1 BSc (Hons) & Dip HE Mental Health & Learning Disabilities Nursing Numerical Assessment in Practice Workbook Student Name: Cohort group: The purpose of this workbook is to help you practice your numeracy skills associated with the safe administration of medication. These are required by the NMC for the achievement of Practice Learning Outcomes relating to competence in numeracy and calculation. This workbook may be used as supportive evidence of your preparation and therefore can be used in your discussions with your assessor. 2 Advice to Students Work your way through this workbook, working on the practice questions as you go. The answers are provided but try not to look at them before you have completed the exercises. Always show how you have worked out a particular question – this helps you identify any errors you might make and could help you and your assessor understand how you have arrived at the answer. Try wherever possible not to rely on using a calculator. By working things out on paper and using your own numeracy skills you are more likely to be able to spot where an answer seems to be wrong – for example, you know ‘in your head’ that the answer is likely to be 3 tablets and yet the calculator answer suggests 12. Safe Administration of Medicines - Guidance for Students The NMC Guide for Students of Nursing & Midwifery (April 2002) reminds you that: “During your studentship, you will come into close contact with patients or clients. This may be through observing care being given, through helping in providing care and, later, through full participation in providing care. At all times, you should work only within your level of understanding and competence, and always under the appropriate supervision of a registered nurse or midwife, or a health professional with a registered nurse or midwife providing mentorship.”(available from www.nmc-uk.org.) You must ensure that you follow the policies and guidelines of your placement trust. If you are uncertain of your role and responsibilities relating to any aspect of the safe administration of medication that you seek advice from a qualified member of nursing staff or your mentor. Further sources of support Whilst you are on practice you may also contact the designated pharmacist for your practice area for additional advice, guidance and information. 3 The Metric System Weight 1 kilogram 1 gram 1 milligram = = = 1000 grams 1000 milligrams 1000 micrograms 1 microgram = 1 nanogram = 1000 nanograms 1000 picograms Recognised abbreviations of these units are: kilogram = kg microgram = mcg gram = g nanogram = ng milligram = mg (Abbreviations for microgram and nanogram should not be used in prescribing.) Volume 1 litre = 1000 millilitres Recognised abbreviations of these units are: litre = L millilitre = ml Strength of a solution This can be expressed as: a) % weight versus volume = number of grams per 100mls e.g. sodium chloride 30% = 30g in 100mls b) Parts e.g. Adrenaline 1 in 1000 = 1g in 1000ml = 1mg in 1ml Adrenaline 1 in 10,000 = 1g in 10,000ml = 1mg in 10mls 4 Converting Larger Units to the Next Smaller Unit To convert a larger unit to a smaller unit you need to multiply by 1000. Example: Convert 5g to milligrams: Convert 0.25kg to grams: 5 x 1000 0.25 x 1000 = = 5000mg 250g Practice: Convert the following to micrograms 1. 0.5mg 2. 0.0625mg 3. 0.25 mg Convert the following into nanograms 4 0.25 mcg 5 0.0625 mcg 6 1.5mcg Converting smaller units to the next larger unit: To convert a smaller unit to the larger unit you divide by 1000. Example: Convert 6000g to kilograms : Convert 325mg to grams: 6000/ 1000 = 325/ 1000 = Practice: Convert the following into milligrams 7 300mcg 8 75mcg 9 187.5 mcg 6kg 0.325g 5 Dealing with Decimal Points 25 x 0.5 ____ 12.5 25 x 0.05 _____ 1.25 There is one number after the decimal point in the sum therefore one after the point in the answer. There are two numbers after the decimal point in the sum therefore two after the point in the answer. Practice 10. 2.5 x 100 = 11. 0.3 x1000 = 12. 7.5 x 30 13. 36 60 = 14. 125 550 = (calculate to 2 decimal places) = 15. 5.5 50 = 16. 