Curriculum Vitae Name: Chih-Shung Wong, MD, PhD Date of Birth: 1956/08/25 Place of Birth: Taipei, Taiwan Education: MD, National Defense Medical Center, Taipei, Taiwan (1974-1981) PhD, Duke University, Durham, North Carolina, USA (1988-1992) Internships and residencies: Internship: Veteran General Hospital, Taipei (1979-1981) Resident: Tri-Service General Hospital, Taipei (1981-1986) Licensure and Certification: Board certification: Anesthesiology, Critical Care Medicine, Pain Management, Professional and Occupational Medicine and Cardiovascular Anesthesia Academic Appointments: Chairman, School of Medicine, National Defense Medical Center Deputy Superintendent, Education and Research Affairs Tri-Service General Hospital Professor, Department of Anesthesiology, National Defense Medical Center Other Appointments: Chairman, Institutional Review Board, Tri-Service General Hospital (2000- now) Director, Department of Education and Research, Tri-Service General Hospital Director, General Clinical Research Center, Tri-Service General Hospital Acting Director, Department of Research and Development, National Defense Medical Center (Feb. 1 to Mar. 16, 2009) Executive Associate Editor-in-Chief, Acta Anaesthesiologica Taiwanica Standing Committee Board Member, Anesthesiologists of Taiwan Society of Anesthesiologists Chairman, Board Examination Committee, Anesthesiologists of Taiwan Society of Anesthesiologists Chairman, Continued Education Committee, Anesthesiologists of Taiwan Society of Anesthesiologists Standing Committee Board Member, Taiwan Association of Study of Pain Chairman, Pain Management and Education of Anesthesiologists of Taiwan Society of Anesthesiologists Chairman, Board Examination Committee, Taiwan Association of Study of Pain (2006-2009) Major Research Interests: 1. Mechanisms of opioid tolerance 2. Mechanisms and management of neuropathic pain 3. Interactions among opioid, NMDA, and other pain facilitatory receptor systems (NO-COX) 4. Clinical postoperative, cancer and neuropathic pain management 5. Mechanisms of spinal cord ischemic injury and preconditioning 6. Immunonociception signal transduction 7. Cellular mechanisms of early osteoarthritis Reviewer of Journals: 1. Acta Anesthesiological Taiwanica 2. 3. 4. Academy of Sciences and Arts of Bosnia and Herzegovina Anesthesia and Analgesia Anesthesiology 5. 6. 7. 8. 9. 10. 11. Brain Research British Journal Anaesthesia Chinese Journal of Pain Clinical Anesthesia Informa Healthcare International Journal of Neuropsychoparmacology Journal of Formosa Medical Association 12. 13. 14. 15. 16. 17. 18. Journal of Medical Sciences Journal of Neurochemistry Journal of Pharmacy and Pharmacology Neuroscience Letter Pharmacology, Biochemistry and Behavior Sacoor Medical Group Taiwan Critical Care Medicine Publications: 01.Wong CS, Chou YP, Chang CL. Surface landmarks of parascalene brachial plexus block. Acta Anestheisol Sin 21:87-92, 1983. 02.Wong CS, Ho ST, Hou CC, Peng TY, Hsu CS, Ho Weber, Chang CL. Effects of physostigmine on the loss of consciousness induced by i.v. thiopentone and ketamine in man. Acta anesthesiol Sin 23:49-53, 1985. 03.Hsu JC, Hou CC, Wong CS, Wei J, Chang CL. Profound hypothermia with total circulatory arrest in cardiac anesthesia. Acta Anesthesiol Sin 23:144-148, 1985. 04.Hsu JC, Wong CS, Chen TS, Chang CL. Comparsions of the cardiovascular and antisialogogue effects among glycopyrrolate, scopolamine and atropine in man. Acta Anesthsiol Sin 24:39-44, 1986. 05.Hou CC Chou YP, Hwang CJ, Wong CS, Chang CL. The changes of arterial oxygen saturation during transfer to the recovery room. Acta Anesthesiol Sin 24:212-215, 1986. 06.Wong CS, Ho ST, Hu OYP, Pen TY, Ho Weber, Chang CL. Induction doses of etomidate, althesin and midazolam in Chinese.Acta Anesthesiol Sin 24:243-250, 1986. 07.Nishino K, Su YF, Wong CS, Watkins WD and Chang KJ. Dissociation of mu opioid tolerance from receptor down-regulation in rat spinal cord. J Pharmacol Exp Ther 253: 67-72, 1990. 08.Ho ST, Wong CS, Hu OYP, Wang Y, Yen MH and Ho W. Effect of physostigmine on the loss of consciousness induced by midazolam, etomidate and althesin. Acta Anesthesiol Sin 29: 643-647, 1991. 09.Wong CS, Su YF, Chang KJ and Watkins WD. Intrathecal pertussis toxin treatment attenuates opioid analgeisa and reduces high-affinity state of opioid receptors. Anesthesiology 77: 691-699, 1992. 10.Wong CS, Su YF, Watkins WD and Chang KJ. Continuous intrathecal opioid treatment abolishes the regulatory effects of magnesium and guanine nucleotides on -opiod receptor binding in rat spinal membranes. J Pharmacol Exp Ther 262: 317-326, 1992. 11.Tsaur GR, Liaw WJ, Wong CS, Yu FK and Ho ST. Treacher-Collin's syndrome and translaryngeal guided intubation: a case report. Acta Anesthisol Sin 32: 223-227, 1994. 12.Lu YH, Liaw WJ, Chang WT, Wong CS and Ho ST. Stroke-like complication after abdominal surgery: a case report of chronic subdural hematoma. Chin Med J 54: 141-144, 1994. 13.Wong CS*. Opioid receptors and their mechainsms of action. Chinese J Pain 4: 71-94, 1994. 14.Wong CS*. The mechainsms of opioid tolerance in rat spinal cord. Med Digest 18: 205-212, 1994. 15.Wong CS, Su YF, Watkins WD, Chang KJ. Opioid agonist binding affinity is increased by magnesium in the presence of guanosine diphosphate but decreased by magnesium in the presence of guanly-5'-yl imidodiphosphate. J Pharmacol Exp Ther 268: 653-661, 1994. 16.Wong CS*. The mechainsms of opioid tolerance and desensitization. Chinese J Pain 4: 43-53, 1994. 17.Liaw WJ, Wong CS, Wang JJ, Tsaur GR, Lee SH, Ho ST. The effects of co-administration epidural lidocaine with different analgesics on tourniquet-induced pain. Chinese J Pain 5:39-46, 1995. 