Implementation Authorization - Unique Program - Page 1 Request for Implementation Authorization for a New Academic Degree Program [Unique] I. PROGRAM NAME AND DESCRIPTION AND CIP CODE Master of Science in Biomedical Informatics, CIP: 26.1103 The proposed program is designed to meet the rapidly growing need for professionals with preparation that integrates technological expertise in the information sciences / computer science, the biosciences and mathematical statistics with an understanding and ability to work in the clinical environment of the healthcare professions. The core program will feature a two semester sequence of courses specifically designed to bring together clinicians and researchers in teams, applying new developments in informatics theory to clinical practice. A common theme among the constituencies surveyed to understand the needs to be served by this program was the need for integrating theory and practice in biomedical informatics. The MS Program in Biomedical Informatics at ASU will address this theme with the core curriculum, and with two concentrations: one clinical that addresses the need for application, the other analytic that addresses the need for developmental understanding. This objective of integrating the clinical and analytic tracks will be challenging, but is strongly supported by our collaborators including: the University of Arizona College of Medicine, Phoenix Program; Mayo Clinic; Barrow Neurological Institute; and Banner Health. Though challenging, this approach will make the MS Program in Biomedical Informatics at ASU distinctive, if not unique, among biomedical informatics programs in the United States. Building on the core program students will have the option of following either of two concentrations: a clinical concentration for immediate professional practice applying biomedical informatics in the healthcare professions (e.g., hospital information systems, nursing informatics, public health informatics, medical imaging, laboratory instrumentation systems). Graduates with this concentration will typically enter or continue professional careers in clinical practice. an analytical concentration preparatory to a research career in areas such as biostatistical analysis, data mining in health records, medical imaging, genomic analysis, and epidemiological informatics. Graduates with this concentration will typically come members of research groups in the rapidly expanding biomedical research and development industry, or continue on for the Ph.D. Graduates will contribute to the growth of Bioscience and development of the healthcare professions in Arizona. Training in these areas has been identified as a significant need, and key to opportunities for economic development. The ASU Biomedical Informatics program will be centered at the Phoenix Biomedical Campus of the Arizona University System (PBCAUS), and will collaborate with the University of Arizona College of Medicine, Phoenix Program, ASU Colleges of Nursing and Liberal Arts and Sciences, TGen, and clinical partners. Implementation Authorization - Unique Program - Page 2 A. DEGREE(S), DEPARTMENT AND COLLEGE AND CIP CODE Master of Science Department of Biomedical Informatics / School of Computing and Informatics Ira A. Fulton School of Engineering CIP code: 26.1103 (Bioinformatics) B. PURPOSE AND NATURE OF PROGRAM The proposed program is designed to meet the rapidly growing demand for professionals with preparation that integrates technological expertise in the information sciences / computer science, the biosciences and mathematical statistics with an understanding and ability to work in the clinical environment of the healthcare professions. The program will provide students an opportunity to develop and augment skills and background from the companion disciplines that contribute to this major, and build a common, integrated foundation of knowledge for professional practice, further study, and contribute to research in this emerging discipline. C. PROGRAM REQUIREMENTS -- List the program requirements, including minimum number of credit hours, required courses, and any special requirements, including theses, internships, etc. 1. Admission Students entering the program must have earned a baccalaureate degree with at least a 3.0 GPA from a regionally accredited institution, have developed organizational skills and garnered team experience, and mastered effective oral and written communication skills. Applications will be reviewed and evaluated by an admissions committee based upon academic performance and background preparation, along with a statement of purpose for pursuing the program, subject to the availability of seats in the program. Students entering the program need to have backgrounds and working understanding in several contributing disciplines: Core concepts of computer programming, data structures and algorithms (similar to CSE 200 at ASU), Fundamentals of genetics (equivalent to BIO 187 + 188 at ASU), Introductory probability and statistics (equivalent to STP 226, 231, 326 or 420), Mathematical foundation for information scientists (similar to SCI 200, pending approval as part of proposed undergraduate SCI Certificate), or mathematical methods for geneticists (equivalent to MAT 351 at ASU) Concepts of patient care processes, as demonstrated by coursework or practice in one of the healthcare professions Implementation Authorization - Unique Program - Page 3 Students may be admitted conditionally with deficiencies in two of the background areas above, and will automatically convert to regular admission when the background courses are completed with grades of B (3.0) or better. 2. Program Minimum credit hours: 30 Required courses, both concentrations: BMI 510 (new) Introduction to Bioinformatics BMI 520 (new) Theory of Informatics in Clinical Practice I BMI 521 (new) Theory of Informatics in Clinical Practice II SCI 410 (new – proposed course as part of SCI Certificate) Information and Data Management HSM 561 Biostatistics I BMI 585 (new) Bioethics and professional seminar o 1 credit in each of three semesters) -- 18 credits (3 credits) (3 credits) (3 credits) (3 credits) (3 credits) (3 credits) Analytical Concentration -- 12 credits HSM 571 Biostatistics II (3 credits) Electives (3 credits) 5xx courses from Analytical Electives column in table in section D. Current Courses and Existing Programs BMI 592 Research (3 credits) BMI 599 Thesis (3 credits) Clinical Concentration -- 12 credits BMI 540 (new) Health Information Systems (3 credits) BMI 541 (new) Health Info. Sys. Management (3 credits) BMI/NUR 538 Evidence Based Practice (3 credits) BMI 593 Applied Project (3 credits) addressing a clinical informatics need using the understanding of biomedical informatics developed through the program CURRENT COURSES AND EXISTING PROGRAMS -- List current course and existing university programs which will give strengths to the proposed program. Programs 1. 2. 3. 4. 5. 