CURRICULUM VITAE Name: Charles B. Huddleston St. Louis, MO, USA Date & Place of Birth: November 18, 1952 Sedalia, MO Current Status: Professor of Surgery, Washington University School of Medicine Chief, Pediatric Cardiothoracic Surgery, St. Louis Children’s Hospital, St. Louis, MO Boards: American Board of Surgery American Board of Thoracic Surgery American Board of Thoracic Surgery, re-cert American Board of Thoracic Surgery, re-cert #32900 1987 #4812 1989 1997 #4812 2007 Education: 1970 - 1974 University of Missouri - Columbia B.A. degree in Chemistry 1974 - 1978 Vanderbilt University School of Medicine Nashville, TN M.D. degree in Medicine Graduate Hospital Experience: 1978 - 1979 Intern, Department of Internal Medicine, Vanderbilt University Hospital, Nashville, Tennessee 1979 - 1981 Resident in Surgery, Division of General Surgery, Department of Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1981 - 1983 Research Fellow, Division of Pharmacology &Cardiac Surg, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 1983 - 1985 Resident in Surgery, Division of General Surgery, Department of Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1985 - 1986 Chief Resident in Surgery, Division of General Surgery, Department of Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1986 - 1988 Fellow in Surgery, Division of Cardiac & Thoracic Surgery, Department of Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1988 - 1989 Senior Registrar, Pediatric Cardiac & Thoracic Surgery, The Hospital for Sick Children, London, England Military Service: 1985 - 1994 Commander, United States Naval Reserve 1991 - 1991 Commander, Active Duty, Fleet Hospital 6 United States Navy, Bahrain, Operation Desert Storm 1994 - present Captain, United States Naval Reserve Academic Appointments: 1989 - 1990 Assistant Professor of Surgery, Division of Cardiothoracic Surgery, Department of Surgery, SUNY Health Science Center at Syracuse, Syracuse, New York 1990 - 1996 Assistant Professor of Surgery, Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine 1996 - 2001 Associate Professor of Surgery, Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine 2001 - present Professor of Surgery, Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine Hospital Appointments: 1989 - 1990 Active Staff, Crouse-Irving Memorial Hospital, Syracuse, NY 1989 - 1990 Active Staff, SUNY Health Science Center, Syracuse, NY 1989 - 1990 Active Staff, St. Joseph's Hospital Health Center, Syracuse, NY 1990 - present Active Staff, Barnes Hospital, St. Louis, MO 1990 - present Active Staff, St. Louis Children's Hospital, St. Louis, MO 1990 - present Active Staff, The Jewish Hospital of St. Louis, St. Louis, MO 1994 - present Chief, Section of Pediatric Cardiothoracic Surgery, Division of Cardiothoracic Surgery, St. Louis Children's Hospital 1994 - present Chief, Lung, Heart & Heart-Lung Transplant Programs, St. Louis Children's Hospital 1994 - 1999 Chief - ECMO Service, St. Louis Children's Hospital 1998 - present Active Staff, Shriners Hospitals for Children, St. Louis, MO Scientific Recognition: Alfred Blalock Surgical Resident Award, Vanderbilt University Medical Center, Nashville, Tennessee, Curator's Scholar, University of Missouri - Columbia, Missouri, Harwell Wilson Award, Vanderbilt University Medical Center, Nashville, Tennessee, Phi Beta Kappa, University of Missouri - Columbia, Missouri, National Societies: American Association of Thoracic Surgery - 1997 - present American College of Surgeons, 1994 - present American Medical Association, 1989 - 1999 Extracorporeal Life Support Organization, 1991 - present H. William Scott, Jr., Society, 1986 - present International Society for Heart and Lung Transplantation, 1995 - present Society of Thoracic Surgeons, 1995 - present Southern Thoracic Surgical Association, 1994 - present Congenital Heart Surgeons Society, 2001 – present American Surgical Association, 2003 - present National Committee Memberships: The Society of Thoracic Surgeons, Program Committee, 2000 - 2003 Editorial Responsibilities 1996 Guest Editor, Seminars