Physiology 1
Los Angeles Mission College
Life Sciences Department
Spring 2010
Introduction to Human Physiology
COURSE SYLLABUS
Instructor:
Time:
Mo Elkerdany, DDS, PhD
4 UNITS
M, W 6:55-8:20 p.m. (LECTURE)-Sections 3410 and 3411 Place: INST-2001
M, W 5:20-6:45 p.m.(LAB)- Section 3410 INST-2018
M, W 8:30-9:55 p.m. (LAB)-Section 3411 INST-2018
TEXTBOOK:
Human Anatomy & Physiology
9th Edition
Elaine N. Marieb
LAB MANUAL: Human Anatomy & Physiology Laboratory Manual
9th Edition.
PhysioEX VERSION 5.0
Elaine N. Marieb
COURSE DESCRIPTION:
Lecture 3 hours + Lab 3 hours
The student will learn to describe the major functional characteristics of the HUMAN BODY and relate
these functions to the structure of cells, tissues and organs comprising the following systems: Skeletal,
Muscular, Nervous, Circulatory, Respiratory, Digestive, Urinary, Endocrine, and Reproductive. This
INTRODUCTORY HUMAN PHYSIOLOGY course explains how the HUMAN BODY works with
emphasis on its clinical implications. The contents of the course serve students in different majors.
Prerequisite: College-level Biology course with Laboratory and Introductory Human Anatomy course with
Laboratory.
COURSE OBJECTIVES:
Upon completion of this course, the student will be able to identify and describe the basic functions of the
HUMAN BODY through concepts of organ and system structure in relation to their functions.
Teaching Methods: I will lecture most of the time. I am open to questions during lectures.
There will be occasional group discussion and study sessions for problem solving and
critical thinking. My goal is to insure instruction that provides systematic development of your
academic skills to meet high academic standards. Comprehensive instructional design to
accommodate the different needs will be used, including a variety of teaching techniques,
strategies and learning methods.
“..Teachers lead students to the threshold of their own mind..”
Office Hours: M, W 3:15- 5:15 pm Room: 32 @ Faculty Offices-INST
T,TH
5:15-6:00 p.m.
Telephone:
(818) 833-3411
Web page: http://www.lamission.edu/~elkerdmk
E-mail: elkerdany@att.net
elkerdmk@lamission.edu
Page 2
I will be available during my office hours to discuss any of your concerns and answer your questions about
course content or requirements. You may also leave a message for me at any time or send me E-mail, and I
will get back to you ASAP!
Evaluation Methods: I assume that you want to do well on exams and you want to understand
and enjoy this Human Physiology course. In order to get the most out of it, please plan to
spend enough time studying. You are expected to read assigned material in advance of the lecture
in which the material will be discussed. Evaluation methods may include standardized tests, short
essay tests, quizzes, and a comprehensive final examination. Multiple Choice, True-False, and
Matching questions will be used for midterm and final exams. A schedule of lectures and
exams is attached. I encourage taking notes during my lectures, and I recommend using the
Study Guide and CD-ROM that accompany the textbook to prepare for your exams. The
Textbook is a primary source of information to complement my presentations and to reinforce
the content of the lectures. Attendance is Mandatory!! If you miss a class, you are responsible of
obtaining lecture notes and assignments from another student in the class.
Lecture Grades:
4 Lecture Exams
300 points
Each exam will cover one part the course as discussed in the class and the textbook.
NO final examination.
Exams are NOT made-up. You must have a very valid excuse to miss an exam. Your make-up
exam will be different than the test given for the class. Your make-up exam would be an Essay
type of exam or an Oral exam.
Lab Grades:
Lab Reports, assignments, and QUIZZES…
100 points
PARTICIPATION/ATTENDANCE
50 points
Final Lab Practical Test / Problem Based Learning..
50 points
Regular attendance, professional conduct, Collaborative learning,
and active participation in class are MANDATORY!!
TOTAL Points
300 pts (lecture) + 200 pts (lab) = 500 points
Final Grade: The final grade is based on the percentage of the total number of points earned
in the course. The grade range is usually as follows:
A = 90-100%
less than 60%
B = 80-89%
C = 70-79%
D = 60-69%
F=
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Spring 2010
Dr. Mo Elkerdany
Physiology 1
LECTURE SCHEDULE
________________________________________________________________________
WEEK
TOPIC
CHAPTER
1
Introduction to HUMAN PHYSIOLOGY.
Levels of Organization of the human body. Homeostasis.
Necessary Life Functions. Homeostatic Control Mechanisms.
Chemistry of the body. Acids, Bases, Buffers, and pH scale.
Carbohydrates, Lipids, Proteins, and Nucleic Acids & ATP.
1
2
CELLS. Functions of the cell structures.
Membrane Transport: Passive Processes and Active Processes.
3
3
Physiology of MUSCLE. Types of muscle tissue.
Functions and Characteristics of Muscle Tissue.
Sliding Filament Mechanism of CONTRACTION.
Metabolism of muscle. Muscle Twitches and Summation.
9
4
Nervous System and Nervous Tissue.
Organization of the NERVOUS SYSTEM.
Neurophysiology: Nerve Conduction & Nerve Transmission.
Temporal Summation. Spatial Summation.
Peripheral Nervous System & Reflex Activity.
Cranial Nerves and their functions.
Components of a REFLEX ARC. Spinal Reflexes.
4
5
6
Physiology of Autonomic Nervous System.
2
11
13
14
1st Exam (3/17/10)
7
ENDOCRINE SYSTEM. Mechanism of hormone action.
Major Endocrine Glands and their HORMONES.
8
--------------------------SPRING BREAK-------------------------------------------
