Answers28. january

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January 28, 2005

Multiple choice questions
(numbers in brackets indicate the number of correct answers)
DNA was first isolated in the
17th century 
18th century 
19th century 
20th century 
Components of DNA are
Phosphate, ribose, pyridines, and purines
Phosphate, ribulose, and nucleotides
Sulfate, ribose, pyrimidines, and purines
Phosphate and nucleotides
Phosphate, deoxyribose, pyrimidines, and purines
(1)





(1)
The DNA double helix is stabilized by
Ionic bonds

Covalent bonds

Hydrogen bonds

Hydrophobic interactions

(2)
DNA is synthesized in
5’->3’ direction

3’->5’ direction

in both directions

(1)
The major form of DNA in cells is
A-DNA

B-DNA

C-DNA

Z-DNA

(1)
Z-DNA
winds to the left
is thicker than B-DNA
has a flat major groove
has a broad minor groove
(2)




Sizes of genomes of free-living organisms have been found to range from
approximately
2-200 Mbp

0.5-1,000 Mbp

100-2,000,000 Mbp

1,000-1,000,000,000 Mbp

0.5-200,000 Mbp

[1 Mbp = 1 million bp]
(1)
The size of the human genome is about
0.5 Mbp

10 Mbp

200 Mbp

3,000 Mbp

40,000 Mbp 
500,000 Mbp 
(1)
Most sequences in the human genome belong to
Genes

Pseudogenes

Gene fragments

Interspersed repeats 
Tandem repeats

(1)
Which of the following genomes is richest in interspersed repeat sequences?
Drosophila genome

Human genome

Maize genome

Saccharomyces genome

E. coli genome

(1)
Which genome has the fewest introns?
Drosophila genome

Human genome

Maize genome

Saccharomyces genome

E. coli genome

(1)
A nucleosome consists of
Chromatin and nucleotides
Chromatin and histones
DNA and chromatin
DNA and histones
Nucleoids and histones





(1)
Centromers contain
Repeated DNA
Chromatids
Telomeres
Proteins
Microtubules
Genes

(3)






Gene density can be high
in telomeres
anywhere on the chromosomes
in centromeres
in metaphase chromosomes
in anaphase chromosomes





(1)
Self study questions at the end of chapters 1 and 2 of the GENOMES textbook:
Chapter 1: 7., 10., 11., 14.
Chapter 2: 1., 3., 10., 15.
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