George Fu Gao ( 高福 ) ， DVM, DPhil (Oxon)
Director-General and Professor
Institute of Microbiology
Chinese Academy of Sciences
(IMCAS)
Beijing 100080, P. R. China
Research Interests:
George’s research focuses primarily on the Molecular Immunology and Molecular
Virology, esp. structural biology and protein chemistry related field. Research on
T-cell molecular recognition and molecular mechanism of virus entry, including avian influenza , SARS-CoV , HBV and HIV, are his expertise.
Education:
1979-1983 Shanxi Agricultural University, China B.Sc, DVM
1983-1986 Beijing Agricultural University, China M.Sc
1991-1994 Oxford University, United Kingdom, DPhil (awarded in 1995)
(Molecular Virology)
Career:
1987-1991
1995-1998
Lecturer (Virology), College of Vet. Med., Beijing
Agricultural University (BAU), P.R. China
Welcome Trust/MRC Postdoctoral Research Assistant
(RS1A), Nuffield Dept. of Clinical Medicine, Institute of
Molecular Medicine, Oxford University. (Three months of
Academic visit as a postdoc fellow at Dept. of Clinical
Neurosciences, The University of Calgary, Canada, in the end of 1994, before taking up the Oxford postdoc position).
1998(Oct)-1999 (Feb) Research Associate (Band 3), MRC Human Immunology
Unit, Institute of Molecular Medicine, University of Oxford
1999 (Feb)-2001 Welcome Trust (UK) International Research Fellow, Howard
2001-2004
Hughes Medical Institute, Children's Hospital; Dept. of
Biological Chemistry and Molecular Pharmacology, Harvard
Medical School; and Dept. of Molecular and Cellular
Biology, Harvard University
Lecturer*, Nuffield Dept. of Clinical Medicine, Oxford
University
2004- Professor, Director-General of IMCAS

1988, Young Scientist Award—China Association for Science and Technology
1991, Sino-British Friendship Scholarship Scheme (SBFSS) Fellowship of the British
Council
1998, UK Wellcome Trust International Travelling Fellowship
2002, National Natural Science Foundation of China (NSFC) “Oversea Outstanding
Young Scientist “(B Type).
2003, Ministry of Education, P. R. China , “Chun Hui Project”
2005, Chief Scientist, MOST 973 Project
2005, National Natural Science Foundation of China (NSFC) (A Type)
1. Visiting Professor, China Agriculture University
2. Guest Professor, Wu Han University
3. Vice-president, Asian Coneortium for the Conservation and Sustainable Use of
Microbial Resources (ACM)
5. Editorial board,
《
Pharmaceutical Biotechnology
》
6. Executive vice-President, Biotechnology Society of China
7. Executive Councilor, China Preventive Medicine Association.
8. Vice-president, Academic committee Department of Infectious Disease, Capital
University of Medical Sciences.
9. Editorial board,, JGV （ Journal of General Virology 》
10.
Editorial board, Zoonoses and Public Health
1. Chinese Academy of Sciences (CAS) “Hundred-talent Project”
2. Chinese Academy of Sciences (CAS) President Foundation
3. The National Natural Sciences Foundation of China (NSFC)
4. The Key Project of the Knowledge Innovation Program of Chinese Academy of
Sciences (CAS).
5. National Program on Key Basic Research Projects (973) (Chief scientist)
6.
National High-tech R&D Program (863 Program)
7. National Key Technologies R&D Program
1. CD8 as an inhibitor of the cellular immune system, PCT/GB 98/03235 (1997) (with
Gerth, U.C., Sewell, A.K., Bell , J.I. and Jakobsen, B.K.).
2. Soluble T cell receptor, PCT/GB 9810759.2 (1998) (with Willcox B.E., Boulter,
J.M., Bell , J.I and Jakobsen, B.K.).
3. Heat-shock protein gp96 and HBV peptide complex used for HBV-induced hepatic carcinoma, PCT/CN01/00295 (2001) (with Meng, S.-D. and Tien, P.).
4. Potent peptide inhibitors for SARS coronavirus, PCT/CN03/00457
（
2003
）
(with
Tien, P., Zhu, J., Xiao, G. & Zheng, C.).

