Lodovico Balducci, MD
Lodovico Balducci, MD
Faculty Rank:
Senior Member
Titles:
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Division Chief, Senior Adult Oncology
Department/Program Affiliations:
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Health Outcomes & Behavior
Gastrointestinal Tumor
Senior Adult Oncology
Hematologic Malignancies
Genitourinary Oncology
Breast
Education & Training:
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M.D., Catholic University, Roma, Italy, 1968
Fellowship, A. Gemelli General Hospital, Roma, Italy, 1970
- Medicine
Residency, University of Mississippi Medical Center, 1976
- Medicine
Fellowship, University of Mississippi Medical Center, 1979
- Hematology/Oncology
General Board Certification:
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Internal Medicine
Internal Medicine
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Internal Medicine
SubSpecialty:
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Medical Oncology
Hematology
Geriatric Medicine
Research Interests:
The scientific scope of the Senior Adult Oncology Program, under
the direction of Dr. Balducci, has been patient assessment and
prediction of treatment-related toxicity. This has been the focus
of this group's research for several years, and this work has
resulted in numerous scientific presentations and publications.
The most important scientific findings of the group's research
have included the following:
Independence of comorbidity and functional status
Ability of comprehensive geriatric assessment to unearth
unsuspected conditions that interfere with antineoplastic
treatment
Prediction of benefits and risk of adjuvant chemotherapy for
breast cancer in women aged 70 years and older based on
functional status and comorbidity
Formulation of the MAX-2 index for prediction of chemotherapyrelated toxicityAssessment of quality of life in older cancer
patients
Treatment-related preferences in older patients based on risktaking profile
Treatment-related preferences in older patients based on national
origin
This main research focus has been interwoven with other
research areas, in particular decision analysis, health care
delivery, and clinical pharmacology. Ongoing studies include
cost-effectiveness of cancer prevention and cancer treatment,
enrollment of older individuals in phase II trials,
pharmacokinetics of docetaxel in patients aged 70 years and
older, and cognitive effects of chemotherapy in older patients.
Dr. Balducci is protocol chairman of the Geriatric Oncology
Consortium, which conducts nationwide clinical trials in older
individuals, and is chairman of the committee on guidelines for
the management of older individuals of the National
Comprehensive Cancer Network. He also is involved in
cooperative research related to anemia of aging through the
National Anemia Action Council.
Clinical Interests:
cancer in the elderly; treatment related toxicity; comprehensive
geratric assessment tool; independence of comorbidity and
functional status; risks and benefits of adjuvant chemotherapy in
older patients
Lodovico Balducci, MD
Publications:
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Balducci L, Tam-McDevitt J, Hauser R, Simon J. Long
overdue - phase II studies in older cancer patients: where
does the FDAstand. J Clin Oncol. 2008 Mar 10;26(8):13871388. Pubmed ID: 18323564
Balducci L. Journal of Clinical Oncology: the next 25
years. J Clin Oncol. 2008 Apr 1;26(10):e4. Pubmed ID:
18375885
Balducci L, Al-Halawani H, Charu V, Tam J, Shahin S,
Dreiling L, Ershler W. Elderly cancer patients receiving
chemotherapy benefit from first-cycle pegfilgrastim.
Oncologist. 2007 Dec;12(12):1416-1424. Pubmed ID:
18165618
Balducci L. Aging, frailty, and chemotherapy. Cancer
Control. 2007 Jan;14(1):7-12. Pubmed ID: 17242666
Balducci L. An overlooked problem: anemia in the elderly
patient with cancer. J Support Oncol. 2007 Mar;5(3):115116. Pubmed ID: 17410808
Balducci L. Commentary: Evidence profiles for breast
cancer: Benefit/Harms data based on the totality of
randomized evidence. Cancer Treat Rev. 2007 Feb;33(1)
Suppl :85-86. Pubmed ID: 17071005
Balducci L. Molecular insight in cancer treatment and
prevention. Int J Biochem Cell Biol. 2007 Mar 14; : . In
Press. Pubmed ID: 17531523
8.
Boccia R, Lillie T, Tomita D, Balducci L. The effectiveness
of darbepoetin alfa administered every 3 weeks on
hematologic outcomes and quality of life in older patients
with chemotherapy-induced anemia. Oncologist. 2007
May;12(5):584-593. Pubmed ID: 17522247
9. Crawford J, Althaus B, Armitage J, Balducci L, Bennett C,
Blayney D, Cataland S, Dale D, Demetri G, Erba H, Foran J,
Freifeld A, Heaney M, HtoyS, Kloth D, Lyman G,
Messersmith W, Michaud L, Miyata S, Robbins A,
TallmanMS, Vadhan-Raj S, Westervelt P, Wong M. Myeloid
growth factors guidelines. J Natl Compr Canc Netw. 2007
Feb 5(;5(2):188-202. Pubmed ID: 17335688
10. Kumar A, Soares H, Balducci L, Djulbegovic B. Treatment
tolerance and efficacy in geriatric oncology: a systematic
review of phase III randomized trials conducted by five
National Cancer Institute-sponsored cooperative groups. J
Clin Oncol. 2007 Apr 1;25(10):1272-1276. Pubmed ID:
17401017
11. Lichtman S, Balducci L, Aapro M. Geriatric oncology: a
field coming of age. J Clin Oncol. 2007 May
10;25(14):1821-1823. Pubmed ID: 17488979
12. Perkins E, Small B, Balducci L, Extermann M, Robb C,
Haley W. Individual differences in well-being in older breast
cancer survivors. Crit Rev Oncol Hematol. 2007
Apr;62(1):74-83. Pubmed ID: 17240157
13. Robb C, Haley W, Balducci L, Extermann M, Perkins E,
Small B, Mortimer J. Impact of breast cancer survivorship on
quality of life in older women. Crit Rev Oncol Hematol.
