DONOR SELECTION
TYPES OF BLOOD DONORS
• Voluntary unremunerated
• Replacement
• Directed
• Autologous
• Apheresis
DONOR SELECTION
This is the first and most important step in the safety of the blood supply!
GUIDELINES
 Protect the health of the donor
No harm to the donor
 Protect the health of the recipient
Minimizing risk of transfusion transmitted infections and other adverse risk
factors
DONATIONS
 Date of last donation
 Reasons for previous deferrals
PHYSICAL EXAMINATION
• Limited
• Inspection
– Anaemia
– Jaundice
– Cyanosis
– Recent alcohol/marijuana ingestion
– Needle tracks/extensive skin disease
WEIGHT - > 50kg
HAEMOGLOBIN – Copper sulphate test
DONOR DEFERRAL
• Temporary
– Pregnancy
– Certain medications
– Vaccination
– Previous transfusion
Acute illnesses
• Permanent
– HIV
– Chronic Renal disease
– Malignant disease
– Creutzfeldt Jakob Disease (CJD)
–
BLOOD COLLECTION
CPDA-1
• Citrate – prevents clotting
• Phosphate – buffer for lactic acid
• Dextrose – ATP generation
• Adenine – ATP synthesis
Storage – 35 days
OPTIMAL ADDITIVE SOLUTION
• Adenine
• Saline
• Glucose
• Mannitol
Storage – 42 days
POSTPHLEBOTOMY CARE
DONOR TESTING
• Blood grouping – ABO, Rh D
• Screen for antibodies
• Screen for infectious agents
– VDRL (syphilis)
– HIV 1,2
– Hepatitis B, C
– HTLV-I,II
NUCLEIC ACID TESTING (NAT)
 For Hepatitis C and HIV
 Shortens the window period