18.Ho ST, Wang JJ, Liaw WJ, Wong CS, Cherng CH. Analgesic effect of intra-articular morphine after arthroscopic knee surgery in Chinese patients. Acta Anesthesiol Sin 33: 79-84, 1995. 19.Lu CC, Chang YT, Hwang CC, Liaw WJ, Shieh JP, Wong CS, Ho ST. Fat embolism syndrome following bilateral total knee replacement with total condylar prosthesis: a case report. Act Anesthesiol Sin 33: 69-71, 1995. 20.Wong CS*, Cherng CH, Ho ST. Clinical applications of excitatory amino acid antagonists in pain management. Acta Anesthesiol Sin 33: 227-232, 1995. 21.Chu YH, Wong CS*, Ho ST, Watkins WD. Epidural coadminstration of ketamine and morphine attenuates neurogenic pain: a case report. The Pain Clinic 8: 263-267, 1995. 22.Cherng CH, Wong CS, Ho ST. Spinal actions of non-steroidal anti-inflammatory drugs. Acta Anesthesiol Sin 34: 81-87, 1996. 23.Wong CS*, Shen TT, Liaw WJ, Cherng CH, Ho ST. Epidural co-administration of ketamine, morphine and bupivacaine atteunates post-herpetic neuralgia: a case report. Acta Anesthesiol Sin 34: 151-155, 1996. 24.Tao PL, Wong CS, Lin MJ. Chronic intrathecal morphine treatment dose not cause down-regulation of spinal adenosine A1 receptors in rats. Naunyn-Schmiedeberg's Arch Pharmacol 354: 187-191, 1996. 25.Yang CY, Wong CS, Yu CC, Luk HN, Lin CI. Propofol inhibits cardiac L-type calcium current in guinea-pig ventricular myocytes. Anesthesiology 84: 626-635, 1996. (SCI)(83-0412-B-016-86) 26.Yang CY, Wong CS, Chang JY, Ho ST. Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain. Can J Anesth 43: 379-383, 1996. (SCI) (83-0412-B-016-075) 27.Wong CS*, Cherng CH, Luk HN, Ho ST, Tung CS. Effect of NMDA receptor antagonists on inhibition of morphine tolerance in rats: binding of -opioid receptors. Eur J Pharmacol 297: 27-33, 1996. 28.Chen FC, Cherng CH, Hwang SJ, Wong CS, Ho ST. Removal of femoral interlocking nail-induced pulmonary embolism under spinal anesthesia: a case report. Acta Anesthesiol Sin 34: 247-251, 1996. 29.Liaw WJ, Ho ST, Wang JJ, Wong CS, Lee HK. Cellular mechanism of opioid tolerance. Acta Anesthesiol Sin 34: 221-234, 1996. 30.Wong CS*, Liaw WJ, Tung CS, Ho ST. Ketamine potentiates morphine analgesic effect in postoperative epidural pain control. Reg Anesth 21: 534-541, 1996. (SCI) (83-0412-B-016-022) 31.Huang NK, Tseng CJ, Wong CS, Tung CS. Effects of acute and chronic morphine on DOPAC and glutamate at subcortical DA terminal in awake rats. Pharmacol Biochem Behavior 56: 363-371, 1997. 32.Wong CS*, Lu CC, Cherng CH, Ho ST. Pre-emptive analgesia with ketamine, morphine and epidural lidocaine prior to total knee replacement. Can J Anaesth 44: 31-37, 1997. (SCI) (84-2331-B-016-087) 33.Lin TC, Wong CS*, Chen FC, Lin SY, Ho ST. Long-term epidural ketamine, morphine and bupivacaine attenuate reflex sympathetic dystrophy neuralgia. Can J Anaesth 45: 175-177, 1997. 34.Li CY, Chou TZ, Wong CS, Wu CC, Ho ST, Yen MH, Ding YA. Ketamine inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophpages. Can J Anaesth 44: 989-995, 1997. (SCI) 35.Liu ST, Huang SJ, Wong CS, Wu CT, Ho ST. Brachial plexus injury surgery -- Report of two cases. Act Anaesth Sin 35: 181-185, 1997. 36.Wu CT, Li CY, Wong CS, Ho ST, Chu CC, Diao GY, Chang YT. The lost endotracheal tube -- A rare complication of accidental esophageal intubation. Act Anaesth Sin 35: 55-58, 1997. (ISSN) 37.Li CY, Chou TZ, Wu CC, Wong CS, Ho ST, Ding YA. Dantrolene inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophages. Can J Anaesth 45: 246-252, 1998. (SCI) 38.Li CY, Wu CT, Wong CS, Ho ST. Halothane requirement - a comparison between laryngeal mask airway insertion and endotracheal tube intubation in paediatric patients. Act Anaesth Sin 36: 37-41, 1998. (ISSN) 39.Wu CT, Ho ST, Tsai CS, Wang JJ, Wong CS, Li CY, Liu ST. Repeated lumbar blockade for complex regional pain syndromes type I - a case report. Act Anesthesiol Sin 36:155-158, 1998. (ISSN) 40.Yeh CC, Ho ST, Wong CS, Liaw WT, Wang JJ, Tang JJS. Manipulation of epidural catheter that has migrated restores adequate postoperative analgesia - a case report. Act Aneshtesiol Sin 36:59-62, 1998. (ISSN) 41.Chia YY, Liu C, Lin YC, Chang HC, Wong CS. Adding ketamine in a multimodal patient controlled epidural regimen reduces postoperative pain and analgesics consumption. Anesth Analg 86:1245-1249, 1998. (SCI) 42.Wong CS*, Cherng CH, Tung CS. Intrathecal administration of excitatory amino acid antagonists or nitric oxide synthase inhibitor reduced autotomy behavior in the rat. Anesth Analg 87:605-608, 1998. (SCI) (DOH 85-HR-402 and NSC 85-2331-B-016-010) 43.Lin SY, Wu CT, Yeh CC, Liu ST, Ho ST, Wong CS*. Ephedrine-induced complete atrioventricular block with ventricular asystole during rapid concomitant phenytoin infusion: a case report. Act Anesthesiol Sin 37:45-48, 1999. (ISSN) 44.Yeh CC, Yu JC, Wu CT, Ho ST, Chang TM, Wong CS*. Thoracic epidural anesthesia provides a better pain relief and postoperative recovery for modified radical mastectomy. World J Surg 23:256-261, 1999. (SCI) (DOH-86-HR-402 and NSC-86-2314-B-016-071) 45.Wu CT, Yu JC, Yeh CC, Liu ST, Li CY, Ho ST, Wong CS*. Precisional dextromethorphan treatment decreases postoperative pain and opioid requirement after laparoscopic cholescystectomy. Anesth Analg 88:1331-1334, 1999 (SCI) (NSC 86-2314-B-016-071 and DOH 87-HR-402).. 46.Chang FL, Wu CT, Yeh CC, Lin TC, Ho ST, Wong CS*. Postoperative intramuscular dextromethorphan injection provides postoperative pain relief and decreases opioid requirement after hemorrhoidectomy. Acta Anaesthesiol Sin 37:179-183, 1999. 47.Wong CS*, Wu CT, Yu JC, Yeh CC, Lee MMS, Tao PL. Preincisional dextromethorphan decreases postoperative pain and opioid requirement after modified radical mastectomy. Can J Anaesth 46:1122-1126, 1999. (SCI, TSGH-C89-40 and NHRI-GT-EX89B909P). 