2007 Apr;62(1) Suppl : 84-91. Pubmed ID: 17188505
14. Tam-McDevitt J, Balducci L, Hauser R, Gura D,
Paraghamian A, Thomas H, Lichtman S. Has demand for
clinical trial participants outpaced supply? J Natl Cancer
Inst. 2007 Jan 3;99(1):86-87. Pubmed ID: 17202120
15. Balducci L, Ershler W, Krantz S. Anemia in the elderlyClinical findings and impact on health. Crit Rev Oncol
Hematol. 2006 May;58(2):156-165. Pubmed ID: 16387511
16. Balducci L. Management of cancer in the elderly.
Oncology (Williston Park). 2006 Feb;20(2):135143. Pubmed ID: 16562648
17. Balducci L. Management of chemotherapy-induced
neutropenia in the older cancer patient. Oncology (Williston
Park). 2006 Dec;20(14) Suppl 9:26-31.
18. Balducci L. Transfusion independence in patients with
myelodysplastic syndromes: impact on outcomes and
quality of life. Cancer. 2006 May;106(10) Suppl :20872094. Pubmed ID: 16607649
19. Smith T, Khatcheressian J, Lyman G, Ozer H, Armitage J,
Balducci L, Bennett C, Cantor S, Crawford J, Cross S,
Demetri G, Desch C, Pizzo P, Schiffer C, Schwartzberg L,
Somerfield M, Somlo G, Wade J, Wade J, Winn R, Wozniak A,
Wolff A. 2006 update of recommendations for the use of
white blood cell growth factors: an evidence-based clinical
practice guideline. J Clin Oncol. 2006 Jul;24(19):31873205. Pubmed ID: 16682719
20. Balducci L, Aapro M. Epidemiology of cancer and aging.
Cancer Treat Res. 2005;124:1-15. Pubmed ID: 15839188
21. Balducci L, Cohen H, Engstrom P, Ettinger D, Halter J,
Gordon L, Kiel K, Kneier A, Lim D, Petersdorf S, Rosenthal R,
Silliman R, Vose J, Walker M, Zachariah B. Senior adult
oncology clinical practice guidelines in oncology. J Natl
Compr Canc Netw. 2005 Jul;3(4):572-590. Pubmed ID:
16038647
22. Balducci L, Ershler W. Cancer and ageing: a nexus at
several levels. Nat Rev Cancer. 2005 Aug;5(8):655662. Pubmed ID: 16056261
23. Balducci L, Hardy C, Lyman G. Hemopoiesis and aging.
Cancer Treat Res. 2005;124:109-134. Pubmed ID:
15839193
24. Balducci L. Cancer chemotherapy in elderly cancer
patients. J Oncol Manag. 2005 Apr;14(2):35-38. Pubmed
ID: 16018197
25. Balducci L. Epidemiology of cancer and aging. J Oncol
Manag. 2005 Apr;14(2):47-50. Pubmed ID: 16018199
26. Balducci L. Guidelines for the management of the older
cancer patient. Cancer Treat Res. 2005;124:233256. Pubmed ID: 15839199
27. Balducci L. Prevention of cancer in the older person.
Cancer J. 2005 Nov;11(6):442-448. Pubmed ID: 16393478
28. Balducci L. Squaring the circle: adjuvant chemotherapy for
older women with breast cancer. J Gerontol A Biol Sci Med
Sci. 2005 Oct;60(9):1135-1136. Pubmed ID: 16183951
29. Beghe C, Balducci L. Biological basis of cancer in the older
person. Cancer Treat Res. 2005;124:189-221. Pubmed ID:
15839197
30. Carreca I, Balducci L, Extermann M. Cancer in the older
person. Cancer Treat Rev. 2005 Aug;31(5):380402. Pubmed ID: 15967582
31. Extermann M, Chen H, Booth-Jones M, Meyer J, Balducci L,
Jacobsen P. Pilot testing of the computerized cognitive test
Microcog in chemotherapy-treated older cancer patients.
