Haitoglou Kostas - Associate Professor
Name: Haitoglou Kostas
Position: Associate Professor
Academic institution: Medical School, Aristotle University of Thessaloniki
Post-graduate studies: PhD in Biochemistry, Medical School, Aristotle
University of Thessaloniki
Graduate studies: B.Sc in Biology, Dept. of Biology, Aristotle University of
Thessaloniki
Research
interests:
Protein
analysis
(chromatographic
methods,
electrophoresis, Western blotting, 2-D gel electrophoresis and analysis) and
expression
Publications: 7
Citations: 106
Invited speaker/Membership
Congresses-Conferences
Scientific Commitee of the 1st Scientific Congress of the Medical School of
Aristotle University of Thessaloniki, 2002
Organizing Commitee of the Scientific meeting entitled «Cellular communication
and signaling pathways» organized by the Hellenic Society of Biochemistry and
Molecular Biology, Thessaloniki 2009
Invited Speaker
Haitoglou C. Methodologies of proteomic analysis. Lecture presented at the 3rd
Panhellenic Congress of the Hellenic Society of Medical Biochemistry, Athens,
Greece, 26-29 March 2009
Haitoglou C. Methods in proteomic analysis. Lecture presented at the 5th
Scientific Congress of the Medical School of Aristotle University of Thessaloniki,
Thesasloniki, 2-5 April 2009
Haitoglou C. Proteomics: New tool in biopathology. Lecture presented at the 23rd
Postgraduate Seminar in Medical Biopathology organized by the Society of
Medical Biopathology of Northern Greece, Thessaloniki, Greece, 5-7 December
2008
Haitoglou C. Electrophoresis: General principles and clinical applications. Lecture
presented at the 8th Postgraduate Seminar in Medical Laboratory Diagnostics
and Microbiology organized by the Microbiology Society of Thessaloniki,
Thessaloniki, Greece, 5-7 December 2008
Member of the following Scientific Societies
Hellenic Society of Biochemistry and Molecular Biology
Hellenic Society of Pharmacology
Panhellenic Association of Biologists (Bioscientists)
Publications
JOURNALS
1. Kovatsi L, Georgiou E, Ioannou A, Haitoglou C, Tzimagiorgis G, Tsoukali H,
Kouidou S. (2010) p16 promoter methylation in Pb2+-exposed individuals. Clin
Toxicol (Phila) 48(2):124-8
2. Palassopoulou M, Haitoglou C, Papageorgiou G, Dimitriadou A. (2003) PLP
induced inhibition of thymidylate synthase activity in T lymphocytes. Eur J
Inflamm 1(2):79-83
3. Palassopoulou M, Haitoglou C, Papageorgiou G, Dimitriadou A. (2002) The
effect of 4-deoxypyridoxine phosphate on the activity of thymidylate synthase in T
lymphocytes. Proceedings of the 2nd Panhellenic Conference in Pharmacology,
in Review of Clinical Pharmacology and Pharmacokinetics 16(1):89-90
4. Palasopoulou M, Haitoglou C, Papageorgiou G, Dimitriadou A. (2001)
Inhibition of enzymes of thymidilate cycle. Scientific Annals of the Faculty of
Medicine (AUMJ) 28(1):49-58
5. Haitoglou C, Gounaris I, Felekis I. (2000) Hyperomocysteinaimia: Risk factor
for atherogenesis. Scientific Annals of the Faculty of Medicine (AUMJ) 27(1):7989
6. Trakatellis A, Exindari M, Haitoglou C, Christodoulou D, Dimitriadou A. (1995)
Serine hydroxymethyltransferase (SHMT) as a precious indicator of
antiproliferative or immunosuppressive potency of various compounds.
