AP/CU Succeed Course Syllabus 2011-2012 School Year Course Title: AP/CU Succeed Biology Room: B-111 Introduction to General Biology I and II 2051/2061 and Introduction to General Biology Lab I and II 2071/2081 Instructor: Kristin Donley Credits: MHS (10/year); CU (3 Lecture; 1 Lab per semester); AP (exam score) Office Hours: by appointment Office: B-107 Email: Kristin.donley@bvsd.org Web site: http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.as px Designated Grade Levels: 11th and higher Course Duration: 2 semesters (Aug 16- May 30) Prerequisite/Recommendation: Biology and Chemistry or equivalent; geometry/algebra II Class Materials/Supplies: 1. 2. 3. 4. 5. 6. 7. Composition book (graph paper format) and either folder or 3-ring binder Calculator and ruler Black or blue pens, pencils, paper Google email account (can link other accounts) Goggles (will use throughout high school and college) $25 laboratory fee Optional, but Highly recommended-$20 for AP Study/Review Guide (Preparing for the Biology AP Exam; 8th Ed. Pearson Benjamin Cummings; ISBN 0-8053-7187-7) or your choice 8. Flash drive Course Descriptions: Monarch High: In AP Biology you will study concepts of general biology at a rigorous college level. Fundamental principles of each of the major biological fields will be covered in more depth and breadth than in high school biology. Throughout the units taught in class there will be an emphasis on 8 themes: 1) Science as a Process; 2) Evolution (change over time); 3) Energy Transfer; 4) Continuity and Change; 5) Relationships of Structure to Function; 6) Regulation; 7) Interdependence in Nature; 8) Science, Technology, and Society. Change over time (Evolution) is emphasized throughout the course and is the cornerstone or foundation of biology. As most colleges require a laboratory course be taken concurrently with the lecture, the AP Biology Lab is intended to extend your laboratory skills and provide laboratory experiences that improve your understanding of the class. Additionally, all students must have a separate spiral or composition book to be used as a Journal. The journal is used to respond to class presentations, speakers, articles, and webquests. This journal emphasizes application to the content you are learning and will help develop knowledge and critical thinking about ethical situations, environmental and social concerns. For example, topics such as eugenics, use of biotechnology, the peer review process/nature of science, human evolution debates and global issues will be covered. This journal will be graded in the “class activities” category. (See Figure 2 (end of syllabus) crossreferencing topics with the 8 AP themes) CU Succeed: BIOL 2051 - General Biology I Summer 2010 Registration BIOL 2051 Introduces four major areas of study: (1) the chemistry of biological systems; (2) the structure and function of the cell; (3) cellular energy transformations (photosynthesis and respiration); and (4) genetics (mitosis, meiosis, patterns of inheritance, molecular genetics). Note: Biology and health science (pre-med, pre-vet, pre-physical therapy, etc.) majors must also take the accompanying laboratory - BIOL 2071. Prereq: CHEM 1000 or high school chemistry required. Semester Hours: 3 to 3 GT Pathways Category Key: GT-SC1 Registration is changing. Visit our website for details ucdenver.edu/registration. BIOL 2061 - General Biology II Summer 2010 Registration BIOL 2061 This course is a continuation of BIOL 2051. Introduces four major areas of study: (1) evolution,(2) animal structure and function, (3) plant structure and function and (4) ecology. Note: Biology and health science (pre-med, pre-vet, nursing, etc.) majors must also take the accompanying laboratory - BIOL 2081. Prereq: BIOL 2051 or equivalent with a grade of “C” (2.0) or higher. Semester Hours: 3 to 3 GT Pathways Category Key: GT-SC1 Registration is changing. Visit our website for details ucdenver.edu/registration. BIOL 2071 - General Biology Laboratory I Summer 2010 Registration BIOL 2071 Introduces the basic scientific approach and report preparation through exercises and experiments in cell biology, basic biochemical techniques, genetics, molecular genetics and applications of biotechnology. Note: Exercises corresponding to topics in BIOL 2051. Coreq: BIOL 2051. Semester Hours: 1 to 1 GT Pathways Category Key: GT-SC1 Registration is changing. Visit our website for details ucdenver.edu/registration. BIOL 2081 - General Biology Laboratory II Summer 2010 Registration BIOL 2081 Study of evolution, plant and animal anatomy, developmental biology; includes two off- campus ecology field trips. Note: Exercises corresponding to topics in BIOL 2061. Prereq: BIOL 2071 or equivalent with a grade of “C” (2.0) or higher; Coreq: BIOL 2061. Semester Hours: 1 to 1 GT Pathways Category