Crit Rev Oncol Hematol. 2005 May;54(2):137-143. Pubmed
ID: 15843096
32. Gridelli C, Aapro M, Ardizzoni A, Balducci L, De Marinis F,
Kelly K, LeChevalier T, Manegold C, Perrone F, Rosell R,
Shepherd F, De Petris L, Di MaioM, Langer C. Treatment of
advanced non-small-cell lung cancer in the elderly: results
of an international expert panel. J Clin Oncol. 2005 May
1;23(13):3125-3137. Pubmed ID: 15860872
33. Mandelblatt J, Schechter C, Yabroff K, Lawrence W,
Dignam J, Extermann M, Fox S, Orosz G, Silliman R, Cullen
J, Balducci L. Toward optimal screening strategies for older
women. Costs, benefits, and harms of breast cancer
screening by age, biology, and health status. J Gen Intern
Med. 2005 Jun;20(6):487-496. Pubmed ID: 15987322
34. Balducci L, Repetto L. Increased risk of myelotoxicity in
elderly patients with non-Hodgkin lymphoma. Cancer.
2004;100(1):6-11. Pubmed ID: 14692018
35. Balducci L. Believing is seeing: a new parameter to study
cancer prevention and cancer treatment in older
individuals. Cancer. 2004;100(5):881-882. Pubmed ID:
14983480
36. Balducci L. Cost of cancer clinical trials in elderly patients.
Expert Opin Pharmacother. 2004;5(3):505-511. Pubmed ID:
15013919
37. Balducci L. Profile of Prof. Paul Calabresi. Oncologist.
2004;9(1):110. Pubmed ID: 14755021
38. Biganzoli L, Aapro M, Balducci L, Crivellari D, Minisini A,
Piccart M. Adjuvant therapy in elderly patients with breast
cancer. Clin Breast Cancer. 2004;5(3):188-195. Pubmed ID:
15335450
39. Donovan KA, Jacobsen PB, Andrykowski MA, Winters E,
Balducci L, Malik U, Kenady D, McGrath P. Course of fatigue
in women receiving chemotherapy and/or radiotherapy for
early stage breast cancer. J Pain Symptom Manag.
2004;28(4):373-380. Pubmed ID: 15471655
40. Extermann M, Meyer J, McGinnis M, Crocker T, Corcoran
M, Yoder J, Haley W, Chen H, Boulware D, Balducci L. A
comprehensive geriatric intervention detects multiple
problems in older breast cancer patients. Crit Rev Oncol
Hematol. 2004;49(1):69-75. Pubmed ID: 14734156
41. Knight K, Wade S, Balducci L. Prevalence and outcomes of
anemia in cancer: a systematic review of the literature. Am J
Med. 2004;116: 11S-26S. Pubmed ID: 15050883
42. Kumar N, Allen K, Riccardi D, Bercu B, Cantor A, Minton S,
Balducci L, Jacobsen P. Fatigue, weight gain, lethargy and
amenorrhea in breast cancer patients on chemotherapy: is
subclinical hypothyroidism the culprit. Breast Cancer Res
Treat. 2004;83(2):149-159. Pubmed ID: 14997046
43. Luciani A, Balducci L. Multiple primary malignancies.
Semin Oncol. 2004;31(2):264-273. Pubmed ID: 15112155
44. Martoni A, Cucinotta D, Balducci L. Meeting report: Breast
cancer in the older woman. Tumori. 2004;90(4):437445. Pubmed ID: 15510992
45. Balducci L, Carreca I. Supportive care of the older cancer
patient. Crit Rev Oncol Hematol. 2003;48:S65-S70. Pubmed
ID: 14563523
46. Balducci L, Extermann M. Issues in the care of the older
cancer patient: delayed diagnosis, inadequate treatment,
and information gaps. In: The older cancer patient. New
York, NY: Springer Publishing Company Inc; 2003;24-44.
47. Balducci L, Extermann M. The cost of cancer prevention
and treatment in the older person. In: The older cancer
patient. New York, NY: Springer Publishing Company Inc;
2003;284-296.
48. Balducci L. Anemia, cancer, and aging. Cancer Control.
2003;10(6):478-486. Pubmed ID: 14652524
49. Balducci L. Epidemiology of anemia in the elderly:
information on diagnostic evaluation. J Am Geriatr Soc.
2003;51: 2-9. Pubmed ID: 12588565
50. Balducci L. Geriatric oncology. Crit Rev Oncol Hematol.
2003;46(3):211-220. Pubmed ID: 12791420
51. Balducci L. Lung cancer in the elderly: so many patients,
so little time. CA Cancer J Clin. 2003;53:322-324. Pubmed
ID: 15224972
52. Balducci L. Management of cancer pain in geriatric
patients. J Support Oncol. 2003;1(3):175-191. Pubmed ID:
15334874
53. Balducci L. Myelosuppression and its consequences in
elderly patients with cancer. Oncology (Williston Park).
2003;17: 27-32. Pubmed ID: 14682116
54. Balducci L. New paradigms for treating elderly patients
with cancer: the comprehensive geriatric assessment and
guidelines for supportive care. J Support Oncol. 2003;1(4)
Suppl 2:30-37. Pubmed ID: 15346998
55. Balducci L. The elderly patient with cancer: new
approaches for improved outcomes. J Support Oncol.