48.Lin HC Wan FJ, Kang BH, Wong CS, Mao SP. Systemic administration of D-amphetamine induced a delayed production of nitric oxide in the striatum of rats. Neurosci Lett 276:141-144, 1999. (SCI, DOH 88-TD-1116 and NSC 88-2314-B-016-106-082) 49.Kong SS, Yeh CC, Ho ST, Wu CT, Tsou YW, Wong CS*. Obstruction of an armoured endotracheal tube: report of two cases. J Med Sci 20:29-33, 1999. 50.Wan FL, Lin HC, Huang KL, Tseng CJ, Wong CS. Systemic administration of D-amphetamine induces long-lasting oxidative stress in the rat striatum. Life Sci 66: PL205-212, 2000. (DOH 89-TD-1126). 51.Wu CT, Yeh CC, Yu JC, Lee MMS, Tao PL, Ho ST, Wong CS*. Pre-incisional epidural ketamine, morphine and bupivacaine combined with epidural and general anesthesia provides pre-emptive analgesia for upper abdominal surgery. Acta Anaesthesiol Scand 44:63-68, 2000. (TSGH-C88-049 and HOD-87-HR-402) 52.Wu CT, Yu JC, Liu ST, Yeh CC, Li CY, Wong CS*. Preincisional dextromethorphan treatment provides a better postoperative pain management in upper abdominal surgeries. World J Surg 24:63-68, 2000. (SCI) 53.Liu ST, Wu CT, Yeh CC, Ho ST, Jao SW, Wu CC, Kang JC, Wong CS*. Premedication with dextromethorphan provides post-hemorrhoidectomy pain relief. Dis Colon Rectum 43:507-510, 2000. (SCI, TSGH-C89-057 and DOH-88-HR-402). 54.Hsu JH, Ho ST, Lin TC, Yeh, CC, Wong CS*. Convulsion during superior laryngeal nerve block: a case report. Act Anesthsiol Sin 38:93-96, 2000. 55.Wu CT, Yu JC, Yeh CC, Lee MMS, Lin TC, Wong CS*. Postoperative intramuscular dextromethorphan injection provides pain relief and decreases opioid requirement after modified radical mastectomy. Int J Surg Invest 2:145-149, 2000. (NHRI-GT-EX89B909P) 56.Wong CS*, Hsu MM, Chou YY, Tao PL, Tung CS. Morphine tolerance increases [3H]MK-801 binding affinity and constitutive neuronal nitric oxide synthase expression in rat spinal cord. Br J Anaesth 85:587-591, 2000. (SCI, DOH-86-HR-402 and NSC 86-2314-B-016-071). 57.Wong CS*, Hsu MM, Chou YY, Tung CS. Intrathecal cyclooxygenase inhibitor administration attenuates morphine antinociceptive tolerance in rats. Br J Anaesth 85:747-751, 2000. (SCI, DOH-86-HR-402 and NSC 86-2314-B-016-071). 58.Ho YJ, Chang YC, Liu TM, Tai MY, Wong CS*, Tsai YF. Straital glutamate release during novelty exposure-induced hyperactivity in olfactory bulbectomized rats. Neurosci Lett 287:117-120, 2000. (SCI) 59.Huang GS, Kong SS, Ho ST, Wong CS*. Intra-articular ketamine for pain control following arthroscopic knee surgery. Act Anesthesiol Sin 85:131-136, 2000. 60.Hsu MM, Wong CS*. The roles of pain facilitatory systems in opioid tolerance. Act Anesthesiol Sin 38:155-155, 2000. 61.Wu CT, Wong CS*. Pain control in intensive care unit. Taiwan Crit Care Med 2:288-299, 2000. 62.Kong SS, Ho ST, Cherng CH, Wong CS*. Rhabdomyolysis after a long-term thoracic surgery in right decubitus position. Act Anesthesiol Sin 38:223-228, 2000. 63.Yeh CC, Ho ST, Kong SS, Wu CT, Wong CS*. Preemptive analgesic effect of dextromethorphan in total knee replacement. Act Anesthesiol Sin 38:187-193, 2000. 64.Cherng CH, Wong CS, Ho ST. Acute aphesia following tournique release in intravenous regional anesthesia with 0.75% lidocaine (letter). Reg Anesth Pain Med 25:211-212, 2000. 65.Wong CS*. What’s the matter of depth of anesthesia? Act Anesthesiol Sin (editorial view) 39:1-2, 2001. 66.Wang JJ, Ho ST, Wong CS, Tzeng JI, Liu HS, Ger LP. Dexamethasone prophylaxis of nausea and vomiting after epidural morphine for post-cesarean analgesia. Can J Anaesth 48:185-190, 2001. 67.Yang CP, Kong SS, Ho ST, Cherng CH, Wong CS*. Overinflated cuff causes tracheal stenosis in inhalation injury patient: a case report. J Med Sci 21:49-52, 2001. 68.Ho YJ, Liu TM, Tai MY, Wen ZH, Chow RS, Tasi YF, Wong CS*. Effect of olfactory bulbectomy on the NMDA receptors density in the rat brain: [3H]MK-801 binding assay. Brain Res 900:214-218, 2001. 69.Cherng CH, Wong CS, Ho ST. Facilitation of fiberoptic nasotracheal intubation by simultaneous direct laryngoscopy in anesthetized patients. Acta Anaesthesiol Sin 39:103-106, 2001. 70.Wen ZH, Wong CS, Lin CR, Chou AK, Tan PH, Chang YC, Kao CH, Cheng TJ, Yang LC. Changes in the levels of nitric oxide synthase and protein kinase C gamma following kainic acid receptor activation in the rat spinal cord. Neurosci Lett 309:25-28, 2001. 71.Hsu MM, Chou YY, Chang YC, Chou TC, Wong CS*. An analysis of excitatory amino acids, nitric oxide, and prostaglandin E2 in the cerebrospinal fluid of pregnant women: the effect on labor pain. Anesth Analg 93:1293-1296, 2001. 72.Cherng CH, Wong CS, Ho ST. Epidural fentanyl speeds the onset of sensory block during epidural lidocaine anesthesia. Reg Anesth Pain Med 26:523-526, 2001. 73.Ho LJ, Chang DM, Shiau HY, Chen CH, Hsieh TY, Hsu YL, Wong CS, Lai JH. Aspirin differentially regulates endotoxin-induced IL-12 and TNF- production in human dendritic cell. Scand J Rheumatol 30:346-352, 2001. 74.Wong CS, Ho ST, Cherng CH. The prevalence of phantom breast syndrome after mastectomy is low in Chinese patients (letter). The Breast 10:549-500, 2001. 75.Cherng CH, Wong CS, Ho ST. The prevalence and clinical characteristics of phantom rectum syndrome after rectum resection in Chinese patients. The Pain Clinic 13:113-117, 2001. 76.Lin TC, Hsu CH, Kong SS, Cherng CH, Wong CS*. Ventricular asystole and complete heart block after thoracic epidural analgesia for thymectomy. Eur J Anaesth 19:460-462, 2002. 77.Lu CH, Ho ST, Kong SS, Cherng CH, Wong CS*. Intracranial subdural hematoma after unintended durotomy during spine surgery. Can J Anaesth 49:100-102, 2002. 78.Yang CP, Cherng CH, Wong CS, Ho, ST. Effect of intravenous ketorolac and fentanyl combined with midazolam on analgesia and side effects during extracorporeal shock wave lithrotripsy. Acta Anaesth Sin 40:9-12, 2002. 