COURSE SECTION INFORMATION Laboratory Animal Husbandry Veterinary Assistant Professor’s Name: Leslie Wood DVM Luc Lemay woodl1@algonquincollege.com lemayl@algonquincollege.com Email: Course Number: Course Section: Phone: Academic Year: Office: Term: Out of Class Assistance: Please Email for an appointment VET0019 Academic Level: 2010 Fall 02 Section Specific Learning Resources – In-class The learning resources for this course are the same as those listed in the approved course outline available on Blackboard. related materials will be provided to the student as required and will consist of : Canadian Council on Animal Care website: http://www.ccac.ca/en/CCAC_Main.htm Websites and other on-line documents or videos Learning Schedule – In-class Week 1 Date Sept 9 Topic Introduction 2 Sept 16 Principles of Research Canadian Legislation CCAC 3 R’s Learning Resources 1) AALAS Brochure: Use of Animals in Biomedical research: Understanding the Issues http://www.aalas.org/pdf/08-00007.pdf 2) Animal Research Info Website http://www.animalresearch.info/en/medical/diseasesresearch 3) AALAS Brochure: Why More Vet Techs are Choosing Laboratory Animal Science http://www.aalas.org/pdf/vtc_brochure.pdf 4) Lab Animal Technician video http://www.aboutbioscience.org/laboratory_animal_technician.html 1) http://www.ccac.ca/en/CCAC_Programs/ETCC/PDFs/ETC_Modules.pdf Module 5 .. read sections a) “Animal Models in Biomedical Research” b) “Physical and Environmental Factors” c) “Animal Care and Handling Factors” 2) http://www.ccac.ca/en/CCAC_Programs/Assessment/CCACCFHS_Manual_e.pdf page 4 section 2.1 3) http://www.ccac.ca/en/CCAC_Programs/Assessment/CCACCFHS_Manual_e.pdf pg 2 section 1.4.1 and pg 4 section 4.1 4) http://www.ccac.ca/en/CCAC_Programs/Assessment/CCACCFHS_Manual_e.pdf pages 13-16, section 3.1-3.4 5) http://www.ccac.ca/en/alternatives/index.html read “Home” and “The 3 R’s Introduction” 1) Animal Research.Info http://www.animalresearch.info/en/science/animalsused/mouse 2) Animal Research Review Panel section 1.5 page 20-24 http://www.animalethics.org.au/__data/assets/pdf_file/0004/249898/draftguidelines-housing-mice.pdf 3) Handling and injections-photos and videos http://www.bva-awf.org.uk/resources/tutorials/BVA05-Mouse/Mouse.html 3 Sept 23 Mice: species characteristics Safe/proper handling Quiz 1 4 Oct 30 Mice: husbandry + environmental enrichment 1) CCAC Guide to the Care and Use of Experimental Animals Vol I http://www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GUIDES/ENGLI SH/V1_93/CHAP/CHIII.HTM Chapter III The Environment 2) CCAC Guide to the Care and Use of Experimental Animals Vol I http://www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GUIDES/ENGLI SH/V1_93/CHAP/CHIII.HTM Chapter VI Social and Behavioural Requirements of Experimental Animals A Introduction G Rodents and Rabbits 5 Oct 7 Rats: species characteristics Safe/proper handling 1) Animal Research Review Panel: Guidelines for the Housing of Rats in Scientific Institutions pg 14- 16 Section 1.5 pg 33-36 Section 3.5 http://www.animalethics.org.au/__data/assets/pdf_file/0014/222512/housingrats-scientific-institutions.pdf 2) Animal Welfare Foundation Practical Animal Handling in Small Mammals http://www.bva-awf.org.uk/resources/tutorials/BVA06-Rat/Rat.html 6 Oct 14 Rats: husbandry + environmental enrichment Animal Research Review Panel: Guidelines for the Housing of Rats in Scientific Institutions Sections 2.7, 2.8, 2.9 Environmental Enrichment: Section 3.6 http://www.animalethics.org.au/__data/assets/pdf_file/0014/222512/housingrats-scientific-institutions.pdf 7 8 Oct 21 Oct 28 Midterm Review Midterm Rabbits: species characteristics Safe handling 9 Nov 4 Rabbits: husbandry + environmental enrichment 10 Nov 11 Animal and Facility Records 11 Nov 18 Quiz 2 Laboratory Animal Allergies 1) CCAC Guidelines on the Care and Use of Experimental Animals Vol. http://www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GDLINES/VOL 2/rabbits.pdf Sections: A. Introduction B. Biology D. Husbandry E. Handling and Restraint F. Sampling and Manipulations 2) BVA Foundation-Animal Welfare Foundation http://www.bva-awf.org.uk/resources/tutorials/BVA08-Rabbit/Rabbit.html 3) NC3R’s Handling and Restraint of Rabbits Document http://www.nc3rs.org.uk/category.asp?catID=19 1)Rabbits: Good Practice for Housing and Care http://content.www.rspca.org.uk/cmsprd/Satellite?blobcol=urldata&blobheade r=application%2Fpdf&blobkey=id&blobnocache=false&blobtable=MungoBlob s&blobwhere=1232988745180&ssbinary=true 2) Rabbit Digestion - description http://www.peteducation.com/article.cfm?c=18+1799&aid=2932 Assignment 3 is an excellent resource but optional reading assignment. 