Statistical Project for the Journal of the American Dietetic Association Revised 6/30/06 Team members: Sujata Archer Carol Boushey Barbara Bruemmer Jeff Harris Linda VanHorn Global Goals and Objectives: Goals: A. Assure the quality of statistical methods and documentation in the Journal research articles B. Support statistical competence and capability for members of ADA including authors, readers and students. Objective: 1. Provide member value as a statistical resource C. Develop a framework to deliver content on statistical methods using workshops, print and web-based information. Objectives: 1. Prioritize statistical methods for inclusion in the content. (Process objective) 2. Include methods that have application in a range of practice areas and baseline skills. 3. Promote the use of evidence based medicine and evidence based practice. 4. Develop statistical case studies that include: a. Research scenario b. Components for presentation c. Model statement of statistical results d. Resources and references D) Assess unmet needs and revise deliverables on an ongoing basis Project Mechanism Title / Content Proposed date Manuscripts Print Content: Article2 Submit:_____ Statistical procedures (common procedures; some common mistakes, such as clarification between different correlation coefficients, using independent tests with dependent samples) Lead: CB/ JH Describing Statistical Results: Non-parametric/ parametric Manuscripts Manuscripts Print Print Content: (See outline attached) Publishing Nutrition Research: A Review of Nonparametric Methods, Part 3 Article 3 Objectives The reader will understand the rationale for using nonparametric methods. The reader will know the difference between parametric and nonparametric statistical methods. The reader will list the nonparametric alternative to parametric methods. The reader will apply the correct nonparametric test to the appropriate variable situation. Lead: JH Content: (See outline attached) Article 4 Statistical procedures (common procedures; some common mistakes, such as clarification between different correlation coefficients, using independent tests with dependent samples Target Date Epidemiology Lead: BB ORs; RRs; CIs; Statistical Significance; Chance; Confounding; Interaction; Target Date Summer 2006 Manuscripts Print Content Article 5 Target Date: Use of appropriate measurement and diagnostic tools (validity testing, sensitivity, specificity, validity, reliability, relative validity). Measurement issues with surveys include: validity, content validity, construct validity, internal consistency, and test-retest reliability. Summer 2006 Lead: SA Making appropriate inferences based on the study design, sampling and results (a-priori hypothesis testing, post-hoc analyzes, extrapolation) 'Research Successful Approaches' Text Contribute Chapters as outlined (see attached) June 2006 Guidelines for Authors Web Page Purpose: Provide additional resources on research design and methods. Include links to statistical resources for analysis. Target date mid-winter FNCE Workshop Resubmit for FNCE 2007 2007 Interactive Learning “Sex, Drugs, and Diet…in Table 1: Research Design and Biostatistics” Integrate with stats project goals, e.g. manuscripts and presentations. August 16, 2006 Lead: Jeff Harris, DrPH, MPH, RD, LDN; West Chester University of PA Participants will interpret nutrition research designs and apply appropriate statistical solutions to their own research projects. Further discussion of the quality control measures needed to strengthen accuracy and validity of outcomes will be emphasized. The intention is to empower the dietitian to be an active initiator and contributor to the research process that results in manuscripts that merit publication in the Journal of the American Dietetic Association. Carol J. Boushey PhD, MPH, RD; Purdue Discuss the variety of nutrition-related research designs. Clarify the types of conclusions that can be drawn from each type of design. List the common errors researchers make when designing research projects and reporting on the results. George P. McCabe