June, 2012 CURRICULUM VITAE Yael Ungar PhD 210 Atzmon, Misgav, Israel. 050-4041336 uyael@braude.ac.il PROFESSIONAL EXPERIENCE: 2012-present Lab manager, Prof.Ephraim Katzir Department of Biotechnology Engineering, ORT Braude College, Karmiel, Israel. Managing laboratories for biotechnology students, involved in department research activities, in charge of commercial biotechnology projects, in charge of acquisitions and department facilities. 2010-2012 Lab manager in Prof. Eyal Shimoni’s laboratory, Department of Biotechnology and Food Engineering, Technion, Haifa, Israel. Managing research projects including EU projects and with the Israeli industry. In charge of collaboration between the Technion team and European partners and representing the Technion in EU meetings. Involved in writing grants, scientific papers and progress reports. In charge of group research activities, PhD and MS research projects and supervision of undergraduate students. 2005-2010 Researcher and project manager in Prof. Eyal Shimoni’s laboratory (Post doctoral fellow). 2001-2005 PhD (D.Sc) studies and instructor, Department of Biotechnology and Food Engineering, Technion, Haifa, Israel. 1996-1999 M.Sc studies and instructor, Department of Biochemistry, Food Science and Nutrition, Faculty of Agriculture, Food and Environmental Quality Sciences of the Hebrew University of Jerusalem, Rehovot, Israel. TEACHING EXPIRIENCE: 2001-2005 Food chemistry a laboratory course for undergraduate, Department of Biotechnology and Food Engineering, Technion, Haifa, Israel. 2001-2005 Analytical chemistry a laboratory course for undergraduate Department of Biotechnology and Food Engineering, Technion, Haifa, Israel. 1996-1999 General chemistry for undergraduates, Department of Biochemistry, Food Science and Nutrition, Faculty of Agriculture, Food and Environmental Quality Sciences of the Hebrew University of Jerusalem, Rehovot, Israel. EDUCATION: 1. 2001-2005 D.Sc. in the Faculty of Biotechnology and Food Engineering, Technion, Haifa, Israel. Title: Degradation and modification of soy-isoflavones and the effects on their bioavailability and bioactivity. Supervisor: Prof. Eyal Shimoni. 2. 1996-1999 M.Sc. Agrcum laude in the Department of Biochemistry, Food Science and Nutrition, Faculty of Agriculture, Food and Environmental Quality Sciences of the Hebrew University of Jerusalem, Rehovot, Israel. Title: Physical properties of dry hydrocolloid cellular matrices embedded beads. Department of Biochemistry, Food Science and Nutrition. Supervisor: Prof. Amos Nussinovitch. 3. 1992-1995 B.A in the Faculty of Chemistry, Technion, Haifa, Israel. PROFESSIONAL SKILLS: Food engineering and biochemistry, including: Chromatography detection and characterization methods : HPLC, HPLC/MS, GC, GC/MS Micro and Nano-encapsulation Technologies: Freeze-freeze system, Fluidized bed system, starch encapsulation technologies In vivo experiments in animals Animal tissue culture techniques Food mechanical characterizations techniques RESEARCH AND DEVELOPMENT PROJECTS: I have been involved and managed various projects. Many of these projects were funded by the industry and thereforepartially described due to confidentiality. Among these projects are: Active multilayer packaging based on optimized PLA formulation for minimally processed vegetables and fruits: developing a new degradable packaging for fresh cut vegetables which contains antimicrobial microcapsules. In charge of the micro-encapsulation development and the analytical team. (Part of a FP7- EU project) A system for oral delivery of Insulin: developing insulin capsules using the freeze- freeze drying method, and testing their absorption in the lower duodenum in large animals.