Publication List :
1.
Chen, C, Tang, J, Dong, W, Wang, C, Feng, Y, Wang, J, Zheng, F, Pan, X, Liu,
D, Li, M, Song, Y, Zhu, X, Sun, H, Feng, T, Guo, Z, Ju, A, Ge, J, Dong, Y,
Sun, W, Jiang, Y, Wang, J, Yan, J, Yang, HM, Wang, X * , Gao*, G.F
., Yang,
R * , Wang, J * , Yu, J * , 2007, A Glimpse of Streptococcal Toxic Shock
Syndrome from Comparative Genomics of S. suis 2 Chinese Isolates, PLoS
ONE , 2: e315
2.
Cole, DK, Rizhallah, PJ, Boulter, JM, Sami, M, Vuidepot, AL, Glick, M, Gao,
F , Bell, JI, Jakobsen*, BK, Gao*, G.F
.
, 2007 , Computational design and crystal structure of an enhanced affinity mutant human CD8

coreceptor,
PROTEINS: Structure, Function, and Bioinformatics, 67 (1), 65-74 (with front cover illustration)
3.
Chu, F, Lou, Z, Chen, YW, Liu, Y, Zong, L, Gao, B, Khan, AH, Bell, JI, Rao,
Z and Gao*, G.F
.
, 2007, First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape , The Journal of
Immunology, 178 (2), 2007, 944-952.
4.
Chang, S, Zhang, J, Liao, X, Zhu, X, Wang, D, Zhu, J, Feng, T, Zhu, B, Gao,
G.F
, Wang, J, Yang, HM, Yu, J* and Wang, J*, 2007, Influenza Virus Database
(IVDB): an integrated information resource and analysis platform for influenza virus research, Nucleic Acids Research , 35 (Database issue),
D376-80.
5.
Zhang, JY, Zhang, Z, Wang, X, Fu, JL, Yao, J, Jiao, Y, Chen, L, Zhang, H,
Wei, J, Jin, L, Shi, M, Gao, G.F
, Wu, H, Wang*, FS, 2007, PD-1 upregulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors, but not in long-term non-progressors, Blood (In press)
6.
Cole, DK, Pumphrey, NJ, Boulter, JM, Sami, M, Bell, JI, Gostick, E, Price,
DA, Gao, G.F
, Sewell, AK, Jakobsen, BK, 2007, Human T-cell receptor binding affinity is governed by major histocompatibility complex class restriction, The Journal of Immunology (In press)
7.
Fan, Z, Zhuo, Y, Tan, X, Zhou, Z, Yuan, J, Qiang, B, Yan, J, Peng, X, Gao*,
G.F
, 2006, SARS-CoV nucleocapsid protein binds to hUbc9, a ubiquitin conjugating enzyme of the sumoylation system, Journal Medical Virology, 78
(11), 1365–1373
8.
Lou, Z, Xu, Y, Xiang, K, Su, N, Qin, L, Li, X, Gao, G.F
, Bartlam, M and
Rao*, Z, 2006, Crystal structures of Nipah and Hendra virus fusion core proteins, FEBS Journal, 273 (19), 4538–4547
9.
Liu, Y, Xu, Y, Lou, Z, Zhu, J, Hu, X, Gao*, G.F
, Qiu*, BS, Rao*, Z, Tien, P*,
2006, Structural characterization of Mumps virus fusion protein core,
Biochemical and Biophysical Research Communications, 348 (3), 916–922

10.
Zhou, M, Xu, D, Li, X, Li, H, Shan, M, Tang, JR, Wang, M, Wang, FS, Zhu,
X, Tao, H, He, W, Tien, P*, and Gao*, G.F, 2006, Screening and Identification of Severe Acute Respiratory Syndrome-Associated Coronavirus-Specific CTL
Epitopes, The Journal of Immunology , 177 (4), 2138-2145
11.
Kannan, S, Audet, A, Knittel, J, Mullegama, S, Gao, G.F
and Wu, M*, 2006,
Src kinase Lyn is crucial for Pseudomonas aeruginosa internalization into lung cells. European Journal of Immunology , 36 (7), 1739-1752
12.