2003;1(4) Suppl 2:3-4. Pubmed ID: 15346993
56. Chen H, Cantor A, Meyer J, Corcoran M, Grendys E,
Cavanaugh D, AntonekS, Camarata A, Haley W, Balducci L,
Extermann M. Can older cancer patients tolerate
chemotherapy? A prospective pilot study. Cancer.
2003;97(4):1107-1114. Pubmed ID: 12569613
57. Extermann M, Balducci L. Optimizing cancer care in the
elderly: progress in geriatric oncology. Cancer Control.
2003;10(6):440-441. Pubmed ID: 14652519
58. Lyman G, Kuderer N, Agboola O, Balducci L. Evidencebased use of colony-stimulating factors in elderly cancer
patients. Cancer Control. 2003;10(6):487-499. Pubmed ID:
14652525
59. Repetto L, Carreca I, Maraninchi D, Aapro M, Calabresi P,
Balducci L. Use of growth factors in the elderly patient with
cancer: a report from the Second International Society for
Geriatric Oncology (SIOG) 2001 meeting. Crit Rev Oncol
Hematol. 2003;45(2):123-128. Pubmed ID: 12604125
60. Respini D, Jacobsen P, Thors C, Tralongo P, Balducci L.
The prevalence and correlates of fatigue in older cancer
patients. Crit Rev Oncol Hematol. 2003;47(3):273279. Pubmed ID: 12962901
61. Balducci L, Beghe C. Prevention of cancer in the older
person. Clin Geriatr Med. 2002;18(3):505-528. Pubmed ID:
12424870
62. Balducci L, Carreca I. The role of myelopoietic growth
factors in managing cancer in the elderly. Drugs. 2002;62:
47-63. Pubmed ID: 12479594
63. Balducci L. The clinical impact of cancer in the old-aged
person. Tumori. 2002;88(1) Suppl 1:S47-S48. Pubmed ID:
11989923
64. Extermann M, Chen H, Cantor A, Corcoran M, Meyer J,
Grendys E, CavanaughD, Antonek S, Camarata A, Haley W,
Balducci L. Predictors of tolerance to chemotherapy in older
cancer patients: a prospective pilot study. Eur J Cancer.
2002;38(11):1466-1473. Pubmed ID: 12110492
65. Lyman G, Kuderer N, Balducci L. Cost-benefit analysis of
granulocyte colony-stimulating factor in the management of
elderly cancer patients. Curr Opin Hematol. 2002;9(3):207214. Pubmed ID: 11953666
66. Patterson S, Balducci L, Meyer R. The Book of Job: a
2,500-year-old current guide to the practice of oncology:
the nexus of medicine and spirituality. J Cancer Educ.
2002;17(4):237-240. Pubmed ID: 12556063
67. Patterson S, Balducci L, Pow-Sang J. Controversies
surrounding androgen deprivation for prostate cancer.
Cancer Control. 2002;9(4):315-325. Pubmed ID: 12228757
68. Repetto L, Balducci L. A case for geriatric oncology.
Lancet Oncol. 2002;3(5):289-297. Pubmed ID: 12067806
69. Balducci L, Beghe C. Cancer and age in the USA. Crit Rev
Oncol Hematol. 2001;37(2):137-145. Pubmed ID:
11166587
70. Balducci L, Extermann M, Carreca I. Management of
breast cancer in the older woman. Cancer Control.
2001;8(5):431-441. Pubmed ID: 11579340
71. Balducci L, Extermann M. A practical approach to the
older patient with cancer: a review. Curr Probl Cancer.
2001;25(1):6-76. Pubmed ID: 11261937
72. Balducci L, Hardy C, Lyman G. Hematopoietic growth
factors in the older cancer patient. Curr Opin Hematol.
2001;8(3):170-187. Pubmed ID: 11303151
73. Balducci L, Lyman G. Patients aged > or = 70 are at high
risk for neutropenic infection and should receive
hemopoietic growth factors when treated with moderately
toxic chemotherapy. J Clin Oncol. 2001;19(5):15831585. Pubmed ID: 11230505
74. Balducci L, Meyer R. Spirituality and medicine: a proposal.
Cancer Control. 2001;8(4):368-376. Pubmed ID: 11483891
75. Balducci L. Cancer: an experiment education. Cancer
Control. 2001;8(2):192-196. Pubmed ID: 11326176
76. Balducci L. The geriatric cancer patient: equal benefit
from equal treatment. Cancer Control. 2001;8(2):125. Pubmed ID: 11326165
77. Overcash J, Extermann M, Parr J, Perry J, Balducci L.
Validity and reliability of the FACT-G scale for use in the
older person with cancer. Am J Clin Oncol. 2001;24(6):591596. Pubmed ID: 11801761
78. Balducci L, Beghe C. The application of the principles of
geriatrics to the management of the older person with
cancer. Crit Rev Oncol Hematol. 2000;35(3):147154. Pubmed ID: 10960797
79. Balducci L, Corcoran M. Antineoplastic chemotherapy of
the older cancer patient. Hematol Oncol Clin North Am.