(including pre-clinical trials in large animals). Encapsulation of volatile coffee aroma ingredients(funded by the industry) Development of a new gum base formula (funded by the industry). QTL detection for mastitis resistance and milk nutritional aspects in dairy cattle populations in Israel and Italy: fatty acid determinations in milk by GC (managing the analytical team). (Funded by cattle breeders associations) Degradation and modification of soy-isoflavones(in models and products): degradation kinetics, isolation and characterizing products of the degradation reactions, evaluation of thermal treatments effects on the biological bioactivities, antioxidants and anticancer properties of the isoflavones using in vitro and in vivo (cell culture) methods. Encapsulation of biologically active chemicals for oral delivery(several projects):Microcapsules for the protection and controlled release of robotic bacteria, and bioactive molecules, i.e. fatty acids (CLA, Butyric Acid), and Allicin. Identification of LC-PUFA in human breast milk beyond one year of breast feeding: fatty acid (DHA and EPA) in human milk determined by GC. A project done in collaboration with Tel–Aviv Sourasky Medical Center. LANGUEGES: Hebrew and English in mother tongue level. LIST OF PUBLICATIONS: 1. Hagar Ades, Ellina Kesselman, Yael Ungar, and Eyal Shimoni. Complexation with starch for encapsulation and controlled release of menthone and menthol. Food Science and Technology - LWT. (accepted) 2011. 1. Ronit Lubetzky, Galit Zeidenberg-Israeli, Francis B. Mimouni, Shaul Dollberg, Eyal Shimoni, Yael Ungar, Dror Mandel. Human milk fatty acids profile changes during prolonged lactation: a cross sectional study. IMAJ, (accepted) 2011. 2. Roy Ramon, Nor Salzmann, Yael Ungar, Ehud Zip and Eyal Shimoni, Per-oral testing of a novel timed release formulation for a burst type oral delivery of insulin, 2009 (to be published). 3. Recital Cohen, Ivgenia Orlova, Marina Kovalevsky, Yael Ungar and Eyal Shimoni, Structural and functional properties of amylase complexes with genistein, J. Agric. Food Chem. 56 (11), 4212-4218, 2008. 4. Alina Marchevski, Asher Shazaman, Yael Ungar and Eyal Shimoni. Reducing the formation of glucose degradation products in peritoneal dialysis solutions by ultrahigh temperature ohmic heating. Molec Nutr Food Res. 51 (4): 473-478, 2007. 5. Shimoni, E., Lesmes, U. and Ungar, Y., Non-covalent nanocomplexes of bioactive agents with starch for oral delivery. U.S. Provisional Patent Application TECH/004, 2006. 6. Y. Ungar and E. Shimoni. Phytoestrogens and the prevention of cancer, in: Functional foods, ageing and degenerative disease, C. Remacle and B. Reusens eds., Woodhead Publ. Ltd, Cambridge, UK. Pp.645-668, 2004. 7. Yael Ungar, Oluwatooyin F. Osundahunsi, and Eyal Shimoni. Thermal stability of genistein and daidzein and its effect on their antioxidant activity. J. Agric. Food Chem. 51 (8): 2232-2236, 2003. 8. B. Eisen, Y. Ungar, and E. Shimoni. Stability of isoflavones in soy milk stored at elevated and ambient temperatures. J. Agric. Food Chem. 51(8): 2212-2215, 2003. PARTICIPATION IN CONFERENCES: 1. The QuaLAT Project: Mapping QTL for SCC and Milk Fatty Acid Content in the Italian Brown Population and in the Israel Holstein Friesian. F. Schiavini 1, A.B. Samoré1, A. Rossoni2, Y. Ungar3, Y. Kashi3, E. Shimoni3, R. Tal4, E. Lipkin4, M. Soller4, Abraham Korol5, Zeev Frenkel5 and A. Bagnato1 1Dipartimento di ScienzeTecnologieVeterinarie per la Sicurezza Alimentare, UniversitàdegliStudi di Milano, AssociazioneNazionaleAllevatoriRazzaBruna, Faculty of Biotechnology & Food Engineering, The Technion - Israel Institute of Technology, Haifa, Israel, Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel. Plant and Animal Genome XVII Conference, January 10-14, 2009, San Diego, CA, USA. 2. R. Cohen, Y. Orlova, M. Kovalev, Y. Ungar, U. Lesmes and E. Shimoni. Encapsulation genistein in amylose complexes .XVIth International Workshop on Bioencapsulation, Dublin, Ireland, September, 2008. 3. Y. Ungar and E. Shimoni. Microcalorimetric stability testing of soy-isoflavones. New Functional Ingredients and Foods conference, Copenhagen, Denemark, April 2003. 4. B. Eisen, Y. Ungar, E. Shimoni. Genistin stability in soy milk. New Functional Ingredients and Foods conference, Copenhagen, Denemark, April 2003. 5. Y. Ungar and E. Shimoni. Thermal stability of genistein and daidzein and its effect on their antioxidant activity. Annual Meeting of the Israeli Society of Oxygen and Free Radicals, Naharia, Israel, December 2002. 6. Y. Ungar and A. Nussinovitch. Composite cellular carriers. BioencapsulationVII, Easton, MD, USA, November 1998. 7. Y. Ungar, G. Regev, A. Nussinovitch. Dry cellular macrocapsules, BioencapsulationVII, Easton, MD, USA, November 1998.