LOYOLA UNIVERSITY CHICAGO INTRAMURAL GRANT APPLICATION GUIDELINES Research Funding Committee (RFC) Chair: Dr. Alan Wolfe Committee Support: Carol Wojtulewicz Office of Research Services for the Health Sciences (ORS-HS) Bldg. 120 - Rm. 400 Ext. 6-8434 Revised & Approved by the RFC: June 2007 Revised & Approved by the RFC: December, 2009 AW/clw G:\Research Services\Research Funding Committee\2009Guidelines-Application\RFCIntGrntApGdlns-Final12-2009.doc 1 POLICIES and GUIDELINES RESEARCH FUNDING COMMITTEE (RFC) PROCEDURES for INTRAMURAL APPLICATIONS MISSION STATEMENT: Intramural Research Funds are used to meet both emerging opportunities and urgent needs. These include supporting young/new faculty member(s) in a period of pilot or preliminary investigation that will eventuate in subsequent funding by an external agency, supporting needs of established research programs for which funding may have lapsed temporarily, and allowing the exploration of novel research ideas that may lead to new research directions. Both basic science and clinically based research proposals will be considered. These proposals should be hypothesis-driven and consistent with the rigor required for extramural review. New or less experienced investigators are highly encouraged to obtain input from colleagues who have been successful in obtaining extramural funding as they can often provide valuable input regarding preparation of the RFC proposal. Poorly prepared applications may be returned to the applicant for revision before review by the RFC. CONTACTS Alan Wolfe, Ph.D. Chair, RFC <awolfe@lumc.edu> Carol Wojtulewicz, Support Person, RFC <cwojtul@lumc.edu> Richard H. Kennedy, PhD, VP for Health Sciences Research <rkennedy@lumc.edu> MEETING DATES/SUBMISSION DATES The RFC meets quarterly. The dates are posted at: http://www.meddean.luc.edu/res_serv/ors/committee.htm Specific questions should be directed to the Chair, Dr. Alan Wolfe, PhD (awolfe@lumc.edu). AWARD CATEGORY NEW INVESTIGATOR AWARD – provides support for new faculty, who have not been awarded start-up funds, in a period of pilot or preliminary investigation. PILOT AWARD - provides support for any faculty member in a period of pilot or preliminary investigation. BRIDGE AWARD – supports the needs of established research programs for which funding has temporarily lapsed. TRANSLATIONAL AWARD – provides support for new collaborative research projects proposed by a team including clinicians and basic scientists. Although clinical research activity is not a strict requirement for this award, the future clinical impact of the research must be well described in the proposal. 1 GENERAL INFORMATION - Applies to all four award categories. The guidelines and application can be found at: http://www.meddean.luc.edu/res_serv/ors/committee.htm Eligibility o Only full-time Loyola faculty may apply as principal investigator (P.I.). New faculty are not eligible until start-up monies have been expended. o VA based, Loyola faculty are eligible if they currently have or have had external research funding administered by the University, or have significant teaching, administrative or clinical commitments to the Stritch School of Medicine (SSOM). o Research Fellows, Research Associates and Research Assistant/Associate/ Full Professors are not eligible. Individuals who are not full-time faculty can be listed as co-P.I. in collaboration with a full-time faculty person who is listed as P.I. Submission Format o Submit the following to Carol, electronically: 1) the abstract and 2) a pdf of the proposal. Also submit 3 hard copies. o Grant Routing Form - go to the Portal, log in and select the Research Channel, then select New Routing form. The process is self-explanatory. o Signature(s) required for safety clearances MUST be obtained. NOTE: If and/or when monies are awarded, Grant Accounting will NOT issue an account number unless ALL safety clearances have been met, i.e., IACUC, IRB, IBC and RCO. Complete the Intramural Grant Application (all forms are part of the application). o Table of Contents Page o Signature Page o Cover Letter Form o Budget Justification o Biographical sketch of P.I. and Co. P.I.(s) o Abstract (email to Carol Wojtulewicz <cwojtul@lumc>) o Other Support (Requires signature) o Consultants and other support letters. o Resources and environment (Use NIH format). o Reviews/Pink Sheets (required for bridge funding applications). o Progress Reports from other funding sources, when appropriate. o Response to critiques/pink sheets (for bridge funding applications). o Proposal (Specific Aims, Significance, Preliminary Data if available, Experimental Designs and Methods). NOTE: 21 Page Limitation. o Literature cited. o Attach P.I.’s last 10 years of funding history, including intramural sources. o Safety Committee Approvals (IACUC, IBC, IRB, RCC) IACUC (Animal Care) IBC (Biosafety) IRB (Human Subjects) RCO (Radiation Control) SAFETY COMMITTEES Dr. J. Fareed <jfareed@lumc.edu> (x 65997) Elaine Fluder, MSN <efluder@lumc.edu> (x66198) Dr. Ken Micetich <kmiceti@lumc.edu> (x64608) Dr. Kevin Corrigan <kcorrig@lumc.edu> (x69260) 2 Deadlines o Projects that have NOT already been reviewed externally require submission 6 weeks prior to the RFC meeting date to allow for contact with suggested external reviewer and time for the reviewer to write and submit critique. o Projects that have already been reviewed externally are due 4 weeks prior to the RFC meeting date to allow for RFC review and written comments to be submitted. External Review Procedure The ORS-HS will solicit an external review for any project that has not already been externally reviewed