Tired of Suffering from Airborne Allergies? Airborne allergens can be classified as perennial or seasonal. Perennial allergens would include those things such as internal mold spores, dust and dust mites, animal dander and specific chemicals (cleaning agents and certain powders). If your allergy symptoms last more than two hours per day for more than nine months this would be classified as a perennial allergy. Seasonal allergies would include tree pollen, grass pollen, hay fever, fungal spores and weed pollen. Of the weed pollens, ragweed and goldenrod are among the most common offenders. If you suffer from allergies you may spend several months in spring, fall or even yearround with red, itchy, watery eyes, runny nose, sneezing, sinus headache, congestion or with asthmatic symptoms that make breathing a chore. Someone with airborne allergies suffers from an over-reactive immune system, which over responds to relative harmless substances such as pollen, mold, spores, or animal dander. An antibody called immunoglobulin E (IgE) binds to the offending allergen at one end and to the mast cells that line the respiratory tract at the other end. The mast cells burst open releasing histamine, interleukins and other inflammatory compounds. Many of the symptoms of airborne allergies are caused by the release of histamine and not by the allergen itself. Because of this histamine is the target of poplar drugs that are use to treat allergies. Histamine released by mast cells causes blood vessels to dilate and become leaky, promoting swelling and triggering runny noses, watery eyes, scratchy throats, and other annoying symptoms. Histamine also stimulates the secretion of large amounts of mucus and constricts the bronchioles, making it hard to breathe. Twenty percent of Americans periodically suffer with these symptoms, so it’s no wonder that allergy drugs are a multibillion dollar business. Allergy drugs like Benadryl, Allegra, and Claritin don’t prevent mast cells from releasing histamine; they simply block histamine receptors on other cells. As a result of the release of the histamine secondary side effects like congestion and asthmatic symptoms must be addressed by other drugs. Unfortunately, these allergy drugs have many side effects like: drowsiness or sleeplessness, dry mouth and fatigue. Unfortunately, these drugs do nothing to address the cause of allergies. Luckily, there are natural substances like those found in Natural–Hist that go beyond symptom relief to actually lighten the allergic response and promote overall health. Quercetin Quercetin’s effect on allergies is unmatched by other natural substances. Quercetin inhibits the release of histamine from mast cells, thereby preventing the allergic response and the secondary effects of congestion and asthmatic symptoms. Quercetin also inhibits leukotrienes which cause airway constriction. In addition, quercetin is a powerful antioxidant that mops up free radicals generated by an allergic reaction. Unfortunately, the absorption of quercetin is poor. Luckily, this can be altered with the concomitant administration of bromelain. Bromelain Bromelain, derived from the stem of the pineapple plant, can enhance the absorption of quercetin. An added benefit included with bromelain is its ability to block inflammatory pathways fibrin and kinin. These compounds are responsible for tissue swelling, nasal congestion and sinus pain. Bromelain has also been shown to decrease the viscosity of mucus in the lungs. Stinging Nettles In 1990 a double-blind, placebo-controlled study was done to assess the use of stinging nettle leaf for allergic rhinitis (hay fever like symptoms). After one week those taking stinging nettles noticed a much greater improvement in symptoms than those who were given the placebo. Recent research may explain the mechanism of action for stinging nettles due to its ability to block the formation of inflammatory chemicals (lipoxygenase and cyclooxygenase). N-Acetyl-Cysteine (NAC) Another antioxidant that gets high ranking for its ability to relieve allergies is n-acetylcysteine (NAC). NAC may be one of the best expectorant/mucolytic agents. As a disulfide reducing agent NAC can decrease the viscosity of mucus providing a mucoregulating action. NAC has been used quite frequently in an assortment of lung conditions including COPD, bronchitis and asthma. NAC is also gaining interest as an antioxidant that acts by itself and as a “recharger” of the body’s own glutathione stores. Vitamin C Vitamin C is a well-studied therapy for allergies as well as asthma. In fact, if taken when symptoms first arise, buffered vitamin C (4000mg) can stop an asthma attack or allergic reaction in its tracks. High-dose vitamin C can also reduce blood histamine levels dramatically when taken daily. Vitamin C itself is considered a natural antihistamine by preventing the secretion of histamine and clearing existing histamine from the bloodstream. Fifty million Americans suffer from inhalant allergies and as many as thirty five million Americans from hay fever. If you are one of the unfortunate suffers you could benefit from an all natural anti-histamine formula like Natural D-Hist. Otherwise, prepare to be miserable and buy stock in Kleenex, because you’ll need it! These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.