in Thoracic and Cardiovascular Surgery, Vol. 8, #3, 276-325 1997 - present Editorial Board, Pediatric Transplantation 2006 – present Editorial Board, Journal of Thoracic and Cardiovascular Surgery 2004 Guest Editor, Seminars in Thoracic and Cardiovascular Surgery, Vol. 16, #3, 195-232 Grant Support: PAST Funding Agency: Period: Grant Title: Grant Number: Principal Investigator: Co-investigators: Total Direct Costs: Annual Direct Costs: Percent of Effort: Mid-America Transplant Services 10/1/92 - 9/30/93 Versatility Of Donor Lung For Transplantation In Growing... N/A Charles B. Huddleston, M.D. $20,000 $20,000 25 Past: Funding Agency: Period: Grant Title: Grant Number: Co-Principal Investigator: Total Direct Costs: N.I.H. 8/1/95-7/31/99 Surgical Treatment of Cardiac Arrhythmias RO1 HL 32257 Charles B. Huddleston, M.D. $1,002,195. Funding Agency: Period: Grant title: Grant Number: Approval Number: Species: Principal Investigator: Total Direct Costs: N.I.H. 5/8/99 - 5/8/2003 Surgical Treatment of Cardiac Arrhythmias. 5R01HL32257-15 98084 Sheep Charles B. Huddleston, M.D. $1,143,194. Funding agency: Period: Title: Life Medical Science 2003-06 A Comparative, Evaluator-Masked, Randomized, Parallel, Multicenter Study to Determined the Safety and Effectiveness of REPEL-CV for Reducing Post-Operative Adhesions Following Pediatric Cardiothoracic Surgery Charles B. Huddleston Principal Investigator: Funding Agency: Period: Title of Project: Number: Principal Investigator: Funding Agency: Period: Title of Project: Principal Investigator: Genzyme Corporation 1999-2001 Evaluation of the Safety and Efficacy of Seprafilm II Adhesions Barrier in Pediatric Cardiac Surgery SF 98-0101 Charles B. Huddleston, MD Sanofi-Sunthelabo Inc. 2000-02 Prophylactic Use of Primacor in Pediatric Patients at Risk of Developing Low Cardiac Output Syndrome Following Cardiac Surgery Charles B. Huddleston, MD BIBLIOGRAPHY: Published Journal Aarticles 1. Lupinetti FM, Huddleston CB, Boucek RJ, Jr., Bender HW, Jr., Hammon JW: Comparison of potassium cardioplegic solution with and without verapamil: effects on immature myocardium. Surgical Forum, 33:331-333, 1982. 2. Huddleston CB, Lupinetti FM, Laws KH, Collins JC, Clanton JA, Hawiger JJ, Oates JA, Hammon JW, Jr.: The effects of RO-22-4679, a thromboxane synthetase inhibitor, on ventricular fibrillation induced by coronary artery occlusion in conscious dogs. Circulation Research, 52(5):608-613, 1983. 3. Huddleston CB, Lupinetti FM, Clanton J, Collins J, Oates JA, Hammon JW, Jr.: Evaluation of a thromboxane synthetase inhibitor in experimental coronary occlusion. Current Surgery, 40:211215, 1983. 4. Atkisson J, Rybicki K, Huddleston CB, Starnes VA, Prager RL, Virmani R: The effect of verapamil cardioplegia on myocardial ultrastructure. Journal of Molecular and Cellular Cardiology, 15:19, 1983. 5. Huddleston CB, Pratt SM: Cymbal player's shoulder [letter]. New England Journal of Medicine, 309(23):1462, 1983. 6. Lupinetti FM, Wareing TH, Huddleston CB, Collins JC, Boucek RJ, Jr., Hammon JW: Canine model of chronic cyanosis: response to global myocardial ischemia. Surgical Forum, 34:294296, 1983. 7. Huddleston CB, Wareing TH, Yu S, Phythyon JM, Hammon JW, Stoney WS: Experimental treatment of cerebral air embolism. Surgical Forum, 34:344-346, 1983. 8. Lupinetti FM, Hammon JW, Jr., Huddleston CB, Boucek RJ, Jr., Bender HW, Jr.: Global ischemia in the immature canine ventricle. Enhanced protective effect of verapamil and potassium. Journal of Thoracic & Cardiovascular Surgery, 87(2):213-219, 1984. 9. Huddleston CB, Wareing TH, Lupinetti FM, Clanton JA, Hammon JW: Pharmacologic protection of platelets during cardiopulmonary bypass: comparison of a thromboxane synthetase inhibitor and a prostacyclin analog. Surgical Forum, 35:350-353, 1984. 10. Huddleston CB, Hammon JW, Jr., Wareing TH, Lupinetti FM, Clanton JA, Collins JC, Bender HW, Jr.: Amelioration of the deleterious effects of platelets activated during cardiopulmonary bypass. Journal of Thoracic & Cardiovascular Surgery, 89(2):190-195, 1985. 