6. 7. Biology Bioengineering Computational Biology Computer Science Health Sector Management Industrial Engineering Nursing Implementation Authorization - Unique Program - Page 4 8. Quantitative Business Analysis 9. Statistics and Probability Course # and Title Clinical Elective Biology BIO 508 Scientific Data Presentation BIO 545 Populations: Evolutionary Genetics BIO 547 Techniques in Evolutionary Genetics BIO 552 Developmental Genetics BIO 591 Controversy in Biotechnology, Health, and Developing Countries X Analytical Elective X X X X X BIO 591 Time Series Analysis BIO 594 Statistical Methods in Molecular Evolutionary Genetics X X BIO 598 Visualization and Computation Biomedical Engineering BME 566 Medical Imaging Instrumentation BME 568 Medical Imaging BME 598 Analytical and Diagnostic Instrumentation in Bioengineering X X X BME 598 Intro to Molecular, Cellular and Tissue Engineering BME 598 Modeling and Simulation of Physiological Systems X Computational Biology CBS 520 Modeling and Computational Biology X CBS 521 Problem Solving in Computational Biosciences X CBS 530 Introduction to Structural and Molecular Biology CBS 598 Applications of AI to Molecular Biology X CBS 598 Database Management CBS 598 Databases: Biological Applications CBS 598 Genomics: Sequencing and Mapping CBS 598 Mathematical Biology I CBS 598 Mathematical Methods for Genetic Analysis X X CBS 598 Scientific Computing-Bioinformatics Computer Information Systems CIS 502 Management Information and Decision Support Systems X CIS 512 Intelligent Decision Systems and Knowledge Management X CIS 520 Systems Design and Evaluation X X Implementation Authorization - Unique Program - Page 5 CIS 535 Distributed and Mixed-Media Information Systems X Computer Science Courses CSE 591 Computational Molecular Biology CSE 591 Data Mining CSE 591 Data Warehousing and Data Mining CSE 591 Genomics: Sequencing and Mapping CSE 591 Random Approximate Algorithms CSE 591 Semantic Web Mining CSE 598 Introduction to Data Mining Health Sector Management HSM 505 Managerial and Population Epidemiology HSM 522 Health Sector Information and Knowledge Management HSM 540 Health Care Outcomes HSM 560 Health Services Administration and Policy HSM 572 Bioinformatics and Microarray HSM 566 Basic Principles of Epidemiology Industrial Engineering IEE 511 Analysis of Decision Process IEE 572 Design of Engineering Experiments IEE 578 Regression Analysis IEE 598 Data Mining: Analysis of Massive Data Sets Mathematics Courses MAT 598 Math Biology II MAT 598 Mathematical Methods for Genetic Analysis MAT 598 Population Biology MAT 598 Self-Organization in Biological Systems Quantitative Business Analysis QBA 525 Applied Regression Models QBA 530 Experimental Design Statistics and Probability STP 526 Theory of Statistical Linear Models STP 530 Applied Regression Analysis STP 531 Applied Analysis of Variance X X X X X X X X X X X X X X X X X X X X X X X X X X Implementation Authorization - Unique Program - Page 6 D. NEW COURSES NEEDED -- List any new courses which must be added to initiate the program; include a catalog description for each of these courses. BMI 510 Introduction to Biomedical Informatics (3 credits) Fundamentals of informatics applied to health care, including computer-based medical records, knowledge-based systems, telehealth, decision support, human-computer interfaces, systems integration, and digital libraries. BMI 520 Theory of Informatics in Clinical Practice I (3 credits) A survey course exploring transformational leadership skills, ethics and applied informatics in a merged culture of healthcare and computer science. Prerequisite: BMI 510 BMI 521 Theory of Informatics in Clinical Practice II (3 credits) In-depth examination and application of transformational leadership skills, ethics and applied informatics in a merged healthcare and computer science culture. Prerequisite: BMI 520 BMI 530 Introduction to Biomedical Imaging Informatics (3 credits) Physical principles, image reconstruction techniques, and clinical applications of the most commonly used medical imaging modalities. Prerequisite: BMI 510 BMI 540 Health Information Systems (3 credits) Clinical database concepts. Full-text databases, distributed DB services. Architectures of clinical information systems. Reliability and availability, security. Integration of multimodal information. BMI 541 Health Information Systems Management (3 credits) Implementation, management, and evaluation of clinical information systems. Project management, human and financial resource allocation, organizational change, group processes. Evaluation of clinical information systems impact. Prerequisite: BMI 520, BMI 540. BMI 585 Bioethics / Prof. Seminar (1 unit, may be repeated up to 6 credit hours) Graduate level topics in Biomedical Informatics research and ethics presented by distinguished lecturers working in the field. Implementation Authorization - Unique Program - Page 7 E. REQUIREMENTS FOR ACCREDITATION -- Describe the requirements for accreditation if the program will seek to become accredited. Assess the eligibility of the proposed program for accreditation. No professional accreditation is available or sought. II. STUDENT LEARNING OUTCOMES AND ASSESSMENT A. What are the intended student outcomes, describing what students should know, understand, and/or be able to do at the conclusion of this program of study? An initial list of skills was developed based upon interviews with healthcare industry leaders who will be hiring graduates from this program and evaluation of similar programs at universities to which graduates of this program would apply for further graduate work leading to a research career. These skills were grouped into categories and a number of student outcomes have been identified. The intended student outcomes include developing, technical and scientific skills, and have been grouped into content areas: Organizational Skills Ability to lead and organize projects and teams Ability to ”integrate and bridge” within cross disciplinary project teams --- to recognize cultural differences between the disciplines involved and help people from these disciplines to work together effectively Ability to communicate across disciplines with the ability to use terminology / vocabulary that spans computer science, biology, medicine, clinical healthcare, and statistical analysis) Project Management capability, from initial definition through the project life Ability to effectively communicate and present plans, research results and other relevant information to diverse groups Value Systems/Ethics Understanding of patient-centric thinking / safety and service Ability to design and implement research Ability to understand and comply with privacy and security policy and practice Problem Solving Skills Ability to approach problems conceptually, using appropriate models and abstractions Implementation Authorization - Unique Program - Page 8 Ability to recognize practical