2000;14(1):193-212. Pubmed ID: 10680078
80. Balducci L, Extermann M. Cancer and age. In: Haskell C,
ed. Cancer treatment. Philadelphia, PA: W.B. Saunders;
2000;435-451.
81. Balducci L, Extermann M. Cancer and aging. An evolving
panorama. Hematol Oncol Clin North Am. 2000;14(1):116. Pubmed ID: 10680068
82. Balducci L, Extermann M. Cancer, carcinogenesis and
aging. In: Rosenthal R, Zenilman M, Katlic M, et al, eds.
Principles and practice of geriatric surgery. New York, NY:
Springer Publishing Co Verlag; 2000;38-45.
83. Balducci L, Extermann M. Management of cancer in the
older person: a practical approach. Oncologist.
2000;5(3):224-237. Pubmed ID: 10884501
84. Balducci L, Extermann M. Management of the frail person
with advanced cancer. Crit Rev Oncol Hematol.
2000;33(2):143-148. Pubmed ID: 10737376
85. Balducci L, Hardy C, Lyman G. Hemopoietic reserve in the
older cancer patient: clinical and economic considerations.
Cancer Control. 2000;7(6):539-547. Pubmed ID: 11088062
86. Balducci L, Stanta G. Cancer in the frail patient. A coming
epidemic. Hematol Oncol Clin North Am. 2000;14(1):23550,xi. Pubmed ID: 10680080
87. Balducci L, Yates J. General guidelines for the
management of older patients with cancer. Oncology
(Williston Park). 2000;14(11A):221-227. Pubmed ID:
11195414
88. Balducci L. Cancer in the elderly: tailoring treatment.
Hosp Pract (Off Ed). 2000;35(3):73-80. Pubmed ID:
10737241
89. Balducci L. Evidence-based management of cancer in the
elderly. Cancer Control. 2000;7(4):368-376. Pubmed ID:
10895132
90. Balducci L. Geriatric oncology: challenges for the new
century. Eur J Cancer. 2000;36(14):1741-1754. Pubmed ID:
10974621
91. Balducci L. Inspiration from a forum arranged by
students. J Cancer Educ. 2000;15(4):245. Pubmed ID:
11199245
92. Broeckel J, Jacobsen P, Balducci L, Horton J, Lyman G.
Quality of life after adjuvant chemotherapy for breast
cancer. Breast Cancer Res Treat. 2000;62(2):141150. Pubmed ID: 11016752
93. Extermann M, Balducci L, Lyman G. What threshold for
adjuvant therapy in older breast cancer patients? J Clin
Oncol. 2000;18(8):1709-1717. Pubmed ID: 10764431
94. Kimmick G, Balducci L. Breast cancer and aging. Clinical
interactions. Hematol Oncol Clin North Am.
2000;14(1):213-234. Pubmed ID: 10680079
95. Mandelblatt J, Orosz G, Yabroff K, Extermann M, Lawrence
W, Yi B, Satariano W, Bloom H, Fox S, Silliman R, Fahs M,
Schecther C, Muenning P, Balducci L. Screening
mammography in elderly women. Research on Breast
Cancer in Older Women Consortium. JAMA.
2000;283(24):3202-3203. Pubmed ID: 10866863
96. Remick S, Sedransk N, Haase R, Craffey M, Subramanian
N, Dowlati A, Nazeer T, Ramnes C, Blanchard C, Martrianni
D, Balducci L, Horton J, Ruckdeschel J. Oral combination
chemotherapy in the management of AIDS-related
lymphoproliferative malignancies. Drugs. 2000;58(3):99107. Pubmed ID: 10711848
97. Zachariah B, Balducci L. Radiation therapy of the older
patient. Hematol Oncol Clin North Am. 2000;14(1):131167. Pubmed ID: 10680076
98. Balducci L, Beghe C. Pharmacology of chemotherapy in
the older cancer patient. Cancer Control. 1999;6(5):466470. Pubmed ID: 10758578
99. Balducci L, Cox C, Greenberg H, Lyman G, Miguel R, Karl
R, Fabri P. Management of cancer in the older person. In:
Complete geriatric oncology. London. Harwood Academic
Publishers; 1999;363-368.
100. Balducci L, Extermann M. Cancer in the elderly. Clin
Geriatr Med. 1999;6(13):51-58.
101. Balducci L, Hardy C. Aging, stress and anemia. Matur Med
Canada. 1999;82-85.
102. Balducci L. Mangement of cancer in the older person. Clin
Geriatr Med. 1999;7(5):89-97.