PhD; Purdue Discuss how biostatistical methods can be applied to different types of data derived from nutrition-related research designs. Comment on mistakes researchers make in the application and interpretation of biostatistical methods. Discuss how researchers can best collaborate with a biostatistician to assist with conducting and reporting research. Completed Projects: Guidelines for Authors Print Statistics Project 2005 Author Guidelines (Refer to meeting materials) Completed Manuscripts Print ‘Nutrition Research: Publishing Secrets from the Statistical Pros’ Published Carol J. Boushey, Jeff Harris, Barb Bruemmer, Sujata Archer, Linda Van Horn Content: Study Design (types, descriptions) Study hypothesis, purpose, or objective Publishing Nutrition Research: A Review of Nonparametric Methods, Part 3- Jeff Objectives 1. The reader will understand the rationale for using nonparametric methods. 2. The reader will know the difference between parametric and nonparametric statistical methods. 3. The reader will list the nonparametric alternative to parametric methods. 4. The reader will apply the correct nonparametric test to the appropriate variable situation. I. Introduction. A. Third installment of a series of papers on data analysis and statistical methods. B. Will cover univariate and bivariate nonparametric statistical tests. C. Contrasts nonparametric and parametric methods. D. Instructs on how to pick appropriate nonparametric test in different univariate and bivariate situations. II. Rationale for Nonparametric Methods. A. Reasons for use of nonparametric tests. III. Advantages and Disadvantages of Nonparametric Methods. IV. Nonparametric Alternatives to Parametric Tests. V. Measures of Central Tendency for Nonparametric Situations. A. The median. VI. Wilcoxon Rank-Sum Test/Mann-Whitney Test. VII. Wilcoxon Signed-Rank Test. VIII. Kruskal-Wallis One-Way ANOVA by Ranks/Median Test. IX. The One-Sample Sign Test. X. Spearman Rank-Order Correlation Coefficient. XII. Kolmogorov-Smirnov test XIII. Friedman’s Test. XIV. McNemar (the cousin to the paired t-test). XV. The Chi-Square Test. XVI. Conclusions. Note: Will attempt to use examples from JADA. Outline: Manuscript 4 – Barb Introduction: Acknowledge our series of articles to orient the reader Wide use of epidemiological study designs in the nutrition field Purpose Review of epi methods for potential investigators and scientific writers Review for readers of evidence based research A. Examples of study questions (possibly 2 – one diet, one disease) that use epi methods – Purpose of this section is to orient the reader and provide two –three scenarios that will be used throughout the manuscript B. The role of observational studies in advancing knowledge Quality of studies as ranked in the Cochrane Collaborative – ‘Levels of Evidence’ Definitions – related to glossary as we have been doing Causal hypotheses – limitations in epi studies C. Basic framework of an epi study – terms and examples Exposure Outcome Confounders Bias Misclassification D. Designs Purpose Statement of the hypothesis Strengths and weaknesses 1. Cross sectional 2. Case-Control 3. Cohort E. Statistical tests Common tests - χ2, logistic regression, survival analysis, Kaplan Meier Odds Ratio, RR; CI, interpretation that findings are not due to chance (significance) Appropriate presentation of results F. Interpretation, limitations, resources Research: Successful Approaches, third edition TOC Updated: 5/15/2006 Contributors, Foreword, Introduction Part 1: An Introduction to Discovery Through Research in Nutrition and Dietetics Ch 1: Steering Through the Research Continuum Elaine R. Monsen, PhD, RD and Linda Van Horn, PhD, RD Ch 2: Building the Research Foundation: The Research Question and Study Design Carol Boushey, PhD, MPH, RD, Jeffrey Harris, Dr.PH, RD, Bruemmer, PhD, RD, and Sujata Archer, PhD, RD Barbara Part 2: Establishing and Maintaining a Research Environment Ch 3: Conducting and Presenting Research Ethically Elaine R. Monsen, PhD, RD Ch 4: How to Write Proposals and Obtain Funding Dianne Neumark- Sztainer, PhD, MPH, RD