Sudden Arrhythmic Death Syndrome Dr. Simon Modi – Consultant Cardiologist/Electrophysiologist, Dr. Robert Cooper – Cardiology Specialist Registrar, Suzanne Kelly – Heart Rhythm Specialist Nurse Liverpool Heart and Chest Hospital Brugada syndrome: Brugada syndrome is a purely electrical disorder of the heart. It does not show up on heart scans as the heart size and structure is often normal. An ECG is the only way this abnormality can be can be picked up. Sometimes repeated ECGs at different times, after large meals or after an injection of a special heart rhythm medicine are required to diagnose the condition. Under certain circumstances it can cause a fatal disturbance of the heart’s rhythm. Fever, certain medications and sleep are all potential triggers for rhythm disturbance in the Brugada syndrome. Many Brugada syndromes are inherited and family screening is important. People with Brugada syndrome generally feel well but may have noted prior dizzy spells or faints. The Brugada syndrome almost always affects young men. ECG showing the Brugada syndrome Left = normal ECG. Right = Brugada ECG change