15th Annual Symposium
Visual Sciences Research Center
Schedule
Friday, June 21, 2013
8:00
Continental Breakfast, Poster Setup
8:40
Jonathan H. Lass, M.D.
Charles I Thomas Professor and Chairman, Ophthalmology & Visual Sciences
Opening Remarks
8:45
Eric Pearlman, Ph.D.
Silvia Page-William J. Reinhart, M.D. Professor
Director of Research, Ophthalmology & Visual Sciences
Update on Visual Sciences Research Center
Molecular Biology of Vision Moderator: Johannes Von Lintig, Ph.D.
8:55
Grzegorz Palczewski
VSRC Training Grant Recipient, Ophthalmology & Visual Sciences
Johannes Von Lintig , Ph.D. Lab
Evidence for Compartimentilization Based Regulation of Carotenoid Metabolism
9:10
Nathan Alexander, Ph.D.
VSRC Training Grant Recipient, Ophthalmology and Visual Sciences
Krzysztof Palczewski, Ph.D. Lab
Adaptive optics with two-photon fluorescent microscopy allows in vivo imaging of retina cells
9:25
Allison Whited, Ph.D
VSRC Training Grant Recipient, Ophthalmology and Visual Sciences
Paul Park, Ph.D. Lab
Atomic force microscopy-based characterization of human and mouse rhodopsin in native disc
membranes
9:40
Yoshikazu Imanishi, Ph.D.
Assistant Professor, Pharmacology
Trafficking and mis-trafficking of membrane proteins in rod photoreceptors
Introduction: Jonathan H. Lass, M.D.
9:55
Keynote Speaker
Thaddeus Dryja, M.D.
VP & Global Head of Ophthalmology Research
Department of Ophthalmology and Visual Sciences
I 216.368.4752
I www.case.edu/med/ophthalmology
Novartis Institutes for Biomedical Research, Inc.
Cambridge, Massachusetts
The physician-scientist in pharmaceutical research
Molecular Pathogenesis I - Moderator: Paul Park, Ph.D.
10:15
Aicha Saadane, Ph.D.
Research Associate, Ophthalmology and Visual Sciences
Irina Pikuleva, Ph.D. Lab
Impaired oxysterol production causes diabetic-like microangiopathy in normoglycemic mice
10:30
Rooban Nahomi, Ph.D.
Postdoctoral Researcher, Ophthalmology & Visual Sciences
Ram Nagaraj, Ph.D. Lab
Chaperone peptides of α-crystallin inhibit cataract formation in rats
10:45
Patricia Taylor, Ph.D.
Postdoctoral Fellow, Ophthalmology & Visual Sciences
Eric Pearlman, Ph.D. Lab
ROR-gamma-T expressing neutrophils produce IL-17 and express IL-17RC in response to IL-6 and IL-23
during fungal Keratitis
11:00
David Bardenstein, M.D.
Assistant Professor, Ophthalmology
Histopathology & Immunopathology of the Eye in Blau's Syndrome: First cases
11:15
Akiko Maeda, M.D., Ph.D.
Assistant Professor, Ophthalmology & Visual Sciences
Retinal inflammation in mouse models with retinal degeneration
11:30
Vincent Monnier, M.D., Ph.D.
Professor, Pathology
The Role of Protein Oxidation in the Formation of Nuclear Cataracts in Mice and Men
11:45 – 1:15 Lunch & Poster Session
Genetics and Genomics - Moderator: Sudha Iyengar, Ph.D.
1:15
Lakshmi Pulagam, Ph.D.
Research Associate, Epidemiology & Biostatistics
Sudha Iyengar, Ph.D. Lab
Refining genetic discoveries in AMD with genomics
1:30
Sarah Smith, M.D.
Resident, Ophthalmology & Visual Sciences
Characterizing the TCF4 gene region in cases and controls with Fuchs’ Endothelial Corneal Dystrophy
(FECD)
Department of Ophthalmology and Visual Sciences
I 216.368.4752
I www.case.edu/med/ophthalmology
Introduction: Sudha Iyengar, Ph.D.
1:45
Keynote Speaker
Michael Gorin, M.D., Ph.D.
Harold and Pauline Price Professor of Ophthalmology
Professor of Human Genetics
Chief of Retinal Disorders and Ophthalmic Genetics Division
Co-Director, Visual Physiology Laboratory
Jules Stein Eye Institute
University of California Los Angeles
Translating the genetics of age-related macular degeneration into clinical practice
Molecular Pathogenesis II - Moderator: Carlos Subauste, M.D.
