University of British Columbia Curriculum Vitae for Faculty Members Date: Initial: FIRST NAME: 1. SURNAME : Kollmannsberger 2. DEPARTMENT/SCHOOL: Medicine / Div. of Medical Oncology 3. FACULTY: Medicine 4. PRESENT RANK: Clinical Associate Professor MIDDLE NAME(S): SINCE: February 02th 2009 CK Christian Kurt 1/2006 5. POST-SECONDARY EDUCATION University or Institution Degree Subject Area Dates University of British Columbia Clinical Associate Professor of Medicine Dept. of Medicine January 2006 – present British Columbia Cancer Agency Medical Oncologist Div. of Medical Oncology January 2004 - present University of Tuebingen Associate Professor Hematology / Medical Oncology 2003-2004 University of Tuebingen Hematologist / Medical Oncologist Hematology / Oncology 2001-2003 University of Tuebingen, Germany Internist Internal Medicine 1996-2001 University of Munich, Germany - Internal Medicine 1995-1996 University of Freiburg, Germany - Internal Medicine 1993-1995 University of Washington, Seattle - Clinical elective in Gastroenterology 1992 McGill University, Montréal - Clinical elective in Cardiology 1992 University of Munich MD Medicine 1989-1993 University of Regensburg, Germany - Medicine 1986-1988 1 Special Professional Qualifications Royal College of Physicians and Surgeons of Canada Academic Certification 2008 Certification - German Board of Hematology / Oncology 2003 Certification - German Board of Internal Medicine 2001 Certification - European Society of Medical Oncology 2000 Medical Council of Canada Evaluating Examination 1996 United States Medical Licensure Examination Step I, II, III 1995 / 1996 Final Medical Examination 1993 6. EMPLOYMENT RECORD Prior University, Company or Organization Rank or title Dates University of Tuebingen, Germany Dept. of Internal Medicine Associate Professor (“Privatdozent”) June 23rd 2003 - present University of Tuebingen, Germany Dept. of Internal Medicine Fellow Hematology / Medical Oncology 2001-2003 University of Tuebingen, Germany Dept. of Internal Medicine Resident 1997-2000 University of Munich, Germany Dept. of Internal Medicine Resident 1995-1996 University of Freiburg, Germany Dept. of Internal Medicine Resident 1993-1995 Present University, Company or Organization Rank or title Dates University of British Columbia / Clinical Associate Professor January 1st 2006 – present British Columbia Cancer Agency Medical Oncologist January 26th 2004 - present 7. LEAVES OF ABSENCE 2 University, Company Or Organization at which Leave was taken Type of Leave Dates 8. TEACHING (a) Areas of special interest and accomplishments (b) Courses Taught at the University of Tuebingen, Germany / University of British Columbia: Year Session Course Number Scheduled Class Hours Taught Hours Size Lecture Tutorials 2001 2003 Physical examination 2 per week 8 X 2001 2003 Clinical-oncological case conference 2 per week 8-15 X 2001 2003 Surgical-oncological case conference 2 per week 8-15 X 2001 2003 Clinical Oncology 1 per week 10 X 2004 Academic Half-day 1.5 hours 10 x 2005 Academic Half-day 1.5 hours 10 x 2006 Academic Half-day 1.5 hours 10 x 2006 Clinical skills course 8 hours 2 2007 Academic half day 1.5 hours 10 2007 Clinical skills course 8 hours 2 Labs Other x x x 3 2008 Clinical skills course 8 hours 2 2008 Academic half day 1.5 hours 10 x x (c) Graduate Students supervised at the University of Tuebingen, Germany: Student Name Program Type Year Start Principal Supervisor Co-Supervisors Finish Karin Oechsle Medicine (MD) 1999 2001 Prof. C. Bokemeyer MD Dr. C. Kollmannsberger Barbara Schuto Medicine (MD) 2002 2004 Prof. C. Bokemeyer MD Dr. C. Kollmannsberger (d) Continuing Education Activities (e) Visiting Lecturer (indicate university/organization and dates) (f) Other - 9. SCHOLARLY AND PROFESSIONAL ACTIVITIES (a) Areas of special interest and accomplishments Evaluation of prognostic factors and development of new therapeutic strategies in patients with urological and gastrointestinal malignancies, particularly germ cell, renal cell and gastric cancer. Development of adjuvant and palliative therapeutic strategies in patients with upper GI malignancies. Investigation of late toxicity and secondary neoplasms in patients treated for Hodgkin´s disease or germ-cell tumors. Development of new anti-tumor agents in patients with solid tumors, particularly germ-cell cancer, renal cell cancer and GI malignancies. 4 (b)+(c) Research or equivalent grants/contracts (indicate under COMP whether grants were obtained competitively (C) or non-competitively (NC)) Granting Principal Subject COMP $ Per Year Bristol-Myers Squibb, Germany Paclitaxel in patients with metastatic gastric cancer NC 32 000 1997 2001 C. Bokemeyer Fortune program - University of Tuebingen Molecular prognostic factors in patients with refractory germ cell cancer C 22 000 2000 2001 C. Kollmannsberger Ribosepharm, Germany Bendamustin in patients with refractory germ cell cancer NC 4 000 2001 2002 C. Kollmannsberger C. Bokemeyer Aventis Pharma, Irinotecan in patients with refractory germ cell cancer NC 8 000 2001 2002 C. Kollmannsberger C. Bokemeyer Fortune program - University of Tuebingen Meta-analysis on carboplatin in seminoma C 22 000 2001 2002 C. Kollmannsberger C. Bokemeyer Bristol-Myers Squibb, Germany Paclitaxel for adjuvant treatment of gastric cancer NC 27 000 2001 2003 C. Kollmannsberger C. Bokemeyer Lilly, Germany Gemcitabine/Oxaliplatin testis cancer NC 16 000 2002 2003 C. Kollmannsberger C. Bokemeyer AKF program University of Tuebingen Paclitaxel for adjuvant treatment of gastric cancer C 20 000 2001 2003 C. Kollmannsberger C. Bokemeyer AKF program University of Tuebingen Molecular prognostic factors in gastric cancer C 2002 2003 C. Kollmannsberger Amgen, Germany Darbepoetin cancer testis NC 20 000 2003 2006 C. Bokemeyer Pfitzer Canada SU011248 in refractory Germ cell cancer NC 340 000 2006 2008 C. Kollmannsberger Agency Germany in in 23 000 Year Investigator Co-Investigator(s) C. Kollmannsberger C. Bokemeyer Mayer F. W. Budach C. Bokemeyer Mayer F. C. Kollmannsberger C. Bokemeyer M. Moore E. Winquist T. Chen L. Wood P. Czaykowski 5 (d) Invited Presentations 1. VIII Erlanger Clinical Conference on Lung Diseases, Erlangen, Germany 1997: „Advances in Pneumology: High-dose chemotherapy with autologous stem cell support in small cell lung cancer. 2. Grand Rounds, Dept. Of Medical Oncology, University of Essen, Germany 1998. "Treatment associated leukemia” 3. UICC Symposium on Testicular Cancer, Tuebingen, Germany 1999. „Secondary malignancies". 4. Annual Meeting of the German Society of Hematology/Medical Oncology, 1999. "Treatment-related malignancies following treatment of germ cell cancer 5. Post-ASCO Meeting for Community Oncologists, Muenchen, 1999: “Advances in the treatment of gastric cancer” 6. Teaching Course “Clinical Oncology” for Residents and Fellows, Frankfurt 2000 (supported by the German Cancer Society). "Soft-tissue and bone sarcomas". 7. Teaching Course “Clinical Oncology” for Residents and Fellows, Frankfurt, Germany 2001 (supported by the German Cancer Society). "Standards and current developments in the treatment of upper gastrointestinal malignancies“ 8. Annual Meeting of the German Society of Hematology/Medical Oncology 2001. "Therapy-related myelodysplastic syndrome and leukemia following chemotherapy treatment of patients with potentially curable malignancies." 