considerations and opportunities available in the application domain that will lead to effective solutions. Ability to perform workflow analysis in project design Demonstrate systems scale approaches to problem solving using interface definition and hierarchical and concurrent module decomposition. Computer Science Skills Introductory level ability in software design and project management Understanding of the core concepts of programming, data structures and algorithms Ability to apply the basic concepts of computability and intractability Fundamental understanding of declarative programming paradigms Demonstrated understanding of cyber-infrastructure and architecture of computing (hardware / software) systems Ability to understand and apply modeling and visualization tools and techniques Health Care Understanding of patient care processes Understanding of healthcare policy, business practices and law Understanding of how data and electronic medical records are collected, analyzed and used Understanding of the definitions and conceptual framework of “evidence based” and “customized “ medicine Understanding of the concepts of individualized/customized health care Biology Working understanding of the fundamentals of molecular biology Working understanding of the fundamentals of functional and/or comparative genomics Probability/Statistics Ability to perform trials, experiments; proper analysis Ability to apply statistics to sampling and data mining These outcomes have been structured into an integrated common BMI MA degree core curriculum, with additional emphasis on analytic and clinical concentrations. B. Provide a plan for assessing intended student outcomes. The intended student outcomes include; developing, technical and scientific skills which will be assessed in coursework; integrative skills which must be demonstrated in a project or internship experience; and people and value skills which are best demonstrated in a clinical, Implementation Authorization - Unique Program - Page 9 interdisciplinary team setting that brings together people with the broad range of backgrounds that comprise this new discipline. Direct assessment of the student learning will be tailored to each skill and competency: For traditional classes, course outcomes will be evaluated by individual and team performance demonstrated in course activities, projects and examinations For clinical skills, such as the Theory of Informatics in Clinical Practice*, performance in exercises and projects and clinical mentor evaluations. (*This course is designed to place students in a clinical setting working in teams.) Final project or thesis. The student will use the project or thesis topic proposal to describe a summative assessment of the program outcomes. Faculty, mentors and the committee will evaluate the project or thesis to assess the ability of the student to demonstrate competencies and integrative capabilities commensurate with the degree. On the other hand, program assessment will be done using periodic surveys (each semester in the early delivery of the program, later annually) of the clinical partners to learn where improvements can be made. Current clinical partners include the Mayo Clinic and Hospital, Barrow Neurological Institute, Banner Health, the Biodesign Institute at ASU, and TGen. The immersive experiences outlined within the curriculum, along with internships and placements at these and other health care and research facilities will provide both opportunities to teach and learn, and a context for assessment of student behavior and output. The success rate of graduates of the program who apply for doctoral programs, job placement, and professional contribution (research and publications where appropriate) will also be monitored and used to measure success and guide future development of the program. Surveys of alumni and of their employers will also be undertaken to assess the long term impact of graduates, and to provide data to inform the evolution of the curriculum and research agenda of the BMI Masters program. Currently projected assessments by outcome include: Organizational Lead and organize projects and Teams – mentor observation, team evaluations, project evaluations, surveys ”Integrate and bridge” within cross disciplinary project teams – mentor observation, team evaluation, project evaluations, surveys, thesis Implementation Authorization - Unique Program - Page 10 Communicate across disciplines – course participation, exams, mentor observation, team evaluation, project evaluations, thesis Project Management – mentor observation, project evaluations, surveys, thesis Value Systems/Ethics Patient-centric thinking / safety and service – course participation, exams, mentor observation, project evaluations Design and implement research - mentor observation, project evaluations, peer reviews, publications/presentations Privacy and security policy and practice - exams, mentor observation, project evaluations Problem Solving Conceptual problem solving - mentor observation, team evaluations, project evaluations Recognize effective solutions within context - course participation, exams, mentor observation, team evaluations, project evaluations, thesis Workflow analysis in project design - course participation, exams, mentor observation, team evaluations, project evaluations Systems scale approaches to problem solving - course participation, exams, mentor observation, team evaluations, project evaluations, thesis Computer Science Software design and project management - course participation, exams, mentor observation, project evaluations, thesis Core concepts of programming, data structures and algorithms exams, mentor observation, team evaluations, project evaluations, thesis Apply the basic concepts of computability and intractability - exams, mentor observation, team evaluations, project evaluations, thesis Understanding declarative programming paradigms - exams, mentor observation, team evaluations, project evaluations, thesis Understanding cyber-infrastructure and systems architecture - course participation, exams, mentor observation, team evaluations, project evaluations, thesis Understand and apply modeling and visualization tools and techniques- course participation, exams, mentor observation, project evaluations, thesis Health Care Implementation Authorization - Unique Program - Page 11 Understanding patient care processes - course participation, exams, mentor observation, Understanding healthcare policy, business practices and law - course participation, exams, mentor observation, thesis Understanding data and electronic medical records - course participation, exams, mentor observation, team evaluations, project evaluations, thesis Understanding “evidence based” and “customized “ medicine course participation, exams, mentor observation, thesis Understanding individualized/customized health care - course participation, exams, mentor observation, thesis Biology