79.Cherng CH, Wong CS, Chang FL, Ho ST, Lee CH. Epidural morphine delays the onset of tourniquet pain during epidural lidocaine anesthesia. Anesth Analg 94:1614-1616, 2002. 80.Cherng CH, Wong CS, Ho ST. Ropivacaine-induced convulsions immediately after epidural adminstration – a case report. Acta Anaesth Sin 40:43-45, 2002. 81.Cherng CH, Wong CS, Hsu CH, Ho ST. Airway length in adults: estimation of the optimal endotracheal tube length for orotracheal intubation. J Clin Anesth 14:271-274, 2002. 82.CS Wong*, Chang YC, Yeh CC, Huang GS, Cherng CH. Loss of intrathecal morphine analgesia in terminal cancer patients is associated with high levels of excitatory amino acids in the CSF. Can J Anaesth 49:561-565, 2002. 83.Hunag WS, Chou TD, Chen TM, Wang HJ, Lee GY, Wong CS. Nasal ala pressure sores: easily missed complications of nasotracheal tube intubation. J Med Sci 22:101-104, 2002. 84.Pang WW, Mok MS, Wong CS, Yen M, Chang DP. Can neostigmine reduce propofol injection pain? Acta Anaesthesiol Sin 40:65-69, 2002. 85.Huang GS, Wang HJ, Chen CH, Ho ST, Wong CS*. Rupture of pulmonary artery by a sutured continuous cardiac output pulmonary artery catheter after open-heart surgery. Anesth Analg 95:200-301, 2002. 86.Chan SL, Chou CC, Wong CS, Wu CC, Tao PL. Study the effect and mechanism of dextromethorphan on preventing the development of morphine tolerance and dependence in rats. J Med Sci 22:171-176, 2002. 87.CS Wong*. Long-term opioid treatment: the role of pain facilitatory system. Acta Anaesthesiol Sin 40:105-107, 2002. 88.Huang GS, Chang JH, Lee MS, Wu CC, Lin SP, Lin SL, Wong CS*. The effect of anaesthetic techniques on haemostatic function in arthroscopic surgery: an evaluation by thromboelastography. Acta Anesth Sin 40: 121-126, 2002. 89.Chen SL, Wong CS, Ho ST, Chang FL, Hsu CH, Wu CT. A Lethal Pulmonary Embolisn During Percutaneous Vertebroplasty. Anesth Analg 95:1060-1062, 2002. 90.Yeh CC, Wu CT, Wong CS*. The use of vasopressin in critical ill patients. Taiwan Crit Care Med 4:251-260, 2002. 91.Chang FL, Huang GS, Cherng CH, Ho ST, Wong CS*. Multiple peripheral nerve blocks by coadministration of ketamine, morphine, and bupivacaine attenuates trigeminal neuralgia – correspondence. Can J Anesth 50:201-202, 2003. 92.Lui YC, Wu RSC, Wong CS. Unexpected complication of attempted epidural anesthesia: Cauda equina syndrome. Anaesth Intensive Care 31:461-464, 2003. 93.Wen ZH, Guo YW, Chang YC, Wong CS*. D-2-amino-5-phosphonopentanoic acid inhibits intrathecal pertussis toxin-induced thermal hyperalgesia and protein kinase C up-regulation. Brain Res 963:1-7, 2003. 94.Wen ZH, Yang LC, Chen JY, Hsing CH, Chang YC, Wang JJ, Wong CS*. Intrathecal pertussis toxin induces thermal hyperalgesia: involvement of excitatory and inhibitory amino acids. Neuroscience 116:871-878, 2003. 95.Wang FL, Lee LC, Lee SH, SL Wu, Wong CS*. Performance evaluation of quality improvement team in an anesthesiology department. Acta Anesthesiol Sin 41:13-19, 2003. 96.Yeh CC, Kong SS, Chang FL, Huang GS, Ho ST, Wu CT, Wong CS*. Closed-circuit anesthesia prolongs the neuromuscular blockade of rocuronium. Act Anaesthesiol Sin 41:55-60, 2003. 97.Wang HJ, Wong CS, Chiang CY, Yeh CC, Cherng CH, Ho ST, Wu CT. Low-dose vasopressin infusion can be an alternative in treating patients with refractory septic shock combined with chronic pulmonary hypertension – a case report. Act Anaesthesiol Sin 41:77-80, 2003. 98.Ger LP, Lee MC, Wong CS, Chao SS, Wang JJ, Ho ST. The effect of education and clinical practice on knowledge enlightenment and attitudes toward the use of analgesics for cancer pain among physicians and medical student. Act Anaesthesiol Sin 41:105-114, 2003. 99.Li CY, Chou TC, Lee CH, Tsai CS, Loh SH, Wong CS. Adrenaline inhibits liopoplysaccharide-induced macrophage inflammatory protein-1 in human monocytes: the role of -adrenergic receptors. Anesth Analg 96:518-523, 2003. 100. Li CY, Tsai CS, Cheuh SH, Hsu PC, Wang CY, Wong CS, Ho ST. Dobutamine inhibits monocyte chemoattractant protein-1 production and chemotaxis in human monocytes. Anesth Analg 97:205-209, 2003. 101. Li CY, Tsai CS, Hsu PC, Wu CT, Wong CS, Ho ST. Dobutamine modulates lopopolysaccharide-induced macrophage inflammatory protein-1 alpha and interleukin-8 production in human monocytes. Anesth Analg 97:210-215, 2003. 102. Chen HL, Wu CT, Wong CS*. Fat and bone marrow embolism during percutaneous vertebroplasty: In response. Anesth Analg 97: 294, 2003. 103. Lu CC, Tsai CS, Ho ST, Chen WY, Wong CS, Wang JJ, Hu OYP, Lin CY. Pharmacokinetic of sevoflurane uptake into the brain and body. Anesthesia 58:591-596, 2003. 104. Yeh CC, CT Wu, CH Lu, CP Yang, CS Wong*. Early use of low-dose vasopressin for unstable hemodynamics in acute brain injury patient refractory to catecholamines treatment: A case report. Anesth Analg 97:577-579, 2003. 105. Li CY, Tsai CS, Hsu PC, Chueh SH, Wong CS, Ho ST. Lidocaine attenuates monocyte chemoattractant protein-1 production and chemotaxis in human monocytes: possible mechanisms for its effect on inflammation. Anesth Analg 97:1312-1316, 2003. 106. Chou TC, Chang LP, Li CY, Wong CS, Yang SP. Antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Anesth Analg 97:1724-1729, 2003. 107. Chen CH, Huang GS, Lee CK, Huang YS, Wong CS*. Use of laryngeal mask airway for resuscitation of a Hunter syndrome patient during general anesthesia induction. J Med Sci 23:351-354, 2003. 108. Lu CC, Ho ST, Wong CS, Wang JJ, Tsai CS, Hu OYP, Chang SY, Lin CY. Pharmacokinetics of isoflurane: uptake in the body. Pharmacology 69:132-137, 2003. 109. Lu CC, Ho ST, Wang JJ, Wong CS, Hu OYP, Chang SY, Lin CY. Pharmacokinetics of isoflurane: uptake in the brain. Pharmacology 69:102-107, 2003. 