DEPARTMENT OF PHYSIOLOGY and BIOPHYSICS Seminar Series Spring 2009 Sanger Hall, Room 2-020 Wednesday, at 12:00 p.m. January 14 Vijay Lyall, Ph.D., Department of Physiology and Biophysics, VCU School of Medicine (Host: Dr. De Felice) Title: TRPV1t: A Candidate Mammalian Salt Taste Receptor January 21 Edward W. Inscho, Ph.D., Department of Physiology, School of Medicine, Medical College of Georgia (Host: Dr. Pin-Lan Li) Title: Mechanisms of Renal Microvascular Dysfunction in Hypertension January 28 Sid Simon, Ph.D., Department of Neurobiology, Duke University (Host: Dr. Vijay Lyall) Title: The Gustatory System and Multisensory Integration February 4 Sarah Spiegel, Ph.D., Department of Biochemistry and Molecular Biology, VCU School of Medicine (Host: Dr. Diomedes Logothetis) Title: The Ins and Outs of Sphingosine-1-Phosphate February 11 Linda Boland, Ph.D., Department of Biology, University of Richmond (Host: Dr. Gea-Ny Tseng) Title: Polyunsaturated Fatty Acid Inhibition of Fast-Inactivation Potassium Channels February 18 Jason Rife, Ph.D., Department of Medicinal Chemistry, VCU School of Medicine (Host: Dr. Roland Pittman) Title: KsgA/Dim1 Methyltransferases: Ribosome Biogenesis One Methyl Group at a Time February 25 Douglas A. Bayliss, Ph.D., Department of Pharmacology, University of Virginia Health System (Host: Dr. Louis De Felice) Title: Regulation of Cellular Excitability by Modulation of Background Channels: Mechanisms and Physiological Roles March 4 No Seminar – Biophysical Society Meeting March 11 Spring Break March 18 Shanthi Srinivasan, M.D., Division of Digestive Disease, Emory School of Medicine, Emory University (Host; Dr. Murthy Karnam) Title: Role of Glial Derived Neurotrophic Factor (GDNF) in Diabetic Enteric Neuropathy March 25 Thirteenth Annual Ramsey Lecturer Evangelia G. Kranias, Ph.D., Department of Pharmacology and Cell Biophysics, University of Cincinnati (Host: Dr. Joseph Feher) Title: Targeting Calcium Cycling as a Therapeutic Modality in Heart Failure April 1 Ming-Ming Zhou, Ph.D., Department of Structural & Chemical Biology, Mount Sinai School of Medicine (Host: Dr. Diomedes Logothetis) Title: Modulating the Modulator: Epigenetic Control Beyond the Histone Code April 8 Antonio Abbate, M.D., Department of Internal Medicine, Division of Cardiology, VCU Medical Center (Host: Dr. Fadi Salloum) Title: Interleukin-1 and Post-Infarction Cardiac Remodeling April 15 Cancelled Iban Ubarretxena, Ph.D., Department of Structural and Chemical Biology, Mount Sinai School of Medicine (Host: Dr. Diomedes Logothetis) Title: Structural Studies on the Mechanism of Beta-Amyloid Peptide Production by Gamma-Secretase April 22 Cancelled Stuart Sealfon, M.D., Department of Neurology, Mount Sinai School of Medicine (Host: Dr. Logothetis) Title: The Glutamate-Serotonin Receptor Complex in Psychedelics and Schizophrenia April 29 Brian Duling, Ph.D., Department of Molecular Physiology and Biophysical Science and Biomedical Engineering, University of Virginia (Host: Dr. Helena Carvalho) Title: A Role for Voltage Gated Channels in Endothelial Cell Signaling May 6 Paul M. Wassarman, Ph.D., Department of Developmental & Regenerative Biology, Mount Sinai School of Medicine (Host: Dr. Diomedes Logothetis) Title: The Egg's Zona Pellucida and Mammalian Fertilization May 13 Sergei Noskov, Ph.D., Institute for Biocomplexity and Informatics, Department of Biological Sciences, University of Calgary (Host: Dr. Louis De Felice) Title: Computational Models of Channels and Transporter Function Please Note: The following seminars will be given in Sanger Hall, Room 3-016 May 20 Michael Caterina, Ph.D., Department of Biological Chemistry, Center for Sensory Biology, Johns Hopkins University (Host: Dr. Scott Ramsey) Title: TBA May 27 Twentieth Annual Distinguished Lecturer Wayne Hendrickson, Ph.D., Department of Pharmacology, Columbia University (Host: Dr. Qinglian Liu) Title: Transduction of Biochemical Signals Across Cell Membranes June 3 Steven A. Siegelbaum, Ph.D., Department of Neuroscience, Columbia University, Howard Hughes Medical Institute (Host: Dr. Lei Zhou) Title: Regulating Memory Storage Through Dendritic Integration June 10 Kenton Swartz, Ph.D., NIH/NINDS (Host: Dr. I. Scott Ramsey) Title: Structural Basis of Voltage Sensor Function and Pharmacology in Voltage-Activated Ion Channels June 17 Alfred L George, Jr., M.D., Division of Genetic Medicine, Vanderbilt University (Host: Dr. Gea-Ny Tseng) Title: Structure and Function of KCNE Potassium Channel Accessory Subunits June 24 Fred S. Lamb, M.D., Ph.D., University of Iowa Children’s Hospital, Department of Pediatrics (Host: Dr. Clive Baumgarten) Title: Distinct Intracellular and Extracellular Pathways of Nox1-dependent IC1 swell Activation: Novel Targets for the Selective Control of Inflammatory Nox Signaling