11. Lupinetti FM, Wareing TH, Huddleston CB, Collins JC, Boucek RJ, Jr., Bender HW, Jr., Hammon JW, Jr.: Pathophysiology of chronic cyanosis in a canine model: functional and metabolic response to global ischemia. Journal of Thoracic & Cardiovascular Surgery, 90(2):291-296, 1985. 12. Huddleston CB, Stoney WS, Alford WC, Jr., Burrus GR, Glassford DM, Jr., Lea JW, IV, Petracek MR, Thomas CS, Jr.: Internal mammary artery grafts: technical factors influencing patency. Annals of Thoracic Surgery, 42(5):543-549, 1986. 13. Atkinson JB, Rybicki K, Huddleston CB, Starnes VA, Prager RL, Virmani R: The effect of verapamil cardioplegia on myocardial ultrastructure. American Journal of Cardiovascular Pathology, 2(1):69-77, 1988. 14. Williams LF, Jr., Huddleston CB, Sawyers JL, Potts JR, III, Sharp KW, McDougal SW: Is total pelvic exenteration reasonable primary treatment for rectal carcinoma?. Annals of Surgery, 207(6):670-678, 1988. 15. Gault DT, Huddleston CB: Infected sternotomy wounds. European Journal of Cardiothoracic Surgery, 4:48-50, 1990. 16. Creswell LL, Rosenbloom M, Cox JL, Ferguson, Sr. TB, Kouchoukos NT, Spray TL, Pasque MK, Ferguson TB, Jr, Wareing TH, Huddleston CB: Intraaortic balloon counterpulsation: patterns of usage and outcome in cardiac surgery patients. Annals of Thoracic Surgery, 54(1):11-20, 1992. 17. Spray TL, Mallory GB, Canter CE, Huddleston CB, Kaiser LR: Pediatric lung transplantation for pulmonary hypertension and congenital heart disease. Annals of Thoracic Surgery, 54:216-225, 1992. 18. Huddleston CB, Wareing TH, Boucek RJ, Jr., Hammon JW, Jr.: Response of the hypertrophied left ventricle to global ischemia. Comparison of hyperkalemic cardioplegic solution with and without verapamil. Journal of Thoracic & Cardiovascular Surgery, 103(5):919926, 1992. 19. Huddleston CB, Spray TL: Damus-Kaye-Stansel with cavopulmonary connection for single ventricle and subaortic obstruction. Annals of Thoracic Surgery, 55(2):339-346, 1993. 20. Spray TL, Huddleston CB, Canter CE: Technique of transplantation for hypoplastic left heart syndrome with left superior vena cava. Annals of Thoracic Surgery, 55(3):779-781, 1993. 21. Huddleston CB, Rosenbloom M, Goldstein JA, Pasque MK: Biopsy-induced tricuspid regurgitation after cardiac transplantation. Annals of Thoracic Surgery, 57:832-837, 1993. 22. Canter CE, Moorhead S, Huddleston CB, Spray TL: Restrictive atrial septal communication as a determinant of outcome of cardiac transplantation for hypoplastic left heart syndrome. Circulation, 88(2):456-460, 1993. 23. Canter CE, Moorhead S, Saffitz JE, Huddleston CB, Spray TL: Steroid withdrawal in the pediatric heart transplant recipient initially treated with triple immunosuppression. Journal of Heart and Lung Transplantation, 13:74-80, 1993. 24. Tweddell JS, Canter CE, Bridges N, Moorhead S, Huddleston CB, Spray TL: Predictors of postoperative morbidity after infant heart transplant. Annals of Thoracic Surgery, 58(4):972-977, 1994. 25. Triantafillou AN, Pasque MK, Huddleston CB, Pond CG, Cerza RF, Forstot RM, Cooper JD, Patterson GA, Lappas DG: Predictors, frequency, and indications for cardiopulmonary bypass during lung transplantation in adults. Annals of Thoracic Surgery, 57:1248-1251, 1994. 26. Bejarano PA, Dehner LP, Wick MR, Huddleston CB, Spray TL: Isolated lung transplantation in children: pathologic diagnosis and incidence of pulmonary complications. Human Pathology, 25(11):1179-1184, 1994. 27. Spray TL, Mallory GB, Canter CE, Huddleston CB: Pediatric lung transplantation. Indications, techniques, and early results. Journal of Thoracic & Cardiovascular Surgery, 107(4):990-1000, 1994. 28. Johnson MC, Strauss AW, Dowton SB, Spray TL, Huddleston CB, Wood MK: Deletion within chromosome 22 is common in patients with absent pulmonary valve syndrome. American Journal of Cardiology, 76:66-69, 1995. 29. Schlesinger AE, White DK, Mallory GB, Hildeboldt C, Huddleston CB: Estimation of lung volume from chest radiographs and chest CT in children. American Journal of Radiology, 165:151-154, 1995. 