Zhang, Y, Zan, Y, Shan, M, Liu, C, Shi, M, Li, W, Zhang, Z, Liu, N, Wang, F,
Zhong, W, Liao, F, Gao*, G.F
, Tien, P*, 2006, Effects of heat shock protein gp96 on human dendritic cell maturation and CTL expansion, Biochemical and Biophysical Research Communications , 344 (2), 581–587
13.
Tang*†, J, Wang†, C, Feng†, Y, Yang†, W, Song†, H, Chen†, Z, Yu†, H, Pan,
X, Zhou, X, Wang, H, Wu, B, Wang, H, Zhao, H, Lin, Y, Yue, J, Wu, Z, He, X,
Gao, F, Khan, AH, Wang, J, Zhao, GP, Wang*, Y, Wang*, X, Chen, Z, Gao*,
G.F
, 2006, Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Medicine ， 3 (5), 668-676 (†shared the first author) ( With short title in the front cover: Streptococcus suis outbreak in China )
14.
Li X, Liu X, Sun F, Gao J, Zhou H, Gao GF , Bartlam M, Rao Z. 2006,Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor. Biochemical and Biophysical Research
Communications . 339(1):407-14
15.
Cole, DK, Rizkallah, PJ, Gao, F, Watson, NI, Boulter, JM, Bell, JI, Sami, M,
Gao*, G.F
& Jakobsen*, BK, 2006, Crystal structure of HLA-A*2402 complexed with a telomerase peptide. European Journal of Immunology, 36
(1), 170-179
16.
Liu*†, J, Xiao†, H, Lei†, F, Zhu, Q, Qin, K, Zhang, XW, Zhang, XL, Zhao, D,
Wang, G , Feng, Y, Ma, J, Liu, W, Wang, J, Gao *, G.F
, 2005, Highly pathogenic H5N1 influenza virus infection in migratory birds.
Science, 309
(5738), 1206 (†shared the first author)
17.
Ni, L, Zhao, L, Qian, Y, Zhu, J, Jin, Z, Chen, YW, Tien, P*, Gao*, G.F
, 2005,
Design and characterization of human respiratory syncytial virus entry inhibitors. Antiviral Therapy, 10 (7), 833-840
18.
Zhu, J, Jiang, X, Liu, Y, Tien, P*, Gao*, G.F, 2005, Design and characterization of viral polypeptide inhibitors targeting Newcastle disease virus fusion. Journal of Molecular Biology, 354 (3), 601-613
19.
Ni, L, Zhao, L, Gao, G.F
, Qian, Y*, Tien, P*, 2005, The antibodies directed against N-terminal heptad-repeat peptide of hRSV fusion protein and its analog-5-Helix inhibit virus infection in vitro. Biochemical and Biophysical
Research Communications, 331 (4), 1358-1364
20.
Ni, L, Gao*, G.F
, Tien, P*, 2005, Rational design of highly potent HIV-1 fusion inhibitory proteins: Implication for developing antiviral therapeutics.

Biochemical and Biophysical Research Communications, 332 (3), 831-836
21.
Zhang, Z, Xu, D, Li, Y, Jin, L, Shi, M, Wang, M, Zhou, X, Wu, H, Gao, G.F
,
Wang*, FS, 2005, Longitudinal alteration of circulating dendritic cell subsets and its correlation with steroid treatment in patients with severe acute respiratory syndrome. Clinical Immunology, 116 (3), 225-35
22.
Chu, F, Lou, Z, Gao, B, Bell, JI, Rao, Z, Gao*, G.F
, 2005, Complex assembly, crystallization and preliminary X-ray crystallographic studies of rhesus macaque MHC Mamu-A*01 complexed with an immunodominant
SIV-Gag nonapeptide. Acta Crystallographica Section F Structural Biology and Crystallization Communications, 61 (Pt6), 614–616
23.
Li, H, Zhou, M, Han, J, Zhu, X, Dong, T, Gao*, G.F
, and Tien, P* , 2005,
Generation of murine CTL by a hepatitis B virus-specific peptide and evaluation of the adjuvant effect of heat shock protein glycoprotein 96 and its terminal fragments. The Journal of Immunology ;174(1):195-204
24.