International Journal of Immunopathology and Pharmacology 8(1):31-7
7. Koliakos G, Konstas AGP, Dimitrakoulias N, Haitoglou C, Triantos A. (1994)
Biochemical studies on the pathogenesis of exfoliation syndrome. Ophthalmology
6(4):419-26
8. Trakatellis A, Dimitriadou A, Exindari M, Christodoulou D, Malissiovas N,
Antoniadis A, Haitoglou C. (1994) Effect of combination of deoxypyridoxine with
known antiproliferative or immunosuppressive agents on lymphocyte serine
hydroxymethyltransferase. Postgrad Med J 70 (Suppl. 1):S89-S92
9. Kosmopoulou I, Koliakos G, Haitoglou C, Christodoulou D, Dimitriadou A,
Trakatellis A. (1994) Rat liver endoplasmic reticulum protein kinases. Int J
Biochem 26(3):403-14
10. Haitoglou C, Tsilibary E, Brownlee M, Charonis A. (1992) Altered cellular
interactions between endothelial cells and nonenzymatically glycosylated
laminin/type IV collagen. J Biological Chemistry 267(18):12404-7
ABSTRACTS
1. Kritis A, Angelidou E, Dimitraki P, Basgiouraki A, Haitoglou C, Vlahou A,
Albani M. Glutamate induced excitotoxicity on PC12 cells evokes downregulation
of Hsc70 and modulation of other heat shock proteins expression. A proteomics
approach. 61st Meeting of the Hellenic Society of Biochemistry and Molecular
Biology, Alexandroupoli, Greece, 15-17 October 2010. Abstracts p.62(P49)
2. Touplikioti P, Papazisis K, Kontovinis L, Koumpanaki M, Patakiouta F,
Mouratidou D, Haitoglou C. Expression of Notch receptors in primary breast
cancer and correlation to pathologic features. 100th Annual Meeting of the
American Association of Cancer Research (AACR), 2009, Denver CO, USA
3. Krikelis D, Tzimagiorgis G, Georgiou E, Anzel I, Destouni H, Agorastos T,
Haitoglou C, Kouidou S. Frequent presence of incomplete, but not full length
HPV-16 E7 ORFs in lung carcinomas: ‘memories’ of viral infection? FEBS
Journal 275(Suppl.1);283A, 2008
4. Fedonidis K. Georgiou E, Ioannou A, Kovatsi L, Fragou K, Agorastos T,
Girousi S, Voulgaropoulos A, Tsoukali E, Haitoglou C, Tzimagiorgis G, Kouidou
S. p16 methylation among high risk, cigarette smokers and heavy metal-exposed
individuals. FEBS Journal 275 (Suppl.1):409A, 2008
5. Ioannou A, Alexiadou D, Girousi S, Fragou K, Haitoglou C, Tzimagiorgis G,
Voulgaropoulos A, Kouidou S. Electrochemical and thermal analysis of
cancerous and normal genomic DNA and PCR-fragments of variable methylcytosine content. 59th Meeting of the Hellenic Society of Biochemistry and
Molecular Biology, Athens, 2007. Abstracts 54:117
6. Touplikioti P, Tzimagiorgis G, Kouidou S, Haitoglou C. Expression of DNAmethyltransferases in lung carcinoma specimens. 59th Meeting of the Hellenic
Society of Biochemistry and Molecular Biology, Athens, 2007. Abstracts 54:282
7. Georgiou E, Tzimagiorgis G, Valeri R, Barbetakis N, Antzel I, Tsilikas C,
Sarikos G, Destouni C, Haitoglou C, Spanos G, Dimitriadou A, Kouidou S. Ηigh
frequency of p16 promoter hypermethylation in bronchial washing and lung
cancer specimens. 54th Meeting of the Hellenic Society of Biochemistry and
Molecular Biology, Ioannina, 2002. Proceedings 49:97-103
8. Nella C, Haitoglou C. The role of telomerase in ageing and cancer. 7th
Scientific Medical Students’ Conference, Larissa, Greece, 27-29 April 2001.
Abstracts p.97(42)
9. Katsiki N, Haitoglou C. Nonenzymatic protein glycosylation, diabetic
complications and modern treatment views. 6th Scientific Medical Students’
Conference. Thessaloniki, 12-14 May 2000. Abstracts p.90(35)
10. Felekis I, Haitoglou C. The role of nitric monoxide (NO) in the function of
blood vessels and in the progmosis of atherogenesis. 5th Scientific Medical
Students’ Conference. Abstracts, p 102, 1999
11. Koukos G, Tzikas S, Haitoglou C. Bacterial infections and cardiovascular
diseases. 5th Scientific Medical Students’ Conference. Abstracts p.102, 1999
12. Mparkas C, Tsitas N, Lasxos C, Haitoglou C. Proteases and metastasis. 5th
Scientific Medical Students’ Conference. Abstracts p.113, 1999
13. Felekis I, Haitoglou C. Hyperomocysteinaimia: Risk factor for atherogenesis.
4th Scientific Medical Students’ Conference. Ioannina, 3-5 April 1998. Abstracts
p.69(31)(oral presentation)
13. Palassopoulou M, Haitoglou C, Christodoulou D, Dimitriadou A, Trakatellis A.
The effect of pyridoxine (B6) and deoxypyridoxine (dB6) on the catalytic activity
of thymidylate synthase in stimulated T lymphocytes. 11th Balkan Biochemical
Biophysical Days, Thessaloniki, Greece, May 15-17, 1997. Abstracts, p.129(400)
14. Tsilibary E, Charonis A, Haitoglou CS. Defective polymerization of type IV
collagen following nonenzymatic glycosylation. 52nd Annnual Meeting of the
American Diabetes Association, San Antonio, TX, USA, June 20-23, 1992.