Working understanding of the fundamentals of molecular biology course participation, exams, mentor observation, team evaluations, project evaluations Working understanding of the fundamentals of functional and/or comparative genomics - course participation, exams, mentor observation, team evaluations, project evaluations Probability/Statistics Perform trials, experiments; proper analysis - course participation, exams, mentor observation, team evaluations, project evaluations, thesis Apply statistics to sampling and data mining - course participation, exams, mentor observation, team evaluations, project evaluations, thesis III. STATE'S NEED FOR THE PROGRAM A. HOW DOES THIS PROGRAM FULFILL THE NEEDS OF THE STATE OF ARIZONA AND THE REGION? The M.S. Program being proposed is designed to address two significant needs, and these are represented in the two concentrations proposed for the program: (1) Clinical Concentration: There is a need for professionals with working skills in biomedical informatics to contribute to clinical practice. While the department will also contribute to medical school and nursing programs preparing the next generation of professionals, at the same time it must also educate professionals coming from other disciplines to work in the informatics side of the healthcare industry. Moreover, there is significant demand for such a program that will provide the continuing education needed by those already practicing but in need of more advanced training in biomedical informatics. Implementation Authorization - Unique Program - Page 12 (2) Analytical Concentration: There is a need for scientists and engineers to advance research and development in health information systems, medical imaging, genome analysis, and the modeling of biological systems. Graduates from this concentration will have the ability to assemble and perform more sophisticated analysis of mountains of previously unstudied information, developed more sophisticated techniques for personalized medical care, and use simulations to perform experiments that shorten the time to make and validate new discoveries in human care. Graduates will work for organizations like TGEN, pharmaceutical companies, and in the public health sector. The hallmark of this program, however, is its emphasis in integrating theory and practice. It is designed to build team relationships between those with deep scientific understanding in computing, mathematics, biosciences AND the doctors, nurses, and technicians to put discovery to work in providing enhanced care of real people. The goal is to promote more rapid transition of new knowledge into use, and will also promote the ”use inspired” research that can have an immediate impact on individual health and quality of life, and on our communities. Recent reports by the Arizona Department of Commerce and the Battelle Technology Partnership Practice cite the need for increased capacity in bioscience to respond to need and foster economic development in Arizona. Nearly all other Western states (notably California, New Mexico, Oregon, Texas, Utah, and Washington) have at least one strong biomedical informatics department. These academic departments play vital support roles to health care professionals, scientists and the bioscience industry in realizing the promise of the genomic revolution. Considering President Bush’s call for a national health information technology infrastructure, electronic medical records, and interoperability among healthcare providers within the next decade, there will be an even greater need among hospitals, health care providers, and bioscience businesses for information technology scientists and professionals, and for medical providers skilled in biomedical informatics. Moreover, with the prospect of eleven new hospitals being built in the Phoenix area alone, Governor’s electronic medical record initiative, and the emerging regional bioscience industry the need for BMI expertise in Arizona could not be greater. These initiatives specifically require the kind of preparation in biomedical informatics that this program is being designed to provide. The proposed M.S. program is the first step by the Department of Biomedical Informatics at Arizona State University toward producing the kind of graduates necessary to yield the benefits to the local and regional economy for which it was created. After the faculty, curriculum, and research agendas are in place for the Masters, we plan to develop and implement a Ph.D. program to address the need for advanced educational opportunities and research collaborations. A recent industry survey found that the market for bioinformatics Implementation Authorization - Unique Program - Page 13 is estimated to be as high as $37 billion in 2006. Those companies will employ workers, creating jobs for Arizonans. A recent Battelle analysis found that university research is having a significant impact on Bioscience in Arizona, giving rise to 11 bioscience companies in 2004, up from 2 on 2002 and 6 in 2003. Biomedical informatics tools and applications developed in Arizona by university researchers and graduates of this program are necessary to foster development of new companies in Arizona. Bioscience jobs in Arizona have grown 11.9% since 2000, to 73,433 jobs in 2004. The Bioindustry in Greater Phoenix already employs nearly 10,000 people in over 550 firms, a growth of over 335% since 1990. Bioindustry jobs generate high wages, which have grown over 50 percent to $50,086 per worker more than $15,000 above the Greater Metropolitan Phoenix average. The M.S. Program in Biomedical Informatics will play a key role in providing the biomedical informatics knowledge essential to prepare new clinicians, scientists and researchers for jobs in these industries, and in continuing education for the growing health care and bioscience sector of the Arizona economy. The new University of Arizona College of Medicine, Phoenix Program will depend on content developed for the biomedical Informatics curriculum, and the proximity of BMI researchers on the Phoenix Biomedical Campus of the Arizona State University System (PBCAUS). Fluency in with information technology in the medical arena will be essential under President Bush’s plan to establish a national health information technology infrastructure. Furthermore, the medical school has the potential to become a leader in medical education by training a new type of physician who is participate in and lead teams utilizing and developing information technology. Graduates of the MS Program at ASU will contribute to the new “ecosystem” necessary for this new kind of medical practice to thrive. An informatics-based curriculum has implications for customization of diagnosis and treatment, and improved patient safety. For example, students can practice surgery using computer simulations before attempting risky procedures on live patients. B. IS THERE SUFFICIENT STUDENT DEMAND FOR THE PROGRAM? The MS Program in Biomedical Informatics at ASU will be attractive to students coming from a broad range of disciplines including Computer Science, Biological Sciences, Computational Biosciences, Healthcare, Statistics and Public Health Management. Because the program has a wide appeal and graduates will be in high demand in the job market, it is anticipated that student demand will be sufficient to meet the goals set forth in this document. Implementation Authorization - Unique Program - Page 14 1. What is the anticipated student enrollment for this program? 