Gao*, G.F, 2005, Filling the hole: evidence of a small molecule binding to the fusion core pocket in human respiratory syncytial virus. Expert Opinion on
Investigational Drugs 14(2): 195-197
25.
Yuan, F., Lou, Z., Li, X., Chen, Y., John I. Bell, Zihe Rao, Gao*, G.F
, 2005,
Refolding ， crystallization and preliminary X-ray structural studies of the West
Nile virus envelope(E) protein domain Ⅲ . Acta Crystallographica Section F
Structural Biology and Crystallization Communications F61 ， 421-423
26.
Li, S., Zhu, J .
, Peng, Y., Cui, S., Wang, C., Gao*, G.F
, Tien, P*. 2005,
Characterization of BIV Env core: Implication for mechanism of
BIV-mediated cell fusion. Biochemical and Biophysical Research
Communications (BBRC) 329: 603-609
27.
Cole, DK, Rizkallah, PJ, Sami, M, Lissin, NM, Gao, F., Bell, JI, Boulter, JM,
Glick, M, Vuidepot, AL, Jakobsen, BK and Gao*, G.F
, 2005, Crystallization and preliminary X-ray structural studies of a high-affinity CD8ααco-receptor to pMHC. Acta Crystallographica Section F Structural Biology and
Crystallization Communications, 61 (Pt 3), 285-287.
28.
Ni, L., Zhu, J., Zhang, J., Yan, M., Gao*, G.F
, Tien, P*, 2005, Design of recombinant protein-based SARS-CoV entry inhibitors targeting the heptad-repeat regions of the spike protein S2 domain. Biochemical and
Biophysical Research Communications (BBRC) 330: 39-45.
29.
Wang, X., Bai, Y., Zhang, G., Zhao, J., Wang, M., Gao*, G.F
. 2005, Structure and function study of paramyxovirus fusion protein heptad repeat peptides.
Archives of Biochemistry and Biophysics(ABB) 436: 316-322
30.
Xu,D.,Zhang,Z.,Jin,L.,Chu,F.,Mao,Y.,Wang,H.,Liu,M.,Wang,M.,Zhang,L.,
G.F. Gao and Wang,F.S.2005,Persistent shedding of viable SARS-CoV in urine and stool of SARS patients during the convalescent phase. European
Journal of Clinical Microbiology & Infectious Diseases 24:165-171

31.
Liu Y, Xu Y, Zhu J, Qiu B, Rao Z, Gao, G.F
, Tien P, Crystallization and preliminary X-ray diffraction analysis of central structure domains from mumps virus F protein. 2005, Acta Crystallograph Sect F Struct Biol Cryst
Commun , 61(Pt 9):855-7
32.
Xu, Y., Lou, Z., Liu, Y., Pang, H., Tien, P., Gao, G.F
, & Rao*, Z., 2004
，
Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core. Journal of Biological Chemistry (JBC) 279(47):49414-9
33.
Xu, Y., Liu, Y., Lou, Z., Qin, L., Li, X., Bai, Z., Tien, P., Gao*, G.F.
& Rao*,
Z., 2004, Structural basis for coronavirus-mediated virus membrane fusion: crystal structure of MHV spike protein fusion core, Journal of Biological
Chemistry (JBC) 279 (29):30514-22.
34.
Cole, D.K. & Gao*, G.F.
, 2004, CD8: Adhesion molecule, co-receptor and immuno-modulator (invited review), Cellular and Molecular Immunology 1
(2): 81-88.
35.
Pang, H., Bartlam, M., Zeng, Q., Miyatake, H., Hisano, T., Miki, K., Wong,
L-L, Gao, G.F
. & Rao, Z., 2004, Crystal structure of human pirin: an iron binding nuclear protein and transcription cofactor. Journal of Biological
Chemistry (JBC) 279 (2): 1491-1498.
36.
Xu, D., Zhang, Z., Chu , F., Li, Y., Jin, L., Zhang, L., Gao, G.F
. & Wang,
F.-S., 2004, Genetic variation of SARS coronavirus in Beijing hospital,
Emerging Infectious Diseases 10 (5): 789-794.