250 1000 = 6 Fractions To simplify fractions divide the top number into the bottom number, which divides into both of these exactly. This number is called a common factor. e.g. 24 = 2 36 3 (both numbers have been divided by 12, which is a common factor used in this fraction.) This could also have been completed in several steps: 24 36 = 12 18 (common factor is 2) = 4 6 (common factor is 3) = 2 3 (common factor 2) Then 12 18 Then 4 6 Converting fractions to decimals In order to convert a fraction to a decimal, you need to divide the top number by the bottom number. e.g. 1 = 2 2 (divide the top number by the bottom one) 0.5 1.0 = 0.5 Practice 17. 3 9 21. 3 = 4 = 18. 22. 6 = 2 1 100 19. = 25 = 75 20. 7 = 8 7 Fluid Requirements First 10kg = 100ml/kg Second 10kg = 50ml/kg Subsequent = 20ml/kg Practice: Using the above formula calculate the daily fluid requirements 23. 6.2kg 24. 3.8kg 25. 29kg Unit conversion 26. 4000 micrograms = 2 litres = mg ml 6mg = 0.24 micrograms = micrograms nanograms 75 mg = grams 187.5 micrograms = mg 650 ml = litres 0.25 micrograms = nanograms 8 Oral Liquids Triclofos is a sedative produced in concentration of 500mg/5mls. Calculate the volumes for the following doses: 27. Dose Prescribed (mg) 250 350 65 150 750 Volume Required (ml) Ranitidine comes in a concentration of 150mg in 10mls; calculate the volumes needed for the following doses: 28. Dose Prescribed (mg) 25 16 35 65 150 Volume Required (ml) Drug Dosages for Injection Volume Required = Dose prescribed Dose you have available x volume of stock solution e.g. A patient is prescribed cortisone 40 mg. The ampoules contain 50 mg in 2mls. Calculate the volume required. Using the formula 40 mg x 2ml 50mg = 40 x 2 9 50 Answer = 8 5 1 = 1.6 mls Practice 29. If 50 mg of a drug is contained in 10ml of solution, how much must be given to give 25mg? 30. Prescribed: Erythromycin 270 mg Available: 300mg in 10 mls 31 Morphine 9 mg is required and the stock solution is 15mg in 1 ml. How much is required? 32. The ampoule reads 500micrograms in 5 mls of solution. How much solution is needed to give 10 micrograms? More Practice Questions: Q1. Mellisa Wayfield is due to be discharged from the unit where you are working. She has been prescribed Paroxetine 40mgs daily for her feelings of panic. These are dispensed as 20mg tablets and she will need enough tablets for 4 weeks. (a) How many 20mg tablets will need to be dispensed? a) Paroxetine is available in packs of 15 tablets per pack. How many whole packs should be in her discharge medication? 10 Q2. David, who has a bi-polar disorder, is going through a period of significant depression and there is some concern that his fluid balance is not being well maintained (see chart below for details). a) Complete this table to give the daily total for both intake and output FLUID INTAKE (millilitres) TIME 3rd March 4th March 5th March 08:00 09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 300 300 250 DAY TOTALS 20:00 21:00 22:00 23:00 00:00 01:00 02:00 03:00 04:00 05:00 06:00 07:00 FLUID OUTPUT (millilitres) 6th March 3rd March 4th March 5th March. 6th March 250 280 280 230 250 250 125 135 225 300 135 133 240 300 250 175 220 370 270 140 152 200 230 270 250 525 225 250 300 450 330 125 100 380 150 350 320 400 300 NIGHT TOTALS 24 HOUR TOTALS b) What is David’s average daily fluid intake over these 4 days? 345 11 c) What is David’s average daily fluid output over these 4 days? David is thought to be developing a chest infection, so 400mg of an antibiotic is prescribed, to be administered 6-hourly. The antibiotic comes in a suspension of 125mg in 5 ml. d) How many ml will be needed for all doses over a 24-hour period? David is being treated with Lithium Citrate in order to help him control his mood. Currently he is being given that in liquid form and it comes in a suspension which contains 520mg/5mls. He is prescribed 2.6 g daily to be given in 2 evenly divided doses e) How many millilitres should be given in each dose? Now David has recovered a little and it has been decided to return him to the tablet form of Lithium Carbonate. The pharmacy is preparing a bottle of tablets for David to take away with him for a weekend break. The tablets come in 200 mg. David is prescribed 0.6 grams twice daily. f) If David is going away for 3 