9
BLOOD. Composition and Functions of blood.
Hemostasis/Blood Clotting Factors.
Human Blood Groups. Blood Typing.
16
17
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Physiology 1 Lecture Schedule
WEEK
9
10
Dr. Mo Elkerdany
TOPIC
CHAPTER
Cardiovascular System: HEART.
Pathway of blood through the heart.
Functions of the Heart Valves. Heart Physiology.
18
Cardiovascular System: Blood Vessels.
Physiology of CIRCULATION.
Pulmonary Circulation and Systemic Circulation.
19
2nd Exam (4/14/10)
11
12
13
14
14
15
16
Respiratory System.
Principal Organs of the Respiratory System and
Their FUNCTIONS. Mechanics of BREATHING.
Lung Capacity, Respiratory Volumes and Pulmonary
Function Tests.
DIGESTIVE SYSTEM.
GI Tract, Accessory Digestive Organs and
Their FUNCTIONS. Mechanical and Chemical
DIGESTION of food.
NUTRITION: Essential Nutrients.
Role of Vitamins and Minerals.
22
23
24
3rd Exam (5/12/10)
URINARY SYSTEM.
Physiology of EXCRETION: Mechanisms of
Urine formation.
REPRODUCTIVE SYSTEM.
Physiology of REPRODUCTION.
Spermatogenesis. Oogenesis & Reproductive Cycle.
PREGNANCY & HUMAN DEVELOPMENT
Fertilization. Early Embryonic Development
Review for Final Exam
25
27
28
4th Exam (5/24/10)
Important Dates: Drop classes without incurring fees…..2/22/2010
Drop classes without receiving a “W”.. 3/5/2010
Drop classes with a “W”……………… 5/7/2010
Spring Break (3/29-4/5/2010), Final Exams (June 1 to June 7, 2010).
Have a Great Semester
Mo K. Elkerdany, DDS, PhD
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STUDENT LEARNING OUTCOMES
Upon completion of this course, the successful student should be able to:
1. Describe what is meant by the term homeostasis and provide examples of positive and negative
feedback mechanisms in the human body.
2. Explain how a membrane potential is established in a cell, and the importance of membrane potentials
in the function of three different organs.
3. Describe how a muscle cell contracts at the level of the sarcomere.
4. Define a motor unit, and explain how gradual activation of motor units cause gross muscular function.
5. Explain the role of Na+, K+, and Cl- ions in the electrical activity of a neuron.
6. Describe how neurotransmitters have an effect on a target cell.
7. Draw a classic patellar tendon reflex arc and label all of the parts.
8. Describe the functional differences between rods and cones in visual perception.
9. List the structures involved in visual perception from the retina to the primary visual cortex, and
describe symptoms that would result to lesions in each structure.
10. Explain at least three different causes for a patient to suffer from anemia.
11. Describe the value of a differential WBC count in the diagnosis process.
12. Identify the patterns on an EKG and link them to the events of the cardiac cycle.
13. Describe the flow of blood through the heart.
14. Explain the different aspects of the non-specific immune response.
15. Explain the humoral immune response, including clonal selection and immunologic memory.
16. Describe the role of T-cells in cellular immunity.
17. Identify the major physical factors that play a role in the blood pressure of a patient.
18. Describe the events of passive and active inspiration and expiration.
19. Explain the effects of temperature, pH, and DPG on the binding affinity of hemoglobin for oxygen.
20. Explain the importance of the carbonic acid / bicarbonate buffer system in carbon dioxide transport
and pH regulation.
21. Explain the roles of the small intestine and large intestine in the digestive process.
22. Draw a nephron, label all of the parts, and describe the action of each of the tubules in the formation
of urine.
23. Describe how the circulatory system and excretory system are intimately linked, using regulation of
blood pressure as an example.
24. Compare and contrast spermatogenesis and oogenesis in their timing, location, and meiotic divisions.
25. Explain the role of GnRH, FSH, LH, estrogen, and progesterone in the regulation of the ovarian and
uterine cycles.
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Physiology 1
Dr. Mo Elkerdany
Laboratory Schedule
Spring 2010
Monday & Wednesday Lab (Sections 3410 and 3411)
WEEK
Lab TOPIC
Lab EXERCISE
1
Scientific Method, Scientific
Preface of Lab Manual
Notation, Metrics.
Cell Transport and PermeabilityWet Lab. Transport Mechanisms and PermeabilityMuscle Physiology.
Biopac-Basic Student Tutorial
2
3
3
5A
16A
page 591
PhysioEX……. 5B
Skeletal Muscle Physiology- PhysioEX…. 16B
Biopac-Electromyography I- Standard and Integrated EMG
4
4
5
Biopac- Electromyography II- Motor Recruitment and Fatigue
Human Reflex Physiology
Cardiovascular Physiology….. .. 34B
Biopac- Electroencephalography I- EEG of Brain Rythms
Blood
Blood Analysis- PhysioEX…… 29B
6
7
8
20
29A
----------------------------- Spring Break -----------------------------
9
Biopac - Electrocardiography I
Cardiovascular Dynamics- PhysioEX….33B
Frog Cardiovascular Physiology- PhysioEX…34B
Biopac- Pulmonary function I
Respiratory System Mechanics- PhysioEX…37B
NeuroPhysiology of Nerve Impulses
PhysioEX…..18B
Chemical Digestion of food: Enzymatic Action
Chemical and Physical processes of DigestionPhysioEX… 39B
Urinalysis
Renal Physiology-The function of the NephronPhysioEX..41B
Endocrine System PhysiologyPhysioEX…. 28B
Physiology of ReproductionGametogenesis. Human Development.
Sea Urchin’s Fertilization Live Experiment- Wet Lab.
Final Lab Practical Exam. Wednesday, May 26, 2010
10
11
12
13
14
15
16
Important Notes:
*Biopac Lab Exercises will be assigned for some scheduled labs.