9. Post-ASCO Meeting for Community Oncologists, Munich, Germany 2001: "Advances in the treatment of esophageal and gastric cancer“. 10. Teaching Course “Clinical Oncology” for Residents and Fellows, Stuttgart, Germany 2002 (supported by the German Cancer Society)."Advances in the treatment of upper gastrointestinal malignancies” 11. Grand Rounds, Department of Surgery, University of Munich, Germany, 2002: Advances in the Adjuvant Treatment of Gastric Cancer. 12. Annual Meeting of German Community Oncologists Group, Garmisch-Partenkirchen, Germany 2003: “Chemotherapy of Gastric Cancer”. 13. Annual Meeting of the German Society of Hematology / Medical Oncology, 2003: “Late toxicity following chemotherapy of testicular cancer”. 14. MASCC/ISOO 15th. International Symposium on Supportive Care in Cancer, Berlin, Germany 2003. “Therapyrelated neoplasms after chemotherapy and/or radiation therapy in patients with potentially curable malignancies”. 15. Conference on Molecular Targeted Therapy of Cancer, Stuttgart, Germany 2003: “Targeting EGFR: Small Molecule Tyrosine Kinase Inhibitors - Preclinical studies”. 16. Second International Conference on Germ Cell Tumors, Ravenna., Italy: “Prognostic and Predictive Factors in Germ Cell Cancer”. 17. 26th Congress of the German Cancer Society, Berlin, Germany 2004 “Anti-EGFR-Concepts: Preclinical and Clinical Studies”. 18. 26th Congress of the German Cancer Society, Berlin, Germany 2004: “Adjuvant Therapy of Gastric Cancer”. 19. Annual Meeting of the British Columbia Cancer Agency, Vancouver 2004. “Advances in the chemotherapy of upper gastrointestinal malignancies”. 20. Annual Community Oncologists' Meeting, Vancouver 2004: “Advances in the Chemotherapy of Bladder Cancer”. 21. Teaching Course “Clinical Oncology” for Residents and Fellows, Berlin, Germany 2004 (supported by the German Cancer Society)."Treatment of upper gastrointestinal malignancies” 6 22. Annual Meeting of the German / Swiss / Austrian Societies of Hematology/Medical Oncology, Hannover, Germany 2005: “ Advances in the treatment of hormone-refractory prostate cancer”. 23. Atlantic Canada Oncology Meeting, Prince Edward Island June 2006: “Advances in the treatment of testis cancer”. 24. The Canadian Association of Pharmacy in Oncology - National Oncology Pharmacy Symposium October 2006: “Advances in the treatment of renal cell carcinoma”. 25. Saskatoon Cancer Centre Grand Rounds, December 2006: “Novel treatments in renal cell carcinoma” 26. Regina Cancer Centre Grand Rounds, February 2007: “Renal cell carcinoma – new strategies”. 27. Radiation Oncology Grand Rounds, Vancouver December 2006: “VEGF-Receptor blockade – A Breakthrough in the treatment of Advanced renal cell carcinoma ?” 28. Cancer Care Manitoba Grand Rounds, June 2007: “Renal cell carcinoma – novel therapies”. 29. Canadian Association of Nurses in Oncology Annual Meeting, Vancouver October 2007: “New agents in renal cancer: novel drugs – novel side effects”. 30. Canadian Association of Nurses in Oncology Annual Meeting, Vancouver October 2007: “Treatment of hormone-refractory prostate cancer: chemotherapy or no chemotherapy”. 31. Canadian Urologic Oncology Group Retreat, Vancouver October 2007: “Targeted Therapies for RCC”. 32. Canadian Urologic Oncology Group Retreat, Vancouver October 2007: “Cost & Benefit of New Drugs: Worthwhile? Negligible? Unaffordable?” 33. Issues and Controversies in Prostate Care, Cancun January 2008: “What is the biology of renal cell carcinoma” 34. Issues and Controversies in Prostate Care, Cancun January 2008: “The VEGF pathway in RCC” 35. Issues and Controversies in Prostate Care, Cancun January 2008: “Management of toxicity of renal cell carcinoma treatment”. 36. European Society of Medical Oncology International Symposium on Testicular Cancer, Munich May 2008: “Treatment of malignant non-germ cell transformation” 37. European Society of Medical Oncology International Symposium on Testicular Cancer, Munich May 2008: “New treatment options” 38. Canadian Urology Association Annual Meeting, Edmonton June 2008: “Chemotherapy for stage I nonseminomatous germ cell cancer” 39. 28th Annual Canadian Cancer Registry Professionals Workshop (CCRPW) October 2008: “Genitourinary tumors” 40. Issues and Controversies in Prostate Care, Cancun January 2009: “Adjuvant and neoadjuvant chemotherapy for high risk localized prostate cancer” 41. Issues and Controversies in Prostate Care, Cancun January 2009: “What is the Rationale for Multimodal Therapy? A Biological Perspective” 7 42. American Society of Clinical Oncology Genitourinary Symposium Orlando February 2009: “Testicular Cancer: Second line therapy and beyond” (e) Other Presentations (Oral presentations only) 1. Annual Meeting of the German Society of Hematology/Medical Oncology 1997. Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer. Published in: Br J Cancer, 77: 1355-1362, 1997. 2. 23rd Congress of the European Society of Medical Oncology, Athens., Greece 1998: "FDG-PET for the evaluation of high-dose chemotherapy (HD-CTX) in patients with metastatic germ cell tumors (GCT)." Published in: Cancer, 94: 2353-2362, 1998. 3. 23rd Congress of the European Society of Medical Oncology, Athens., Greece 1998: "A phase II trial of paclitaxel, cisplatin, and weekly 24h infusion of 5-fluorouracil (5-FU) / folinic acid in patients (pts) with advanced gastric cancer." Published in: Br J Cancer, 83: 458-462, 1998. 4. 34th Annual Meeting of the American Society of Clinical Oncology, Los Angeles., USA 1998: "Secondary acute myeloid leukemia (S-AML) or myelodysplastic syndrome (S-MDS) following high-dose etoposide (>/= 2 g/m) containing chemotherapy in 302 patients with germ cell tumors (GCT)." Published in: J Clin Oncol, 16: 3386-3391, 1998. 5. 35th Annual Meeting of the American Society of Clinical Oncology, Atlanta, USA 1999: First-line high-dose chemotherapy (HD-CT) +/- radiation therapy (RTX) in patients (pts) with CNS metastases of nonseminomatous germ cell tumors (GCT). Published in: Ann Oncol, 11: 553-559, 1999. 6. Annual Meeting of the German Society of Hematology/Medical Oncology 1999: "First-line high-dose chemotherapy with autologous stem cell support versus standard BEP/VIP in patients with advanced germ cell cancer" Published in: J Clin Oncol, 17: 3450-3456, 1999. 7. 25th Congress of the European Society of Medical Oncology, Hamburg, Germany. "Reduction of skin toxicity of pegylated liposomal doxorubicin (PLD) by concomitant administration of dexamethasone (DEX) and pyridoxine (PYR) in patients (pts) with antracycline-sensitive malignancies - a phase I/II trial." Published in: Ann Oncol, 11 (Suppl. 4): 136-(abstract 623P), 2000. 8. 36th Annual Meeting of the American Society of Clinical Oncology, New Orleans, USA 2000: A phase II study of paclitaxel, weekly 24-hour continuous infusion (CI) of 5-fluorouracil / folinic acid (FA) and cisplatin in patients (pts) with advanced gastric cancer. Published in: Br J Cancer, 83: 458-462, 2000. 9. Annual Meeting of the German Society of Hematology/Medical Oncology 2000: "[18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) for the early prediction of response to high-dose chemotherapy (HD-CT) in patients (pts) with metastatic germ cell cancer." Published in: Br J Cancer, 86: 506-511, 2000. 