5-YEAR PROJECTED ANNUAL ENROLLMENT 1st yr. 2nd yr. 3rd yr. 4th yr. 5th yr. No. Student 10 10 20 20 25 Majors 2. What is the local, regional and national need for this program? Provide evidence of the need for this program. Include an assessment of the employment opportunities for graduates of the program during the next three years. The field of bioinformatics has expanded in recent years to become one of the fastest-growing professions in the nation. It is estimated that over 20,000 new positions for people with bioinformatics degrees will open by the end of 2005, with even more opportunities for those who receive master’s and graduate degrees. Salaries for those with bioinformatics training are high, ranging from $40,000 for those with a bachelor’s degree to over $100,000 for those with a doctoral degree. According to the trade press, biotech and pharmaceutical companies will soon expect the persons they employ to have computer expertise as well as expertise in the biological/medical/clinical sciences. Competition for these individuals will be fierce, and if Arizona can not produce sufficient graduates with these capabilities; the state will not be a competitive location for biomedical industries to relocate. The success of the program will help determine the fraction of the 20,000 new positions being placed in Arizona. Based on interviews with health care providers and biomedical research facilities, we identified a local need for individuals with both M.S. and Ph.D. level bioinformatics training. Because of the rapid expansion of the field locally, regionally and nationally, graduates from the BMI program will be in high demand both in clinical and research settings in the foreseeable future. 3. Beginning with the first year in which degrees will be awarded, what is the anticipated number of degrees that will be awarded each year for the first five years? PROJECTED DEGREES AWARDED ANNUALLY 1st Year 2nd Year 3rd Year 4th Year 5th Year 8 8 17 17 22 No. Degrees (This projection is based upon an anticipated initial attrition rate of 20%, dropping to 10% as the program matures.) Implementation Authorization - Unique Program - Page 15 IV. APPROPRIATENESS FOR THE UNIVERSITY -- Explain how the proposed program is consistent with the University mission and strategic direction statements of the university and why the university is the most appropriate location within the Arizona University System for the program. In the August 4, 2004 Memorandum of Understanding Regarding the Expansion of Medical Education and Research in Phoenix, the Arizona Board of Regents established the Phoenix Biomedical Campus of the Arizona State University System (PBCAUS) and charged Arizona State University with developing a Department of Biomedical Informatics. In December 2005 the formation of the Department was approved. The development of the Department of Biomedical Informatics has involved the University of Arizona, ASU colleges of Liberal Arts and Sciences, Business, and Engineering, research entities including the BioDesign Institute and Translational Genomics Research Institute (TGen), and clinical partners including, Banner Health, Barrow Neurological Institute, and the Mayo Clinic. The resulting plans for the Department of Biomedical Informatics conform to the thirteen principles ABOR set forth in the MOU to “advance our university system and our two research extensive universities to the level of national prominence in biomedical teaching and research.” The proposed MS Program in Biomedical Informatics at ASU is the first of several programs being developed by the new department to fulfill the mission for which it was created. Over the next several months following proposals will be submitted for a certificate program drawing on these same courses, and a Ph.D. program that builds on the Analytical Concentration proposed in this MS Program. V. EXISTING PROGRAMS AT OTHER CAMPUSES A. EXISTING PROGRAMS IN ARIZONA 1. For a unique (non-Duplicative) program, provide a statement to the effect that there are no existing programs at other Arizona public universities that duplicate the proposed program. The office of Institutional Analysis reports there are no existing programs at Arizona Public universities using the CIP code for Bioinformatics (26.1103). 2. Other Institutions No programs in Biomedical Informatics at the Master’s level are currently offered by private institutions in the state of Arizona. Implementation Authorization - Unique Program - Page 16 B. PROGRAMS OFFERED IN OTHER WICHE STATES 1. 1 2 3 4 5 VI. Identify WICHE institutions that currently offer this program. PROGRAMS OFFERED IN OTHER WICHE STATES NCA Program WICHE Accreditation? Accreditation? PROGRAM INSTITUTION & ( Y or N) (Y or N) LOCATON Medical Informatics, Stanford University - CA No No Dept. of Medicine Dept. of Medical Oregon Health and No No Informatics and Clinical Science University - OR Epidemiology, School of Medicine Dept. of Medical University of Utah - UT No No Informatics, School of Medicine Medical Informatics, UC University of California No No Davis Health System Health Systems – UC Davis - CA Masters in Bioscience Keck Graduate Institute No No Program – University of Southern California EXPECTED FACULTY AND RESOURCE REQUIREMENTS A. FACULTY 1. Current Faculty Core Faculty Sethuraman (Panch) Panchanathan, Ph.D. Interim Director – Biomedical Informatics Chair of Computer Science and Engineering Director, Institute for Computing and Information Sciences and Engineering (InCISE) Director, Center for Cognitive Ubiquitous Computing (CUbiC) Shu-Chuan (Grace) Chen, Ph.D. Assistant Professor – Biomedical Informatics / Mathematics and Statistics, Email: scchen@math.la.asu.edu Shahram (Shez) Partovi, M.D. Clinical Professor – Biomedical Informatics Director of Medical Informatics – Barrow Neurological Institute Email: spartovi@partovi.net Howard Silverman M.D., M.S. Clinical Professor – Biomedical Informatics Email: howards@email.arizona.edu Affiliate Faculty Implementation Authorization - Unique Program - Page 17 Metin Akay, Ph.D. Professor of Bioengineering Harrington Department of Bioengineering Chitta Baral, Ph.D. Professor – Computer Science and Engineering Mike Bittner, Ph.D. Director and Senior Investigator – Molecular Diagnostics & Target Validation Division – TGen Carlos Castillo-Chavez, Ph.D. Professor – Mathematics and Statistics Gerald