Exercise Learning Objects Find Data Files GO Übergang_Übung_ETHZ/UZH_2008 Applied and Environmental Microbiology - extent and dimen Applied and Environmental Microbiology - extent and dimen Applied and Environmental Mocrobiology_Instructions to A Batch growth - interpretation of experimental data_ETHZ/UZ Batch_Übung_Auswertung_ETHZ/UZH_2008 Batch_Übung_ETHZ/UZH_2008 Blank (1997) Chemostat_Übung_Auswertung_ETHZ/UZH_2008 Chemostat_Kayseretal_Übung_ETHZ/UZH_2008 Continuous culture - interpretation of experimental data_ETHZ/UZH_2007 Egli et al. (1986) Egli et al.(1980) Egli et al., 1986 (100%) Excelberechnung Übungen Störung Excelberechnung Übungen Sterilisation Flyer BiotechLAB_080318 Ghent - ‚White’ (industrial) biotechnology Ghent - (Bio)process simulation Ghent - Process monitoring and data evaluation Kovarová et al. (1996) Lendenmann et al. (2000) Leták_biotechLAB Maurer, M., M., Kühleitner, B. Gasser, and D. Mattanov Versatile modeling and optimization of fed batch processes production of secreted heterologous proteins with Pichia pas Microbial Cell Factories. 5: 37. Monod (1949) Postup řešení BCNNb_001_CZ Rechenbeispiel Diauxie Rechenbeispiel Diauxie - Lösung s, x = f(D) spezifische D- und z-Werte verschiedener Mikroorganismen Standing et al. (1972) Transienten_Übung_Auswertung_ETHZ/UZH_2008 Transient_Lösungen Transient_ohne Lösungen Transition from batch to continuous culture_ETHZ/UZH_20 V:\Data-Monat\Data-Februar\hyp\Experiments_Data van Dijken et al. (1976) Varma and Palsson (1994) Vsádková kultivace_úvod Wanner and Egli (1990) = f(time) in Glucose-limitierter kontinuierlicher Kultur (E 1986) x,s XXX xxx (Varma and Palsson, 1994) xxx (Wanner and Egli, 1990) </div Supported by HELP | |1|2|3|4|5|6|7|8 References GO * log in to download the references Blank, L. M. 1997. Molecular and fermentation characterization of recombinant strains for metabolic engineering studies of Clostridium acetobutylicum. Master Thesis. Northwestern University, Evanston, IL, USA. Cereghino, J.L., and J.M. Cregg. 2000. Heterologous protein expression in the methylotrophic yeast Pichia pastoris. FEMS Microbiol. Rev. 24: 45-66. 483 kB pdf Curvers, S., P. Brixius, T. Klauser, J. Thoemmes, B.D. Weuster, R. Takors, and C. Wandrey. 2001. Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation. Biotechnol. Prog. 17: 495-502. 213 kB pdf d’Anjou, M.C., and A.J. Daugulis. 2001. A rational approach to improving productivity in recombinant Pichia pastoris fermentation. Biotechnol. Bioeng. 72: 1– 11. 214 kB pdf Desai, R.P., L.K. Nielsen, and E.T. Papoutsakis. 1999. Stoichiometric modeling of Clostridium acetobutylicum fermentations with non-linear constraints. J. Biotechnol. 71:191-205. 230 kB pdf Egli, T., Bosshard, C., and G. Hamer. 1986. Simultaneous utilization of methanol-glucose mixtures by Hansenula polymorpha in chemostat: Influence of dilution rate and mixture composition on utilization pattern. Biotechnol. Bioneng. 28: 1734-1741. 903 kB pdf Egli, T., J.P. van Dijken, M. Veenhuis, W. Harder, and A. Fiechter. 1980. Methanol Metabolism in Yeasts: Regulation of the Synthesis of Catabolic Enzymes. Arch. Microbiol. 124: 115-121. 1777 kB pdf Hans-Peter Meyer, 7. Juni 2007 1307 kB pdf Harris, L.M., L. Blank, R.P. Desai, N.E. Welker, and E.T. Papoutsakis. 2001. Fermentation characterization and flux analysis of recombinant strains of Clostridium acetobutylicum with an inactivated solR gene. J. Ind. Microbiol. Biotechnol. 