10. 37th Annual Meeting of the American Society of Clinical Oncology, San Francisco., USA 2001: "Oxaliplatin in patients (pts) with cisplatin-refractory germ cell cancer (GCT)." Published in: J Clin Oncol, 20: 2031-2037, 2001. 11. Annual Meeting of the German Society of Hematology/Medical Oncology 2001: "Lack of overexpression of the EGF receptor family in refractory germ cell cancer (GCT)." Published in: Cancer, 95: 301-308, 2001. 12. Annual Meeting of the German Society of Hematology/Medical Oncology 2001: "Oxaliplatin (OX) in patients (pts) with relapsed or cisplatin refractory germ cell cancer (GCT). Final results of a German Testicular 8 Cancer Study Group investigation." Published in: J Clin Oncol, 20: 2031-2037, 2001. 13. 38th Annual Meeting of the American Society of Clinical Oncology, Orlando, USA 2002: Outcome of patients (pts) with "poor prognosis" germ cell cancer (GCT) relapsing after primary high-dose chemotherapy plus stem cell support (pHD/PBSCT). Published in: Eur J Cancer, 39: 775-782, 2002. 14. Annual Meeting of the German Society of Hematology/Medical Oncology 2002: Adjuvant radiochemotherapy (RTx/CTx) using 5-FU/Folinnic acid (FA)/Cisplatin (CDDP)/Paclitaxel (P) and radiation in patients (pts) with completely (R0) resected high-risk gastric cancer (UICC stages II-IV (M0)). Published in: Onkologie, 25 (Sonderheft 4): 49-(abstract 169), 2002. 15. Annual Meeting of the German Society of Hematology/Medical Oncology 2003: Combination chemotherapy with gemcitabine plus oxaliplatin in patients with refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group (GTCSG). Published in: J Clin Oncol, 22: 108-114, 2003. 16. Annual Meeting of the German Society of Hematology/Medical Oncology 2003: Single agent carboplatin versus cisplatin-based combination chemotherapy in patients with advanced seminoma: a meta-analysis of prospective European trials. Published in: Br J Cancer 683-687, 2003. 17. Annual Meeting of the German Society of Hematology/Medical Oncology 2003: Adjuvant radiochemotherapy using 5-FU/Folinic acid/cisplatin +/- Paclitaxel and radiation in patients with completely (R0) resected highrisk gastric cancer (UICC stages II-IV (M0): A phase II study of the AIO/ARO/ACO. Published in: Ann Oncol 16: 1326-1333, 2005. (f) Other (g) Conference Participation (Organizer, Keynote Speaker, etc.) Member of the organizing committee and local organizer of the UICC-Meeting on Testicular Cancer 1999. Member and secretary of the European Consensus Conference on the treatment of testicular cancer 2002. Speaker, International Conference on Supportive Care in Cancer 2003 Speaker, International Conference on Germ Cell Cancer 2003 Secretary of the German Cancer Congress of the German Society of Cancer 2004 Speaker, Congress of the German Cancer Society 2004 Speaker, Atlantic Canada Oncology Meeting 2006 Member of the European-Canadian Consensus Conference on the Treatment of Testicular Cancer 2006 Member of the organizing committee, First Canadian Consensus Conference on Testicular Cancer 2007 Member of the organizing committee, First Canadian Kidney Cancer Forum, January 2008 Speaker, Canadian Urology Association Annual Meeting 2008 Member Scientific Committee, 20th EORTC-NCI-AACR Symposium on “Molecular Targets and Cancer Therapeutics” October 2008 Member of the organizing committee, Second Canadian Kidney Cancer Forum, January 2009 10. SERVICE TO THE UNIVERSITY (a) Memberships on committees, including offices held and dates 9 The representative of the Dept. of Hematology/Medical Oncology in the Tuebingen University Faculty of Medicine Committee to develop hospital-wide guidelines for physician working hours in accordance with the European Community Labor Laws, 2002/2003 Member of the Committee to reorganize and optimize departmental structures and procedures, 1997/1998. Within a pilot project at Tuebingen University Hospital, the Dept. of Hematology/Medical Oncology was selected by the Hospital Administration to work in cooperation with an external consulting firm specializing in health care. The committee analyzed existing organizational structures, various areas of operations, related work processes and data management. Recommendations for improvement were made and subsequent implementation was supervised and reviewed. Member of the Committee involved in the construction of modular clinic wards and for the subsequent relocation of several Dept. of Hematology/Medical Oncology wards into these modules, 2001-2003. Due to modernization requirements, the Dept. of Hematology was almost completely renovated between 2001 and 2003 and therefore, in part temporarily and in part permanently, relocated within the University Hospital complex. In addition, the committee analyzed existing structures, forecasted future requirements and made recommendations to the superordinate University Building Development Committee One of the 3 physicians, chosen to develop standardized chemotherapy treatment protocols and pre-printed chemotherapy orders for the University of Tuebingen Dept. of Hematology / Oncology, 2001. Co-Chair, Clinical Research Unit for Genitourinary and Phase I Clinical Trials, BCCA since 6/2004 Head, Scientific Evaluation and Review Committee for Gastrointestinal Malignancies, BCCA since 6/2004 Member, Scientific Evaluation and Review Committee for Genitourinary Malignancies, BCCA since 9/2004 Member, National Cancer Institute of Canada Audit and Monitoring Committee, since 2006 Chairman, National Cancer Institute of Canada Disease oriented Group Testis Cancer since 2007 Co-Chair, National Cancer Institute of Canada Disease oriented Group Esophageal/Gastric Cancer since 2007 Member, National Cancer Institute US Esophago-Gastric Intergroup Task Force Group since 2007 (b) Other service, including dates Chief Resident / Fellow at the Dept. of Medicine II, University of Tuebingen, Germany 2001-2003 11. SERVICE TO THE COMMUNITY (a) Memberships on scholarly societies, including offices held and dates Member of the German College of Physicians since 1993 Member of the German Society of Hematology/Oncology since 1997 Member of the European Society of Medical Oncology since 1998 Member of the Working group “Medical Oncology” of the German Cancer Society since 2001 Member of the American Society of Clinical Oncology since 2004 (b) Memberships on other societies, including offices held and dates (c) Memberships on scholarly committees, including offices held and dates Member of the Consensus Group of the German Society of Hematology/Oncology for the development of 10 therapeutic recommendations for the treatment of solid tumors. Member of the „Abstract Reviewer“ group of the German Society of Hematology/Oncology for the Annual Meeting 1999. Member of the organizing committee and local organizer of the UICC-Meeting on Testicular Cancer, 1999. Member of the Interdisciplinary Work Group „Testicular Cancer“ of the German Cancer Society since 2000. Member of the „Abstract Reviewer“ group of the German Cancer Society for the Annual Meeting 2002 Member and secretary of the European Consensus Conference on the treatment of testicular cancer 2002/2003 Secretary of the German Cancer Congress 2004 of the German Society of Cancer Member of the organizing committee, First Canadian Consensus Conference on Testicular Cancer 2007 