Key: GT-SC1 Registration is changing. Visit our website for details ucdenver.edu/registration. Instructional Strategies: Students will be exposed to a variety of teaching pedagogies such as demonstrations, lectures, inquiry laboratory experiments, skill worksheets, class debates, field trips, guest presenters, literature reviews, tests, and Eistruction clickers, Interwrite boards, Internet, and 3D computer technology. Process skills in scientific reading and writing, listening, following directions, hypothesizing, observing, recording, evaluating, analyzing data, and cooperating with others will be emphasized throughout the course. Learning Materials: Campbell, Reece, Mitchell, Biology, 8th edition, Benjamin/Cummings and Addison Wesley, 2009. I will check out a book to you. You should take this home or to wherever you do your reading and studying. We have extra older editions for classroom/school use to be checked out separately. If you would like your own personal text, you can easily find them through a university bookstore or several on-line sites. (Note: Just make sure you buy the 8th edition…there are significant updates with this edition!) I will also provide various supplemental handouts (e.g., articles from Time, Scientific American and Discover) and vodcasts during the year and you will be required to purchase the accompanying study guide (Preparing for the Biology AP Exam; 8th Ed. Pearson Benjamin Cummings; ISBN 0-8053-7187-7). Assessment: There are two separate grades for the CU courses: the lecture grade and the laboratory grade. For your Monarch transcript, your grade will be a weighted average between your lecture grade (70%) and your laboratory grade (30%). At Monarch, AP Biology is a GPA weighted course (see grade scale below). For college credit, you will have to register on-line (details provided later) and the lecture and laboratory grades will appear individually on your transcript from CU-Denver and AP College Board AP Biology Exam. Attendance while not directly computed into your grade, is extremely important, for absences will affect your ability to succeed in this course (see separate attendance policy below). Although it will vary significantly throughout the year, plan on spending an average of 30-45 minutes daily on biology work/studying. I will be giving you reading assignments and problem sets for each chapter/unit that we study. These assignments will often include notes, vocabulary, concept mastery problems and short essays as well as critical thinking problems. These study guides will provide you with what you are expected to know, understand, demonstrate and apply to attain mastery of the unit’s objectives. Use your resources wisely! Also, all laboratory activities will have a lab report. The extensiveness of these reports will vary. You will be provided details/rubric for each lab on each lab day. Additionally, I will assign a couple of projects during the year. Details of each project and their grading scale will be distributed at the appropriate time. Class Grading Categories: Grades will be based on attainment of the essential learnings for each standard. Laboratory Work (Formative) Tests and Quizzes (Summative) Final Exam (Summative) Homework/Class Activities (Prep and Practice) Grade Scale: ~30% ~40% ~20% ~10% Letter Grade A B C D F Percentage GPA Scale Rubric Score 90 – 100% 5 10 A- (9093%) 11 A (94-97%) 12 A+ (98100%) 80 – 89% 4 7 B- (8083%) 8 B (8487%) 9 B+ (8889%) 70 – 79% 3 4 C- (7073%) 5C (74-77%) 6 C+ (7879%) 60 – 69% 2 1 D- (6063%) 2D (64-67%) 3 D+ (6869%) Below 60% 1 0 F (BELOW A 60%) Class Rules: Academic Honor Code: (This is a biggie!) You are to submit only your own work manufactured from your own thoughts and processes. Anything used from another source must be appropriately cited! Students failing to comply with the “honor code” are subject to disciplinary action through the instructor, Monarch’s administration, and CU-Denver’s Board of Student Affairs. No warning is necessary from the instructor. Please note that your signature on the class contract indicates your awareness and acceptance of this policy. Classroom Conduct: At all times, conduct yourself in a manner that promotes learning and ensures safety. Treat yourself, your classmates, and your classroom with compassion and respect. Safety in the lab is essential! Unsafe practices or behavior of any kind will result in suspension from the lab and loss of credit. (See separate handout of Lab Safety Guidelines for further clarification.) Absent Policy: Work is to be turned in on its due date, even if you attend school for only part of the day. For an excused absence (from the entire day), it is your responsibility to obtain missed materials, notes, handouts, etc. and make up assignments within two days. Anything assigned prior to the excused