CANCER: PAEDIATRIC AND YOUNG ADULT September 2014 This bulletin is produced every two months and relates to both cancer and the young adult and paediatric oncology, and should be of interest to staff working in this area. Topics covered include symptom management, screening/pathology/staging, psychological and survivorship issues. Many of the following articles are available online via the NHS Scotland Knowledge Network. Please use the links where provided and your NHS Scotland ATHENS password. A complete list of available online journals and registration for ATHENS can be found at www.knowledge.scot.nhs.uk/ If the article you require is not available via the NHS Scotland Knowledge Network and you would like to request a print copy, please submit your request online at www.quest.scot.nhs.uk This bulletin contains a selection of material gathered from a search of the evidence base, and is not intended to be comprehensive. Professional judgment should be exercised when appraising the material. The Library takes no responsibility for the wording, content and accuracy of the information supplied, which has been extracted in good faith from reputable sources. NHSGGC is not responsible for the content of external internet sites. Contents: Communication and Decision Making ……………………………………………………………...2 Prognosis, Risk Factors and Incidence …………………………………………………………….3 Psychological Issues …………………………………………………………………………………6 Screening/Pathology/Staging/Biomarkers …………………………………………………………7 Survivorship Issues and Quality of Life …………………………………………………………….10 Symptom Management ………………………………………………………………………………13 Therapies ………………………………………………………………………………………………17 Working with Paediatric and Young Adult Patients ………………………………………………..21 Compiled by: Lorraine McLeod Assistant Librarian Level 0, Education Suite, Beatson West of Scotland Cancer Centre, 1053, Great Western Road, Glasgow G12 0YN 0141 3017283, lorraine.mcleod@ggc.scot.nhs.uk -1Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Special Journal Issues American Society of Pediatric Hematology/Oncology, ASPHO 2014. Pediatric Blood and Cancer. 61 Suppl 1, May 2014 Adolescent and young adult series. Cancer. 120(15), 2226 - 2281 Bell E, Chen L, Viprey VF, et al. (2014) Meeting report: 3rd neuroblastoma research symposium, Liverpool, 6-7th November, 2013. Pediatric Blood and Cancer. 61(9), 1711-1713 Clinical trial enrollment among adolescents with cancer Pediatrics. 133(Suppl 3) June 2014, S85 –S130 Communication and Decision Making Hord J, Feig S, Crouch G, et al. (2014) Standards for pediatric cancer centers. Pediatrics. 134(2), 410-414 Baggott C, Cooper BA, Marina N, et al. (2014) Symptom assessment in pediatric oncology: How should concordance between children's and parents' reports be evaluated?. Cancer Nursing. 37(4), 252-262 Bally JMG, Holtslander L, Duggleby W, et al. (2014) Understanding parental experiences through their narratives of restitution, chaos, and quest: Improving care for families experiencing childhood cancer. Journal of Family Nursing. 20(3), 287-312 Barling JA, Stevens JA and Davies KM. (2014) The reality of hospitalisation: Stories from family members of their hospital experience for adolescents and young adults living with and dying from cancer. Contemporary Nurse. 46(2), 150-160 Bergstraesser E, Paul M, Rufibach K, et al. (2014) The paediatric palliative screening scale: Further validity testing. Palliative Medicine. 28(6), 530-533 Day S, Hollis R, Challinor J, et al. (2014) Baseline standards for paediatric oncology nursing care in low to middle income countries: Position statement of the SIOP PODC nursing working group. Lancet Oncology. 15(7), 681-682 Farjou G, Sinha R, Dix D, et al. (2014) Understanding the healthcare experiences of teenaged cancer patients and survivors. Child: Care, Health & Development. 40(5), 723-730 Fern LA, Lewandowski JA, Coxon KM, et al. (2014) Available, accessible, aware, appropriate, and acceptable: A strategy to improve participation of teenagers and young adults in cancer trials. The Lancet Oncology. 