37.
Gao, G.F.
, 2004, Just folding back: Convergence of viral fusion mechanisms
(Monitor), Drug Discovery Today 9: 288.
38.
Xu, Y., Zhu, J., Liu, Y., Lou, Z., Yuan, F., Liu, Y., Cole, D.K., Ni, L., Su, N.,
Qin, L., Li, X., Bai, Z., Bell, J.I., Pang, H., Tien, P., Gao*, G.F
. & Rao*, Z.,
2004, Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from severe acute respiratory syndrome (SARS) coronavirus, Biochemistry 43(44):14064-71.
39.
Zhu, X., Li, C., Lang, Z., Gao*, G.F
. & Tien*, P., 2004, Significant correlation between expression level of HSP gp96 and the progression of hepatitis B virus induced diseases, World Journal of Gastroenterology 10 (8):
1141-1145.
40.
Xu, Y., Cole, D.K., Lou, Z., Liu, Y., Qin, L., Li, X., Bai, Z., Yuan, F., Rao*,
Z. & Gao*, G.F
. , 2004 ， Construct design, biophysical, and biochemical characterization of the fusion core from mouse hepatitis virus (a coronavirus) spike protein. Protein Expression and Purification 38(1):116-22.
41.
Xu, Y., Gao, S., Cole, D.K., Zhu, J., Su, N., Wang, H., Gao*, G.F
. & Rao*,
Z., 2004, Basis for fusion inhibition by peptides: analysis of the heptad repeat regions of the fusion proteins from Nipah and Hendra viruses, newly emergent zoonotic paramyxoviruses, Biochemical and Biophysical Research
Communications (BBRC) 315 (3): 664-670

42.
Zhu, J., Xiao, G., Xu, Y., Yuan, F., Zheng, C., Liu, Y., Cole, D.K., Yan, H.,
Bell, J.I., Rao, Z., Tien*, P. & Gao*, G.F
. , 2004, Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein and identification of potent peptide inhibitors, Biochemical and Biophysical
Research Communications (BBRC) 319: 283-288.
43.
Liu, Y., Zhu, J., Feng, M., Tien, P. & Gao*, G.F
. , 2004, Six-helix bundle assembly and analysis of the central core of mumps virus fusion protein.
Archives of Biochemistry and Biophysics (ABB) 421: 143-148.
44.
Yan, H., Xiao, G., Zhang, J., Hu, Y., Yuan, F., Cole, D.K., Zheng*, C. &
Gao*, G.F
. , 2004, SARS coronavirus induces apoptosis in Vero E6 cells,
Journal of Medical Virology 73: 323-331.
45.
Xu, Y., Lou, Z., Liu, Y., Cole, D.K., Su, N., Qin, L., Li, X., Bai, Z., Rao, Z. &
Gao*, G.F
. , 2004, Crystallization and preliminary crystallographic analysis of the fusion core from two new zoonotic paramyxoviruses, Nipah virus and
Hendra virus. Acta Crystallographica Section D Biological Crystallography
D60: 1161-1164 .
46.
Zhou, M., Xu, Y., Lou, Z., Cole, D.K., Li, X., Liu Y.,Tien, P., Rao*, Z. &
Gao*, G.F
. , 2004, complex assembly, crystallization and preliminary X-ray crystallographic studies of MHC H-2 k d complexed with an HBV core nonapeptide, Acta Crystallographica Section D Biological Crystallography
60(Pt 8):1473-5.
47.
Wang, X., Xu, Y., Cole, D.K., Lou, Z., Liu, Y., Rao, Z., Wang*, M. & Gao*,
G.F.
, 2004, Biochemical, biophysical and preliminary X-ray crystallographic analyses of the fusion core of Sendai virus F protein, Acta Crystallographica
Section D Biological Crystallography 60(Pt 9):1632-5.
48.
Xu, Y., Bai, Z., Qin, L., Li, X., Gao*, G.F
. & Rao*, Z., 2004, Crystallization and preliminary crystallographic analysis of the fusion core of the spike protein of the murine coronavirus mouse hepatitis virus (MHV). Acta
Crystallographica Section D Biological Crystallography 60 (Pt 11):2013-5.
