INTRODUCTION TO GENETICS BIOL 2050 H-A; FRSC 2050 H-A Course Outline Fall Semester 2012 Department of Biology, Trent University, Peterborough, ON Instructors: Dr Laura Finnegan DNA B108.14 laurafinnegan@trentu.ca Phone: 705-748-1011 ext 7130 Dr. Janet Yee CSB E110 jyee@trentu.ca Office Hours: Finnegan: Wednesdays 10-12 or by appointment; Yee: TBA Teaching Assistants: TBA Departmental Secretary: Sandra Sisson, DNA D102 Email: ssisson@trenut.ca Phone: 705-748-1011 ext 7424 Laboratory Coodinator: Smolly Coulson , DNA D219 Email: scoulson@trentu.ca Phone: 705-748-1011 ext 7927 Course Description: This course will provide an overview of introductory genetics by covering a variety of topics that include Mendelian inheritance, meiosis and mitosis, chromosome structure, transcription, translation, mutation, population genetics, evolutionary genetics, and some of the applications of genetics in society. Please consult Blackboard regularly for course material and announcements. Required Text: Genetic Essentials: Concepts & Connections 1st edition (2010) by Benjamin Pierce. WH Freeman, New York; ~$115.00 There is a very helpful, free Web site to accompany the book at http://whfreeman.com/pierceessentials1e. This site is provided FREE with the text from W.H. Freeman and includes valuable Animations/Podcasts, Weblinks and Classic Experiments. Available as a CourseSmart eBook at: http://www.coursesmart.com/9781429252393 for $59.95 (USD) for 360 days. The e-book version of Genetics Essentials includes activities, simulations, exercises – all integrated with an electronic version of the text. You can even bookmark and highlight as you would with a paper book. Lectures September 11 – December 5, 2012 Monday 4 – 4:50 pm; Location: OCA101.2 Wednesday 9– 9:50 am; Location: SC137 Attendance at lectures is highly recommended. Attending lectures will help with key concepts and focus areas and will allow you to participating in any class discussion that occurs. Labs September 17 – December 3, 2011 (Every other week) Mondays 9 – 11:50 am; DNA D103/105 Mondays 1 – 3:50 pm; DNA D103/105 Thursday 9 – 11.50am; DNA B113 Attendance at all laboratories is mandatory. Laboratory assignments are due at the end of each laboratory period. See or e-mail Sue White-Sobey (swhitesobey@trentu.ca) if you have not already signed up for a section. Ensure you ONLY ATTEND the lab section that you are signed up for Holidays: Thanksgiving: Monday October 8, 2012 Reading week: Monday October 22 – Friday October 26, 2012 Course Evaluation: Laboratories: 25% (5 labs each worth 5% - due at the end of each lab period) Short Essay: 15% (2-3 pages, double-spaced, (500 – 750 words): 15% Exam 1: 30% (In class on Monday, October 29, 4-6 pm, covers everything up to Thanksgiving) Exam 2: 30% TBA during Christmas exam period, covers everything after Thanksgiving Course feedback: 1% bonus Course Policies Penalties: Lab assignments are due at the end of each lab period. Lab assignments will not be accepted late and a mark of zero will be awarded if assignments are not handed in (Exceptions may be made for valid reasons (i.e. serious illness) if acceptable documentation (i.e. a medical doctor’s note) is provided). Please ensure you sign the lab attendance sheet before leaving the lab. The essay assignment is due by 5pm October 29th. Essays received up to 24 hours late (i.e. before 5pm Oct 30th) will be deducted 10% of the possible total grade for the assignment. Essays received after that time will be awarded a mark of zero (again exceptions may be made as previously outlined). Contact Preference: The best way to initially contact us is by e-mail. If required, we will meet you for appointments to discuss matters further. For e-mails received between Monday-Thursday, we will make every effort to respond within 24 hours. For those inquiries received on Fridays, we will reply by the following Monday. Please include your course number (BIOL/FRSC 2050) in the subject of your e-mail or the e-mail may not be answered. Remember that class discussion boards are also available on WebC. Academic Integrity Academic dishonesty, which includes plagiarism and cheating, is an extremely serious academic offence and carries penalties varying from a 0 grade on an assignment to expulsion from the University. Definitions, penalties, and procedures for dealing with plagiarism and cheating are set out in Trent University’s Academic Integrity Policy. You have a responsibility to educate yourself – unfamiliarity with the policy is not an excuse. You are strongly encouraged to visit Trent’s Academic Integrity website to learn more – www.trentu.ca/academicintegrity. Access to Instruction It is Trent University’s intent to create an inclusive learning environment. If a student has a disability and/or health consideration and feels that he/she may need accommodations to succeed in this course, the student should contact the Disability Services Office (BH Suite 109, 748-1281, disabilityservices@trentu.ca) as soon as possible. Complete text can be found under Access to Instruction in the Academic Calendar. Please see the Trent University academic calendar for University Diary dates, Academic Information and Regulations, and University and departmental degree requirements. Also ensure that you are aware of deadlines dates for withdrawal from the course without penalty. Lab cycle Date Day WebCT file Readings Sept. 10 Mon. Introduction & Mitosis/Meiosis Ch 1 and 2 No Lab Ch 3 (39-58) I Lab 1: Mitosis & Meiosis Ch 3 (59-61) Ch 4(69-84) II “ I Lab 2: Mendelian Genetics II " 12 Wed. 17 Mon. 19 Wed. 24 Mon. 26 Wed. Oct. 01 Mon. 03 Wed. “ Mendelian Genetics “ Pedigree Analysis & Sex Linkage “ Extension of the Basics Chromosome Variation 15 Mon. — Population & Evolutionary Genetics *Lab 3 assigned " 17 Wed. Review 08 Mon. 10 Wed. 22 - 26 Oct. 29 Lab (Mon.) Ch 4 Ch 7 Thanksgiving Ch 17 Reading week Mon. 31 Wed. Nov. 05 Mon. Test 1 DNA and RNA structures DNA replication No Labs Ch 8 Ch 9 07 Wed. " Ch 9 12 Mon. Transcription Ch10 14 Wed. Translation Ch 11 19 Mon. Gene Expression Ch 12 21 Wed. Gene Mutations Ch 13 I Lab 4: Working with DNA sequences II " I Lab 5: Phylogenetic Inheritance Ch 15 26 Mon. Cancer Genetics II " Ch 14 28 Wed. Biotechnology Dec. 03 Mon. " 05 Wed. Review *Lab 3 is a virtual lab which will be assigned after class on Wed 10th. If you need help with it come to the lab on Monday 15th. It is due Wed 17th at 9am in class.