15(8), e341-350 Fernandes SM, O'Sullivan-Oliveira J, Landzberg MJ, et al. (2014) Transition and transfer of adolescents and young adults with pediatric onset chronic disease: The patient and parent perspective. Journal of Pediatric Rehabilitation Medicine. 7(Transition.), 43-51 Goldfarb M and Casillas J. (2014) Unmet information and support needs in newly diagnosed thyroid cancer: Comparison of adolescents/young adults (AYA) and older patients. Journal of Cancer Survivorship. 8(3), 394-401 Gorman JR, Roberts SC, Dominick SA, et al. (2014) A diversified recruitment approach incorporating social media leads to research participation among young adult-aged female cancer survivors. Journal of Adolescent and Young Adult Oncology. 3(2), 59-65 Hamm MP, Shulhan J, Williams G, et al. (2014) A systematic review of the use and effectiveness of social media in child health. BMC pediatrics. 14 (1), 138 Mascarin M, Truccolo I, Byther E, et al. (2014) Cancer, adolescence, and their peers: "they'll give you a story". Journal of Cancer Education. 29(3), 434-440 Packer RJ. (2014) Parental and physician attitudes toward medulloblastoma treatment. Pediatric Blood and Cancer. 61(7), 1149-1150 -2Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Pagano E, Baldi I, Mosso ML, et al. (2014) The economic burden of caregiving on families of children and adolescents with cancer: A population-based assessment. Pediatric Blood & Cancer. 61(6), 1088-1093 Parker H, Farrell M, Ryder A, et al. (2014) Family-focused children’s end of life care in hospital and at home. Nursing Children & Young People. 26(6), 35-39 Pelletier W, Hinds PS, Alderfer MA, et al. (2014) Themes reported by families as important when proceeding with pediatric hematopoietic stem cell transplantation. Pediatric Blood and Cancer. 61(9), 1625-1631 Rosenberg A, R., Dussel V, Orellana L, et al. (2014) What's missing in missing data? omissions in survey responses among parents of children with advanced cancer. Journal of Palliative Medicine. 17(8), 953-956 Schepers SA, Engelen VE, Haverman L, et al. (2014) Patient reported outcomes in pediatric oncology practice: Suggestions for future usage by parents and pediatric oncologists. Pediatric Blood and Cancer. 61(9), 1707-1710 Smith H. (2014) Giving hope to families in palliative care and implications for practice. Nursing Children & Young People. 26(5), 21-25 Smith MA, Altekruse SF, Adamson PC, et al. (2014) Declining childhood and adolescent cancer mortality. Cancer. 120(16), 2497-2506, Editorial 2388-2391 Stoneham SJ, Hale JP, Rodriguez-Galindo C, et al. (2014) Adolescents and young adults with a "rare" cancer: Getting past semantics to optimal care for patients with germ cell tumors. Oncologist. 19(7), 689-692 Valdez-Martinez E, Noyes J and Bedolla M. (2014) When to stop? decision-making when children's cancer treatment is no longer curative: A mixed-method systematic review. BMC pediatrics. 14 (1), 124 Vassal G, Fitzgerald E, Schrappe M, et al. (2014) Challenges for children and adolescents with cancer in Europe: The SIOP-europe agenda. Pediatric Blood and Cancer. 61(9), 1551-1557 Weaver MS and Hendricks M. (2014) A president who prioritized children: Applying Mandela's memory toward a global pediatric oncology future. Pediatric Blood & Cancer. 61(6), 1145-1146 Wiener L, Sweeney C, Baird K, et al. (2014) What do parents want to know when considering autopsy for their child with cancer?. Journal of Pediatric Hematology/Oncology. 36(6), 464-470 Wolfe J, Orellana L, Cook EF, et al. (2014) Improving the care of children with advanced cancer by using an electronic patient-reported feedback intervention: Results from the PediQUEST randomized controlled trial. Journal of Clinical Oncology. 32(11), 1119-1126 Prognosis, Risk Factors and Incidence Ai WZ, Keegan TH, Press DJ, et al. (2014) Outcomes after diagnosis of mycosis fungoides and sezary syndrome before 30 years of age: A population-based study. JAMA Dermatology. 