Member of the organizing committee, First Canadian Kidney Cancer Forum, January 2008 Member of the organizing committee, Second Canadian Kidney Cancer Forum, January 2009 Faculty, American Society of Clinical Oncology Genitourinary Symposium February 2009 Faculty, American Society of Clinical Oncology Annual Meeting May/June 2009 (d) Memberships on other committees, including offices held and dates Member, NCIC Audit and Monitoring Committee since 2006 Member / Co-Chair, NCIC Disease oriented Group Esophagus/Stomach 4/2007 Member / Chair NCIC Disease oriented Group Testis since 12/2007 (f) Reviewer (journal, agency, etc. including dates) Annals of Oncology Journal of Cancer Research And Clinical Oncology British Journal of Cancer American Journal of Cancer Onkologie Cancer Treatment Reviews Lancet Oncology Journal of Clinical Oncology Nature Clinical Practice Oncology Current Medical Literature British Journal of Urology Expert opinion on Investigational Drugs (g) External examiner (indicate universities and dates) (h) Consultant (indicate organization and dates) - Joint Oncology Drug Review / Ministry of Health Ontario 2008 11 (i) Other service to the community 12. AWARDS AND DISTINCTIONS (a) Awards for Teaching (indicate name of award, awarding organizations, date) (b) Awards for Scholarship (indicate name of award, awarding organizations, date) (c) Awards for Service (indicate name of award, awarding organizations, date) (d) Other Awards “Best abstract“: Annual meeting of the German Society of Hematology/Oncology 2001 13. OTHER RELEVANT INFORMATION (Maximum One Page) 12 University of British Columbia Publications Record Date: Initial: FIRST NAME: 1. SURNAME: Kollmannsberger MIDDLE NAME(S): June 6th 2008 CK Christian Kurt Publications 01. Refereed Publications (a) Journals 1. Bokemeyer C, Lampe CS, Clemens MR, Hartmann JT, Quietzsch D, Forkmann L, Kollmannsberger C, and Kanz L: A phase II trial of paclitaxel and weekly 24 h infusion of 5-fluorouracil/folinic acid in patients with advanced gastric cancer. Anticancer Drugs 8: 396-399, 1997. 2. Bokemeyer C, Berger CC, Hartmann JT, Kollmannsberger C, Schmoll HJ, Kuczyk MA, and Kanz L: Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer. Br J Cancer 77: 1355-1362, 1998. 3. Hartmann JT, Harstrick A, Daikeler T, Kollmannsberger C, Muller C, Seeber S, Kanz L, and Bokemeyer C: Phase II study of continuous 120 h infusion of mitomycin C as salvage chemotherapy in patients with progressive or rapidly recurrent colorectal cancer. Anticancer Drugs 9: 427-431, 1998. 4. Kollmannsberger C, Peters HD, and Fink U: Chemotherapy in advanced pancreatic adenocarcinoma. Cancer Treat.Rev. 24: 133-156, 1998. 5. Kollmannsberger C, Hartmann JT, Kanz L, and Bokemeyer C: Risk of secondary myeloid leukemia and myelodysplastic syndrome following standard-dose chemotherapy or high-dose chemotherapy with stem cell support in patients with potentially curable malignancies. J Cancer Res Clin Oncol 124: 207-214, 1998. * 6. Kollmannsberger C, Beyer J, Droz JP, Harstrick A, Hartmann JT, Biron P, Flechon A, Schoffski P, Kuczyk M, Schmoll HJ, Kanz L, and Bokemeyer C: Secondary leukemia following high cumulative doses of etoposide in patients treated for advanced germ cell tumors. J Clin Oncol 16: 3386-3391, 1998. 7. Bokemeyer C, Kollmannsberger C, Meisner C, Harstrick A, Beyer J, Metzner B, Hartmann JT, Schmoll HJ, Einhorn L, Kanz L, and Nichols C: First-line high-dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: A multivariate and matched-pair analysis. J Clin Oncol 17: 3450-3456, 1999. 8. Bokemeyer C, Kollmannsberger C, Harstrick A, Beyer J, Gerl A, Casper J, Metzner B, Hartmann JT, Schmoll HJ, and Kanz L: Treatment of patients with cisplatin-refractory testicular germ-cell cancer. German Testicular Cancer Study Group (GTCSG). Int J Cancer 83: 848-851, 1999. 9. Hartmann JT, Albrecht C, Schmoll HJ, Kuczyk MA, Kollmannsberger C, and Bokemeyer C: Long-term effects on sexual function and fertility after treatment of testicular cancer. Br J Cancer 80: 801-807, 1999. 13 10. Hartmann JT, Kollmannsberger C, Kanz L, and Bokemeyer C: Platinum organ toxicity and possible prevention in patients with testicular cancer. Int J Cancer 83: 866-869, 1999. 11. Hartmann JT, Quietzsch D, Daikeler T, Kollmannsberger C, Mayer F, Kanz L, and Bokemeyer C: Mitomycin C continuous infusion as salvage chemotherapy in pretreated patients with advanced gastric cancer. Anticancer Drugs 10: 729-733, 1999. 12. Kollmannsberger C, Brugger W, Hartmann JT, Maurer F, Bohm P, Kanz L, and Bokemeyer C: Phase II study of oral trofosfamide as palliative therapy in pretreated patients with metastatic soft-tissue sarcoma. Anticancer Drugs 10: 453-456, 1999. 13. Kollmannsberger C, Pressler H, Mayer F, Kanz L, and Bokemeyer C: Cisplatinrefractory, HER2/neuexpressing germ-cell cancer: induction of remission by the monoclonal antibody Trastuzumab [letter]. Ann Oncol 10: 1393-1394, 1999. 14. Kollmannsberger C, Hartmann JT, Kanz L, and Bokemeyer C: Therapy-related malignancies following treatment of germ cell cancer. Int J Cancer 83: 860-863, 1999. 15. Pereira PL, Schick F, Einsele H, Farnsworth CT, Kollmannsberger C, Mattke A, Duda SH, and Claussen C: MR-Tomographie von Knochenmarkveränderungen nach Hochdosis-Chemotherapie und autologer peripherer Stammzell-Transplantation [MR tomography of the bone marrow changes after high-dosage chemotherapy and autologous peripheral stem-cell transplantation]. Fortschr Röntgenstr 170: 251-257, 1999. 16. Kollmannsberger C, Gerl A, Schleucher N, Beyer J, Kuczyk M, Rick O, Casper J, Sosada M, Rie C, Kanz L, and Bokemeyer C: Phase II study of bendamustine in patients with relapsed or cisplatin-refractory germ cell cancer. Anticancer Drugs 11: 535-539, 2000. 17. Kollmannsberger C, Nichols C, Meisner C, Mayer F, Kanz L, and Bokemeyer C: Identification of prognostic subgroups among patients with metastatic 'IGCCCG poorprognosis' germ-cell cancer: an explorative analysis using cart modeling. Ann Oncol 11: 1115-1120, 2000. 18. Kollmannsberger C, Nichols C, Bamberg M, Hartmann JT, Schleucher N, Beyer J, Schoffski P, Derigs G, Ruther U, Bohlke I, Schmoll HJ, Kanz L, and Bokemeyer C: First-line high-dose chemotherapy +/- radiation therapy in patients with metastatic germ-cell cancer and brain metastases. Ann Oncol 11: 553-559, 2000. * 19. Kollmannsberger C, Quietzsch D, Haag C, Lingenfelser T, Schroeder M, Hartmann JT, Baronius W, Hempel V, Clemens M, Kanz L, and Bokemeyer C: A phase II study of paclitaxel, weekly, 24-hour continous infusion 5-fluorouracil, folinic acid and cisplatin in patients with advanced gastric cancer. Br J Cancer 83: 458-462, 2000. 20. Kollmannsberger C and Bokemeyer C: Therapy-related leukemia following high-dose chemotherapy: Compensating for the benefit? Onkologie 320: 480-482, 2000. 21. Dittmann H, Soekler M, Kollmannsberger C, Dohmen BM, Baumann C, Kopp A, Bares R, Claussen C, Kanz L, and Bokemeyer C: Comparison of 18FDG-PET with CT scans in the evaluation of patients with residual and recurrent Hodgkin's lymphoma. Oncol Rep 8: 1393-1399, 2001. 22. Kuczyk M, Bokemeyer C, Hartmann JT, Schubach J, Walter C, Machtens S, Knuchel R, Kollmannsberger C, Jonas U, and Serth J: Predictive value of altered p27Kip1 and p21WAF/Cip1 protein expression for the clinical prognosis of patients with localized prostate cancer. Oncol Rep 8: 1401-1407, 2001. 