49.
Xu, Y., Su, N., Qin, L.,Bai, Z., Gao, G.F.
, & Rao*, Z., 2004, Crystallization and preliminary crystallographic analysis of the heptad-repeat complex of
SARS coronavirus spike protein. Acta Crystallographica Section D
Biological Crystallography D60 (Pt 12 Pt 2):2377-9.
50.
王晓佳，张卫红，汪明，高福，
2004
，囊膜病毒膜融合的分子机制。 生物
化学与生物物理进展
31 （ 6 ）： 482-491 。
51.
Yang, H., Yang, M., Ding, Y., Liu, Y., Lou, Z., Zhou, Z., Sun, L., Mo, L.,Ye,
S., Pang, H., Gao, G.F
. , Anand, K., Bartlam, M., Hilgenfeld, R. & Rao, Z.,
2003, The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor. Proceedings of National Academy of Sciences USA (PNAS) 100 (23): 13190-13195.

52.
Ding, Y., Xu, G., Yang, M., Yao , M., Gao, G.F
. , Wang, L., Zhang, W. &
Rao, Z., 2003, Crystal structure of the ectodomain of human FcRI. Journal of
Biological Chemistry (JBC) 278 (30): 27966-27970. (with front cover illustration).
53.
Wang, E., Sun, X., Qian Y., Zhao, L., Tien, P. & Gao* , G.F
. , 2003, Both heptad repeats of human respiratory syncytial virus fusion protein are potent inhibitors of viral fusion. Biochemical and Biophysical Research
Communications (BBRC) 302: 469-475.
54.
Zhu, J .
, Ding, Y., Gao, F., Wu, T., Zhang, C.W.-H., Tien, P., Rao, Z. & Gao*
, G.F
. , 2003, Crystallization and preliminary X-ray crystallographic analysis of the trimer core from measles virus fusion protein. Acta Crystallographica
Section D Biological Crystallography D59: 587-590.
55.
Li, P., Zhu, J., Wu, B., Gao, F., Tien, P., Rao, Z. & Gao*, G.F.
, 2003,
Crystallization and preliminary X-ray diffraction analysis of post-fusion
6-helix bundle core structure from Newcastle disease virus F protein. Acta
Crystallographica Section D Biological Crystallography D59: 1296-1298.
56.
Zhu, J., Li, P., Wu, T., Gao, F., Ding Y., Zhang, C.W.-H., Rao, Z., Gao*, G.F.
& Tien*, P., 2003, Design and analysis of post-fusion 6-helix bundle of heptad repeat regions from Newcastle disease virus F protein. Protein Engineering
16: 373-379. *Shared correspondence author.
57.
Zhu, J., Zhang, C.W.-H., Rao, Z., Tien, P. & Gao*, G.F
. , 2003, Biochemical and biophysical analysis of heptad repeat regions from the fusion protein of
Menangle virus, a newly emergent paramyxovirus. Archives of Virology 148:
1301-1316.
58.
Gao,* G.F
. , Rao, Z. & Bell, J.I., 2002, Molecular coordination of cβ T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands. Trends in Immunology 23: 408-413. *Correspondence author
59.
Gao, G.F
., 2002, CD8αα and CD8 αβ: truly different? (News and comment).
Trends in Immunology 23: 177.
60.
Gao, G.F.
& Rao, Z., 2002, Seeing the change: TCR binds pMHC with an
‘induced-fit' (News and comment).
Trends in Immunology 23: 281.
61.
Rao, Z. & Gao, G.F
. , 2002, Lipid-antigen presentation by CD1 is crystal clear (News and comment). Trends in Immunology 23: 473.
62.
Jiang, S., Borthwick , N.J. , Morrison, P., Gao, G.F
. & Steward, M.W., 2002,
Virus-specific CTL responses induced by an H-2Kd-restricted, motif-negative
15-mer peptide from the fusion protein of respiratory syncytial virus . Journal of General Virology 83: 429-438.
63.