110. Lu CC, Tsai CS, Ho ST, Chen WY, Wong CS, Wang JJ, Hu OYP, Lin CY. Pharmacokinetics of sevoflurane uptake into the brain and body. Anaesthesia 58:951-956, 2003. 111. Wong CS*. Patient safety during anesthesia: the breathing circuit system. Acta Anaesthesiol Sin 41:97-98, 2003. 112. Ger LP, Lee MC, Wong CS, Chao SS, Wang JJ, Ho ST. The effects of education and clinical practice on knowledge and attitudes toward the use of analgesics for cancer pain. Acta Anaesthsiol Sin 41:105-114, 2003. 113. Lin SL, Yeh CC, Lu CH, Ho ST, Wong CS*. Hypercapnia due to rupture of the unidirectional valve in the inspiratory limb of the breathing system after induction of general anestheaia--- a case report. Acta Anaesthesiol Sin 41:139-144, 2003. 114. Wen ZH, Chang YC, Wong CS*. Implications of intrathecal pertussis toxin animal model on the cellular mechanisms of neuropathic pain syndrome. Act Anaesthesiol Sin 41:187-196, 2003. 115. Lu CC, Ho ST, Wang JJ, Wong CS, Tsai CS, Chang SY, Lin CY. Minimal low-flow isoflurane-based anesthesia benefits patients with coronary revascularization via preventing hyperglycemia and maintaining metabolic homeostasis. Act Anaesthesiol Sin 41:165-172, 2003. 116. Cherng CH, Wong CS. Pressure sore induced by epidural catheter in a patient receiving postoperative pain control. Reg Anesth Pain Med 28:580, 2003. 117. Lu CC, Ho ST, Wang JJ, Wang JO, Wong CS, Tsai CS, Chang SY. Minimal low-flow isoflurane-based anesthesia benefits patients undergoing coronary revascularization via preventing hyperglycemia and maintaining metabolic homeostasis. Act Anaesthesiol Sin 41:165-172, 2003. 118. Chou TC, Chang LP, Li CY, Wong CS, Yang SP. The anti-inflammatory and analgesic effects of Baicalin in carrageenan-evoked thermal hyperalgesia Anesth Analg 97:1724-1729, 2003. 119. Wen ZH, Chang YC, Cherng CH, Wong CS*. Increasing of CSF excitatory amino acids concentration by morphine challenge in morphine tolerant rats. Brain Res 995:253-259, 2004. 120. Yang CP, Yeh CC, Wong CS, Wu CT. Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain. Anesth Analg 98:557-558, 2004. 121. Yeh CC, Wu CT, Wong CS*. Vasopressin in acute brain injury: a note of caution: in response. Anesth Analg 98:872-872-3, 2004. 122. Lu CC, Tsai CS, Ho ST, Chueng CM, Wang JJ, Wong CS, Chang SY, Lin CY. Pharmacokinetic of desflurane uptake into the brain and body. Anesthesia 59:216-221, 2004. 123. Hsiung MW, Pai L, Kang BH, Wang BL, Wong CS, Wang HW. Clinical predictors of difficult laryngeal exposure. Laryngoscope 114:358-363, 2004. 124. Huang YS, Shen JT, Lu CH, Ho ST, Wong CS*. Pulmonary aspiration associated with laryngeal mask airway general anesthesia. J Med Sci 24:153-156, 2004. 125. Kou CP, Wong CS, Borel CO, Yang CP, Yeh CC, Lu CH, Wu CT. Cerebrospinal fluid rhinorrhea after thermometer insertion through the nose. Anesth Analg 99:671-619, 2004. 126. Lin SL, Chao PC, Yeh CC, Li CY, Ho ST, Jao SW, Wong CS*. Oral slow release dextromethorphan premedication provides a pethidine spare effect on posthemorrhoidectomy pain management. Acta Anaesthesiol Taiwanica 42:87-91, 2004. 127. Chiao YC, Wong CS*. Opioid Tolerance: Is There a Dialogue between Glutamate and -arrestin? Acta Anaesthsiol Taiwanica 42:93-101, 2004. 128. Kuo HY, Lu CH, Shen YS, Lee SH, Ho ST, Wong CS. Liaw WJ. Fatal hemoptysis after suction through endotracheal tube in a patient with pneumoconiosis – A case report. Acta Anaesthesiol Taiwanica 42:107-110, 2004. 129. Lee HK, Chen CH, Wong CS, Cherng CH, Ho ST, Lu CC, Lee TY. Postoperative transient ischemic attack complicated by CO2 retention and hypoxemia in a patient receiving meperidine injection for postoperative pain relief. Acta Anaesthesiol Taiwanica 42:115-118, 2004. 130. Wu CT, Jao SW, Borel CO, Yeh CC, Li CY, Lu CH, Wong CS. The effect of epidural clonidine on perioperative cytokine response, postoperative pain and bowel function in patients undergoing colorectal surgery. Anesth Analg 99:502-509, 2004. 131. Yeh CC, Wu CT, Wong CS*. In response: Early use of low-dose vasopressin for unstable hemodynamics in acute brain injury patient refractory to catecholamines treatment: A case report. Anesth Analg 98:872-873, 2004. 132. Sung JS, Wen CH, Chang WK, Ho ST, Tsai SK, Chang YC, Wong CS*. Intrathecal interleukin 1 administration induces thermal hyperalgesia by activating inducible intric oxide synthase expression in the rat spinal cord. Brain Res 1015:145-153, 2004. 133. Liaw WJ, Chang BY, Liao RW, Wu CP, Lin TC, Wong CS, Ho ST. Implementation of a clinical information system in surgical intensive care unit: three years experience and outcome. Taiwan Crit Care Med. 6:101-111, 2004. 134. Ou SM, Wan HL, Kuo HY, Lu CH, HO ST, Wong CS, Liaw WJ. Transfusion-related acute long injury. Act Anaesthesiol Taiwanica 42:159-164, 2004. 135. Chung CM, Li CY, Wong CS, Chen FC. Pulmonary edema secondary to the airway obstruction in a patient with Parkinson’s disease. Act Anaesthesiol Taiwanica 42:165-170, 2004. 136. Lu CH, Chao PC, Borel CO, Yang CP, Yeh CC, Wong CS, Wu CT. Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption and improving recovery of bowel function in patients undergoing colorectal cancer surgery. Anesth Analg 99:1466-1471, 2004. 137. Yeh CC, Wu CT, Yu JC, Yang CP, Lu CH, Wong CS*. Effect of combined preincisional treatment of dextromethorphan and tenoxicam on the post-laparoscopic cholecystectomy pain management. Act Anesthesiol Scand 48:1049-1053, 2004. 138. Liaw WJ, Wu CC, Wong CS, Wang JJ, Ho ST. The role of coagulation function in sepsis: disease severity and recent advances in therapy. Taiwan Crit Care Med 6:267-273, 2004. 139. Wu, CT, Wong CS, Yeh CC, Borel CO. Treatment of cerebral vasospasm after subarachnoid hemorrhage- a review. Acta Anaesethesiol Taiwanica 42:215-222, 2004. 