3) Refining Rabbit Care. A resource for those working with rabbits in research. http://www.rspca.org.uk/servlet/BlobServer?blobtable=RSPCABlob&blobcol= urlblob&blobkey=id&blobwhere=1213709292078&blobheader=application/pd f 1) CCAC Animal identification Brochure http://www.ccac.ca/en/CCAC_Programs/ETCC/Module06/AIDB.html 2) Example of SOP from University of Guelph for Identification of Individual Mice https://www.uoguelph.ca/research/acs/guidelines/pdf/2009_Effective%20and %20Humane%20Identification%20of%20Genetically%20Modified%20Mice.p df 3) Scoring system: example of an objective way of monitoring animals http://campusvet.wsu.edu/infofac/post-op_care.htm Chart specific to post surgery or other invasive procedure 4) Micro-tattooing ears http://www.ketchum.on.ca/lab/mouse-ear-tattoo.html 5) Harlan Contact Bedding and Quality Control http://www.harlan.com/research_models_and_services/bedding_and_enrich ment_products/contact_bedding Reading assignments: 1) CCAC: Education, Training and Communication http://www.ccac.ca/en/CCAC_Programs/ETCC/Module04/12.html Module 04- Occupational health and Safety –Biological Hazards of Working With Experimental Animals Read up to and including rat bite fever Zoonoses 2) CCAC : Education, Training and Communication http://www.ccac.ca/en/CCAC_Programs/ETCC/Module04/16.html Module 04- Occupational health and Safety-Allergies to Laboratory Animals 3) Jackson Laboratories- Laboratory Animal Allergies (LAA) http://jaxmice.jax.org/faq/allergies.html 4) Material Safety Data Sheets – please keep this link as a reference for looking up contagious diseases http://www.phac-aspc.gc.ca/id-mi/index-eng.php 5) Worms and Germs Blog - http://www.wormsandgermsblog.com/ Excellent information put out by the Ontario Veterinary College and the Hamilton Public Health Department. 12 Nov 25 Preventing Disease Sanitation in the Animal Facility 1)CCAC Guide to the Care and Use of Experimental Animals Volume 1 Chapt V Laboratory Animal Care http://www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GUIDES/ENGLI SH/V1_93/CHAP/CHV.HTM#5D1 2) Research Techniques and Considerations-Sanitation and Vermin Control http://www.medaille.edu/vmacer/120_lec_21sanitation.htm Please be sure to open the links within this document. They provide some very useful information to help make the other content more clear. 13 Dec 2 Facility Layout 1.CCAC Guidelines Vol1- 1993 http://www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GUIDES/ENGLI SH/V1_93/CHAP/CHII.HTM 2. Guidelines on Laboratory Animal Facilities- characteristics, design and development 2003 – note much more detail http://www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GDLINES/Facili ties/PDFs/Facilities_Gdlines_Eng.pdf 14 Dec 9 Review 15 Dec 16 Final Examination Evaluation – Quiz 1 Midterm Quiz 2 Husbandry Participation Final Time 1-3 PM Room P 210 10 % 30 % 10 % 5 % 5 % 40 % Other Important Information Note: Pass is 60%. The lowest passing grade is a C- . Any marks lower than C- will result in an F. There are no D's in this course. Students failing to submit all required work in a course will receive a grade of Incomplete (I). A passing grade can only be achieved if all work is submitted on time, complete and produced at an academic level expected of college students. Students are permitted a maximum of one failure in a given course. Students failing a core course for the second time will be withdrawn from the program. Students who satisfy the criteria for being granted a supplemental will be permitted a maximum of three supplementals while they are in the program