30. Bridges ND, Mallory GB, Huddleston CB, Canter CE, Sweet SC, Spray TL: Lung transplantation in children and young adults with cardiovascular disease. Annals of Thoracic Surgery, 59:813-821, 1995. 31. Mendeloff EN, Spray TL, Huddleston CB, Bridges ND, Canter CB, Mallory GB: Lung transplantation for congenital pulmonary vein stenosis. Annals of Thoracic Surgery, 60:903-907, 1995. 32. Pasque MK, Trulock EP, Cooper JD, Triantafillow AN, Huddleston CB, Rosenbloom M, Sundaresan RS, Cox JL, Patterson GA: Single lung transplantation for pulmonary hypertension: single institution experience in 34 patients. Circulation, 92(8):2252-2258, 1995. 33. Jaquiss RD, Huddleston CB, Spray TL: Use of aprotinin in pediatric lung transplantation. Journal of Heart and Lung Transplantation, 14:302-307, 1995. 34. Balzer DT, Moorhead S, Huddleston CB, Saffitz JE, Spray TL, Canter CE: Utility of surveillance biopsies in infant heart transplant recipients. Journal of Heart and Lung Transplantation, 14:1095-1101, 1995. 35. Jaquiss RD, Lusk RP, Spray TL, Huddleston CB: Repair of long segment tracheal stenosis in infancy. Journal of Thoracic & Cardiovascular Surgery, 110:1504-1512, 1995. 36. Santos-Ocampo SD, Sekarski TJ, Saffitz JE, Bridges ND, Huddleston CB, Spray TL, Canter CE: Echocardiographic characteristics of biopsy-proven cellular rejection in infant heart transplant recipients. American Journal of Heart and Lung Transplantation, 15:16-24, 1996. 37. Sweet SC, Spray TL, Huddleston CB, Mendeloff EN, Canter CE, Balzer DT, Bridges ND, Cohen AH, Mallory GB: Pediatric lung transplantation at St. Louis Children's Hospital 19901995. American Journal of Respiratory and Critical Care Medicine, 155:1027-1035, 1997. 38. Gandhi SK, Bromberg BI, Rodefeld MD, Schuessler RB, Boineau JP, Cox JL, Huddleston CB: Lateral tunnel suture line variation reduces atrial flutter after the modified Fontan operation in a canine model. Annals of Thoracic Surgery, 61:1299-1309, 1996. 39. Gandhi SK, Bromberg BI, Schuessler RB, Turken BJ, Boineau JP, Cox JL, Huddleston CB: Characterization and surgical ablation of atrial flutter after the classic Fontan repair. Annals of Thoracic Surgery, 61:1666-1679, 1996. 40. Rodefeld MD, Bromberg BI, Schuessler RB, Boineau JP, Cox JL, Huddleston CB: Atrial futter induced by lateral tunnel construction in the modified Fontan operation. Journal of Thoracic & Cardiovascular Surgery, 111:514-526, 1996. 41. Rodefeld MD, Gandhi SK, Huddleston CB, Turken BJ, Schuessler RB, Boineau JP, Cox JL, Bromberg BI: Anatomically based ablation of atrial flutter in an acute canine model of the modified Fontan operation. Journal of Thoracic & Cardiovascular Surgery, 112:898-907, 1996. 42. Gandhi SK, Bromberg BI, Mallory GB, Huddleston CB: Atrial flutter: a newly recognized complication of pediatric lung transplantation. Journal of Thoracic & Cardiovascular Surgery, 112:984-991, 1996. 43. Gandhi SK, Bromberg BI, Schuessler RB, Boineau JP, Cox JL, Huddleston CB: Left-sided atrial flutter: characterization of a novel complication of pediatric lung transplantation in an acute canine model. Journal of Thoracic & Cardiovascular Surgery, 112:992-1001, 1996. 44. Bridges ND, Mallory GB, Huddleston CB, Canter CE, Spray TL: Lung transplantation in infancy and early childhood. Journal of Heart and Lung Transplantation, 15:895-902, 1996. 45. Hirsch R, Huddleston CB, Mendeloff EN, Sekarski TJ, Canter CE: Infant and donor organ growth after heart transplantation in neonates with hypoplastic left heart syndrome. Journal of Heart and Lung Transplantation, 15:1093-1100, 1996. 46. Mendeloff EN, Huddleston CB, and PayneM: Unusual Cause of Pulmonary Hypertension and Congestive Heart Failure in a Newborn. Annals of Thoracic Surgery, 64:1174-7, 1997. 47. Sundt TM, III, Murphy SF, Barzilai B, Schuessler RB, Mendeloff EN, Huddleston CB, Pasque MK, and Gay WA, JR.: Previous Coronary Artery Bypass Surgery Is Not A Risk Factor For Aortic Valve Replacement. Annals of Thoracic Surgery, 64: 651-658, 1997. 48. Huddleston CB: Extracardiac Lateral Tunnel Modification of the Fontan Procedure. Operative Techniques in Cardiac and Thoracic Surgery. 