150(7), 709-715 Aplenc R. Zhang MJ. Sung L. Zhu X. Ho VT. Cooke K. Dvorak C. Hale G. Isola LM. Lazarus HM. McCarthy PL. Olsson R. Pulsipher M. Pasquini MC. Bunin N. Regimen-Related Toxicity Working Committee,Center for International Blood and Marrow Transplant Research. (2014) Effect of body mass in children with hematologic malignancies undergoing allogeneic bone marrow transplantation. Blood. 123(22), 3504-3511 Biswas B, Rastogi S, Khan SA, et al. (2014) Outcomes and prognostic factors for Ewing-family tumors of the extremities. Journal of Bone & Joint Surgery - American Volume. 96(10), 841-849 Bunch KJ, Keegan TJ, Swanson J, et al. (2014) Residential distance at birth from overhead high-voltage powerlines: Childhood cancer risk in Britain 1962-2008. British Journal of -3Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Cancer. 110(5), 1402-1408 Burd L, Peterson L and Kobrinsky N. (2014) Fetal alcohol spectrum disorders and childhood cancer: A concise review of case reports and future research considerations. Pediatric Blood & Cancer. 61(5), 768-770 Cario G, Rhein P, Mitlohner R, et al. (2014) High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol. Haematologica. 99(1), 103-110 Cheng JS, Ivan ME, Stapleton CJ, et al. (2014) Intraoperative changes in transcranial motor evoked potentials and somatosensory evoked potentials predicting outcome in children with intramedullary spinal cord tumors. Journal of Neurosurgery.Pediatrics. 13(6), 591-599 Ciambotti B, Mussolin L, D'Amore ESG, et al. (2014) Monoallelic mutations of the perforin gene may represent a predisposing factor to childhood anaplastic large cell lymphoma. Journal of Pediatric Hematology/Oncology. 36(6), e359-e365 Desandes E, Guissou S, Chastagner P, et al. (2014) Incidence and survival of children with central nervous system primitive tumors in the French national registry of childhood solid tumors. Neuro-Oncology. 16(7), 975-983 Gessi M, Von Bueren AO, Treszl A, et al. (2014) MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system. Neuro-Oncology. 16(7), 924-932 Gorlick S, Barkauskas DA, Krailo M, et al. (2014) HER-2 expression is not prognostic in osteosarcoma; a children's oncology group prospective biology study. Pediatric Blood and Cancer. 61(9), 1558-1564 Greenop KR, Miller M, De Klerk NH, et al. (2014) Maternal dietary intake of folate and vitamins B6 and B12 during pregnancy and risk of childhood brain tumors. Nutrition and Cancer. 66(5), 800-809 Huang WY, Muo CH, Lin CY, et al. (2014) Paediatric head CT scan and subsequent risk of malignancy and benign brain tumour: A nation-wide population-based cohort study. British Journal of Cancer. 110(9), 2354-2360 Kawai M, Malone KE, Tang MT, et al. (2014) Active smoking and the risk of estrogen receptorpositive and triple-negative breast cancer among women ages 20 to 44 years. Cancer. 120(7), 1026-1034 Koka A, Saygin C, Uzunaslan D, et al. (2014) A 17-year experience with ALL-BFM protocol in acute lymphoblastic leukemia: Prognostic predictors and interruptions during protocol. Leukemia Research. 38(6), 699-705 Kukreja S, Ambekar S, Sin AH, et al. (2014) Cumulative survival analysis of patients with spinal myxopapillary ependymomas in the first 2 decades of life. Journal of Neurosurgery.Pediatrics. 13(4), 400-407 Linabery AM, Erhardt EB, Fonstad RK, et al. (2014) Infectious, autoimmune and allergic diseases and risk of Hodgkin lymphoma in children and adolescents: A children's oncology group study. International Journal of Cancer. 135(6), 1454-1469 Lu Y, Kham SK, Ariffin H, et al. (2014) Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia. British Journal of Cancer. 110(6), 1673-1680 Meulepas JM, Ronckers CM, Smets AM, et al. (2014) Leukemia and brain tumors among children after radiation exposure from CT scans: Design and methodological opportunities of the Dutch pediatric CT study. European Journal of Epidemiology. 29(4), 293-301 Miyakawa M. (2014) Radiation exposure and the risk of pediatric thyroid cancer. Clinical Pediatric Endocrinology. 23(3), 73-82 -4Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Patterson BC, Chen Y, Sklar CA, et al. (2014) Growth hormone exposure as a risk factor for the development of subsequent neoplasms of the central nervous system: A report from the childhood cancer survivor study. Journal of Clinical Endocrinology & Metabolism. 