23. Machtens S, Serth J, Bokemeyer C, Bathke W, Minssen A, Kollmannsberger C, Hartmann J, Knuchel R, Kondo M, Jonas U, and Kuczyk M: Expression of the p53 and Maspin protein in primary prostate cancer: correlation with clinical features. Int J Cancer 95: 337-342, 2001. 14 24. Bokemeyer C, Kollmannsberger C, Oechsle K, Dohmen BM, Pfannenberg A, Claussen C, Bares R, and Kanz L: Early prediction of treatment response to high-dose salvage chemotherapy in patients with relapsed germ cell cancer using [18F]-FDG PET. Br J Cancer 86: 506-511, 2002. 25. Honecker F, Kollmannsberger C, Quietzsch D, Haag C, Schroeder M, Spott C, Hartmann JT, Baronius W, Hempel V, Kanz L, and Bokemeyer C: A phase II study of weekly paclitaxel, plus 24hour continuous infusion 5-fluorouracil, folinic acid and three weekly cisplatin for the treatment of patients with advanced gastric cancer. Anticancer Drugs 13: 497-503, 2002. * 26. Kollmannsberger C, Oechsle K, Dohmen BM, Pfannenberg A, Bares R, Claussen C, Kanz L, and Bokemeyer C: Prospective comparison of [18F]-FDG PET with conventional assessment by CT scans and serum tumor markers for the evaluation of residual masses in non-seminomatous germ cell cancer patients. Cancer 94: 2353-2362, 2002. 27. Kollmannsberger C, Rick O, Derigs G, Schleucher N, Schoeffski P, Beyer J, Schoch R, Sayer H-G, Gerl A, Kuczyk M, Spott C, Kanz L, and Bokemeyer C: Activity of oxaliplatin in patients with relapsed or cisplatinrefractory germ cell cancer: a study of the German Testicular Cancer Study Group (GTCSG). J Clin Oncol 20: 2031-2037, 2002. * 28. Kollmannsberger C, Mayer F, Pressler H, Koch S, Kanz L, Oosterhuis JW, Looijenga LHJ, and Bokemeyer C: Absence of c-KIT and members of the epidermal growth factor receptor family in refractory germ cell cancer. Cancer 95: 301-308, 2002. 29. Kollmannsberger C, Rick O, Klapproth J, Sayer H-G, Hentrich M, Welslau M, Spott C, Kanz L, and Bokemeyer C: Irinotecan in patients with relapsed or cisplatin refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group. Br J Cancer 87: 729-732, 2002. 30. Kuczyk M, Machtens S, Bokemeyer C, Kollmannsberger C, Hartmann JT, Kondo M, Merseburger A, and Jonas U: Surgical bladder preserving strategies in the treatment of muscle-invasive bladder cancer. World J Urol 20: 183-189, 2002. 31. Kuczyk M, Munch T, Machtens S, Bokemeyer C, Wefer A, Hartmann J, Kollmannsberger C, Kondo M, and Jonas U: The need for routine adrenalectomy during surgical treatment for renal cell cancer: the Hannover experience. BJU Int 89: 517-522, 2002. 32. Kuczyk M, Munch T, Bokemeyer C, Merseburger A, Wefer A, Kollmannsberger C, Kondoh M, Wegener G, Jonas U, Stenzl A: Is adrenalectomy an indispensable part of nephrectomy ? Results of a multivariate statistical analysis. Urologe A 42: 366-373, 2003 33. Meyer F, Kollmannsberger C, Bokemeyer C: Absence of c-Kit and members of the epidermal growth factor receptor famiily in refractory germ cell cancer [author reply]. Cancer 97: 1927-2928, 2003 34. Kollmannsberger C, Schleucher N, Rick O, Metzner B, Schoeffski P, Casper J, Sosada M, Schmoll HJ, Bohlke I, Meisner C, Kanz L, and Bokemeyer C: Analysis of salvage treatments for germ cell cancer patients who have relapsed after primary high-dose chemotherapy plus autologous stem cell support. Eur J Cancer 39: 775-782, 2003. 35. Bokemeyer C; Schleucher N; Metzner B; Thomas M; Rick O; Schmoll H-J; Kollmannsberger C; Boehlke I; Kanz L; Hartmann J-T: First-line sequential high-dose VIP chemotherapy with autologous transplantation for patients with primary mediastinal nonseminomatous germ cell tumours: a prospective trial. Br J Cancer 89: 29-35, 2003 36. Merseburger AS, Wegener G, Horstmann M, Oelke M, Zumbragel A, Bokemeyer C, Kollmannsberger C, Jonas U, Stenzl A, Kuczyk M.: Impact of tumor size on long-term survival of patients with organ-confined 15 renal cell cancer Aktuelle Urol 34: 469-474, 2003 37. Kollmannsberger C; Bokemeyer C: Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group (authors reply). Br J Cancer 89: 11411142, 2003 38. Ott K; Sendler A; Becker K; Dittler H-J; Helmberger H; Busch R; Kollmannsberger C; Siewert J-R; Fink U: Neoadjuvant chemotherapy with cisplatin, 5-FU, and leucovorin (PLF) in locally advanced gastric cancer: a prospective phase II study. Gastric Cancer 6: 159-67, 2003 39. Schmoll, H. J., Kollmannsberger, C., Metzner, B., Hartmann, J. T., Schleucher, Schleicher, J., Rick, O., Beyer, J., Hossfeld, D., Kanz, L., Berdel, W. E., Andreesen, R., Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin autologous stem cell support for patients with advanced metastatic germ cell cancer: an study of the German Testicular Cancer Study Group. J Clin Oncol, 21: 4083-4091, 2003. N., Schoeffski, P., and Bokemeyer, C. chemotherapy plus extended phase I/II * 40. Kollmannsberger, C., Beyer, J., Liersch, R., Schoeffski, P., Metzner, B., Rick, O., Hartmann, J. T., Stengele, K., Hohloch, K., Spott, C., Kanz, L., and Bokemeyer, C. Combination chemotherapy with gemcitabine plus oxaliplatin in patients with intensively pretreated or refractory germ cell cancer: a study of the German Testicular Cancer Study Group. J Clin Oncol, 22: 108-114, 2004. 41. Pfannenberg, A. C., Oechsle, K., Kollmannsberger, C., Dohmen, B. M., Bokemeyer, C., Bares, R., Vontheim, R., and Claussen, C. D. [Early prediction of treatment response to high-dose chemotherapy in patients with relapsed germ cell tumors using [18F]FDG-PET, CT or MRI, and tumor marker]. ROFOFortschritte auf dem Gebiet der Rontgenstrahlen und der Bildgebenden V, 176: 76-84, 2004. 42. Pfannenberg A. C., Oechsle K., Bokemeyer C., Kollmannsberger C., Dohmen B.M., Bares R., Hartmann J.T., Vonthein R., Claussen C.D. The role of [(18)F] FDG-PET, CT/MRI and tumor marker kinetics in the evaluation of postchemotherapy residual masses in metastatic germ cell tumors-prospects for management. World J Urol., 22:132-139, 2004 43. Kuczyk M., Bokemeyer C., Kollmannsberger C., Corvin S., Anastasiadis A., Machtens S., Merseburger A., Wegener G., Stenzl A., Hartmann J., Jonas U. Late relapse after treatment for nonseminomatous testicular germ cell tumors according to a single center-based experience. World J Urol, 22:55-59, 2004 44. Bokemeyer C., Kollmannsberger C., Stenning S., Hartmann J.T., Horwich A., Clemm C., Gerl A., Meisner C., Rueckerl C.P., Schmoll H.J., Kanz L., Oliver T.: Metastatic seminoma treated with either single agent carboplatin or cisplatin based combination chemotherapy: a pooled analysis of two randomized trials. Br J Cancer, 91:683-687, 2004. 45. Schmoll H.J., Souchon R., Krege S., Albers P., Beyer J., Kollmannsberger C., Fossa S.D., Skakkebaek N.E., de Wit R., Fizazi K., Droz J.P., Pizzocaro G., Daugaard G., de Mulder P.H., Horwich A., Oliver T., Huddart R., Rosti G., Paz Ares L., Pont O., Hartmann J.T., Aass N., Algaba F., Bamberg M., Bodrogi I., Bokemeyer C., Classen J., Clemm S., Culine S., de Wit M., Derigs H.G., Dieckmann K.P., Flasshove M., Garcia del Muro X., Gerl A., Germa-Lluch J.R., Hartmann M., Heidenreich A., Hoeltl W., Joffe J., Jones W., Kaiser G., Klepp O., Kliesch S., Kisbenedek L., Koehrmann K.U., Kuczyk M., Laguna M.P., Leiva O., Loy V., Mason M.D., Mead G.M., Mueller R.P., Nicolai N., Oosterhof G.O., Pottek T., Rick O., Schmidberger H., Sedlmayer F., Siegert W., Studer U., Tjulandin S., von der Maase H., Walz P., Weinknecht S., Weissbach L., Winter E., Wittekind C.; European Germ Cell Cancer Consensus Group. European consensus on diagnosis and treatment of germ cell cancer: a report of the European Germ Cell Cancer Consensus Group (EGCCCG). Ann Oncol. 