day, is your responsibility to make sure it gets turned in on time! For work missed during that day, you have two days from the day of your return to see me about scheduling make-up labs, projects, quizzes, or tests; otherwise these assignments will become a zero. I highly suggest if you know about a scheduled absence that you make arrangements prior to missing class! Because of the fast pace and rigor of this class, I also highly suggest that you attend all classes, for attendance will be to your benefit! Do not schedule dentist appointments, doctor’s appointments, etc. during class time to avoid missing valuable information! For unexcused absences, as per school policy, no credit can be given for assignments not turned in or activities done during that day of class. However, be aware that you are still responsible for the material. Remember that most late work will not be accepted for full credit! The Instructor considers this document a contract between the student and instructor. If you have any questions, please feel free to contact me via (Kristin.donley@bvsd.org ) or at (720-541-4200 x4205). Additionally, there is a class web site where grades and other class information can be obtained http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.aspx look forward to this year and getting to know both the students and their parents/guardians. I Course Objectives/Outline *Notes: Some Ecology concepts are covered in the Evolution unit; if you plan on taking the AP Exam, please come to required study sessions and study on your own Biology (Campbell), Chapters 50-55. Separate labs and activities must be completed. Calendar can be found on: http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONL EY/Pages/default.aspx Go to “Lists” link on left; See Calendar Documents Link from above web site has lecture notes, some PowerPoints and Labs, study links, and students projects and vodcasts Some labs, handouts, activities and PowerPoints are taken from www.explorebiology.com and http://portal.mypearson.com/mypearson-login.jsp (Campbell Eighth Edition textbook and Lab Bench On-Line) (login:donleyapbio; password: apbiob111) and the AP wet Lab teacher/student manual All students are required to buy: “Preparing For the Biology- AP Exam Review Guide,” Campbell/Reece; In that, guide as well as throughout the units taught in class there will be an emphasis on 8 themes: 1) Science as a Process; 2) Evolution (change over time); 3) Energy Transfer; 4) Continuity and Change; 5) Relationships of Structure to Function; 6) Regulation; 7) Interdependence in Nature; 8) Science, Technology, and Society. Change over time (Evolution) is emphasized throughout the course and is the cornerstone or foundation of biology. (See Figure 2 at end of syllabus cross-referencing topics with the 8 AP themes) All students must have an email account via Google (gmail). The google account is used to collaboratively work on projects and labs, respond to class presentations, speakers, articles, and webquests, and practice AP essays. We will emphasies applications to the content you are learning and you will develop your knowledge and critical thinking skills about content, ethical situations, environmental and social concerns. For example, topics such as eugenics, use of biotechnology, the peer review process/nature of science, human evolution debates and global issues will be covered. Figure 1: Outline of course topics and activities/laboratory experiments First Semester (Aug. 16 – Jan 2) Activities/Laboratory Experiments Second Semester (Jan 2 – May 30) Chemistry of Life (Ch 1-6) 1. Water Essay http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.aspx) 2. PGLO Transformation Inquiry (BIORAD/AP Lab 6: Molecular Biology) http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.aspx) 3. Macromolecule Identification Lab http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.aspx) 4. Hemoglobin and Vitamin B-12 Chromatography Lab (BIORAD protocol) 5. Athletic Performance and Steroids Activity 6. Indicators and Macromolecules Lab (http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.aspx) 7. Pathogens Part 1 (Exploration of Bacteria, Viruses, Fungi, and Protists) Molecular Genetics (Ch 16-20) *Basic Chemistry *Water Chemistry *Organic Chemistry *Macromolecule Chemistry *Enzyme Chemistry Units of Life – Cells (Ch 7-8; 11-12) *Cell Structures and functions *Membrane Structure and function *Cellular Communication and Regulation *Cell Cycle and Mitosis Energy of Life – Energetics (Ch 9-10) *Energy Transfer *Coupled Reactions *Enzyme Kinetics *Fermentation *Cellular 1. Cell Variations Lab (Exploration of various live organisms and prepared slides: Campbell Lab) 2. Osmosis Inquiry Lab #1 (Diffusion and Osmosis AP Lab 1) 3. Osmosis Inquiry Lab #2 (opportunity to re-vise and re-run 1st