Farin, Ph.D. Professor – Computer Science and Engineering Anne Gelb, Ph.D. Assistant Professor – Mathematics and Statistics Sandeep Gupta, Ph.D. Associate Professor – Computer Science and Engineering David Hrabe, Ph.D. R.N. College of Nursing Director – Academy for Continuing Education Co-Director – Nurse Educator Program William Johnson, Ph.D. Professor – School of Health Management and Policy Director – Center for Health Information and Research Stephen Johnston, Ph.D. Director – Center for Innovations in Medicine Email: Stephen.johnston@asu.edu Seungchan Kim, Ph.D. Assistant Professor – Computer Science and Engineering Head Investigator – Genomic Signal and Information Processing Unit Molecular Diagnostics & Target Validation Division – TGen Bradford Kirkman-Liff, DrPH Professor of Health Policy and Biotechnology – School of Health Management and Policy Email: Bradford.Kirkman.Liff@asu.edu Sudhir Kumar, Ph.D. Associate Professor – School of Life Sciences Director – Center for Evolutionary Functional Genomics – The Biodesign Institute Rosemary Renaut, Ph.D. Director – Computational Biosciences Email: renaut@asu.edu Implementation Authorization - Unique Program - Page 18 Jieping Ye, Ph.D. Assistant Professor – Computer Science and Engineering Email: jieping.ye@asu.edu Keith Frey, M.D. Medical Director (CMIO), Information Technology, Mayo Clinic Arizona, and Associate Professor of Family Medicine – Mayo Clinic College of Medicine 2. Additional Faculty In December 2005 ABOR established the Biomedical Informatics department with the following hiring plan: PROJECTED FACULTY HIRING Year Total Lines Core BMI Faculty Joint Faculty Affiliates Total Faculty FY06 1.5 -4 12 16 FY07 4 4 -14 20 FY08 8 6 4 14 24 Faculty searches are far advanced toward hiring the four core BMI faculty shown in the projection for FY07. 3. Current FTE Students and Faculty Currently, there are no FTE students and 1.15 FTE faculty members in the Biomedical Informatics Department (Grace Chen is 0.5 FTE; S. Partovi is 0.25 FTE; and Howard Silverman is 0.40 FTE). This is reflected in the FY06 Projections shown immediately above. 4. Projected FTE Students and Faculty 3-YEAR PROJECTED ANNUAL ENROLLMENT 1st yr. 2nd yr. 3rd yr. No. Student 10 20 40 Majors Implementation Authorization - Unique Program - Page 19 B. LIBRARY 1. Current Relevant Holdings There are four components of the proposed Department of Biomedical Informatics: molecular biology, medical imaging, medicine, and public health. For many years, the ASU Libraries have collected extensively in the areas of molecular biology and public health. The journal collections in these areas are strong; a few titles may have to be added to provide depth and focus to holdings in selected areas. ASU has worked with the University of Arizona to identify collections and resources within their collections to inform collection development planning for the MS Program in Biomedical Informatics at ASU 2. Additional Acquisitions Needed In contrast to molecular biology and public health, because ASU does not have a medical school, the Libraries’ medical collection has not been developed to support clinical medicine and diagnosis. Similarly, the ASU Libraries have not traditionally collected in the area of medical imaging. These two areas, medicine and medical imaging, will have to be developed to support the BMI faculty and new curricula. And finally, ASU does not license an international patent database. Access to an international patent database will be needed to support basic research efforts. (See Appendix A for an itemization of needed library acquisitions). C. PHYSICAL FACILITIES AND EQUIPMENT 1. Existing Physical Facilities -- Assess the adequacy of the existing physical facilities and equipment available to the proposed program. Include special classrooms, laboratories, physical equipment, computer facilities, etc. The Department of Biomedical Informatics will be primarily housed in the Bank of America building at the Brickyard on Mill (Tempe campus, 660 S. Mill) and the Arizona Biomedical Collaborative Building I, currently under construction in downtown Phoenix. In addition, a number of joint hires will be located in existing institutes and collaborating departments on campus. The Arizona Biomedical Collaborative will be located on the Phoenix Biomedical Campus of the Arizona State University System (PBCAUS), next to the Translational Genomics Research Institute building. The Department will occupy approximately 27,000 square feet in the Arizona Biomedical Collaborative. The anticipated move date is Spring of 2007. This space will consist primarily of faculty labs and offices, several conference rooms, and minimal administrative space. Implementation Authorization - Unique Program - Page 20 Funding has been provided for Arizona Biomedical Collaborative Building I through Laws 2003, Chapter 267 - HB 2529 (university research infrastructure financing). Planning staff are working with the Capital Programs Management Group to design a space suitable for biomedical informatics research. 2. Additional Facilities Required or Anticipated -- Describe physical facilities and equipment that will be required or are anticipated during the next three years for the proposed program. It is anticipated that classroom, student computing space and student lab space will be available at other locations on Phoenix Bioscience Campus. D. OTHER SUPPORT 1. Other Support Now Available Existing clerical and staff positions in the Department of Computer Science and Engineering will support development of the Department of Biomedical Informatics. 2. Other Support Needed, Next Three Years ANTICIPATED NEW POSITIONS: STAFF LINES Position FY06 FY07 FY 08* Associate Director 1 Accountant, Sr. .25 1 Office Specialist, Sr. 1 1 Academic Advisor 1 Systems Admin/Tech Support 1 1 Grantwriter/coordinator 1 Total Additional Staff Lines 2.25 3 3 Note: In FY 2008, the Department will become a split department with approximately half the faculty moving to the Arizona Biomedical Collaborative Building I. As a result, a second Office Specialist Sr. and second Admin Systems Specialist will be hired. VII. FINANCING A. SUPPORTING FUNDS FROM OUTSIDE SOURCES A budget of $1 million has been provided to establish the Department of Biomedical Informatics through Laws 2005, Chapter 330 - SB 1517 (higher education; budget). B. NEW ACADEMIC DEGREE PROGRAM BUDGET PROJECTIONS FORM -- Complete the appropriate budget form, available at http://www2.nau.edu/academicadmin/UCCForms.htm describing the current departmental budget and estimating additional costs for the first three years Implementation Authorization - Unique Program - Page 21 of operation for the proposed program. Please note that these costs for each year are incremental costs, not cumulative costs. The budget request provided in Sections III,4 and III.5 of the Request for Establishment of the Department of Biomedical Informatics, approved by the Arizona