Revised: XY 2012 CONFIDENTIAL Ref.:………… CONFIDENTIALITY AGREEMENT This AGREEMENT, made and effective XX/YY/ZZZZ is entered into by and between IRCCS Istituto Nazionale Tumori Fondazione “Senatore G. Pascale”, located at Napoli, Via Mariano Semmola 80131 (“INT-PASCALE”) and Department WWWW (or company) KKKK, located at ...................................(“................................”) WHEREAS, INT-PASCALE has developed or has control over know-how in the field of oncology and in the identification of new potential targets for the therapy of cancer and wishes to exchange information with “............................” for the purpose of entering into a research and collaboration agreement WHEREAS, “...................”. has established capabilities and know–how in the field of oncology and is pursuing the development of new potential therapies of cancer WHEREAS the parties recognize that during and in connection with discussions between the parties there may be disclosure of certain confidential, proprietary, trade secret or like undisclosed information belonging to the parties or their associates (e.g., scientists and consultants), such disclosure being intended solely to assist the parties in their discussions with one another. In consideration of the premises and mutual covenants contained herein, the parties hereto agree as follows: 1. All information that a disclosing party believes to be confidential, proprietary, trade secret or like undisclosed information, including without limitation any biological materials, technical data or specifications, testing methods, research and development activities shall be provided in tangible, written or other permanent visual form (such as, for example, a physical prototype, physical sample, photograph, video tape, or sound recording) and clearly and appropriately labeled as confidential or proprietary at the time of delivery to the receiving party. Disclosures made orally shall be treated as confidential, provided that the disclosing party indicates the confidential nature of such disclosure at the time of making. 2. "CONFIDENTIAL INFORMATION" is defined as any information disclosed by one party to the other, which is identified by the disclosing party to be confidential or proprietary at the time of disclosure in accordance with the procedures set forth in Paragraph 1. However, CONFIDENTIAL INFORMATION shall not include any information which the receiving party proves that it: a) Is already known to the receiving party at the time of disclosure; or b) Is easily available to the public or becomes publicly known through no wrongful act of the receiving party; or c) Is received by the receiving party from a third-party who had a legal right to provide it; or d) Is developed independently of knowledge of CONFIDENTIAL INFORMATION received by the receiving party from the disclosing party as shown by respective documentation; e) Must be disclosed to governmental agencies. CDA Standard 1/3 Revised: XY 2012 CONFIDENTIAL Ref.:………… 3. With respect to CONFIDENTIAL INFORMATION, unless expressly authorized by the disclosing party in writing, which refers by name and date to this Agreement, the receiving party shall retain all CONFIDENTIAL INFORMATION separately and in confidence for a period of four (4) years from the date of the last transfer of CONFIDENTIAL INFORMATION under this Agreement, shall not disclose such CONFIDENTIAL INFORMATION to any third-party during said time period, and shall not use the CONFIDENTIAL INFORMATION for the benefit of any third-party. The obligation to return and/or destroy CONFIDENTIAL INFORMATION as agreed in Subsection 4. below shall survive termination of this Agreement. 4. Within thirty (30) days following a written request, the receiving party shall return or destroy all writings, models and the like supplied by the disclosing party except that one copy of same may be retained for legal purposes only. 5. The receiving party agrees to exercise the same care and safeguards with respect to CONFIDENTIAL INFORMATION disclosed by the disclosing party as used to maintain the confidentiality of its own information of like character, but in no event less than a reasonable degree of care. Neither party may assign or transfer this Agreement without the prior written consent of the other party, except that a party may assign this Agreement to a person or entity that acquires all or substantially all of its business or assets to which the CONFIDENTIAL INFORMATION primarily relates. 6. The parties agree that nothing herein shall obligate a party to disclose information by virtue of this Agreement. However, the parties recognize that from time to time one party may wish to disclose information to the other party that is of a character considered to be so highly proprietary and sensitive that additional restrictions on use and/or disclosure are necessary before such information can be disclosed. In such event, if mutually desired, the parties will negotiate a separate agreement governing the disclosure of such information. 7. If a receiving party is required by any governmental agency, court or other quasi-judicial or regulatory body to provide CONFIDENTIAL INFORMATION received under this Agreement, the receiving party shall not be liable for such disclosure provided that the receiving party, as promptly as reasonably possible, gives notice to the disclosing party of the requirement in order that the disclosing party may contest the requirement to provide such information. 8. Nothing contained herein shall be construed, either expressly or implicitly, to grant to the receiving party any rights to technology or license under any patent, copyright or trademark now or hereinafter in existence except for the limited purposes set forth herein. 9. In the event the parties make a later contract or agreement concerning anything covered by this Agreement, this Agreement shall continue to remain in full force and effect unless specifically stated to the contrary in such later contract. CDA Standard 2/3 Revised: XY 2012 CONFIDENTIAL Ref.:………… 10. The parties represent and warrant that they are entitled or authorized to communicate all CONFIDENTIAL INFORMATION disclosed by them to the receiving party. They will consult with their third party contacts prior to disclosing any confidential information that may belong to such third party contacts. 11. This Agreement constitutes the complete understanding between the parties of each party's obligations to the other party relating to the CONFIDENTIAL INFORMATION. This Agreement can be modified only by a written document executed by an authorized representative of the parties that refers to this Agreement and includes a copy of this Agreement as an attachment. 12. This Agreement shall be interpreted and applied in accordance with Italian law. Any dispute, controversy or claim arising out of or relating to this agreement, or subsequent amendments relating thereto, including any dispute as to the valid conclusion, binding effect, interpretation, performance, breach, termination or invalidity thereof, whether in contract or tort or other field of law (hereinafter referred to as "the Dispute"), shall be submitted to mediation or (if mediation is not successful with sixty (60) days after commencement of such proceedings) expedited arbitration in accordance with the WIPO’s Rules for Mediation and Expedited Arbitration in effect on the date of commencement of the proceedings. The provisions of this Agreement shall be several. Invalidity or unenforceability of one provision shall not affect any other provision of this Agreement. In lieu of the invalid or unenforceable provision a reasonable provision shall be deemed to be effective which shall achieve the original intention of the invalid or unenforceable provision. IN WITNESS THEREOF, each of the parties has caused this Agreement to be executed by a duly authorized representative on the dates entered herein below, and said representatives hereby warrant that they have been duly authorized to sign this Agreement on behalf of their respective parties. COMPANY By: _________________________ INT-PASCALE By: _________________________ Name: ____________________ Name: Dott. Tonino Pedicini Title: __________________ Title: General Manager CDA Standard 3/3