experiment) 4. Cellpedia: Cell Structure and Function webquest (http://bvsd.org/SCHOOLS/MONARCHHIGH/TEACHERS/KDONLEY/Pages/default.aspx) 5. Cell Signaling Webquest 6. See Heredity of Life: Mitosis and Meiosis Labs (Mitosis/Meiosis AP Lab 3) 7. Pathogens Part 2 8. Cells and membrane transport essays 1. Enzyme Inquiry Lab (Enzyme Catalysis AP Lab 2 AND milk/lactaid w/ glucose strips Inquiry: www.explorebiology.com ) 2. Cellular Respiration Lab (Cell Respiration AP Lab 5 and Campbell on-line and http://www.ekcsk12.org/science/aplabreview/lab05.htm 3. Nutrition and Athletic Performance Activity #1 4. Photosynthesis Activity (chromatography: Photosynthesis AP Lab 4 and Campbell online) 5. Photosynthesis Activity (optional Campbell on-line Lab) 6. Pathogens Part 3 (www.microbeworld.org) 7. Mitochondria Genetics Lab (Pasco Labs) *DNA and RNA *Transcription, Translation, & Mutation *Microbial Genetics *DNA Technology and Application Evolution (Ch 22-28) *Descent with Modification *Natural Selection *Population Genetics *Speciation *Phylogeny and Systematics *Origin of Life *Ecology Applications (Ch 50-55) Plants (3539) *Plant Diversity *Structure, Growth, and Control *Transport and Nutrition *Reproduction and Development Respiration *Photosynthesis 8. Metabolism essays Heredity of Life – Genetics (Ch 13-15) 1. Mitosis and Meiosis web Lab (http://biog-101-104.bio.cornell.edu/BioG101_104/tutorials/cell_division.html) 2. Onion and Whitefish Cell Division Lab (Mitosis/Meiosis AP Lab 3) 3. Genetic Disorders Project 4. Dragon, Fruitflies, and Butterflies Genetics Lab (Either--Genetics and Organisms: AP Lab7 or http://www2.edc.org/weblabs/WebLabDirectory1.html; Biology Logal (now Biology Place) and http://genscope.concord.org/ ) 5. Genes in a Bottle: DNA Extraction (BIORAD protocol) 6. Mendelian Genetics Problems: Parts 1 & 2 7. Chi-Squared Lab Activity (written by Kim Foglia: www.explorebiology.com) 8. Planaria Regeneration Lab (HHMI) 9. Pathogens Part 4 10. Heredity Essays *Mitosis, Meiosis and Cell Cycle *Mendelian Genetics *Chromosomes and Abnormalities Animals (Ch 40-49) *Animal Diversity *Animal Structure and Function *Control Systems *Central Systems *Developing Systems Figure 2: The following is a chart that shows how the content is integrated with the 8 AP themes. Each box gives a statement of a topic that is used to integrate the AP themes. Evolution, change over time is reinforced throughout all of the content areas. Science as a Process Evolution Energy Transfer Continuity and Change Relationships of Structure to Function Regulation Interdependence in Nature Chemistry of Life X-ray crystallography helps scientists determine the 3-D structure of proteins. Chemical evolution of the young Earth set the stage for the origin of life. Living systems rely on coupled exergonic and endergonic reactions. Enzyme active sites have a shape that specifically matches the shape of the substrate. In feedback inhibition, a metabolic pathway is switched off by its end product. Prokaryotes play essential roles in chemical cycling for plants and animals. Cells The discovery and early study of cells progress-ed with the invention and improvement of micro-scopes The matching machinery of all eukaryotic cilia provides evidence for a braod evolution-ary connection among eukaryotes ATP powers cellular work DNA molecules carry biological information from one generation to the next. Replicated DNA is packed in chromosomes that are separated at mitosis and meiosis. The folded, membranous organization of the mitochon-drion enhances the productivity of cellular respiration. Cellular Energetics The Calvin cycle and its intermedi-ate products were determined by using radioactive isotopes. According to endosymbiotic theory, mitochon-dria and chloroplasts are the ancestors of ancient indepen-dent bacteria. A proton gradient across membranes powers the synthesis of ATP in cells. Mitochondrial inheritance patterns are different than Mende-lian patterns of inheritance. They follow a maternal The arrangement of the electron transport chain components within the inner membrane of the mitochondria facilitates energy transfer during cellular respiration. Freshwater protists, such as paramecium, have contractile vacuoles that maintain water balance. With the controlled opening and closing of stomata, plants balance water loss with CO2 intake for photosynthesis. Cells in a multicellular organism are coordinated by various modes of cell-cell communication. Most of the ecosystems of the biosphere are powered by energy captured by chloroplasts and “burned” by mitochondria Science, Technology, and Society DNA microarrays or chips provide powerful assays to analyze gene expression. Advances in cancer research depend on progress in our basic understandding of how cells work. Ethanol produced from crops