140. Chen WY, Lin JA, Chen HL, Wong CS, Ho ST, Lu CC. Pneumothorax associated with tube exchanger-aided intubation following LMA-FasTrach placement in a patient during anesthesia induction – a case report. Acta Anaesethesiol Taiwanica 42:227-231, 2004. 141. Kuo CP, Lu CC, Chueng CM, Lin SL, Wang JJ, Wong CS. Ho ST. Postoperative stroke after dynamic hip screw fixation in a patient with old cerebral infarct and atrial fibrillation. Acta Anaesethesiol Taiwanica 42:223-226, 2004. 142. Huang GS, Li CY, Hsu PC, Tsai CS, Lin TC, Wong CS. Sevoflurane anesthesia attenuates adenosine diphosphae-induced P-selectin expression and platelet-leukocyte conjugate formation. Anesth Analg 99:1121-1126, 2004. 143. Hsieh YC, Liang WY, Tsai SK, Wong CS*. Intrathecal ketorolac pretreatment reduced spinal cord ischemic injury in rats: a pilot study. Anesth Analg 100:1134-1139, 2005. 144. Yang CP, Lee CH, Borel CO, Yeh CC, Lu CH, Wong CS, Wu CT. Postdural puncture headache with abdominal pain and diarrhea: a case report. Anesth Analg 100:879-881, 2005. 145. Jean YH, Wen ZH, Chang YC, Huang GS, Lee HS, Hsieh SP, Wong CS*. Increased concentrations of neuro-excitatory amino acids in rat anterior cruciate ligament-transected knee joint dialysates: a microdialysis study. J Orth Res 23:569-575, 2005. 146. Wen ZH, Wu GJ, Chang YC, Wang JJ, Wong CS *. Dexamethasone modulates the development of morphine tolerance and expression of glutamate transporters in rat. Neuroscience 133:807-817, 2005. 147. Lin TC, Li CY, Tsai CS, Ku CH, Wu CT, Wong CS, Ho ST. Neutrophil-mediated secretion and activation of matrix metalloproteinase-9 during cardiac surgery with cardiopulmonary bypass. Anesth Analg 100:1554-1560, 2005. 148. Lin JA, Wong CS, Cherng CH. Unexpected blood clot-induced acute airway obstruction in a patient with inactive pulmonary tuberculosisduring lumbar spine surgery in the prone position—A case report. Acta Anaesth Taiwanica 43:93-97, 2005. 149. Ho CT, Wu CT, Yeh CC, Yi HD, Wong CS, Yang CP. Postdural puncture arm and upper back pain—A report of two cases. Acta Anaesth Taiwanica 43:123-125, 2005. 150. Yeh CC, Jao SW, Huh BK, Wong CS, Yang CP, White WD, Wu CT. Preincisional dextromethorphan combined with thoracic epidural anesthesia and analgesia improves postoperative pain and bowel function in patients undergoing colonic surgery. Anesth Analg 100:1384-1389, 2005. 151. Sung CS, Wen ZH, Chang WK, Chan KH, Ho ST, Tsai SK, Chang YC, Wong CS*. Inhibition of p38 mitogen-activated protein kinase attenuates interleukin-1-induced thermal hyperalgesia and inducible nitric oxide synthase expression in the spinal cord. J Neurochem 94:742-752, 2005. 152. Cherng CH, Wong CS. Effect of fentanyl on lidocaine-induced convulsions in mice. Pharmacology 75:1-4, 2005. 153. Lin JA, Wong CS, Cherng CH. Unexpected blood clot-induced acute airway obstruction in a patient with inactive pulmonary tuberculosis during lumbar spine surgery in the prone position- a case report. Act Anesthesiol Taiwanica 43:93-97, 2005. 154. Lu CH, Lin SL, Chang FL, Chao PJ, Jao, SW, Wong CS*. Combined general/epidural anesthesia decreased the desflurane requirement for equivalent AAITM index in colon resection surgery patients. Acta Anaesthesiol Scand 49-1603-1607, 2005. 155. Lin JA, Lee MS, Wu CT, Yeh CC, Lin SL, Wen ZH, Wong CS*. Attenuation of morphine tolerance by intrathecal gabapentin is associated with suppression of morphine-evoked excitatory amino acid release in the rat spinal cord. Brain Res 1054:167-173, 2005. 156. Lin JA, Yeh CC, Lee MS, Borel CO, Wong CS*. Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough. Anesth Analg 101:670-674, 2005. 157. Liu SH, Wong CS, Chang DM. Increased monocyte chemoattractant protein-1 in knee joints of rats with adjuvant-induced arthritis: in vivo microdialysis. J Rheumatology 32:220-2211, 2005. 158. Ke YC, Yi HD, Yang CYP, Lee HK, Kuo CP, Wong CS*. Clipping of the appendix induced cardiac arrest during appendectomy under spinal anesthesia. Acta Anaesthesiol Taiwanica 43:183-186, 2005. 159. Tsao CM, Wu CC, Wang JJ, Wong CS, Tsai SK, Ho ST. Intravenous anesthetics in sepsis. Acta Anaesthesiol Taiwanica 43:153-164, 2005. 160. Yeh CC, Wu CT, Huh BK, Yang CP, Wong CS*. Dextromethorphan in the management of acute postoperative pain, a review. Chin J Pain 15:82-91, 2005. 161. Wu GJ, Wen ZH, YC Chang, SN Yang, PL Tao, Wong CS *. Protein kinase C inhibitor chelerythrine attenuates the morphine-induced excitatory amino acid release and reduction of the antinociceptive effect of morphine in rats injected intrathecally with pertussis toxin. Life Sci 78:1801-1807, 2006. 162. Chen WF, Chang H, Huang LT, Lai MC, Yang CH, Wong CS, Yang SN. Alterations in long-term seizure susceptibility and the complex of PSD-95 with NMDA receptor from animals previously exposed to perinatal hypoxia. Epilepsia 47:288-296, 2006. 163. Sheen MJ, Yang CP, Liu YC, Borel CO, Wong CS, Ho ST, Wu CT. Comparing the effects of minimal low-flow desflurane with that of semi-close high flow desflurane on perioperative cytokine response in patients undergoing gastrectomy. Act Anaesthesiol Taiwanica 44:5-10, 2006. 164. Tsung YC, Hsu CH, Lin SL, Wu CT, Yeh CC, Wong CS*. Marcoglossia after posterior fossa surgery in the prone position- a case report. Act Anaesthesiol Taiwanica 44:43-46, 2006. 165. Jean YH, Wen ZH, Chang YC, Le HS, Hseih SP, Wu CT, Yeh CC, Wong CS*. Hyaluronic acid attenuates osteoarthritis development in the anterior cruciate ligament-transected knee: association with excitatory amino acid release in the joint dialysate. J Ortho Res 23:1052-1061, 2006. 166. Wu CT, Fan YM, Sun CM, Borel CO, Yeh CC, Yang CP, Wong CS*. Correlation between changes in regional cerebral blood flow and pain relief in complex regional pain syndrome type I. Clin Nucl Med 31:317-320, 2006. 