103. Jacobsen PB, Hann DM, Azzarello LM, Horton J, Balducci L,
Lyman GH. Fatigue in women receiving adjuvant
chemotherapy for breast cancer: characteristics, course,
and correlates. J Pain Symptom Manage. 1999
Oct;18(4):233-242. Pubmed ID: 10534963
104. Lyman G, Balducci L. Update on the economic analyses of
the use of the colony-stimulating factors. Curr Opin
Hematol. 1999;6(3):145-151. Pubmed ID: 10226734
105. Balducci L, Cox C, Greenberg H, Lyman G, Miguel R, Karl
R, Fabri P. Management of cancer in the older person. In:
Balducci L, Lyman G, Erschler W, et al, eds. Comprehensive
Geriatric Oncology. 2 ed. London. Harwood Academic
Publishers; 1998;363-368.
106. Balducci L, Extermann M. Difficulties in treating older
patients with cancer. Oncology Pract. 1998;15-18.
107. Balducci L, Hardy C. Anemia of aging: a model of
erythropoiesis in cancer patients. Cancer Control.
1998;5(2):17-21. Pubmed ID: 10762462
108. Balducci L, Lyman G, Erschler W. Management of cancer in
the older person. In: Balducci L, Lyman G, Erschler W, et al,
eds. Comprehensive Geriatric Oncology. London. Harwood
Academic Publishers; 1998;363-368.
109. Balducci L, Phillips D. Breast cancer in older women Am
Fam Physician. Am Fam Phys. 1998;58(5):11631172. Pubmed ID: 9787281
110. Balducci L, Silliman R, Baekey P. Breast cancer: a geriatric
perspective-part I. In: Balducci L, Lyman G, Ershler, et al,
eds. Comprehensive geriatric oncology. London. Harwood
Academic Publishers; 1998;629-660.
111. Benson K, Agosti S, Lyman G, Pow-Sang J, Saba H,
Balducci L. Estimated blood loss in group O as compared to
non-group O radical prostatectomy. Hematology.
1998;3:257-261.
112. Broeckel J, Jacobsen P, Horton J, Balducci L, Lyman G.
Characteristics and correlates of fatigue after adjuvant
therapy for breast cancer. J Clin Oncol. 1998;16(5):16891696. Pubmed ID: 9586880
113. Cova D, Beretta G, Balducci L. Cancer chemotherapy in the
older patient. In: Balducci L, Lyman G, Ershler W, et al, eds.
Comprehensive geriatric oncology. Amsterdam. Harwood
Academic Publishers; 1998;429-442.
114. Extermann M, Balducci L. Practical proposals for clinical
protocols in elderly patients with cancer. In: Balducci L,
Lyman G, Ershler W, et al, eds. Comprehensive Geriatric
Oncology. Amsterdam. Harwood Academic Publishers;
1998;263-269.
115. Extermann M, Overcash J, Lyman G, Parr J, Balducci L.
Comorbidity and functional status are independent in older
cancer patients. J Clin Oncol. 1998;16(4):15821587. Pubmed ID: 9552069
116. Lyman G, Kuderer N, Balducci L. Cancer care in the
elderly: cost and quality of life considerations. Cancer
Control. 1998;5:347-354. Pubmed ID: 10761085
117. Lyman G, Kuderer N, Balducci L. Economic impact of
granulopoiesis stimulating agents on the management of
febrile neutropenia. Curr Opin Oncol. 1998;10:291298. Pubmed ID: 9702395
118. Lyman G, Kuderer N, Greene J, Balducci L. The economics
of febrile neutropenia: implications for the use of colonystimulating factors. Eur J Cancer. 1998;34(12):18571864. Pubmed ID: 10023306
119. Lyman G, Lyman S, Kuderer N, Balducci L, Reintgen D,
Cox C. Menopausal status and breast cancer survival
following recurrence. Matur Med Canada. 1998;1:29-31.
120. Silliman R, Balducci L. Breast cancer: a geriatric
perspective-part II. In: Balducci L, Lyman G, Ershler W, et al,
eds. Comprehensive geriatric oncology. Amsterdam.
Harwood Academic Publishers; 1998;661-671.
121. Balducci L, Extermann M, Fentiman I, Monfardini S,
Perrone F. Should adjuvant chemotherapy be used to treat
breast cancer in elderly patients (> or = 70 years of age)?
Eur J Cancer. 1997;33:1720-1724. Pubmed ID: 9470824
122. Balducci L, Extermann M. Advances in cancer therapy for
the older patient. Intern Med. 1997;18:79-92.
123. Balducci L, Extermann M. Cancer chemotherapy in the
older person: what the medical oncologists needs to know.
Cancer. 1997;80:1317-1322. Pubmed ID: 9317185
124. Balducci L, Lyman G. Cancer in the elderly: epidemiologic
and clinical implications. Clin Geriatr Med. 1997;13:114. Pubmed ID: 8995097
125. Balducci L, Pow-Sang J, Friedland J, Diaz J. Cancer in the
elderly part II: prostate cancer. In: Balducci L, ed. Clinics in
geriatric medicine. Philadelphia, PA: Saunders; 1997;283306.