27: 322-328. 167 kB pdf Ihssen, J., and T. Egli. 2004. Specific growth rate and not cell density controls the general stress response in Escherichia coli. Microbiol. 150: 1637 – 1648. 319 kB pdf Invitrogen. 2002. Pichia Fermentation Process Guidelines. Catalog No. K1710-01, Version B 053002, 1-11. http://www.invitrogen.com/content/sfs/manuals/pichiaferm_prot.pdf 162 kB pdf Kayser, A., J. Weber, V. Hecht, and U. Rinas. 2005. Metabolic flux analysis 226 kB of Escherichia coli in glucose-limited continuous culture. I. Growth-ratedependent metabolic efficiency at steady state. Microbiol. 151: 693 - 706. pdf Kovářová, K., A.J.B. Zehnder, and T. Egli. 1996. Temperature-Dependent Growth Kinetics of Escherichia coli ML 30 in Glucose-Limited Continuous Culture. J. Bacteriol. 178: 4530-4539. pdf 340 kB Kovarova-Kovar, K., and T. Egli. 1998. Growth Kinetics of Suspended Microbial cells: From Single-Substrate-Controlled Growth to Mixed-Substrate Kinetics. Microbiol. Mol. Biol. Rev. 62: 646–666. 2980 kB pdf Lendenmann, U., H. Senn, M. Snozzi, and T. Egli. 2000. Dynamics of Mixed Substrate Growth of Escherichia coli in Batch Culture: the Transition between Simultaneous and Sequential Utilisation of Carbon Substrates. Acta Univ. Carol. Environ. 14: 21-31. 2509 kB pdf Maurer, M., M., Kühleitner, B. Gasser, and D. Mattanovich. 2006. Versatile modeling adn optimization of fed batch processes for the production of secreted heterologous proteins with Pichia pastoris. Microbial Cell Factories. 5: 37. 323 kB pdf Minning, S., A. Serrano, P. Ferrer, C. Solá, R.D. Schmid, and F. Valero. 2001. Optimization of the high-level production of Rhizopus oryzae lipase in Pichia pastoris. J. Biotechnol. 86: 59–70. 196 kB pdf Monod, J. 1949.The growth of bacterial cultures. Annu. Rev. Microbiol. 3: 371-394. 1380 kB pdf Papoutsakis, E.T. 1984. Equations and Calculations for Fermentations of Butyric Acid Bacteria. Biotechnol. Bioeng. XXVI: 174-187. 1295 kB pdf Piñar, G., K. Kovářová, T. Egli, and J.L. Ramos. 1998. Influence of Carbon Source on Nitrate Removal by Nitrate tolerant Klebsiella oxytoca CECT 4460 in Batch and Chemostat Cultures. Appl. Env. Microbiol. 64: 2970 - 2976. 2073 kB pdf Standing, C.N., A.G. Frederickson, and H.M. Tschuchiya. 1972. Batch and continuous-culture transients for two substrate systems. Appl. Microbiol. 23: 354-359. 699 kB Tao, H., C. Bausch, C. Richmond, F.R. Blattner, and T. Conway. 1999. Functional Genomics: Expression Analysis of Escherichia coli. Growing on Minimal and Rich Media. J. Bacteriol. 181: 6425 - 6440. 1787 kB pdf van Dijken, J.P., Otto, R., and W. Harder. 1976. Growth of Hansenula polymorpha in a methanol-limited chemostat. Arch. Microbiol. 111: 137-144. 1375 kB pdf Varma, A., and B.O. Palsson. 1994. Stoichiometric Flux Balance Models Quantitatively Predict Growth and Metabolic By-Product Secretion in WildType Escherichia coli W3110. Appl. Environ. Microbiol. 60: 3724-3731. 1398 kB pdf von Meyenburg, K. 1971. Transport-Limited Growth Rates in a Mutant of Escherichia coli. J. Bacteriol. 107: 878-888. 1371 kB pdf Wanner, U., and T. Egli. 1990. Dynamics of microbial growth and cell composition in batch culture. FEMS Microbiol. Rev. 75: 19-44. 3208 kB pdf Zhang, W., J. Sinha, L. A. Smith, M. Inan, and M.M. Meagher. 2005. Maximization of production of secreted recombinant proteins in Pichia pastoris fed batch fermentation. Biotechnol. Prog. 21: 386-393. 195 kB pdf pdf RESULTS |