days how many tablets does the pharmacist need to dispense for his trip? 12 g) David actually returned home early after 2 days. How many tablets should be left in his drug bottle? Q3. Susan has regular epileptic seizures but these are reasonably controlled through the use of medication. Currently she is prescribed Phenytoin in a suspension which contains 15mg/2.5ml. The initial dose is worked out according to body weight (3.5mg per kg daily). a) If Susan is 86kg what would her initial daily dose be (to the nearest 10mg)? Because Susan’s epilepsy is now generally well-controlled she is actually prescribed 255 mg Phenytoin a day to be given in 2 equal doses. b) How many millilitres of suspension should be given in each dose? Susan then has a bout of flu and this interferes with her ability to control her seizures. She enters a state of Status Epilepticus and requires Diazepam rectal solution to be administered. She is prescribed 30 mg as a one off dose to be repeated after 12 hours if necessary. Rectal tubes contain 4mg per ml and come in 2.5 ml tubes. c) How many tubes are required for that first treatment? Q.4 Zuclopenthixol Acetate (Clopixol Acuphase) is administered by injection for the treatment and management of acute psychosis, mania or exacerbations of chronic psychosis. Ben Yuhuru has exhibited increasingly impulsive and dangerous behaviour over the past 24 hour period, placing others at 13 considerable risk. He is prescribed Clopixol Acuphase 150mgs by deep muscular injection. a) Clopixol Acuphase is available in ampoules of 50mgs in 1ml liquid suspension. How many ampoules will need to be drawn up for the correct dose to be given? b) He is prescribed a further injection after 2 days of the same dose of Clopixol Acuphase after the first injection was given and another injection 1 day later of a reduced dose of 100mg. The maximum accumulative dose should not exceed 400mgs over the course of a few days, has this been exceeded? c) How many ampoules have been used in total? Q5. Stephen Wilson, a service user has become very distressed and aggressive on the unit. He is at risk of harming himself and of harming other people. It has been decided by the team that for his own safety and for the safety of others he will need to have an injection of lorazepam. The medicine card indicates that a 2mg dose should be given. Lorazepam is available as 4mg/ml solution in 1ml ampoules, and it should be diluted with an equal volume of water for injection. a) What volume of lorazepam injection is needed? b) Once this is diluted with an equal amount of water what will be the total volume in the syringe? 14 Answers to Practice Questions 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 500 micrograms 62.5 micrograms 250 micrograms 250 nanograms 62.5 nanograms 1500 nanograms 0.3 mgs 0.075 mgs 0.1875 mgs 250 300 225 0.6 0.23 0.11 0.25 0.333 3 0.333 0.875 0.75 0.01 620 mls 380 mls 1680 mls 26. 4000 micrograms = 4 mg 6mg = 6000 micrograms 2 litres = 2000ml 0.24 micrograms = 240 nanograms 75 mg = 0.075grams 187.5 micrograms = 0.1875 mg 650 ml = 0.65 litres 0.25 micrograms = 250 nanograms 15 27. Dose Prescribed (mg) 250 350 65 150 750 Volume Required (ml) 2.5 3.5 0.65 1.5 7.5 28. Dose Prescribed (mg) 25 16 35 65 150 29 30 31 32 Volume Required (ml) 1.66 1.066 2.33 4.33 10 5 mls 9 mls 0.6 mls 0.1 mls Answers to More Practice Questions Q1. Mellisa Wayfield is due to be discharged from the unit where you are working. She has been prescribed Paroxetine 40mgs daily for her feelings of panic. These are dispensed as 20mg tablets and she will need enough tablets for 4 weeks. (a) How many 20mg tablets will need to be dispensed? 56 tablets b) Paroxetine is available in packs of 15 tablets per pack. How many whole packs should be in her discharge medication? 4 whole packs 16 2. a) Complete this table to give the daily total for both intake and output FLUID INTAKE (millilitres) TIME 3rd March 4th March 5th March 08:00 09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 300 300 250 DAY TOTALS 20:00 21:00 22:00 23:00 00:00 01:00 02:00 03:00 04:00 05:00 06:00 07:00 FLUID OUTPUT (millilitres) 6th March 3rd March 4th March 5th March. 