1997; 2:205-20. 49. Canter CE, Spray TL, Huddleston CB, Mendeloff EN: Intraoperative evaluation of atrioventricular septal defect repair by color flow mapping echocardiography. Updated in 1997. Annals of Thoracic Surgery; 63:592-3, 1997. 50. Hamvas A, Negee LM, Mallory GB Jr., Spray TL, Huddleston CB, August A, Dehner LP, deMello DE, Maxby M, Nelson R, Cole FS, Colten HR: Lung Transplantation for treatment of infants with surfactant protein B deficiency. Journal of Pediatrics; 130:231-9, 1997. 51. Hirsch R, Dent CL, Wood MK, Huddleston CB, Mendeloff EN, Balzer DT, Landt Y, Parrin CA, Landt M, Ladenson JH, Canter CE: Patterns and potential value of cardiac troponin I elevations after pediatric cardiac operations. Annals of Thoracic Surgery; 65:1394-9, 1998. 52. Mendeloff EN, Huddleston CB, Mallory GB, Trulock BP, Sundaresan S, Cooper JD, and Patterson A: Pediatric and Adult Lung Transplantation for Cystic Fibrosis. The Journal of Thoracic and Cardiovascular Surgery, 115:404-14, 1998. 53. Mendeloff EN and Huddleston CB: Lung Transplantation and Repair of Complex Congenital Heart Lesions In Patients With Pulmonary Hypertension. Transplantation Reviews, Vol 12, No 4 (October), 1998: pp 214-221. 54. Huddleston CB, Mendeloff EN, Cohen AH, Sweet S, Balzer DT, and Mallory GB: Lung Retransplantation in Children. Annals of Thoracic Surgery, 66:199-204, 1998. 55. Mendeloff EN and Huddleston CB: Lung Transplantation and Repair of Complex Congenital Heart Lesions in Patients With Pulmonary Hypertension. Seminars in Thoracic and Cardiovascular Surgery, Vol 10, No2 (April), 1998: pp 144-151. 56. Bromberg BI, Schuessler RB, Gandhi SK, Rodefeld MD, Boineau JP, Huddleston CB: A Canine Model of Atrial Flutter following the Intra-atrial Lateral Tunnel Fontan Operation. J Electrocardiology 30 (suppl):85-93, 1998. 56. Huddleston CB, Exil V, Canter CE, and Mendeloff EN: Scimitar Syndrome Presenting in Infancy. Annals of Thoracic Surgery, 67:154-60, 1999. 57. Flippin MJ, Balzer DT, Murphy PR, Ruble SE, Mendeloff EN, Huddleston CB, and Canter CE. Rejection With Heart Failure After Pediatric Cardiac Transplantation. Annals of Thoracic Surgery, 68:176-80, 1999. 58. Minkes RK, Langer JC, Skinner MA, Foglia RP, O’Hagan A, Cohen AH, Mallory GB, Huddleston CB, and Mendeloff EN: Intestinal Obstruction Following Lung Transplantation In Children With Cystic Fibrosis. Journal of Pediatric Surgery, Vol 34:1489-1493, 1999. 59. Huddleston CB, Sweet SC, Mallory GB, Hamvas A, and Mendeloff EN: Lung Transplantation in Very Young Infants. Journal of Thoracic and Cardiovascular Surgery, 118:796-804, 1999. 60. Cohen AH, Mallory GB, Ross K, White DK, Mendeloff EN, Huddleston CB, and Kemp JS: Growth of Lungs after Transplantation in Infants and in Children Younger than 3 Years of Age. Am J Respir Crit Care Med., Vol 159:1747-1751, 1999. 61. Zimmerman AA, Howard TK and Huddleston CB: Combined Lung and Liver Transplantation in a Girl With Cystic Fibrosis. Canadian Journal of Anesthesiology, 46:571-5, 1999. 62. Sundt TM, Bailey MS, Moon MR, Mendeloff EN, Huddleston CB, Pasque MK, Barner HB, and Gay, WA: Quality of Life after Aortic Valve Replacement at the age of >80 years. Circulation, 102 (Supple III) III70-4, 2000. 63. Huddleston CB: What happens if the heart won’t start? Pediatric Transplantation 4:89-91, 2000. 64. Cohen AH, Sweet SC, Mendeloff EN, Mallory GB Jr., Huddleston CB, Krause M, Kelly H, Hayashi R, DeBaum MR: High incidence of post-transplant lymphoproliferative disease in pediatric patients with cystic fibrosis. American Journal of Respiratory Critical Care Medicine; 161:1252-5, 2000. 65. Hayashi RJ, Kraus MD, Lahoti A, Canter CE, Cohen AH, Hmiel P, Howard T, Huddleston CB, Lowell JA, Mallory GB, Mendeloff EN, Molleston J, Sweet S, and DeBaun MR: Post Transplant Lymphoproliferative Disease in Children: Correlation of Histology to Clinical Behavior. Journal of Pediatric Hematology/Oncology; 23 (1):14-18, 2001. 66. Huddleston CB, Balzer DL, and Mendeloff EN: Repair of Anomalous Left Main Coronary Artery Arising From The Pulmonary Artery In Infants - Long Term Impact On The Mitral Valve. Annals Of Thoracic Surgery 71:1985-9. 