Yu, M., Wang, E., Liu, Y., Cao, D., Jin, N., Zhang, C.W.-H, Bartlam, M.,
Rao, Z., Tien, P. & Gao*, G.F.
, 2002, Six-helix bundle assembly and characterization of heptad repeat regions from the F protein of Newcastle disease virus . Journal of General Virology 83: 623-629.

64.
Zhu, J., Zhang, C.W.-H., Qi, Y., Tien, P. & Gao*, G.F
. , 2002, The fusion protein core of measles virus forms stable coiled coil trimer. Biochemical and
Biophysical Research Communications (BBRC) 299: 897-902.
65.
Meng, S.-D., Song, J., Rao, Z., Tien, P. & Gao*, G.F
. , 2002, Three-step purification of gp96 from human liver tumor tissues suitable for isolation of gp96-bound peptides. Journal of Immunological Methods 264: 29-35.
66.
Meng, S.-D., Gao, T., Gao, G.F
. & Tien*, P., 2001, HBV-specific peptide associated with heat-shock protein gp96. The Lancet 357: 528-529.
67.
Lin, C.-L., Sewell, A.K., Gao, G.F
. , Whelan, K., Phillips, R.E. & Austyn,
J.M., 2000, Macrophage-tropic HIV induces and exploits dendritic cell chemotaxis. Journal of Experimental Medicine 192: 587-593.
68.
Gao, G.F
. , Willcox, B.E., Wyer, J.R., Boulter, J.M., O'Callaghan, C.A.,
Maenaka, K., Stuart, D.I., Jones, E.Y., van der Merwe, P.A., Bell, J.I. &
Jakobsen, B.K., 2000, Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8αα Journal of Biological Chemistry
(JBC) 275: 15232-15238.
69.
Gao,* G.F
. & Jakobsen, B.K., 2000, Molecular interactions of coreceptor
CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunology Today 21 (12): 630-636. *Correspondence author
70.
Sewell, A.K., Gerth, U.C., Price, D.A., Purbhoo, M.A., Boulter, J.M., Gao,
G.F. , Bell, J.I., Phillips, R.E. & Jakobsen, B.K., 1999, Antagonism of cytotoxic T-lymphocyte activation by soluble CD8. Nature Medicine 5:
399-404.
71.
Wyer* J.R., Willcox*, B.E., Gao*, G.F
. , Gerth, U.C., Davis, S.J., Bell, J.I., van der Merwe, P.A. & Jakobsen, B.K., 1999, T cell receptor and coreceptor
CD8 αα bind peptide-MHC independently and with distinct kinetics.
Immunity 10: 219-225. *Shared first author
72.
Maenaka, K., Juji, T., Nakayama, T., Wyer, J.R., Gao, G.F
. , Maenaka, T.,
Zaccai, N.R., Kikuchi, A., Yabe, T., Tokunaga, K., Tadokoro, K., Stuart, D.I.,
Jones, E.Y. & van der Merwe, P.A., 1999, Killer cell immunoglobulin receptors and T cell receptors bind peptide-Major Histocompatibility Complex class I with distinct thermodynamic and kinetic properties. Journal of
Biological Chemistry (JBC) 274: 28329-28334.
73.
Willcox*, B.E., Gao*, G.F
. , Wyer, J.R., O'Callaghan, C.A., Jones, E.Y., van der Merwe, P.A., Bell, J.I. & Jakobsen, B.K., 1999, Production of soluble a b
T-cell receptor heterodimers suitable for biophysical analysis of ligand binding. Protein Science 8: 2418-2423. *Shared first author
74.
Willcox*, B.E., Gao*, G.F
. , Wyer, J.R., Ladbury, J.E., Bell, J.I., Jakobsen,
B.K. & van der Merwe, P.A., 1999, TCR binding to peptide-MHC stabilizes a

flexible recognition interface. Immunity 10: 357-365. *Shared first author
75.
McGuire, K., Holmes, E.C., Gao, G.F
. , Reid, H.W. & Gould, E.A., 1998,
Tracing the origins of louping ill virus by molecular phylogenetic analysis.
Journal of General Virology 79: 981-988.
76.
Gao, G.F
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