and will provide a modest honorarium to the reviewer. The P.I. will submit the name, title, email address and institution of 3-4 potential outside reviewers with whom they have NOT had prior collaboration. The external reviewer will remain anonymous to the P.I. Limitations o Funding of more than one RFC proposal by the same P.I. in a 12 month period will not be considered. o With the exception of VA funding, future extramural support directly related to previous RFC funding must be administered through Loyola University Chicago/SSOM. o RFC awarded Pilot, New Investigator, and Translational Grants cannot be used to support graduate student stipends and health insurance. o P.I.s supported by the RFC must notify the ORS-HS when external funding is received for work similar to that being supported by the RFC. o Remaining or duplicate monies, where applicable, will be returned to the RFC. o A 1-Year No-Cost Extension must be requested with appropriate justification, in writing (email), to Drs. Kennedy and Wolfe for approval. Nocost extensions are limited to one year. o The RFC does not support travel expenses or publication costs. o Equipment/computer support is generally discouraged, but may be considered on an individual basis. o Graduate student stipends and faculty salaries are not supported. o Post Doctoral fellows can be supported at a technician salary level. o Supplies should not exceed $25,000/12 months (includes supplies and animals). o Proposal - 21 Page limitation Progress Report Progress Report must be submitted to the RFC Chair no later than two months after the original funding end-date. 3 SPECIFIC AWARD INFORMATION New Investigator Award Projects that have not already been reviewed externally need to be submitted 6 weeks prior to the meeting date. New faculty members are not eligible, until they have expended their start-up monies. o Eligibility - See General Information above o Budget - Total budget request cannot exceed $40,000 (technician or post-doctoral fellow salary not to exceed $30,000, including fringe benefits. Supplies should not exceed $25,000/12 months (includes supplies and animals). o RFC awarded New Investigator Grants cannot be used to support graduate student stipends and health insurance. o Second Review - Applications for a second year of funding require a new Routing Form and should clearly explain in the Cover Letter why continued intramural funding is required. The RFC will make funding recommendations based on the application’s priority compared with other pending proposals and the likelihood of eventual extramural support. Pilot Award Projects that have not already been reviewed externally need to be submitted 6 weeks prior to the meeting date. o Eligibility - See General Information above. o Budget – Total budget request cannot exceed $25,000. The budget is generally limited to supplies only, but technicians or post-doctoral fellows may be supported with adequate justification. o RFC awarded Pilot Grants cannot be used to support graduate student stipends and health insurance. o Second Review - Applications for a second year of funding require a new Routing Form and should clearly explain in the Cover Letter why continued intramural funding is required. The RFC will make funding recommendations based on the application’s priority compared with other pending proposals and the likelihood of eventual extramural support. Bridge Awards Projects that have been externally reviewed are due 4 weeks prior to the meeting date and should include the most recent external reviews. o Eligibility - See General Information above. o The proposal for continuing external support (i.e., competing renewal) must have been submitted and reviewed. o Include the critique(s) provided by the external agency and a detailed response to the critique. o Include a complete listing of extramural and intramural research support available to the principal investigator. o Budget - Total budget request cannot exceed $40,000 (technician or post-doctoral salary not to exceed $30,000, including fringe benefits). o RFC awarded Bridge Grants can be used to support graduate student stipends and health insurance with approval of Drs. Wolfe and Kennedy per Graduate School, 4 LUMC policy dated August 2007. Translational Awards Translational Awards provide pilot support for new collaborative research projects proposed by a team including clinical and basic scientists. Although clinical research activity is not a strict requirement for this award, the future clinical impact of the research must be well described in the proposal. o Eligibility - See General Information above. o Projects that have not already been reviewed externally need to be submitted 6 weeks prior to the meeting date. Projects that have been externally reviewed are due 4 weeks prior to the meeting date and should include the most recent external reviews. o Budget - These grants, which require collaboration between clinicians and basic scientists, cannot exceed $30,000; in some cases, technician or coordinator salaries will be supported. o RFC awarded Translational Grants cannot be used to support graduate student stipends and health insurance. o Second Review - Applications for a second year of funding require a new Routing Form and should clearly explain in the Cover Letter why continued intramural funding is required. The RFC will make funding recommendations based on the application’s priority compared with other pending proposals and the likelihood of eventual extramural support. AW/clw G:\Research Services\Research Funding Committee\2009Guidelines-Application\RFCIntGrntApGdlns-Final12-2009.doc 5