2001. 67. Kao B, Balzer DT, Huddleston CB, and Canter CE: Long-term Prostacyclin Infusion to Reduce Pulmonary Hypertension in a Pediatric Cardiac Transplant Candidate Prior to Transplantation. J Heart Lung Transplant 20:785-8, 2001. 68. Kimberling MT, Balzer DT, Hirsch R, Mendeloff EN, Huddleston CB, and Canter CE.: Cardiac transplantation for pediatric restrictive cardiomyopathy: presentation, evaluation, and short-term outcome. J Heart Lung Transplant 21:455-9. 2002. 69. Ibrahim JE, Sweet SC, Flippin M, Dent C, Mendeloff EN, Huddleston CB, and Canter CE: Rejection is reduced in thoracic organ recipients when transplanted in the first year of life. J Heart Lung Transplant 21:311-8. 2002. 70. Chen LE, Langer JC, Dillon PA, Foglia RP, Huddleston CB, Mendeloff EN, and Minkes RK: Management of Late-Stage Parapneumonic Empyema. J of Pediatric Surgery 37:371-4, 2002. 71. Mendeloff EN, Meyers BF, Sundt TM, Guthrie TJ, Sweet SC, Balzer DT, Trulock EP, Pasque MK, Cooper JD, Huddleston CB, and Patterson GA: Lung Transplantation For Pulmonary Vascular Disease. Annals of Thoracic Surgery, 73:209-219, 2002. 72. Yoon HE, Huddleston CB, Miyoshi S, Matsuda H, Kamike W, and Patterson GA: Pulmonary Function After Living Donor Lung Transplantation. Transplantation Proceedings, 33:1626-1627, 2001. 73. Moon MR. Sundt TM. Pasque MK. Barner HB. Huddleston CB. Damiano RJ Jr. Gay WA Jr.: Does the extent of proximal or distal resection influence outcome for type A dissections?. Annals of Thoracic Surgery. 71:1244-50, 2001. 74. Huddleston CB: How do you study blue? Journal of Thoracic & Cardiovascular 124:14-5, 2002. 75. Surgery. Huddleston CB. Bloch JB. Sweet SC. de la Morena M. Patterson GA. Mendeloff EN. Lung transplantation in children. Annals of Surgery. 236:270-6, 2002. 76. Lu KC. Jaramillo A. Lecha RL. Schuessler RB. Aloush A. Trulock EP. Mendeloff EN. Huddleston CB. Patterson GA. Mohanakumar T. Interleukin-6 and interferon-gamma gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantation. Transplantation. 74:1297-302, 2002 77. Forsen JW Jr. Lusk RP. Huddleston CB. Costal cartilage tracheoplasty for congenital longsegment tracheal stenosis. Archives of Otolaryngology -- Head & Neck Surgery. 128:1165-71, 2002. 78. Lu KC. Jaramillo A. Mendeloff EN. Huddleston CB. Sweet SC. Patterson GA. Mohanakumar T. Concomitant allorecognition of mismatched donor HLA class I- and class II-derived peptides in pediatric lung transplant recipients with bronchiolitis obliterans syndrome. Journal of Heart & Lung Transplantation. 22:35-43, 2003. 79. Pechet TV. de le Morena M. Mendeloff EN. Sweet SC. Shapiro SD. Huddleston CB. Lung transplantation in children following treatment for malignancy. Journal of Heart & Lung Transplantation. 22:154-60, 2003. 80. Huddleston CB. Have we met the expectations of heart and lung transplantation in children? Seminars in Thoracic & Cardiovascular Surgery. Pediatric Cardiac Surgery Annual. 6:164-70, 2003. 81. Danziger-Isakov LA. DelaMorena M. Hayashi RJ. Sweet S. Mendeloff E. Schootman M. Huddleston CB. DeBaun MR. Cytomegalovirus viremia associated with death or retransplantation in pediatric lung-transplant recipients. Transplantation. 75(9):1538-43, 2003. 82. Lee R. Mendeloff EN. Huddleston C. Sweet SC. de la Morena M. Bilateral lung transplantation for pulmonary hypoplasia caused by congenital diaphragmatic hernia. Journal of Thoracic & Cardiovascular Surgery. 126:295-7, 2003. 83. McOmber D. Ibrahim J. Lublin DM. Saffitz JE. Ong-Simon C. Mendeloff EN. Huddleston CB. Canter CE. Non-ischemic left ventricular dysfunction after pediatric cardiac transplantation: treatment with plasmapheresis and OKT3. Journal of Heart & Lung Transplantation. 23:552-7, 2004. 84. Hamvas A. Nogee LM. White FV. Schuler P. Hackett BP. Huddleston CB. Mendeloff EN. Hsu FF. Wert SE. Gonzales LW. Beers MF. Ballard PL. Progressive lung disease and surfactant dysfunction with a deletion in surfactant protein C gene. American Journal of Respiratory Cell & Molecular Biology. 