22
Lab Quizzes date and time will be announced in class.
39A
41A
43
44
Page 7
Academic Honor Code
Los Angeles Mission College
Departments of Physical and Life Sciences
Students at Los Angeles Mission College, because they are members of an academic community dedicated to the achievement
of excellence, are expected to meet high standards of personal, ethical, and professional conduct. These standards require
personal integrity and a commitment to honesty. Without the ability to trust in these principles, an academic community and a
civil society cannot exist. Los Angeles Mission College faculty and staff are as committed to the development of students with
honesty and integrity as they are to their academic and professional success.
The Academic Honor Code is an undertaking of the students, both individually and collectively, that they will:
1.
not give or receive unpermitted aid during exams, quizzes, assignments or any other course work that is to be used by the
instructor as a basis for grading.
2.
do their share and take an active part in upholding both the spirit and letter of the Academic Honor Code.
Some examples of conduct that are regarded as being in violation of this trust include:

Copying from another’s examination or quiz or allowing another to copy from one’s own papers

Using any unpermitted source of information, human or other, during an exam, quiz or assignment that influences the
grade; this includes the use of technological devices

Any student-to-student collaboration that is unpermitted

Plagiarism (plagiarism is defined as the use, without giving reasonable and appropriate credit to, or acknowledging the
author or source, of another person's original work)

Representing as one’s own work as the work of another

Giving or receiving aid on an academic assignment under circumstances in which a reasonable person should have
known that such aid is not permitted
As a part of the effort to promote and instill an environment of honesty and integrity during quizzes and examinations, the
following guidelines will apply for any courses in the Departments of Physical and Life Sciences:
1.
Students will leave all books and all other non-essential items (e.g. paper, electronic devices) on the floor or inside their
backpacks so that they are not useable nor block the sight line between professor and student. No electronic devices will be
in reach.
2.
Students will not communicate in any way that will dishonorably assist themselves or another student.
3.
Students will leave the room during an exam only if permitted by the professor’s policy. If permitted, only one student
may leave the room at any time and be gone for only the average length of time needed for the stated purpose. Students
will leave all purses, bags, books, phones, jackets, etc., in the classroom during the absence.
4.
Students will support and promote the Academic Honor Code by dissuading fellow students from dishonest activity and,
when such casual persuasion does not work, informing the professor of the possible dishonest activity, either anonymously,
or otherwise.
5.
Students will make every effort to avoid the appearance of dishonesty or lack of integrity
Violation of this policy will not be tolerated and violators will be subject to penalties. The success of the Academic
Honor Code is based upon the collective desire of students, faculty and the community to live in an environment that
embraces respect for that which is right – both in the college and in society as a whole.