2:45
Keynote Speaker
Thaddeus Dryja, M.D.
Complement and age-related macular degeneration
3:45
Luis Muniz Feliciano
VSRC Training Grant Recipient, Ophthalmology & Visual Sciences
Carlos Subauste, M.D. Lab
Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the
parasite
4:00
Zili Zhang, M.D., Ph.D.
Associate Professor, Pediatrics
Low Dose Rapamycin Exacerbates Autoimmune Experimental Uveitis In Part via an
Autophagy-mediated Mechanism
4:15
Elizabeth Liu
VSRC Training Grant Recipient, Ophthalmology & Visual Sciences
Carlos Subauste, M.D. Lab
The autophagy protein Atg5 but not Atg7 promotes presentation of Toxoplasma gondii antigens
4:30
Chairut Vareechon
VSRC Training Grant Recipient, Ophthalmology & Visual Sciences
Eric Pearlman, Ph.D. Lab
Characterization of PMN-17 in the peripheral blood of patients with fungal corneal ulcers
4:45
Poster Session & Reception____________________________________________________
Saturday, June 22
8:00
Continental Breakfast
Department of Ophthalmology and Visual Sciences
I 216.368.4752
I www.case.edu/med/ophthalmology
8:20
Jonathan Lass, M.D.
Opening Remarks
Posterior Segment: Shawn Wilker, M.D.
8:23
Tristan Levey
Medical Student, Case Western Reserve University School of Medicine 2015
Suber Huang, M.D., M.B.A. Lab
Hyperfluorescent perivascular rings on fluorescein angiography in neovascular AMD following antiVEGF treatment
8:35
Joseph Nezgoda, M.D.
Resident, Ophthalmology & Visual Sciences
Comparison of Spectral Domain Optical Coherence Tomography with Clinical Exam Findings in
Choroidal Melanocytic Lesions
8:47
Marina Eisenberg, M.D.
Resident, Ophthalmology & Visual Sciences
Response to aflibercept after tachyphylaxis to ranibizumab and bevacizumab in a patient treated for
exudative age-related macular degeneration
8:59
Camille Palma, M.D.
Resident, Ophthalmology & Visual Sciences
Primary ocular lymphoma in a family with history of Hodgkin's and Non-Hodgkin's lymphoma: a case
9:11
Keynote Speaker
Michael Gorin, M.D., Ph.D.
Diagnostic and Therapeutic Approaches for Hereditary Retinopathies
9:45
Break
Anterior Segment: Pankaj Gupta, M.D.
10:00
Reena Vaswani, M.D.
Resident, Ophthalmology & Visual Sciences
Iris Melanoma induced glaucoma treated with canaloplasty
10:12
Christine Marchetti, M.D.
Resident, Ophthalmology & Visual Sciences
Corneal Stroma and Endothelial Cell Changes in Contact Lens Wearers Visualized with Confocal
Microscopy
10:24
O’Rese Knight, M.D.
Resident, Ophthalmology & Visual Sciences
A Randomized Prospective Masked Clinical Trial of Optisol GS vs. Life4C Storage Media
10:36
Chau Pham
Department of Ophthalmology and Visual Sciences
I 216.368.4752
I www.case.edu/med/ophthalmology
CWRU SOM ‘13
Donor Endothelial Specular Image Quality in Optisol GS and Life4˚C
10:48
Jessica Lee, M.D.
Resident, Ophthalmology & Visual Sciences
In vivo confocal microstructural analysis of corneal epithelial cell changes related to daily wear use of
silicone hydrogel contact lenses
11:00
Lynn Zhang, M.D.
Resident, Ophthalmology & Visual Sciences
Femtosecond laser assisted cataract surgery outcomes
11:12
Karen Rudo, M.D.
Resident, Ophthalmology & Visual Sciences
Resident cataract surgery refractive outcomes with toric intraocular lenses
11:24
Tamar Shafran, M.D.
Resident, Ophthalmology & Visual Sciences
Micro-surgical curriculum: Achieving surgical competencies at each stage of residency training
11:36
Homaira Hossain, MD
Resident, Ophthalmology & Visual Sciences
Pediatric Inpatient Ophthalmology Consultations
11:48
Jonathan Lass MD
Concluding remarks
12:00-3:00
Resident Graduation: Dr. Jonathan Lass, Marianne Reeves
Department of Ophthalmology and Visual Sciences
I 216.368.4752
I www.case.edu/med/ophthalmology