167. Wong CS*, Kuo CP, Ko SC. Can we do better, in addition to the pharmacological treatment, on pain: collateral meridian therapy. Acta Anaesthesiol Taiwanica 44:59-60, 2006. 168. Horng HC, Chen FC, Ho CC, Huo CP, Wu CT, Wong CS*. Bradycardia and hypotension refractory to ephedrine and atropine treatment: severe autonomic dysfunction with abnormal heart rate variability. Acta Anaesthesiol Taiwanica 44:109-112, 2006. 169. Chen LC, Wong CS, Huh BK, Huang YS, Yang CP, Yeh CC, Wu CT. Repeated lumbar sympathetic blockade with lidocaine and clonidine attenuates pain in complex regional pain syndrome type I patients: a report of two cases. Acta Anaesthesiol Taiwanica 44:113-117, 2006. 170. Tai YH, Wang YH, Wang JJ, Tao PL, Tung CS, Wong CS*. Amitriptyline suppresses neuroinflammation and upregulates glutamate transporters in morphine tolerant rats. Pain 124:77-86, 2006. 171. Lin JA, Borel CO, Wang WB, Wong CS, Yeh CC, Yang CP, Wu CT. Anesthetic management of AAI pacemaker patient with paroxysmal atrial fibrillation during colorectal surgery. J Clin Anesth 18:372-375, 2006. 172. Kuo CP, Jao SW, Chen KM, Wong CS, Yeh CC, Sheen MJ, Wu CT. Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. Br J Anaesth 97:640-646, 2006. 173. Yeh CC, Wu CT, Huh BK, Yang CP, Wong CS*. Dextromethorphan in the management of acute postoperative pain, a review. Chin J Pain 15:82-91, 2006. 174. Su CK, Chung YC, Tseng CL, Wong CS. The recognition, analgesic efficacy and satisfaction of patient-controlled analgesia in postoperative patients. 台灣醫學 10:557-565, 2006. 175. Lu CH, Liu JY, Lee MS, Borel CO, Yeh CC, Wong CS, Wu CT. Preoperative cotreatment with dextromethorphan and ketorolac provides an enhancement of pain relief after laparoscopic-assisted baginal hysterectomy. Clin J Pain 22:799-804, 2006. 176. Kuo CP, Chen KM, Wu CT, Horng HC, Cherng CH, Yu JC, Wong CS*. Utility of the auditory evoked potentials index as an indicator for endotracheal intubation. Act Anaesthesiol Taiwanica 44:205-210, 2006. 177. Cherng CH, Wong CS. Ketamine-induced emergence reactions after desflurane anaesthesia. Eur J Anaesthesiol 24:200-201, 2006. 178. Chen WF, Chang H, Wong CS, Huang LT, Yang CH, Yang SN. Impaired expression of postsynaptic density proteins in the hippocampal CA1 region of rats following perinatal hypoxia. Exp Neurology 204:400-410, 2007. 179. Yeh CC, Wu CT, Huh BK, Lee MS, Lin SL, Sheen MJ, Wong CS*. Premedication with intravenous low-dose ketamine suppresses fentanly-induced cough. J Clin Anesth 19:53-56, 2007. 180. Jean YH, ZH Wen, YC Chang, HS Lee, SP Hsieh, Wong CS*. Intra-articular injection of the cyclooxygenase-2 inhibitor parecoxib attenuates osteoarthritis after anterior cruciate ligament transection: role of excitatory amino acids. Osteoarthris & Cartilage 15:638-645, 2007. 181. Hsieh YC, H Cheng, KH Chan, WK Chang, TM Liu, Wong CS*. Intrathecal ketorolac pretreatment inhibits nitric oxide and excitatory amino acids and protects spinal cord ischemic injury in rats. Acta Anesthesiol Scand 51:410-414, 2007. 182. Wu GJ, Wen ZH, WF Chen, YC Chang, CH Cherng, Wong CS *. The effect of dexamethasone on spinal glutamine synthetase and glutamate dehydrogenase expression in morphine-tolerant rats. Anesth Analg 104:726-730, 2007. 183. Wong CS*, Kuo CP, Fan YM, Ko SC. Collateral meridian therapy dramatically attenuates pain and improves functional activity of a patient with complex regional pain syndrome. Anesth Analg 104:452, 2007. 184. Chen WF, Chang H, Wong CS, Huang LT, Yang CH, Yang SN. Impaired expression of postsynaptic density proteins in the hippocampal CA1 region of rats following perinatal hypoxia. Exp Neurol 204:400-410, 2007. 185. Lin YT, Sheen MJ, Huang ST, Horng HC, Cherng CH, Wong CS, Ho ST. Gabapentin relieves post-dural puncture headache – a report of two cases. Acta Anesthesiol Taiwanica 45:47-51, 2007. 186. Lin BF, Lee SC, Kao CH, Tsung YC, Kuo CP, Wong CS, Wu CT. Subglottic stenosis after thoracotomy – a case report. Acta Anesthesiol Taiwanica 45:59-62, 2007. 187. Lue WM, Huang EYK, Yang SN, Wong CS, Tao PL. Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats. Synapse 61:420-428, 2007. 188. Tai YH, Wang YH, Tsai RY, Wang JJ, Tao PL, Liu TM, Wang YC, CS Wong*. Amitriptyline preserves morphine’s antinociceptive effect by regulating the glutamate transporter GLAST and GLT-1 trafficking and excitatory amino acids concentration in morphine-tolerant rats. Pain 129:343-354, 2007. 189. Song CS, Wong CS*. Cellular mechanisms of neruoinflammatory pain: the role of interleukin-1. Acta Anaesthesiol Taiwanica 45:103-109, 2007. 190. Ho CC, Kuo CP, Huang ST, Cherng CH, Yeh CC, Wong CS, Wu CT. Postoperative pulmonary edema after lower thoracic spinal tumor surgery - A case report. Acta Anaesthesiol Taiwanica 45:103-109, 2007. 191. Lin JA, Chen FC, Lee MS, Hrng HC, Cherng CH, Yeh CC, Wong CS*. Intravenous dexamethasone pretreatment reduces fentanyl-induced cough. J Formos Med Assoc 106:649-655, 2007. 192. Chang FL, Lin SL, Tsai CS, Yeh CC, Wu CT, Shen CT, Wong CS*. Closed-circuit isoflurane-based anesthesia provides better fast-tracking anesthesia than fentanyl/propofol-based anesthesia for off-pump coronary artery bypass surgery. Acta Anaesthesiol Taiwanica 45:135-139, 2007. 193. Chen LC, Tzao C, Liwa WJ, Horng HC, Cherng CH, Wong CS, Wu CT. Pneumomediastinum complicated by subclavian central venous catheterization in a severe thoracic trauma patient. Acta Anesthesiol Taiwan 45:185-188, 2007. 194. Huang YS, Lin LC, Huh BK, Sheen MJ, Yeh CC, Wong CS, Wu CT. Epidural clonidine for postoperative pain after total knee arthroplasty: a dose-response study. Analg Anesth 104:1230-1235, 2007. 195. Horng HC, Wong CS, Hsiao KN, Hun BK, Kuo CP, Cherng CH, Wu CT. Premedication with intravenous clonidine suppresses fentanyl-induced cough. Act Anesthesiol Scand 51:862-865, 2007. 