Board of Regents in December 2005 addresses the support required for delivery of this program. No additional funding is requested. Implementation Authorization - Unique Program - Page 22 Current Departmental Budget State Faculty 100% Director 20% Interim Director 100% Professor 100% Professor 100% Professor 100% Professor 100% Professor 100% Professor 100% Professor 100% Professor 100% Associate Professor 100% Associate Professor 100% Associate Professor 100% Associate Professor 50% Associate Professor 50% Associate Professor 100% Assistant Professor 100% Assistant Professor 100% Assistant Professor 100% Assistant Professor 50% Assistant Professor 17% Assistant Professor 25% Clinical Professor 40% Clinical Professor 100% Assist. Research Professor 100% (3) Postdocs 50% Associate Director 100% Accountant 3% Technical Supp Analyst Sr. 100% Technical Supp Analyst Sr. 100% Academic Advisor 100% Administrative Associate 0 38743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53556 10124 50000 33333 25000 0 45000 0 1962 0 0 18000 Year 1 - Incremental State Year 2 - Incremental State Year 3 - Incremental State 0 38743 0 0 0 0 0 0 0 0 125000 0 0 0 62500 0 100000 100000 0 0 0 0 0 0 25000 135000 45000 0 0 65000 0 18000 200000 0 0 150000 150000 150000 150000 0 0 0 0 125000 0 0 0 0 0 0 100000 0 0 0 0 0 0 0 0 0 0 0 40000 0 0 0 150000 0 0 0 0 150000 150000 150000 0 0 125000 125000 0 62500 0 0 100000 0 0 0 0 0 0 0 50000 0 0 0 0 Implementation Authorization - Unique Program - Page 23 5% Office Specialist Sr. 10% Administrative Assistant 50% (2) Graduate Assist/Assoc 50% (6)Teaching Assist/Assoc 50% (3) Student Worker ERE Subtotal Personal Services In-State Travel Out-State Travel Professional & Outside Services Other Operating Expenses Subtotal Other Operating Expenses Total PS and OOE One-Time Expenditures * Construction/Renovation Describe: * Equipment Replacement New Computer * Library Resources Total One-Time Expenditures Total Incremental Budget $ $ $ Less one-time expenditures from prior year Total Yearly Budget Source of Funding State Funds - New $ New Department 1507 2762 23500 0 0 303487 117900 421,387 1000 6000 20000 220000 563613 985,000 $ $ 0 0 0 70500 10000 794743 945744.17 1,740,487 1000 1000 5000 7513 14513 1,755,000 $ $ 0 0 0 35000 20000 1120000 1332800 2,452,800 1000 1000 5000 95200 102200 2,555,000 $ $ 0 0 0 0 0 1062500 1264375 2,326,875 10000 10000 10000 468125 498125 2,825,000 0 50000 50000 60000 0 0 15000 0 15000 1,000,000 0 150000 0 20000 25000 245000 2,000,000 350000 0 20000 25000 445000 3,000,000 150000 400000 30000 35000 675000 3,500,000 1,000,000 $ $ 1,000,000 $ 1,000,000 $ $ 1,000,000 $ 2,000,000 $ $ 2,000,000 $ 1,500,000 Implementation Authorization - Unique Program - Page 24 VIII. OTHER RELEVANT INFORMATION This proposal is the first activity implementing curriculum as an outcome of the establishment of the Department of Biomedical Informatics, approved by the Arizona Board of Regents in December 2005. The coursework proposed for this program will also be used to deliver a graduate concentration to be used by several departments as a component of their M.S. programs. The materials for these courses will also be used in the development of a collection of smaller modules that can be used in online delivery of material, both for this program, the concentrations (where the unit modules may be packaged as part of other courses) and in supporting informatics instruction in the Phoenix medical school program of the University of Arizona which is typically delivered in a format and schedule different from typical three unit courses, and for continuing education and professional development. Implementation Authorization - Unique Program - Page 25 Appendix A – Itemization of Library Acquisitions Needed The proposed library acquisitions have been prepared by the ASU libraries, in consultation with the University of Arizona Medical School and U of A libraries with input from rour private and public clinical partners. Included are a combination of print and electronic resources that would be needed to provide a foundation for teaching and research in Biomedical Informatics at the Masters level. Because biomedical informatics is a dynamic field requiring in-depth “niche” collection building, the program budget includes funding for a librarian that can focus the efforts to build, develop, and maintain a first-rate biomedical informatics collection at ASU, and provide and coordinate library services to the faculty, students and staff. Biomedical Informatics Library Budget (estimated) Year one: $100,000 (collections-- electronic journals, databases and patents) $60,000 plus benefits (librarian) Year two: $160,000 ($50,000 for new materials; $110,000 to maintain resources licensed for use in year one plus 10% inflation factor) $65,000 plus benefits (librarian) Year three: $226,000 collections ($50,000 for new materials; $160,000 plus 10% inflation to maintain resources licensed for use in years one and two) $70,000 plus benefits (librarian) Journal Subscriptions We compiled a list of resources based on where faculty in Biomedical Informatics from Columbia, Stanford, and Vanderbilt published in the past five to ten years. We also listed journals identified as “medical informatics” and “computer science – interdisciplinary applications” from the Web of Science index. We then checked to determine whether ASU has a current subscription to each of these titles. Attachment One (sheet 2) lists the journals that the ASU Libraries do not currently subscribe. Subscriptions total to $35,000. Monographs and Memberships We used the same procedure as described above, but noted the monographs and association memberships in Bioinformatics. Attachment Two lists the key memberships and selected monographs that the ASU Libraries do not own. These titles total to $8,000. International Patents Currently, three patent companies offer large-scale searching and web analysis of international patents: Derwent, Delphion, and Patent Café. Initial quotes for these products for Arizona State University range from $32,000 to $78,000 annually. Implementation Authorization - Unique Program - Page 26 Table 1 - Journal Subscriptions Required for Library Title ISSN 2003 Impact Immediacy 2003 Cited ASU Total Factor Index Articles Half Has ( Cites Life N=no) ACAD EMERG MED 10696563 10880224 15301567 03044602 AM J MANAG CARE AMBUL PEDIATR ANN ACAD MED SINGAP Publisher 2046 1.844 0.47 185 4.1 N 853 0.909 0.412 85 3.9 N Hanley & Belfus, Inc. Ascend Media 195 1.458 0.229 48 2.1 N Allen Press Inc. 768 0.375 0.308 133 6.5 N Academy of Medicine Singapore Adis International Ltd. (New Zeland) 236 11755636 ARCH COMPUT METHOD E 11343060 ARCH INTERN MED 0003- 25669 9926 0003- 5994 9985 126 0.867 0 2 6.8 N Intl Ctr Numer Methods Engineering Amer Med Assoc 6.758 1.697 284 6.7 N 1.281 0.288 264 >10.0 N College of Amer Pathologists 14621355 N Cadernos de Saude de Publica 0102311X N Can Journal of Public Health 