16:172-173, 2005. 46. Wierecky J., Kollmannsberger C., Boehlke I., Kuczyk M., Schleicher J., Schleucher N., Metzner B., Kanz L., Hartmann JT., Bokemeyer C.: Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer. J Cancer Res Clin Oncol 131: 255-260, 2005 16 47. Dalal B.I., Kollmannsberger C.: Drug-induced haemolysis and methaemoglobinaemia in glucose 6phosphate dehydrogenase deficiency. Br J Haematol. 129:291, 2005 48. Kollmannsberger C., Budach W., Stahl M., Schleucher N., Hehr T., Wilke H., Schleicher J., Vanhoefer U., Jehle E.C., Oechsle K., Trarbach T., Boehlke I., Kanz L., Hartmann JT., Bokemeyer C.: Adjuvant chemoradiation using 5-fluorouracil/folinic acid/cisplatin with or without paclitaxel and radiation in patients with completely resected high-risk gastric cancer: two cooperative phase II studies of the AIO/ARO/ACO. Ann Oncol. 16:1326-33, 2005. 49. Al-Tourah AJ, Murray N, Coppin C, Kollmannsberger C, Man A, Chi KN.: Minimizing treatment without compromising cure with primary surveillance for clinical stage I embryonal predominant nonseminomatous testicular cancer: a population based analysis from British Columbia. J Urol. 174: 2209-13, 2005 50. Michels J., Montemurro T., Murray N., Kollmannsberger C., Nguyen K. Chi.: First- and second-line chemotherapy with docetaxel or mitoxantrone in patients with hormone-refractory prostate cancer: does sequence matter? Cancer. 106: 1041-1046, 2006 51. Kollmannsberger C., Nichols C., Bokemeyer C.: Recent advances in the management of patients with platinum-refractory germ cell tumors. Cancer 106:1217–26, 2006 52. McArthur HL., Dalal BI., Kollmannsberger C.: Intravascular hemolysis as a complication of clostridium perfringens sepsis. J Clin Oncol. 24: 2387-2388, 2006. 53. Kollmannsberger C., Schittenhelm M., Honecker F., Tillner J, Weber D., Oechsle K., Kanz L., Bokemeyer C.: A Phase I Study of the Humanized Monoclonal Anti–Epidermal Growth Factor Receptor (EGFR) Antibody EMD 72000 (Matuzumab) in Combination with Paclitaxel in Patients with EGFR-Positive Advanced Non– Small Cell Lung Cancer (NSCLC). Ann Oncol 17:1007-1013, 2006 54. Oechsle K, Honecker F, Kollmannsberger C, Rick O, Grunwald V, Mayer F, Hartmann JT, Bokemeyer C.: An open-label, multicenter phase II trial of capecitabine in patients with cisplatin-refractory or relapsed germ cell tumors. Anticancer Drugs. 18(3):273-6, 2007 55. Knox JJ, Hotte SJ, Kollmannsberger C, Winquist E, Fisher B, Eisenhauer EA.: Phase II study of Triapine in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161). Invest New Drugs. 2007 Mar 28; [Epub ahead of print] 56. Kollmannsberger C., Soulieres D., Wong R., Scalera A., Gaspo R., Bjarnason G.: Sunitinib in metastatic renal cell carcinoma: Recommendations for management of side-effects. CUAJ 1 (Suppl.2): 41-54, 2007 57. Lorch A, Kollmannsberger C, Hartmann JT, Metzner B, Schmidt-Wolf IG, Berdel WE, Weissinger F, Schleicher J, Egerer G, Haas A, Schirren R, Beyer J, Bokemeyer C, Rick O; German Testicular Cancer Study Group. Single versus sequential high-dose chemotherapy in patients with relapsed or refractory germ cell tumors: a prospective randomized multicenter trial of the German Testicular Cancer Study Group. J Clin Oncol 25: 2778-84, 2007. 58. Welz S, Hehr T, Kollmannsberger C, Bokemeyer C, Belka C, Budach W.: Renal toxicity of adjuvant chemoradiotherapy with cisplatin in gastric cancer. Int J Radiat Oncol Biol Phys. 69:1429-35, 2007. 59. Robinson A, Bainbridge T, Kollmannsberger C.: A spermatocytic seminoma with rhabdomyosarcoma transformation and extensive metastases. Am J Clin Oncol. 30: 440-441, 2007. 60. Bokemeyer C, Oechsle K, Honecker F, Mayer F, Hartmann JT, Waller CF, Böhlke I, Kollmannsberger C.: Combination chemotherapy with gemcitabine, oxaliplatin, and paclitaxel in patients with cisplatin-refractory or multiply relapsed germ-cell tumors: a study of the German Testicular Cancer Study Group. Ann Oncol. 19: 17 448-53, 2008 61. Krege S, Beyer J, Souchon R, Albers P, Albrecht W, Algaba F, Bamberg M, Bodrogi I, Bokemeyer C, Cavallin-Ståhl E, Classen J, Clemm C, Cohn-Cedermark G, Culine S, Daugaard G, De Mulder PH, De Santis M, de Wit M, de Wit R, Derigs HG, Dieckmann KP, Dieing A, Droz JP, Fenner M, Fizazi K, Flechon A, Fosså SD, Garcia Del Muro X, Gauler T, Geczi L, Gerl A, Germa-Lluch JR, Gillessen S, Hartmann JT, Hartmann M, Heidenreich A, Hoeltl W, Horwich A, Huddart R, Jewett M, Joffe J, Jones WG, Kisbenedek L, Klepp O, Kliesch S, Koehrmann KU, Kollmannsberger C, Kuczyk M, Laguna P, Leiva Galvis O, Loy V, Mason MD, Mead GM, Mueller R, Nichols C, Nicolai N, Oliver T, Ondrus D, Oosterhof GO, Paz-Ares L, Pizzocaro G, Pont J, Pottek T, Powles T, Rick O, Rosti G, Salvioni R, Scheiderbauer J, Schmelz HU, Schmidberger H, Schmoll HJ, Schrader M, Sedlmayer F, Skakkebaek NE, Sohaib A, Tjulandin S, Warde P, Weinknecht S, Weissbach L, Wittekind C, Winter E, Wood L, von der Maase H.: European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part I. Eur Urol. 53: 478-96, 2008. 62. Krege S, Beyer J, Souchon R, Albers P, Albrecht W, Algaba F, Bamberg M, Bodrogi I, Bokemeyer C, Cavallin-Ståhl E, Classen J, Clemm C, Cohn-Cedermark G, Culine S, Daugaard G, De Mulder PH, De Santis M, de Wit M, de Wit R, Derigs HG, Dieckmann KP, Dieing A, Droz JP, Fenner M, Fizazi K, Flechon A, Fosså SD, Garcia Del Muro X, Gauler T, Geczi L, Gerl A, Germa-Lluch JR, Gillessen S, Hartmann JT, Hartmann M, Heidenreich A, Hoeltl W, Horwich A, Huddart R, Jewett M, Joffe J, Jones WG, Kisbenedek L, Klepp O, Kliesch S, Koehrmann KU, Kollmannsberger C, Kuczyk M, Laguna P, Leiva Galvis O, Loy V, Mason MD, Mead GM, Mueller R, Nichols C, Nicolai N, Oliver T, Ondrus D, Oosterhof GO, Paz-Ares L, Pizzocaro G, Pont J, Pottek T, Powles T, Rick O, Rosti G, Salvioni R, Scheiderbauer J, Schmelz HU, Schmidberger H, Schmoll HJ, Schrader M, Sedlmayer F, Skakkebaek NE, Sohaib A, Tjulandin S, Warde P, Weinknecht S, Weissbach L, Wittekind C, Winter E, Wood L, von der Maase H.: European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part II. Eur Urol. 53: 497-513, 2008 63. Oechsle K, Kollmannsberger C, Honecker F, Boehlke I, Bokemeyer C: Cerebral metastases in nonseminomatous germ cell tumor patients undergoing primary high dose chemotherapy. Eur J Cancer : 44:1663-1669, 2008 64. Jewett MA, Knox JJ, Kollmannsberger C, Basiuk J.: Canadian kidney cancer forum 2008. Can Urol Assoc J. 2(3):183, 2008. 65. Chi KN, Siu LL, Hirte H, Hotte SJ, Knox J, Kollmannsberger C, Gleave M, Guns E, Powers J, Walsh W, Tu D, Eisenhauer E.: A phase I study of OGX-011, a 2'-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer. Clin Cancer Res. 14(3):833-839, 2008. 66. C. Kollmannsberger, F. Honecker, C. Bokemeyer: Pharmacotherapy of relapsed metastatic testicular cancer. Expert Op Pharmacother. 