196. Chung YC, Su CK, Wong CS. Study on patient satisfaction with patient-controlled analgesia and related factors after abdominal surgery. J Med Sci 27:207-214, 2007. 197. Chen CM, Chen WH, Wong CS, Wu SS, Wang SJ. Surgical treatment of a pregnant woman with unstable, displaced pelvic and acetabular fractures. Injury Extra 38:405-408, 2007. 198. Wong CS*. A choice of anesthesia technique for cost-effectivness and environmental protection: Target controlled infusion-total intravenous anesthesia. Acta Anaesthesiol Taiwanica 45:195-196, 2007. 199. Horng HC, Kuo CP, Ho CC, Wong CS. Yu MH, Cherng CH, Wu CT. Cost analysis of three anesthetic regimens under auditory evoked potentials monitoring in gynecologic larparoscopic surgery. Acta Anaesthesiol Taiwanica 45:205-210, 2007. 200. Chung YC, SU CK, Wong CS. Study on patient satisfaction with patient-controlled analgesia and related factors after abdominal surgery. J Med Sci 27:207-214, 2007. 201. Lee CC, Huang GS, Lin TC, Lee JC, Wong CS. An epidural blood patch relieves unilateral postdural puncture tinnitus in a post-caesarean section parturient. J Med Sci 27:29-32, 2007. 202. Wang SJ, Wong CS. Extra-articular Knowles pin fixation for unstable distal clavicle fracture. J Trauma 64:1522-1527, 2008. 203. Wang SJ, Wong CS. Transacromial extra-articular Knowles pin fixation treatment of acute type V acromioclavicular joint injury. 65:424-429, 2008. 204. Wen ZH, Wu GJ, Hsu LC, Chen WF, Chen JY, Shui HA, Chou AK, Wong CS*. N-methyl-D-aspartate receptor antagonist MK-801 attenuates morphine tolerance and associated glial fibrillary acid protein up-regulation: a proteomic approach. Acta Anaesthesiol Scand 52:499-508, 2008. 205. Wong CS*, Wu CT. Cost analysis of three anesthetic regimens under auditor evoked potential monitoring in gynecologic laparoscopic surgery. Acta Anesthaesthesiol Taiwan 46:53-54, 2008. 206. Huang ST, Kuo CP, Chen JC, Wu CT, Heish CM, Wong CS, Yeh CC. Successful cardiopulmonary resuscitation in a morbidly obese patient with airway obstruction 10 days after trachesotomy. Acta Anesthaesthesiol Taiwan 46:30-33, 2008. 207. Tai YH, Tsai RY, Wang YH, Cherng CH, Tao PL, Liu TM, Wong CS*. Amitriptyline induces nuclear transcription factor-κB-dependent glutamate transporter upregulation in chronic morphine-infused rats. Neuroscience 153:823-831, 2008. 208. Lu CH, Ou-Yang HY, Man KM, Hsiao PC, Ho ST, Wong CS, Liaw WJ. Relative reliability of the auditory evoked potential and bispectral index for monitoring sedation level in surgical intensive care patients. Anaesth Inten Care 36:553-559, 2008. 209. Yeh CC, Lin JA, Kou CP, Wu CT, Ko SC, Wong CS*. Shoulder-tip Pain Following Laparoscopic Surgery Analgesia by Collateral Meridian Acupressure (Shiatsu) Therapy--Report of two cases. J Manipula Physiol Therap 31:484-488, 2008. 210. Lin JA, Tsai RY, Lin YT, Lee MS, Cherng CH, Wong CS*, Tzeng JI. Amitriptyline pretreatment preserves the antinociceptive effect of morphine in pertussis toxin-treated rats by lowering CSF excitatory amino acid concentrations and reversing the downregulation of glutamate transporters. Brain Res 1323:61-69, 2008. 211. Tsai RY, Jang FL, Tai1 YH, Lin SL, Shen CH, Wong CS*. Ultra-low-dose naloxone restores the antinociceptive effect of morphine and suppresses spinal neuroinflammation in PTX-treated rats. Neuropsychopharmacology 33:2772-2782, 2008. 212. Jean YH, Wen ZH, Chang YC, Hsieh SP, Lin JD, Tang CC, Chen WF, Chou AK, Wong CS*. Increase in excitatory amino acid concentration and transporters expression in osteoarthritic knees of anterior cruciate ligament transected rabbits. Osteoarthritis Cartilage 16:1442-1449, 2008. 213. Chan SM, Huang ST, Wu CT, Cherng CH, Wong CS Ho ST, Lu CH. Perioperative anapyylaxis presented with high peak airway pressure. J Med Sci 28:259-262, 2008. 214. Tsai RY, Tai YH, Tzeng JI, Lin SL, Shen CH, Yang CP, Hsin ST, Wang CB, Wong CS. Ultra-low dose naloxone restores the antinociceptive effect of morphine in pertussis toxin-treated rats and prevents glutamate transporter downregulation by suppressing the p38 mitogen-activated protein kinase signaling pathway. Neuroscience 159:1244-1256, 2009. 215. Chan SM, Horng HC, Huang ST, Ma HI, Wong CS, Cherng CH, Wu CT. Drug cost analysis of three anesthetic regimens in prolonged lumbar spinal surgery. J Med Sci 29:75-80, 2009. 216. Tai YH, Tsai RY, Lin SL, Yeh CC, Wang JJ, Tao PL, Wong CS. Amitriptyline suppresses neuroinflammation-dependent interleukin-10-p38 mitogen-activated protein kinase-heme oxygenase-1 signaling pathway in chronic morphine infused rats. Anesthesiology 110:379-389, 2009. 217. Chuang FP, Chan WK, Chen YH, Wong CS, Chern HD. Nurturing the clinical research leaders of tomorrow. Drug Info J 43:365-369, 2009. 218. Chang FL, Lu CH, Yeh CC, Wu CT, Cherng CH, Wong CS*. Lateral position and one-lung ventilation decrease exhaled nitric oxide concentration during thoracic surgery. Submitted to Anesth Intens Care (in revision). 219. Yeh CC, Lin JA, Huh B, Huang SJ, Ko SC, Wong CS*. Introduction of a modified needleless acupressure treatment for pain management: collateral meridian therapy. Submitted to J Manip Physiol Ther 220. Lu CH, Wu CT, Liaw WJ, Yeh CC, Cherng CH, Wong CS*. Association of composite auditory evoked potential index with epidural neuraxial blockade-dependent sedation in surgical intensive care patients. Anesth Analg (in revision) 221. Wen ZH, Yeh CC, Chang YC, Cherng CH, Wong CS. NMDA receptor antagonist D-AP5 prevents pertussis toxin induced alterations in the rat spinal cords by inhibiting the increasing of spinal CSF excitatory amino acids concentration and down-regulation of glutamate transporters GLAST, EAAC1 and GLT-1. Submitted to Brain Res Bull Wong CS*: corresponding author