00084263 N European Bioinformatics Institute Escola Nacional de Saúde Pública (Brazil) Canadian Public Health Association CANCER RES 0008- 103564 5472 8.649 0.935 1289 6.1 N Amer Assoc for Cancer Research CLIN CHEM 0009- 16368 9147 1063158 293X 5.538 1.548 188 7.9 N Academic Press 0.321 0 27 6 N Sage Science (UK) 00928615 434 0.457 10939946 Healthcare Informatics, 14604582 Journal of Medicine and 0360Philosophy 5310 2804 HUM PATHOL 9204 3.685 0.263 198 8 N WB Saunders 3646 1.951 0.59 156 6.2 N Slack, Inc. Bioinformer, The CONCURRENT ENGRES A DRUG INF J Frontiers in Bioscience Infection Control and Hospital Epidemiology 00468177 0899823X 0951192X 62 604 285 426 242 - 230 145 1,909 5,694 1,097 3.603 0.146 0.629 41 275 4.8 2.9 N N Drug Information Association N Frontiers in Bioscience Sage Publications N Taylor & Francis 259 2,294 465 452 560 321 International Journal of 1744Bioinformatics Research 5485 and Applications INT J COMP INTEG M 261 201 Applied Bioinformatics ARCH PATHOL LAB MED 2005 Cost converted to USD $ Inderscience Publishers 281 0.733 0.037 54 518 5.5 embargo Taylor & Francis 1,856 Implementation Authorization - Unique Program - Page 27 INT J HIGH PERFORM C INT J MOD PHYS C 10943420 01291831 International Journal of Healthcare Technology and Management, 2004 13682156 J CANCER EDUC 08858195 J CLIN ONCOL 0732- 45857 10.864 183X 1.677 0091- 3352 2700 1066- 1154 5277 0884- 3874 8734 0161- 14106 5505 1.945 0.404 136 4.6 0.18 61 2.809 0.888 134 4.899 0.796 245 J ORG COMP ELECT COM 10919392 71 0.419 0.071 14 J VIROL 0022- 70944 538X 5.225 1.124 1416 Joint Commission Journal on Quality and Patient Safety, The 15537250 N Journal of Dentistal Education 00220337 N Journal of Healthcare Information Management, 2000 1099811X N Journal of Medical 1056Education Technologies 2478 N Journal of the American 0002College of Dentists 7979 N Journal of the American 1544Pharmacists Association 3191 N J CLIN PHARMACOL J COMPUT BIOL J GEN INTERN MED J NUCL MED 177 2.311 0.1 30 2.8 N Sage Publ. Ltd. 756 0.75 0.235 85 4.5 N World Sci Publ Co Pte Ltd. N Inderscience Publishers 762 Lawrence Erlbaum Associates, Inc. 276 1,131 271 0.412 643 6.4 N 5 N American Society of Clinical Oncology 5.9 N Sage Science Press 3.5 embargo Mary Ann Liebert, Inc. 6.1 embargo Blackwell Publishing 7.1 N Society of Nuclear Medicine N Lawrence Erlbaum Assoc Inc 5.7 embargo Amer Society for Microbiology Joint Commission Resources, Inc. American Dental Education Association Healthcare Information and Management Systems Society Learning Technology Institute American College of Dentists American Pharmacists Assoc. KNOWL ENG REV 02698889 407 0.825 0.167 6 7.5 N Cambridge University Press MATCH-COMMUN MATH CO 03406253 268 0.639 0.31 42 8.3 N Univ of Kragujevac Serbia/Montenegro 0272989X METHOD INFORM MED 00261270 MLA News, 1980 05415489 MOL CELL 1535PROTEOMICS 9476 1740 1.718 0.146 48 8.2 N 815 1.417 0.524 82 5.4 N Sage Science Press Schattauer GmbH MED DECIS MAKING 1,192 667 593 698 541 366 541 1,044 224 144 79 69 46 98 315 99 388 401 N 693 8.316 0.822 73 1.5 N Medical Library Assoc. American Society for Biochemistry and Molecular Biology, Inc. 56 1,133 Implementation Authorization - Unique Program - Page 28 NEW ENGL J MED Online Journal of Bioinformatics 0028- 152715 34.833 4793 SAR QSAR ENVIRON RES 366 14432250 PHARMACOGENOMICS 14622416 Proceedings of the AMIA 1531605X RADIOLOGY 11.719 447 0033- 35486 8419 1062936X 520 3.506 4.815 1.83 0.58 0.708 0.194 50 465 36 7.1 WESTERN J MED Yearbook of Medical Informatics, 1994 00930415 09434747 Massachusetts Medical Society Pestsearch International Pty. Ltd. (Australia) 2.2 N Future Medicine LTD N American Medical Informatics Association 8.4 N Radiological Society of North America, Inc. 4.4 embargo Taylor & Francis 240 414 1,761 201 92 2,794 Signal Transduction 1525Knowledge Environment 8882 T SOC COMPUT SIMUL 0740I 6797 N N 53 1521 0.353 0.749 0 0 N 9.6 N N American Association for the Advancement of Science Soc Modeling and Simulation Internal (SCS) BMJ Publishing Group Schattauer GmbH 114 201 227 134 TOTAL 35,155 Implementation Authorization - Unique Program - Page 29 Table 2 - Monographs and Memberships Required for Library Publisher/Association Title Date USD Price Estimated Total Cost USD $ 2005 450/yr 450 19972005 125/yr 1,125 19972005 40/yr 320 AMIA American Medical Informatics Association, Institutional Member (includes current journal access) American Medical Informatics Association, Symposium Proceedings American Medical Informatics Association, Yearbook of Medical Informatics IMIA International Medical Informatics Association, Institutional Member 2005 600/yr 600 Imperial College Press Biomathematics Modelling and Simulation 2005 103 103 John Wiley & Sons Bioinformatics and Genome Research 2005 355 355 World Scientific Publishing Advances in Bioinformatics and Its Applications, Proceedings of the International Conferences 19962005 128/yr 1,280 World Scientific Publishing Advances in Scattering and Biomedical Engineering 19982005 95/yr 665 World Scientific Publishing World Scientific Publishing World Scientific Publishing Biocomputing, Proceedings of the Pacific Symposium Biology and Computation: A Physicist's Choice 19952005 varies /yr 1,262 2005 162 162 2005 48 48 2005 198 198 World Scientific Publishing Computational Biology of Cancer Current Trends in Theoretical Computer Science The Challenge of the New Century Vol 1: Algorithms and Complexity Vol 2: Formal Models and Semantics Essential Biotech Investment Guide: How to Invest in the Healthcare Biotechnology and Life Sciences Sector 2002 48 48 World Scientific Publishing Frontiers in Human Genetics Diseases and Technologies 2005 82 82 AMIA AMIA World Scientific Publishing Implementation Authorization - Unique Program - Page 30 World Scientific Publishing World Scientific Publishing World Scientific Publishing World Scientific Publishing Hilbert-Huang Transform and Its Applications, The Information Processing and Living Systems 2005 98 98 2005 96 96 2005 70 70 2002 67 67 2005 78 78 2005 398 398 World Scientific Publishing Information Theory and Evolution Jewels of Stringology Text Algorithms Mathematically Modelling the Electrical Activity of the Heart From Cell to Body Surface and Back Again Medical Imaging Systems Technology A 5-Volume Set (1) Analysis and Computational Methods; (2) Modalities; (3) Methods in General Anatomy; (4) Methods in Diagnosis Optimization; (5) Methods in Cardiovascular and Brain Systems World Scientific Publishing Medical Statistics and Computer Experiments with CD ROM 2005 118 118 World Scientific Publishing World Scientific Publishing Micro Meso Macro Addressing Complex Systems Couplings 2005 86 86 2004 100 100 2005 78 78 2004 62 62 World Scientific Publishing World Scientific Publishing Practical Bioinformatician, The Proceedings of the 3rd AsiaPacific Bioinformatics Conference World Scientific Publishing Selected Topics in Post-Genome Knowledge Discovery TOTAL 7,949