99(6), 20302037 Richiardi L, Vizzini L, Pastore G, et al. (2014) Lifetime growth and risk of testicular cancer. International Journal of Cancer. 135(3), 695-701 Rufo PA. (2014) Inflammatory bowel disease and neoplasia in children. Digestive Diseases. 32(4), 455-462 Ruperto N and Martini A. (2014) Juvenile idiopathic arthritis and malignancy. Rheumatology (United Kingdom). 53(6) (pp 968-974) Russell LJ, Enshaei A, Jones L, et al. (2014) 1453-1462 IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome. Journal of Clinical Oncology. 32(14), 1453-1462 Saettini F, Conter V, Provenzi M, et al. (2014) Is multifocality a prognostic factor in childhood hepatoblastoma?. Pediatric Blood and Cancer. 61(9), 1593-1597 Sakamoto LH, Andrade RV, Felipe MS, et al. (2014) SMYD2 is highly expressed in pediatric acute lymphoblastic leukemia and constitutes a bad prognostic factor. Leukemia Research. 38(4), 496-502 Shih T-, Wu J, Muo C-, et al. (2014) Association between leukaemia and X-ray in children: A nationwide study. Journal of Paediatrics and Child Health. 50(8), 615-618 Silveira VS, Freire BMR, Borges KS, et al. (2014) Hypoxia-related gene expression profile in childhood acute lymphoblastic leukemia: Prognostic implications. Leukemia and Lymphoma. 55(8), 1751-1757 Valencia-Hipolito A, Hernandez-Atenogenes M, Vega GG, et al. (2014) Expression of KLF4 is a predictive marker for survival in pediatric Burkitt lymphoma. Leukemia and Lymphoma. 55(8), 1806-1814 van der Veer A, Zaliova M, Mottadelli F, et al. (2014) IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL. Blood. 123(11), 1691-1698 Vergamini LB, Frazier AL, Abrantes FL, et al. (2014) Increase in the incidence of differentiated thyroid carcinoma in children, adolescents, and young adults: A population-based study. Journal of Pediatrics. 164(6), 1481-1485 Viprey VF, Gregory WM, Corrias MV, et al. (2014) Neuroblastoma mRNAs predict outcome in children with stage 4 neuroblastoma: A European HR-NBL1/SIOPEN study. Journal of Clinical Oncology. 32(10), 1074-1083 Xing D, Qasem SA, Owusu K, et al. (2014) Changing prognostic factors in osteosarcoma: Analysis of 381 cases from two institutions. Human Pathology. 45(8), 1688-1696 Yuen KC, Koltowska-Haggstrom M, Cook DM, et al. (2014) Primary treatment regimen and diabetes insipidus as predictors of health outcomes in adults with childhood-onset craniopharyngioma. Journal of Clinical Endocrinology & Metabolism. 99(4), 1227-1235 Zhu C, Bassig BA, Shi K, et al. (2014) Different time trends by gender for the incidence of Hodgkin's lymphoma among young adults in the USA: A birth cohort phenomenon. Cancer Causes and Control. 25(8), 923-931 -5Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Psychological Issues Cantrell MA and Posner MA. (2014) Psychological distress between young adult female survivors of childhood cancer and matched female cohorts surveyed in the adolescent health study. Cancer Nursing. 37(4), 271-277 Compas BE, Desjardins L, Vannatta K, et al. (2014) Children and adolescents coping with cancer: Self - and parent reports of coping and anxiety/depression. Health Psychology. 33(8), 853-861 Creswell PD, Wisk LE, Litzelman K, et al. (2014) Parental depressive symptoms and childhood cancer: The importance of financial difficulties. Supportive Care in Cancer. 22(2), 503-511 Daniel LC, Barakat LP, Brumley LD, et al. (2014) Health-related hindrance of personal goals of adolescents with cancer: The role of the interaction of race/ethnicity and income. Journal of Clinical Psychology in Medical Settings. 21(2), 155-164 Drozdowicz LB and Bostwick JM. (2014) Psychiatric adverse effects of pediatric corticosteroid use. Mayo Clinic Proceedings. 89(6), 817-834 Feuz C. (2014) Are current care models meeting the psychosocial needs of adolescent and young adult cancer survivors? A literature review. Journal of Medical Imaging and Radiation Sciences. 