNA synthetase plpp0132 Similar to hypothetical protein plpp0133 Unknown plpp0134 Weakly similar to transcriptional regulator plpp0135 Similar to conserved hypothetical protein plpp0136 Weakly similar to acetyltransferase plpp0137 C-terminal part similar to acetyltransferase plpp0138 Weakly similar to DNA topology modulation protein plpp0139 Weakly similar to regulatory protein recX plpp0140 Similar to integrase proteins plpp0141a Similar to N-terminal part of ATP-dependent DNA helicase recG plpp0141b Similar to ATP-dependent DNA helicase RecG(C-terminal part) 2.1.1 Specific pathways 5.2 From other organisms 4.1 Adaptation to atypical conditions 2.2 Metabolism of amino acids and related molecules 4.2 Detoxification 6 No similarity 3.2 DNA restriction/modification and repair 2.1.1 Specific pathways 5.1 From Legionella 2.1.1 Specific pathways 5.2 From other organisms 5.2 From other organisms 4.6 Miscellaneous 2.1.1 Specific pathways 5.2 From other organisms 4.6 Miscellaneous 6 No similarity 3.5.2 Regulation 6 No similarity 3.7.2 Aminoacyl-tRNA synthetases 5.2 From other organisms 6 No similarity 3.5.2 Regulation 5.2 From other organisms 2.1.1 Specific pathways 2.1.1 Specific pathways 3.4 DNA packaging and segregation 3.3 DNA recombination 4.5 Transposon, IS and plasmid 3.3 DNA recombination 3.3 DNA recombination