Diabetes 41(suppl 1):80A(291)
15. Charonis AS, Haitoglou CS, Tsilibary EC. Nonenzymatic glycosylation of
laminin and type IV collagen reduces their ability to promote endothelial cell
adhesion. 14th International Diabetes Federation Congress, Washington, DC,
USA, June 23-28, 1991. Diabetes 40(suppl 1):123A(490)
16. Charonis A, Kouzi-Koliakos N, Haitoglou C, Anderson S, Tsilibary E.
Structural/ functional changes of matrix proteins by glycation. 21st Annual
Meeting of the American Aging Association, Denver, CO. USA, October 9-12,
1991. Proceedings p.15(67)
17. Haitoglou C, Charonis A, Tsilibary. Functional alterations of type IV collagen
following nonenzymatic glycosylation. 31st Annual Meeting of the American
Society for Cell Biology, Boston MS, USA, December 8-12, 1991. J Cell Biol
115(3 Pt2):439a(2550)
18 Kosmopoulou-Charalambaki IK, Haitoglou CS, Christodoulou DT, Koliakos
GG, Dimitriadou-Vafiadou A, Trakatellis AC. Study of rat liver microsomal
proteins. 20th FEBS Meeting, Budapest, Hungary, August 19-24, 1990.
Abstracts, p.280(P-Th 181)
19. Charonis AS, Haitoglou CS, Tsilibary EC. Defective cell adhesion of
diabetically modified basement membrane molecules. Midwest Connective
Tissue Workshop, Chicago, Illinois, USA November 16-17, 1990
20. Charonis A, Tsilibary E, Koliakos G, Haitoglou C. Structural and functional
alterations of diabetically modified laminin. Proceedings of the 5th International
Symposium on Basement Membranes, Oulu, Finland, 1990
21. Dimitriadou A, Haitoglou C, Christodoulou D, Trakatellis A. Insulin effects on
phosphorylation of endoplasmic reticulum proteins. 6th Balkan Biochemical and
Biophysical Days, Plovdiv, 16-19 April 1985. Abstracts (3P33)
22. Koliakos G, Vlatsas G, Haitoglou C, Dimitriadou A, Trakatellis A. Effect of
insulin on phosphorylation-dephosphorylation of certain endoplasmic reticulum
proteins. 5th International Conference on Cyclic Nucleotides and Protein
Phosphorylation, Milan, June 27-July 1,1983. Advances in Cyclic Nucleotide and
Protein Phosphorylation Research 17A:160
23. Vlatsas G, Koliakos G, Haitoglou C, Christodoulou D, Dimitriadou A,
Trakatellis A. Insulin mediated changes in the membranes of endoplasmic
reticulum. 5th Balkan Biochemical and Biophysical Days, Thessaloniki, May 1113, 1983, Abstracts,p. 47
CHAPTERS/BOOKS
1. Haitoglou C. (2008) Proteomics: New diagnostic tool in biopathology.
Microbiological Chronicles 24:143-55
2. Dimitriadou A, Katopodi T, Kouidou-Andreou S, Karkanis G, Vavatsi-Christaki
N, Haitoglou C, Spanos P, Tzimagiorgis G. (2003). Lung Cancer: New aspects in
the elucidation of the molecular basis of the disease. Surgery Aspects: Prof.
Anastasios Aidonopoulos, Honors edition. University Studio Press p.120-8
3. Haitoglou C, Van Bragt PH. (1994) Protein electrophoresis: general principles
and clinical applications. Practical Course Notes, p.85-112
4. Haitoglou C, Van Bragt PH. (1994) Blotting techniques. Practical Course
Notes, p.113-28
5. Haitoglou C. (1993) Electrophoresis: General principles and clinical
applications. Microbiologial Chronicles 9:51-71
6. C. Haitoglou. Phosphorylation-dephosphorylation of endoplasmic reticulum
proteins and regulation. PhD thesis (1989) Medical School, Aristotle University,
Thessaloniki.