9:2259-2272, 2008 67. C. Kollmannsberger, C. Bokemeyer: Salvage chemotherapy after failure of first-line chemotherapy in patients with metastatic testicular cancer. Curr Opin Support Palliat Care, 2:167-172, 2008 68. Oechsle K, Bokemeyer C, Hartmann JT, Budach W, Trarbach T, Stahl M, Boehlke I, Kollmannsberger C.: Four consecutive multicenter phase II trials of adjuvant chemoradiation in patients with completely resected high-risk gastric cancer: the experience of the German AIO/ARO/CAO group. J Cancer Res Clin Oncol. 135:163-72, 2009 69. Heng DY, Chi KN, Murray N, Jin T, Garcia JA, Bukowski RM, Rini BI, Kollmannsberger C.: A populationbased study evaluating the impact of sunitinib on overall survival in the treatment of patients with metastatic renal cell cancer. Cancer. 115(4):776-783, 2009. 70. Schittenhelm M, Kollmannsberger C, Oechsle K, Harlow A, Town A, Honecker F, Weber D, Tillner J, Störkel S, Corless C, Wong K, Bokemeyer C, Heinrich M: Molecular determinants of response to Anti-EGFR 18 Matuzumab in combination with paclitaxel in patients with advanced non-small cell lung cancer. Molecular Cancer Therapeutics, e-pub anhead of print 71. Nichols CR, Kollmannsberger C: “Vox Populi: Using Community-Based Studies to Determine Best Management of Early-Stage Nonseminoma”. J Clin Oncol 2009” e-pub ahead of print 72. (b) Conference Proceedings (c) Other Abstracts (first author only) 1. Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer. (Poster) Annual Meeting of the German Society of Hematology/Oncology, Linz, 1997. 2. "FDG-PET for the evaluation of high-dose chemotherapy (HD-CTX) in patients with metastatic germ cell tumors (GCT)." (Oral presentation) 23rd Congress of the European Society of Medical Oncology, Athens Greece, 1998. 3. "A phase II trial of paclitaxel, cisplatin, and weekly 24h infusion of 5-fluorouracil (5-FU) / folinic acid in patients (pts) with advanced gastric cancer." (Poster) 23rd Congress of the European Society of Medical Oncology, Athens Greece, 1998. 4. "Secondary acute myeloid leukemia (S-AML) or myelodysplastic syndrome (S-MDS) following high-dose etoposide (>/= 2 g/m) containing chemotherapy in 302 patients with germ cell tumors (GCT)." (Poster) 34th Annual Meeting of the American Society of Clinical Oncology, Los Angeles USA, 1998. 5. First-line high-dose chemotherapy (HD-CT) +/- radiation therapy (RTX) in patients (pts) with CNS metatstases of non-seminomatous germ cell tumors (GCT). (Poster) 35th Annual Meeting of the American Society of Clinical Oncology, Atlanta USA, 1999. 6. "First-line high-dose chemotherapy with autologous stem cell transplantation versus standard-PEB/PEI for patients with poor prognosis germ cell cancer.". (Oral presentation) Annual Meeting of the German Society of Hematology/Oncology, Jena, 1999. 7. "Reduction of skin toxicity of pegylated liposomal doxorubicin (PLD) by concomitant administration of dexamethasone (DEX) and pyridoxin (PYR) in patients (pts) with antracycline-sensitive malignancies - a phase I/II trial.". (Poster) 25th Congress of the European Society of Medical Oncology, Hamburg, 2000. 8. A phase II study of paclitaxel, weekly 24-hour continuous infusion (CI) of 5-fluorouracil / folinic acid (FA) and cisplatin in patients (pts) with advanced gastric cancer. (Poster) 36th Annual Meeting of the American Society of Clinical Oncology, New Orleans USA, 2000. 9. "[18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) for the early prediction of response to high-dose chemotherapy (HD-CT) in patients (pts) with metastatic germ cell cancer.". (Poster) Annual Meeting of the German Society of Hematology/Oncology, Graz, 2000. 19 10. "Oxaliplatin in patients (pts) with cisplatin-refractory germ cell cancer (GCT).". (Poster) 37th Annual Meeting of the American Society of Clinical Oncology, San Francisco USA, 2001. 11. "Lack of overexpression of the EGF receptor family in refractory germ cell cancer (GCT).". (Oral presentation) Annual Meeting of the German Society of Hematology/Oncology, Mannheim, 2001 12. "Oxaliplatin (OX) in patients (pts) with relapsed or cisplatin refractory germ cell cancer (GCT). Final results of a German Testicular Cancer Study Group investigation.". (Oral presentation) Annual Meeting of the German Society of Hematology/Oncology, Mannheim, 2001. 13. Outcome of patients (pts) with "poor prognosis" germ cell cancer (GCT) relapsing after primary high-dose chemotherapy plus stem cell support (pHD/PBSCT). (Poster) 38th Annual Meeting of the American Society of Clinical Oncology, Orlando USA, 2002. 14. Epidermal growth factor receptor (EGFR) antibody EMD 72000 in combination with paclitaxel (P) in patients (pts) with EGFR-positive advanced non-small cell lung cancer (NSCLC): A phase-I study. (Poster discussion) 39th Annual Meeting of the American Society of Clinical Oncology, Chicago 2003 15. Adjuvant radiochemotherapy using 5-FU/Folinic acid/cisplatin Paclitaxel and radiation in patients with completely (R0) resected high-risk gastric cancer (UICC stages II-IV (M0): A phase II study of the AIO/ARO/ACO. (Oral presentation) Annual Meeting of the German Society of Hematology/Oncology, Basel, 2003. 16. Treatment of patients with relapsed of cisplatin-refractory germ cell cancer with a combination of gemcitabine and oxaliplatin: A phase II study of the German Testicular Cancer Study Group. (Oral presentation) Annual Meeting of the German Society of Hematology/Oncology, Basel, 2003. 17. Single agent carboplatin versus cisplatin based combination chemotherapy in patients with advanced seminoma: a meta-analysis of two European randomized trials. (Oral presentation) Annual Meeting of the German Society of Hematology/Oncology, Basel, 2003. 18. Gonadal late effects, fertility and sexual functioning in long-term survivors after high-dose chemotherapy with autologous stem cell transplantation (HD-CT) for testicular cancer. (Poster discussion) Annual meeting of the American Society of Clinical Oncology, New Orleans, 2004 19. A population-based study evaluating metastatic renal cell cancer (mRCC) patients treated with interferon (IFN) alone, first-line IFN then second-line sunitinib, or sunitinib alone. Annual Meeting of the American Society of Clinical Oncology, Chicago 2007 20. Phase I study of daily administration of MGCD265 to patients with advanced malignancies (Study 265-101), Annual Meeting of the American Society of Clinical Oncology, Orlando 2009 Presentations See above 02. Non Refereed Publications (a) Journals 1. Bokemeyer C, Kollmannsberger C, and Kanz L: The potential role of topotecan in the treatment of pediatric and adult soft-tissue sarcomas. Onkologie 21 (Suppl. 4): 124-127, 1998. 20 2. Jakob A, Kollmannsberger C, Kanz L, and Bokemeyer C: Spattoxizitat nach Chemotherapie maligner Hodentumoren. [Late toxicity after chemotherapy of malignant testicular tumors]. Urologe A 37: 635-647, 1998. 3. Bokemeyer C and Kollmannsberger C: UICC Symposium on Testicular Cancer, Tübingen 19./20 März 1999 (Kongreßbericht). Onkologie 22: 34-35, 1999. 4. Hartmann JT, Kuczyk MA, Kollmannsberger C, Kanz L, and Bokemeyer C: Future prospects in the chemotherapy of metastatic nonseminomatous testicular germ-cell cancer. World J Urol 17: 324-333, 1999. 5. Kollmannsberger C, Mross K, Jakob A, Kanz L, and Bokemeyer C: Topotecan – A novel topoisomerase I inhibitor: pharmacology and clinical experience. Oncology 56: 1-12, 1999. 6. Kollmannsberger C, Kuzcyk M, Mayer F, Hartmann JT, Kanz L, and Bokemeyer C: Late toxicity following curative treatment of testicular cancer. Semin Surg Oncol 17: 275-281, 1999. 