30:771-6, 2004. 85. Kreisel D. Krupnick AS. Huddleston CB. Outcomes and late complications after pulmonary resections in the pediatric population. Seminars in Thoracic & Cardiovascular Surgery. 2004;16:215-9. 86. Huddleston CB. Pectus excavatum. Seminars in Thoracic & Cardiovascular Surgery. 2004;16:22532 87. Huang J. Trinkaus K. Huddleston CB. Mendeloff EN. Spray TL. Canter CE. Risk factors for primary graft failure after pediatric cardiac transplantation: importance of recipient and donor characteristics. Journal of Heart & Lung Transplantation. 23:716-22, 2004. 88. Huddleston CB. Mediastinal wound infections following pediatric cardiac surgery. Seminars in Thoracic & Cardiovascular Surgery. 16:108-12, 2004. 89. Nicolas RT. Hills C. Moller JH. Huddleston CB. Johnson MC. Early outcome after Glenn shunt and Fontan palliation and the impact of operation during viral respiratory season: analysis of a 19year multi-institutional experience. Annals of Thoracic Surgery. 79:613-7; discussion 617, 2005. 90. Choong CK. Sweet SC. Guthrie TJ. Mendeloff EN. Haddad FJ. Schuler P. De La Morena M. Huddleston CB. Repair of congenital heart lesions combined with lung transplantation for the treatment of severe pulmonary hypertension: a 13-year experience. Journal of Thoracic & Cardiovascular Surgery. 129:661-9, 2005. 91. Danziger-Isakov LA. Sweet S. Delamorena M. Huddleston CB. Mendeloff E. Debaun MR. Epidemiology of bloodstream infections in the first year after pediatric lung transplantation. Pediatric Infectious Disease Journal. 24:324-30, 2005 92. Choong CK. Hu DZ. Huddleston CB. Pulmonary segmental venous infarction after living-donor lobar lung transplantation. Journal of Thoracic & Cardiovascular Surgery. 130:919-21, 2005 93. Meyers BF. de la Morena M. Sweet SC. Trulock EP. Guthrie TJ. Mendeloff EN. Huddleston C. Cooper JD. Patterson GA. Primary graft dysfunction and other selected complications of lung transplantation: A single-center experience of 983 patients. Journal of Thoracic & Cardiovascular Surgery. 2005;12):1421-9. 94. Choong CK. Sweet SC. Zoole JB. Guthrie TJ. Mendeloff EN. Haddad FJ. Schuler P. De la Morena M. Huddleston CB. Bronchial airway anastomotic complications after pediatric lung transplantation: incidence, cause, management, and outcome. Journal of Thoracic & Cardiovascular Surgery. 2006;131:198-203. 95. Choong CK. Haddad FJ. Huddleston CB. Bell J. Guthrie TJ. Mendeloff EN. Schuler P. De la Morena M. Sweet SC. Role of open lung biopsy in lung transplant recipients in a single children's hospital: a 13-year experience. Journal of Thoracic & Cardiovascular Surgery. 2006;131:204-8. 96. Kozower BD. Sweet SC. de la Morena M. Schuler P. Guthrie TJ. Patterson GA. Gandhi SK. Huddleston CB. Living donor lobar grafts improve pediatric lung retransplantation survival. Journal of Thoracic & Cardiovascular Surgery. 2006;131:1142-7. 97. Kotru A. Sheperd R. Nadler M. Chapman W. Huddleston C. Lowell J. Combined lung and liver transplantation: the United States experience. Transplantation. 2006;82:144-5. 98. Checchia PA. McGuire JK. Morrow S. Daher N. Huddleston C. Levy F. A risk assessment scoring system predicts survival following the Norwood procedure. Pediatric Cardiology. 27:62-6, 2006. 99. Gandhi SK. Canter CE. Kulikowska A. Huddleston CB. Infant heart transplantation ten years later--where are they now?. Annals of Thoracic Surgery. 83:169-71; discussion 172, 2007. 100. Elizur A. Sweet SC. Huddleston CB. Gandhi SK. Boslaugh SE. Kuklinski CA. Faro A. Pre-transplant mechanical ventilation increases short-term morbidity and mortality in pediatric patients with cystic fibrosis. Journal of Heart & Lung Transplantation. 26:127-31, 2007. 101. Faro A. Shepherd R. Huddleston CB. Lowell J. Gandhi S. Nadler M. Sweet SC. Lower incidence of bronchiolitis obliterans in pediatric liver-lung transplant recipients with cystic fibrosis. Transplantation. 83:1435-9, 2007. 102. Spivey JF. Singleton D. Sweet S. Storch GA. Hayashi RJ. Huddleston CB. DanzigerIsakov LA. Safety and efficacy of prolonged cytomegalovirus prophylaxis with intravenous ganciclovir in pediatric and young adult lung transplant recipients. Pediatric Transplantation. 