126. Balducci L, Trotti, III A. Organ preservation: an effective
and safe form of cancer treatment. Clin Geriatr Med.
1997;13(1):185-201. Pubmed ID: 8995107
127. Balducci L. Highlights of the third international
conference in geriatric oncology held in Tampa, Florida, 1315 November, 1996. Eur J Cancer. 1997;33(6):836-837.
128. Balducci L. Issues in the management of haematologic
malignancies. From the 26th Congress of the International
Society of Haematology (ISH), Signapore, 25-29 August
1996. Oncology Forum. 1997;1(1):12.
129. Kimmick G, Fleming R, Muss H, Balducci L. Cancer
chemotherapy in older adults: a tolerability perspective.
Drugs Aging. 1997;10(1):34-49. Pubmed ID: 9111706
130. Lyman G, Kuderer N, Lyman S, Debus M, Minton S,
Balducci L, Horton J, Reintgen D, Cox C. Menopausal status
and the impact of early recurrence on breast cancer
survival. Cancer Control. 1997;4(4):335-341. Pubmed ID:
10763039
131. Reintgen D, Joseph E, Lyman G, Yeatman T, Balducci L, Ku
N, Berman C, Shons A, Wells K, Horton J, Greenberg H,
Nicosia S, Clark R, Shivers S, Li W, Wang X, Cantor A, Cox C.
The role of selective lymphadenectomy in breast cancer.
Cancer Control. 1997;4(3):211-219. Pubmed ID: 10763020
132. Wells N, Balducci L. Geriatric Oncology Medical and
Psychosocial Perspectives. Cancer Practice. 1997;5(2):8791. Pubmed ID: 9110644
133. Zachariah B, Balducci L, Venkattaramanabalaji G, Casey L,
Greenberg H, DelRegato J. Radiotherpay for cancer patients
aged 80 and older: a study of effectiveness and side
effects. Int J Radiat Oncol Biol Phys. 1997;39(5):11251129. Pubmed ID: 9392554
134. Albertini J, Lyman G, Cox C, Yeatman T, Balducci L, Ku N,
Shivers S, Berman C, Wells K, Rapaport D, Shons A, Horton
J, Greenberg H, Nicosia S, Clark R, Cantor A, Reintgen D.
Lymphatic mapping and sentinel node biopsy in the patient
with breast cancer. JAMA. 1996;276(22):18181822. Pubmed ID: 8946902
135. Balducci L, Lyman G, Fabri P. Management of cancer in
the aged. Compr Ther. 1996;22(2):88-93. Pubmed ID:
8689868
136. Benson K, Balducci L, Milo K, Heckel L, Lyman G. Patient's
attitudes regarding out-of-hospital blood transfusion.
Transfusion. 1996;36:140-143. Pubmed ID: 8614964
137. Extermann M, Balducci L, Lyman G. Optimal duration of
adjuvant tamoxifen treatment in elderly breast cancer
patients: influence of age, cormorbidites, and various
effectiveness hypothesis on life-expectancy. Breast Dis.
1996;9:327-339.
138. Lyman G, Kuderer N, Balducci L, Horton J. Thresholds for
the use of recombinant human colony-stimulating factors
(CSFs) based on revised cost estimates incorporating
indirect medical, non-medical and intangible cost
considerations. Blood. 1996;88:346a.
139. Lyman G, Kuderer N, Balducci L. The decision to use
colony stimulating factors in patients receiving cancer
chemotherapy: quality of life adjustment. Proc Am Soc Clin
Oncol. 1996;15:535.
140. Lyman G, Lyman S, Balducci L, Kuderer N, Reintgen D,
Harris J, Cox C, Baekey P, Greenberg H, Horton J. Age and
the risk of recurrence in women with breast cancer. Cancer
Control. 1996;3:421-427. Pubmed ID: 10764500
141. Casey L, Zachariah B, Balducci L. Radiotherapy of the
oldest old cancer patients: a study of effectiveness and
toxicity. J Am Geriatr Soc. 1995;43:1-3.
142. Lyman G, Balducci L. A cost analysis of hematopoietic
colony-stimulating factors. Oncology. 1995;9:8591. Pubmed ID: 8608061
143. Robinson B, Balducci L. Breast lump in an 85-year-old
woman with dementia: a decision analysis. Am Geriatr Soc.
1995;155:171-175. Pubmed ID: 7884120
144. Zachariah B, Casey L, Balducci L. Radiotherapy of the
oldest old cancer patients: a study of effectiveness and
toxicity. J Am Geriatr Soc. 1995;43:793-795. Pubmed ID:
7602034
145. Zachariah B, Zachariah S, Varghese R, Balducci L. Review:
carcinomatous meningitis: clinical manifestations and
management. Int J Clin Pharmacol Ther Toxicol.
1995;33(1):7-12. Pubmed ID: 7711996
146. Balducci L, Barry P. A practical approach to the screening
of asymptomatic older persons with cancer. Cancer Control.
1994;1(2):126-131.