Ch 5: Multi-disciplinary research Madeleine Sigman-Grant, PhD, RD Part 3: Descriptive Research Ch 6: Descriptive Epidemiologic Research Sujata Archer, PhD, RD Ch 7: The Philosophy, Role, and Methods of Qualitative Inquiry in Research Cheryl L. Achterberg, PhD, Susan Wohlsdorf-Arendt, PhD, RD, Sandi Shepherd, PhD. Part 4: The Conduct of Observational and Experimental Research Studies Ch 8: Analytic Nutrition Epidemiology Monica E. Yamamoto, Dr.PH, RD, FADA Ch 9: Designing, Managing, and Conducting a Clinical Nutrition Study P.M. Kris-Etherton, PhD, RD Ch 10: Interpretation and Utilization of Data from the National Nutrition Monitoring and Related Research Program Ronette R. Briefel, Dr.PH, RD Part 5: Integrative and Translational Research Ch 11: Meta-analysis in Nutrition Research Judith Beto, PhD, RD Ch 12: Research in Evidence-based Practice Esther F. Myers, PhD, RD Part 6: Evaluation and Assessment Methods in Research Ch 13: Design and Use of Questionnaires in Research Barbara E. Millen, PhD, RD Ch 14: Dietary Assessment and Validation Rachel K. Johnson, PhD, MPH, RD, Bethany A. Yon, MS, Jean Hankin, Dr.PH, RD Ch 15: Food Composition Data and Databases Jean A.T. Pennington, PhD, RD Ch 16: DRIs, ERAs, ULs, etc Suzanne Murphy, PhD, RD Ch 17: Biomarkers in Nutrition Research Cheryl L Rock, PhD, RD, FADA, and Johanna W Lampe,PhD, RD Ch 18: Culture and Research Yvonne Bronner PhD, RD Ch 19: Research Methods for Human Sensory System Analysis and Food Evaluation Richard D Mattes, PhD, RD and Beverly Cowart, PhD Ch 20: Research Methods in Appetite Assessment Richard D Mattes, PhD, RD Part 7: Key Aspects of Research in Food, Nutrition, and Dietetics Ch 21: Outcomes Research and Economic Analysis Patricia L. Splett, PhD, RD, FADA Ch 22: Research in Diet and Human Genetics Cheryl L. Rock, PhD, RD, FADA Ch 23: Behavioral Theory-based Research Geoffrey W. Greene, PhD, RD Ch 24: Research Methods for Dietary Supplements and Complementary and Alternative Medicine Cynthia Thomson PhD, RD and Leila Saldanha PhD, RD Ch 25: Research in Foodservice Management Bonnie L. Gerald, Ph.D DTR, Mary Cluskey, PhD, RD Ch 26: Research Techniques Used to Support Marketing Management Decisions Kathleen Reidy, PhD, RD Ch 27: Dietetics Education Research Mary B. Gregoire, PhD, RD, FADA Part 8: Application of Statistical Analysis in Nutrition and Dietetics Research Ch 28: Estimating Sample Size Carol Boushey, PhD, MPH, RD, Jeffrey Harris, Dr.PH, RD, Barbara Bruemmer, PhD, RD, and Sujata Archer, PhD, RD Ch 29: Fundamentals of Statistical Analysis Carol Boushey, PhD, MPH, RD, Jeffrey Harris, Dr.PH, RD, Barbara Bruemmer, PhD, RD, and Sujata Archer, PhD, RD Part 9: Presentation of Research Data Ch 30: Techniques and Approaches for Presenting Research Findings Judith A Driskell, PhD, RD, Elaine Monsen PhD, RD Ch 31: Illustrating the Results of Research Shortie McKinney, PhD, RD Ch 32: Research Publications: The Perspectives of the Writer, Reviewer, and Reader Jeffrey Harris, Dr.PH, RD CODA Applications of Research Practice Ch 33: Bridging Research to Practice Judith A. Gilbride, PhD, RD Statistical concepts to emphasize and integrate throughout the book: Research Hypotheses and Questions Directional and Nondirectional Hypotheses (one-tailed and two-tailed tests) Types of Variables Scales of Measurement Measures of Central Tendency Measures of Dispersion Types of Distributions and Central Limit Theorem Skewness and Kurtosis Descriptive Statistics Research Designs (observational vs experimental) Designs, and Cause and Effect Inferential Statistics Decision-Making Hypothesis Testing (steps) Confidence Intervals Z-scores t-tests ANOVA Pearson’s Correlation Regression Nonparametric Tests Odds Ratio Relative Risk RatioIntent to Treat Numbers Needed to Treat Diagnostic Testing Specificity and Sensitivity Predictive Values Likelihood Ratios Advanced Statistical Tests Multiple Regression Logistic Regression Cluster Analysis Factor Analysis Canonical Correlation Discriminant Analysis Log-Linear Modeling Path Analysis Interpretation of Statistical Tests Computer Statistical Packages