7. Kollmannsberger C and Bokemeyer C: Behandlung des metastasierten Nierenzellkarzinoms (Journal Club). Onkologe 5: 824-825, 1999. 8. Barth-Kollmer C, Kollmannsberger C, and Bokemeyer C: Pamidronat zur Prävention osseärer Ereignisse (Journal Club). Onkologe 6: 587-589, 2000. 9. Bokemeyer C, Kollmannsberger C, Hartmann JT, and Kanz L: Follow up after primary treatment: curable diseases treated non-surgically. Ann Oncol 11 Suppl 373-8: 8, 2000. 10. Bokemeyer C, Kollmannsberger C, Oettle H, and Kanz L: Aktuelle Aspekte zur Chemotherapie von metastasierten Pankreas- und Gallenwegskarzinomen. [Current aspects of chemotherapy of metastatic pancreatic and biliary tract carcinomas]. Schweiz Rundsch Med Prax 89: 1545-1552, 2000. 11. Kollmannsberger C, Mayer F, Kuczyk M, Kanz L, and Bokemeyer C: Treatment of patients with metastatic germ cell tumors relapsing after high-dose chemotherapy. World J Urol 19: 120-125, 2001. 12. Kollmannsberger C and Bokemeyer C: Chemotherapie des metastasierten Blasenkarzinoms (Journal Club). Onkologe 7: 580-581, 2001. 13. Kollmannsberger C and Bokemeyer C: Adjuvante Chemotherapie bei Hochrisikoweichteilsarkomen der Extremitäten (Journal Club). Onkologe 7: 906-907, 2001. Patienten mit 14. Bokemeyer C, Hartmann JT, Kuczyk M, Truss MC, Kollmannsberger C, Beyer J, Jonas U, and Kanz L: Recent strategies for the use of paclitaxel in the treatment of urological malignancies. World J Urol 16: 155162, 2002. 15. Kollmannsberger C, Albers P, and Bokemeyer C: Chemotherapie des metastasierten Blasenkarzinoms [Chemotherapy of metastatic bladder cancer]. Onkologe 9: 950-961, 2002. 16. Kollmannsberger C, Budach W, and Bokemeyer C: Adjuvante Radiochemotherapie bei Patienten mit Hochrisikomagenkarzinom (Journal Club). Onkologe 8: 392-394, 2002. 17. Kollmannsberger C and Bokemeyer C: PEB ist nicht gleich PEB (Journal Club). Onkologe 8: 191-192, 2002. 18. Kollmannsberger C., Bokemeyer C.: Treatment of patients with good prognosis germ cell cancer. Onkologe 9: 980-984, 2003 19. Rick O, Kollmannsberger C, Hartmann JT, Braun T, Siegert W, Bokemeyer C, Beyer J.: The role of highdose chemotherapy in relapsed germ cell tumors. World J Urol. 22: 25-32, 2004 21 20. Kollmannsberger C., Gerber E., Budach W., Bokemeyer C.: Rolle der systemischen Therapie ± Radiotherapie beim resektablen Kardia-/Magenkarzinom [ Role of systemic treatment ± radiation in resectable cardia-/gastric adenocarcinoma]. Onkologe 11: 650-657, 2005 21. Kollmannsberger C, Honecker F, Bokemeyer C.: Treatment of germ cell tumors—update 2006. Ann Oncol 17 Suppl 10:x31-5, 2006 (b) Conference Proceedings Kollmannsberger C., Honecker F., Bokemeyer C.: Treatment of germ cell tumors – update 2006. ESMO Educational Book 2006 (c) Other 03. Books (a) Authored (b) Edited (c) Chapters 1. Kollmannsberger C and Fink U: Pankreaskarzinom [Pancreatic cancer]. In: Seeber S und Schütte J (Hrsg.): Therapiekonzepte Onkologie 3.Auflage. Springer-Verlag, Berlin, Heidelberg, New York 621-639, 1998 2. Bokemeyer C, Kollmannsberger C, Weiß J, and Schmoll H-J: Gonadale Toxizität und Infertilität [Gonadal toxicity and infertility]. In: Schmoll H-J, Hoeffken K, und Possinger K (Hrsg.): Kompendium Internistische Onkologie 2.Auflage. Springer-Verlag, Heidelberg - New York 1427-1440, 1999 3. Bokemeyer C, Kollmannsberger C, Weiß J, and Schmoll H-J: Teratogenität und Mutagenität [Teratogenicity and mutagenesis]. In: Schmoll H-J, Hoeffken K, und Possinger K (Hrsg.): Kompendium Internistische Onkologie 2.Auflage. Springer-Verlag, Heidelberg-New York 1441-1446, 1999 4. Bokemeyer C and Kollmannsberger C: Secondary malignancies. In: Lipp H-P (Hrsg.): Anticancer Drug Toxicity. Marcel Dekker Inc., New York 525-548, 1999 5. Bokemeyer C, Kollmannsberger C, Hartmann JT, and Kanz L: Einsatz von Paclitaxel in der Behandlung von malignen Keimzelltumoren des Hodens und von Urothelkarzinomen [Paclitaxel in the treatment of urological malignancies]. In: Hoeffken K, du Bois A, Kuehnle H, und Bokemeyer C (Hrsg.): Aktuelle Onkologie 102: Taxol-neue Daten zur Therapie solider Tumoren. Zuckschwerdt Verlag, München 90-102, 1999 6. Bokemeyer C, Hartmann JT, Kollmannsberger C, and Kanz L: Neue Entwicklungen in der Therapie urogenitaler Malignome [New developments in the treatment of urological malignancies]. In: du Bois A, Bokemeyer C, Gatzemeier U, Kreienberg R, und Kuehnle H (Hrsg.): Aktuelle Onkologie 107: Mit Taxol in der Therapie solider Tumoren ins nächste Jahrtausend. Zuckschwerdt Verlag, München 132-145, 1999 7. Bokemeyer C, Kollmannsberger C, Hartmann JT, Honecker F, Mayer F, and Kanz L: Aktuelle Entwicklungen in der Chemotherapie des Urothelkarzinoms [New developments in the chemotherapy of urothelial cancer]. 22 In: du Bois A, Bokemeyer C, Gatzemeier U, und Lück H-J (Hrsg.): Aktuelle Onkologie 111: Taxol - Aktuelle Aspekte in der Therapie solider Tumoren. Zuckschwerdt Verlag, München 87-95, 2001 8. Kollmannsberger C, Quietzsch D, Kanz L, and Bokemeyer C: Neue Entwicklungen in der Chemotherapie des Magenkarzinoms [New developments in the treatment of gastric cancer]. In: du Bois A, Bokemeyer C, Gatzemeier U, und Lück H-J (Hrsg.): Aktuelle Onkologie 111: Taxol - Aktuelle Aspekte in der Therapie solider Tumoren. Zuckschwerdt Verlag, München 96-105, 2001 9. Mitautor für: In: Deutsche Gesellschaft für Hämatologie und Onkologie (Hrsg.): Therapie-Empfehlungen der internistischen Onkologie – Solide Tumoren. Zuckschwerdt Verlag, München 2001 10. Bokemeyer C and Kollmannsberger C: Maligne Keimzelltumoren des Mannes [Malignant germ cell tumors]. In: Berdel/Böhm/Classen/Diehl/Kochsiek/Schmiegel (Hrsg.): Innere Medizin 5.Auflage. Urban & Fischer Verlag, München, 2003 11. Kollmannsberger C and Fink U: Pankreaskarzinom [Pancreatic cancer]. In: Seeber S und Schütte J (Hrsg.): Therapiekonzepte Onkologie 4.Auflage. Springer-Verlag, Berlin, Heidelberg, New York. 2003 12. Kollmannsberger C and Bokemeyer C: Gonadotoxizitaet after chemotherapy [Gonadal toxicity after chemotherapy]. In: Link H., Bokemeyer C., Feyer A.: Supportivtherapie, Deutscher Ärzte-Verlag GmbH, Koeln, 2004 13. Bokemeyer C, Kollmannsberger C: Secondary malignancies. Kompendium Internistische Onkologie. Springer-Verlag Heidelberg, Berlin, New York, 2006 04. Patents 05. Special Copyrights 06. Artistic Works, Performances, Designs 07. Other Works 08. Work Submitted 09. Work In Progress Management of Disseminated Non-seminomatous Germ Cell Tumors with Risk-Based Chemotherapy followed by Response Guided Post-Chemotherapy Surgery – Cooperation with Health Science University, Oregon. Surveillance as primary treatment strategy for stage I nonseminoma patients – Cooperation with Health Science University, Oregon Outcome of stage I seminoma patients treated with active surveillance – Cooperation with Health Science University, Oregon Prognostic factors in stage I nonseminoma – Cooperation with Erasmus University Rotterdam, The Netherlands Sunitinib as palliative treatment for cisplatin-refractory germ cell cancer – a phase II study ABT-869 as salvage treatment for patients with metastatic RCC and failure of first line sunitinib therapy – a phase II study 23 Outcome of patients with curatively resected gastric and GE junction tumors in BC – retrospective review of BC patients Local principal investigator in several phase I, II and III studies 24