6th March 250 280 280 230 250 250 125 135 225 300 135 133 240 270 140 152 200 300 250 175 220 370 230 270 250 525 225 250 300 1645 925 920 1215 950 450 695 330 700 125 100 760 380 150 350 320 400 300 NIGHT TOTALS 0 average100 125 over these 150 What is David’s daily fluid intake 4 days? 850 630 670 725 24 HOUR TOTALS 1270ml 1325 1370 1485 1645 1025 1045 1365 1800 What is David’s average daily fluid output over these 4 days 1495ml b) What is David’s average daily fluid intake over these 4 days? 1270 ml c) What is David’s average daily fluid output over these 4 days? 1495 ml 345 17 David is thought to be developing a chest infection, so 400mg of an antibiotic is prescribed, to be administered 6-hourly. The antibiotic comes in a suspension of 125mg in 5 ml. How many ml will be needed for all doses over a 24-hour period? 64ml David is being treated with Lithium Citrate in order to help him control his mood. Currently he is being given that in liquid form and it comes in a suspension which contains 520mg/5mls. He is prescribed 2.6 g daily to be given in 2 evenly divided doses How many millilitres should be given in each dose. 12.5ml Now David has recovered a little and it has been decided to return him to the tablet form of Lithium Carbonate. The pharmacy is preparing a bottle of tablets for David to take away with her for a weekend break. The tablets come in 200 mg. David is prescribed 0.6 grams twice daily. If David is going away for 3 days how many tablets does the pharmacist need to dispense for his trip? 18 tablets David actually returned home early after 2 days. How many tablets should be left in his drug bottle? 6 tablets Q3. Susan has regular epileptic seizures but these are reasonably controlled through the use of medication. Currently she is prescribed Phenytoin in a suspension which contains 15mg/2.5ml. The initial dose is worked out according to body weight (3.5mg per kg daily). If Susan is 86kg what would her initial daily dose be (to the nearest 10mg)? 300mg Because Susan’s epilepsy is now generally well-controlled she is actually prescribed 255 mg Phenytoin a day to be given in 2 equal doses. How many millilitres of suspension should be given in each dose? 21.25ml Susan then has a bout of flu and this interferes with her ability to control her seizures. She enters a state of Status Epilepticus and requires Diazepam rectal solution to be administered. She is prescribed 30 mg as a one off dose to be repeated after 12 hours if necessary. Rectal tubes contain 4mg per ml and come in 2.5 ml tubes. How many tubes are required for that first treatment? 3 tubes Q4. Zuclopenthixol Acetate (Clopixol Acuphase) is administered by injection for the treatment and management of acute psychosis, mania or exacerbations of 18 chronic psychosis. Ben Yuhuru has exhibited increasingly impulsive and dangerous behaviour over the past 24 hour period, placing others at considerable risk. He is prescribed Clopixol Acuphase 150mgs by deep muscular injection. (a) Clopixol Acuphase is available in ampoules of 50mgs in 1ml liquid suspension. How many ampoules will need to be drawn up for the correct dose to be given? 3 ampoules (b) He is prescribed a further injection 2 days of the same dose of Clopixol Acuphase after the first injection was given and another injection 1 day later of a reduced dose of 100mg. The maximum accumulative dose should not exceed 400mgs over the course of a few days, has this been exceeded? No (c) How many ampoules have been used in total? 8 ampoules Q5. Stephen Wilson, a service user, has become very distressed and aggressive on the unit. He is at risk of harming himself and of harming other people. It has been decided by the team that for his own safety and for the safety of others he will need to have an injection of lorazepam. The medicine card indicates that a 2mg dose should be given. Lorazepam is available as 4mg/ml solution in 1ml ampoules, and it should be diluted with an equal volume of water for injection. c) What volume of lorazepam injection is needed? 0.5ml lorazepam is needed d) Once this is diluted with an equal amount of water what will be the total volume in the syringe? 0.5ml lorazepam + an equal volume of water will give a total of 1ml in the syringe