11:312-8, 2007. 103. Holt DB. Lublin DM. Phelan DL. Boslaugh SE. Gandhi SK. Huddleston CB. Saffitz JE. Canter CE. Mortality and morbidity in pre-sensitized pediatric heart transplant recipients with a positive donor crossmatch utilizing peri-operative plasmapheresis and cytolytic therapy. Journal of Heart & Lung Transplantation. 26:876-82, 2007. 104. Kaiser SP. Melby SJ. Zierer A. Schuessler RB. Moon MR. Moazami N. Pasque MK. Huddleston C. Damiano RJ Jr. Lawton JS. Long-term outcomes in valve replacement surgery for infective endocarditis. Annals of Thoracic Surgery. 83:30-5, 2007. IV. 1. BOOKS/BOOK CHAPTERS Spray TL, Huddleston CB: Pediatric lung transplantation. In: Chest Surgery Clinics of North America, Cooper JD, Patterson GA, (eds.), Churchill, Livingstone, London, 1992, 123-144. 2. Huddleston CB, Spray TL: Pediatric lung transplantation and the use of reduced-size lungs for transplantation in children. In: Medical Intelligence Unit, Kron IL, Kern JA, (eds.), R. G. Landes, Austin, Texas, 1993, 1-22. 3. Spray TL, Huddleston CB: Pediatric lung transplantation: Early and intermediate results. In: Current Topics in General Thoracic Surgery, Patterson GA, Couraud L, (eds.), Elsevier Publishing Co.: New York, 1995, 425-447. 4. Huddleston CB: Pediatric heart transplantation. In: Mastery of Cardiothoracic Surgery, Spray TL, Kaiser LR, Kron IL, (eds.), Little, Brown and Company: Boston, MA, 1995. 5. Huddleston CB: Pediatric heart transplantation. In: The Transplantation and Replacement of Thoracic Organs, Cooper DK, (ed.), Kluwer Academic Publishers, Boston, Dordrecht, London, 1996, 367-377. 6. Huddleston CB: Airway complications in children following lung transplantation. In: The Transplantation and Replacement of Thoracic Organs, Cooper DK, (ed.), Kluwer Academic Publishers, Boston, Dordrecht, London, 1996, 581-588. 7. Clabby ML, Canter CE, Strauss AW, Huddleston CB: Total Anomalous Pulmonary Venous Connection. In: Surgery of Congenital Heart Disease: Pediatric Cardiac Care Consortium 1984-1995. Moller JH (ed.). Armonk, NY: Futura Publishing Company, Inc., 1998. 8. 8. Huddleston CB and Mendeloff EN: Scimitar Syndrome. In: Advances in Cardiac Surgery, Mosby, Inc., Vol 11, 1999. 9. 9. Ibriham J, Mendeloff EN, Huddleston CB: The use of extracorporeal membrane oxygenation for peri-operative support in pediatric lung transplantation patients. In: Mechanical support for cardiac and respiratory failure in pediatric patients. Marcel Dekker, Inc., New York, 2001. 10. Huddleston CB, and Bromberg BI: Prevention of Postoperative Arrhythmias. In: Cardiac Arrhythmias After Surgery For Congenital Heart Disease, Arnold, London, Sydney, Auckland and co-published by Oxford University Press Inc., New York, 2001. 10. Hudd Huddleston CB: Correction of Complete Atrioventricular Canal. In: Operative Techniques in Thoracic and Cardiovascular Surgery. Cox JL. WB Saunders, Philadelphia. 2002 11. Huddleston CB: Complete AV Canal. In: Current Therapy in Thoracic and Cardiovascular Surgery. Yang SC, Cameron DE (editors). Elsevier. London. 2004 12. H 13. 14. Asdf; Huddleston CB and Cooper J: Lung Transplantation. In: Pediatric Surgery, Grosfeld JL, O’Neill JA, Fonkalsrud EW, Coran AG. (Sixth edition). Mosby Elsevier. Philadelphia. 2006. Huddleston CB: Pectus Excavatum in Adults. In: Difficult Decisions in Thoracic Surgery. Ferguson MK (Ed.). Springer, New York. 2006 Huddleston CB: Lung Transplantation in Children. In: Seminars in Pediatric Surgery. Pescowitz M (Ed.) Elsevier, Philadelphia. 2006 15. Huddleston CB: Chest Wall Deformities. In: Thoracic Surgery. Pearson FG, Patterson GA, Deslauriers J (Eds.) Churchill Livingstone, London, 2006 16. Huddleston CB: Congenital Lung Abnormalities. In: Thoracic Surgery. Pearson FG, Patterson GA, Deslauriers J (Eds.) Churchill Livingstone, London, 2006 17. Huddleston CB: Donor Evaluation, Surgical Technique, and Perioperative Management: Lung and Heart-Lung Transplantation. 18. J