147. Balducci L, Cox C, Greenberg H, Lyman G, Miguel R, Karl
R, Fabri P. Management of cancer in the older aged person.
Cancer Control. 1994;1(2):132-137.
148. Balducci L, Greenberg H. Breast cancer in the older
woman: therapeutic controversies. Cancer Control.
1994;1(4):350-355.
149. Balducci L, Lyman G, Schapira D. Trends in prevention
and treatment of breast cancer in the older woman. Facts
Res Gerontol. 1994;179-192.
150. Balducci L, Lyman G. Cost-effectiveness of hematopoietic
growth factors in cancer management. Adv Oncol.
1994;10(1):11.
151. Balducci L. Cancer and age: issues and perspectives. Facts
Res Gerontol. 1994;173-178.
152. Balducci L. Do we need geriatric oncology? Cancer
Control. 1994;1(2):91-93.
153. Balducci L. Perspectives on quality of life of older persons
with cancer. Drugs Aging. 1994;4(4):313-324.
154. Beghe C, Balducci L, Cohen H. Secondary prevention of
breast cancer in the older woman: issues related to
screening. Cancer Control. 1994;1(4):320-326.
155. Lyman G, Balducci L. The effect of changing disease risk
on clinical reasoning. J Gen Intern Med. 1994;09:488-495.
156. Saba H, Nawab U, Nadeem S, Cosgrove D, Moscinski L,
Spiers A, Balducci L, Lyman G, Zuckerman K. 1994;624a.
157. Wyckoff J, Greenberg H, Sanderson R, Wallach P, Balducci
L. Breast irradiation in the older woman: a toxicity study. J
Am Geriatr Soc. 1994;42:150-152.
158. Balducci L, Benson K, Lyman G, Sanderson R, Fields K,
Ballester O, Elfenbein G. Cost-effectiveness of leukocyte
depletion filters in adult acute myelogenous leukemia.
Transfusion. 1993;33(8):665-670.
159. Ballester O, Moscinski L, Spiers A, Balducci L. NonHodgkin's lymphoma in the older person: a review. J Am
Geriatr Soc. 1993;41:1245-1254.
160. Iacobini M, Torre A, Palumbo G, DelPrincipe D, Digilio G,
Balducci L. Study of chronic granulomatous disease by a
nitroblue tetrazolium densitometric kinetic test: a new
research method. Clin Chim Acta. 1993;221:197-202.
161. Lyman G, Balducci L. Overestimation of test effects in
clinical judgment. J Cancer Educ. 1993;8(4):297-308.
162. Lyman G, Lyman C, Sanderson R, Balducci L. Decision
analysis of hematopoietic growth factor use in patients
receiving cancer chemotherapy. J Natl Cancer Inst.
1993;85(6):488-493.
163. Silliman R, Balducci L, Goodwin J, Holmes F, Leventhal E.
Breast cancer care in old age: what we know, don't know,
and do. J Natl Cancer Inst. 1993;85(3):190-199.
164. Virgilio J, Moscinski L, Ballester O, Corrado C, Guida C,
Balducci L, Saba H. Acute lymphoblastic leukemia (ALL) in
elderly patients. Hematol Oncol. 1993;11(3):121-126.
165. Balducci L, Mowrey K. Pharmacology and organ toxicity of
cancer chemotherapy in older patients. Oncology.
1992;6:62-68.
166. Ballester O, Moscinski L, Morris D, Balducci L. Acute
myelogenous leukemia in the elderly. J Am Geriatr Soc.
1992;40:277-284.
167. Ballester O, Wang T, Saba H, Morelli G, Tantranond O,
Balducci L. Classic hemophilia in elderly patients. J Am
Geriatr Soc. 1992;40(8):824-826.
168. Heal A, Tyson I, Greenberg H, Balducci L, Ketch R, Tenorio
L, Berman C, Silbiger M. Evaluation of multiple infusions (IP)
of 131-I-HMFG1 MoAb in ovarian and colorectal carcinoma
patients and a nude mouse xenograft with and without IV
use of unlabeled MoAb. Antibody Immunoconjugates
Radiopharm. 1992;5:86.
169. Saba H, Ballester O, Balducci L. Hemopoietic growth
factors in myelodysplasia. Hematol Rev. 1992;5:207-221.
170. Shank W, Balducci L. Hemopoietic growth factors and
aging: review. Hematol Rev. 1992;5:229-236.
171. Shank W, Balducci L. Recombinant hemopoietic growth
factors: comparative hemopoietic response in younger vs
older aged subjects. J Am Geriatr Soc. 1992;40:151-154.
172. Tantranond P, Karam F, Wang T, Parker M, Hescock H,
Cherryholmes D, Balducci L. Management of cutaneous
squamous cell carcinoma in an elderly man. Report of a
case and review of the literature. J Am Geriatr Soc.
1992;40:510-512.
173. Zachariah S, Zachariah B, Wang T, Balducci L. Primary
brain tumors in the older patient: an annotated review. J
Am Geriatr Soc. 1992;40:1265-1271.