is used as a fuel additive. Beadle and Tatum developed the “one gene—one enzyme hypothesis” by using mutations as a tool to investigate metabolic pathways. The HersheyChase experi-ment used radioactive labels to determine that the genetic material in phages is DNA. Many quantitative traits display polygenetic inheritance patterns. Mitochondrial myopathy, a disorder that affects ATP production, is inherited in mtDNA. Genomes provide a written history to life. Extremophiles have a diversity of energy metabolism; these unique metabolic pathways are rich areas of study. Evolutionary Biology Reznick and Endler designed experi-ments that demonstrated natural selection in wild populations of guppies. Natural selection is the mechanism of evolu-tionary adaptation. Stromatolites provide evidence of the rise of photosynthetic organ- isms about 2.8 billion years ago. Diversity of Organisms Evolutionary theory itself evolves as new methods and data refine our view of phylogenetic relationships among organisms. Life on Earth shares a common history that is the basis of phyloge- nies. Plants transform the light energy from the sun into chemical energy stored in the bonds of carbohydrates. Structure and Recent work sug- gests Natural selection can The shape and stacks Heredity Molecular Genetics pattern. DNA molecules carry biological information from one generation to the next. Chromosomes are a marvel of packaging. Alleles can show different degrees of dominance and recessiveness in relation to each other. Interaction of genes and their environment produces the phenotype. DNA technology has provided new treatments for genetic diseases. The continuity of life depends on the inheritance of information encoded in the nucleotide sequences of DNA molecules. Evolution can be defined as a change in gene frequency. The structure of tRNA molecules fits their function as readers/translators of genetic code. Mutations that cause deficiencies in signaling pathways that regulate the cell cycle can lead to cancer. The universal genetic code makes genetic recornbination possible. Automatic DNA sequencing machines accelerated the completion of the Human Genome Project. The whale fossil record provides evidence of key structural adaptations for locomotion in an aquatic lifestyle. Peter and Rosemary Grant documented natural selection as finch populations in the Galapagos adapted to cyclical environmental changes. Molecular phylogenies are increaseingly important tools for identifying emergent diseases. Multicellular organisms have a diversity of life cycles. Some, such as mosses, have distinctly different generations that alternate between haploid and diploid stages. Samaras are winged Key adaptations, such as the amniotic egg, have enabled verte brates to colonize terrestrial environments. Diverse groups have adapted to hypotonic, fresh-water environments. The coevolution of flowering plants and their pollinators has created mutually dependent relationships such as the Yucca moth and the yucca plant. The symbiotic relationship of mycorrhizae and plants is vital to ecosystems. The honeycombed Countercurrent heat Consumers acquire Natural models such Destruction of tropical rain forests has led to a great loss of biodiversity. Function of Plants and Animals that some redwoods may be very near the limit for maximum height that water can be transport-ted by plant vascular systems. refine and fine tune adaptations such as wings. of grana in chloroplasts maxi- mize the collection of photon energy by photosystems. seeds that enhance seed dispersal in trees, such as the maples. construction of a bird’s bones pro vides a lightweight skeleton of great strength that makes flight possible. exchange between out-going and incoming blood vessels in whale flippers helps to conserve internal body temperature. Ecology Long-term ecolog- ical reserves are established to monitor critical ecosystems throughout North America. A very significant portion of Earth’s biodiversity is concentrated in just a few “hot spots.” Energy flows from sunlight to pro- ducers to consumers. Life cycles of species are adapted for different environments— “r-species” are often species of disturbed areas whereas “Kspecies” Predominate in stable ecosystems. Parasites have evolved adaptations that enhance their survival in their specific hosts. Life on Earth is dependent on biogeochemical nutrient cycles. their energy in chemical form by eating plants, by eating animals that ate plants, or by decomposing organic refuse. The energy that enters an ecosystem as sunlight exits as heat, which all organisms dissipate to their surrounding (entropy). as the wing structure of dragonflies can sometimes inform human engineering. Genetic engineering is used to improve certain species of bioremediators that detoxify polluted ecosystems.