Banning AP PROF ADRIAN P BANNING MD, FRCP, FESC Title Consultant Cardiologist Department of Cardiology John Radcliffe Hospital Headington Way Oxford. UK OX3 9DU Tel 01865-741166 (hospital switch) Tel 01865-228934 (Secretary) FAX 01865-220252 E mail address adrian.banning@orh.nhs.UK Date of Birth: Nationality: GMC 11th June 1963 British 3247004 Qualifications: MB BS (St Georges, London UK MD (University of London) FESC FRCP Good clinical practice course attended June Feb Aug June 1987 1997 2001 2003 7 May 2008 Current Post The John Radcliffe is a University Hospital and I have extensive experience in under-graduate teaching and teaching Specialist Registrars. I am a Consultant Cardiologist (started post August 1999) and I work as both an interventional cardiologist and participate in general cardiology. I qualified from London (MB BS) and subsequently attained an MD in 1997 studying at the University Hospital of Wales. Whilst in Oxford my research has focused on applications of drug eluting stents, percutaneous coronary intervention in acute coronary syndromes and mechanisms of myocardial injury during PCI. I have on call responsibilities for the full range of regional centre cardiology and I am responsible for all the emergency procedures in the catheter lab two days in five. I have published over 190 peer reviewed scientific papers and was Assistant Editor to the journal Heart for 6yrs. I act as referee for Circulation, Lancet, Nature Cardiovascular Medicine etc Invasive Cardiology I supervise and/or perform coronary intervention 4 sessions per week in two cardiac catheter laboratories and perform>350 coronary intervention procedures per annum including mutivessel angioplasty and primary angioplasty for AMI. I perform TAVI and balloon mitral valvotomy. I have attended a number of live intervention courses both in the UK and internationally and have trained a number of doctors that have subsequently become independent operators. I have introduced intravascular ultrasound to our laboratory and I am the lead interventionalist in our centre for the following international studies REACT study - UK based study of management of failed thrombolysis In the top 5 recruiting centers TAXUS 2 study-– sponsored by Boston Scientific (involves IVUS and QCA follow up) Recruited 43 patients in 3 months. 2nd largest recruitment center in the world DISCOVER 2- sponsored by Guidant Recruited 19 patients. 2nd largest recruitment center in the UK ENDEAVOUR 2-sponsored by Medtronic IVUS substudy centre TAXUS 6- sponsored by Boston Scientific (involves IVUS and QCA follow up) Recruited 29 patients. Joint 3rd largest recruitment centre in the Europe/world SYNTAX- sponsored by Boston Scientific UK PI for intervention Recruited 42 pts Best recruitment in the UK and 4th in the world HORIZONS sponsored by Cardiovascular Research Foundation UK PI for this primary PCI study E SELECT sponsored by Cordis UK PI and steering group member Within the top 5 UK recruiters 1 Banning AP Elected BCIS council member 2002-6 Atherothrombosis and Hypertension Clinical Study Group S Central representative for National Institute for Health Research Clinical Research Network Invited Faculty Member Advanced Angioplasty Meeting (ACI) London 2000 to 2011 Live case operator 2007, 2008, 2010 Euro PCR 2004, to 2010 Live case operator 2006 TCT 2005,2006, 2007, 2008,2009 Live case operator 2008 Oxford live site principal coordinator 2010 Non-invasive cardiology I am accredited with the British Society of Echocardiography to Adult proficiency level. I have 10 years experience in transoesophageal echocardiography and I have a research interest in the diagnosis and management of thoracic dissection and intramural aortic haematoma I have also contributed to a number of the ongoing clinical research projects being carried out in the department including studies on temporary pacing and myocardial stunning. I am the co-principal investigator on the Jarvik Artifical Heart programme in Oxford. This is an LVAD designed for permanent implantation in patients not suitable for cardiac transplantation. I am involved in the OXVASC study which is a community based study of patients presenting with AMI, ACS TIA or stroke. I am also on the steering committee of the GALA study which is a randomised comparison of local vs general anaesthesia for carotid surgery. Bibliography (5 selected) Kelion A, , Webb T, Gardner M, Ormerod OJ, Banning AP "Preconditioning" against left ventricular dysfunction follows exercise induced ischaemia in multivessel coronary disease. J Am Coll Cardiology 2001;37:705-710 A Randomized Study to Assess the Benefit of Paclitaxel-Eluting Stents for Coronary Revascularization using. Two Different Release Kinetics in De Novo Coronary Lesions (TAXUS 2) Colombo A, Drzewiecki J, Banning AP, Hauptmann K, Grube E, Dudek D, Fort S, Schiele S, Silber S, Zmudka Z, Guagliumi G, Russell ME Circulation. 2003;108: 788-94. Selvanayagam JB; Porto I; Channon K;. Petersen SE. Francis JM; Neubauer S; Banning AP Troponin Elevation Following Percutaneous Coronary Intervention Directly Represents the Extent of Irreversible myocardial injury : Insights from Cardiovascular Magnetic Resonance Imaging Circulation 2005 111:1027-32 Porto I, Selvanayagam SB, Van Gaal WJ, Prati F, Cheng A, Channon KM Neubauer S, Banning AP Plaque volume and the occurrence and location of peri-procedural myocardial necrosis following PCI: Insights from delayed enhancement MRI, TIMI myocardial perfusion grade analysis and Intravascular Ultrasound Circulation 2006 ; 114:662-9 Banning AP, Westaby S, Morice MC, Kappetein AP, Mohr FW, Berti S, Glauber M, Kellett MA, Kramer RS Leadley K, Dawkins KD, Serruys PW Comparison of Cardiac Surgery and Paclitaxel-Eluting Stents in Nondiabetic and Diabetic Patients with Left Main and or 3 vessel coronary artery disease J Am Coll Cardiol. 2010; 55:1067-1075 2