45(2), 119-130 Gotte M, Kesting S, Winter C, et al. (2014) Experience of barriers and motivations for physical activities and exercise during treatment of pediatric patients with cancer. Pediatric Blood and Cancer. 61(9), 1632-1637 Hoag J, Kupst MJ, Briere M-, et al. (2014) Feasibility of conducting long-term follow-up of children and infants treated for CNS tumors on the same cooperative group clinical trial protocol. Journal of Clinical Psychology in Medical Settings. 21(2), 136-143 Hocking MC, Kazak AE, Schneider S, et al. (2014) Parent perspectives on family-based psychosocial interventions in pediatric cancer: A mixed-methods approach. Supportive Care in Cancer. 22(5), 1287-1294 Jenholt Nolbris M and Ahlström B, Hedman. (2014) Siblings of children with cancer – their experiences of participating in a person-centered support intervention combining education, learning and reflection: Pre- and post-intervention interviews. European Journal of Oncology Nursing. 18(3), 254-260 Klosky J, L., Krull K, R., Randolph M, E., et al. (2014) BRIEF REPORT. relations between posttraumatic stress and posttraumatic growth in long-term survivors of childhood cancer: A report from the childhood cancer survivor study. Health Psychology. 38(8), 878-882 Labrell F, Kieffer V, Grill J, et al. (2014) Conceptions of time in children treated for malignant cerebellar tumours. Brain Injury. 28(10), 1334-1341 Lai JS, Zelko F, Krull KR, et al. (2014) Parent-reported cognition of children with cancer and its potential clinical usefulness. Quality of Life Research. 23(4), 1049-1058 Lyon M, E., Jacobs S, Briggs L, et al. (2014) A longitudinal, randomized, controlled trial of advance care planning for teens with cancer: Anxiety, depression, quality of life, advance directives, spirituality. Journal of Adolescent Health. 54(6), 710-717 Macartney G, Stacey D, Harrison M, B., et al. (2014) Symptoms, coping, and quality of life in pediatric brain tumor survivors: A qualitative study. Oncology Nursing Forum. 41(4), 390-398 Maurice-Stam H, Scholten L, de Gee EA, et al. (2014) Feasibility of an online cognitive behavioral-based group intervention for adolescents treated for cancer: A pilot study. Journal of Psychosocial Oncology. 32(3), 310-321 Moore L. (2014) Family-centred care conflicts with need for parents to be a 'safe haven'. Nursing Children and Young People. 26(4), 13 -6Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Mu P-, Sheng C-, Tung P-, et al. (2014) The experience of family members of children and adolescents with cancer in its initial stage: A qualitative systematic review protocol. JBI Database of Systematic Reviews and Implementation Reports. 12(2), 35-45 Myers RM, Balsamo L, Lu X, et al. (2014) A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia: A report from the children's oncology group. Cancer. 120(9), 1417-1425 Palmer S, Patterson P and Thompson K. (2014) A national approach to improving adolescent and young adult (AYA) oncology psychosocial care: The development of AYA-specific psychosocial assessment and care tools. Palliative & Supportive Care. 12(3), 183-188 Patterson P, McDonald FEJ and Orchard P. (2014) A new Australian online and phone mental health support service for young people living with cancer. Australasian Psychiatry. 22(2), 165-169 Pavisic J, Chilton J, Walter G, et al. (2014) Childhood cancer in the cinema: How the celluloid mirror reflects psychosocial care. Journal of Pediatric Hematology/Oncology. 36(6), 430-437 Ragsdale JR, Hegner MA, Mueller M, et al. (2014) Identifying religious and/or spiritual perspectives of adolescents and young adults receiving blood and marrow transplants: A prospective qualitative study. Biology of Blood and Marrow Transplantation. 20(8), 1238-1257 Robinson L, Miedema B and Easley J. (2014) Young adult cancer survivors and the challenges of intimacy. Journal of Psychosocial Oncology. 32(4), 447-462 Seitz DCM, Knaevelsrud C, Duran G, et al. (2014) Efficacy of an internet-based cognitivebehavioral intervention for long-term survivors of pediatric cancer: A pilot study. Supportive Care in Cancer. 22(8), 2075-2083 Sveen J, Eilegard A, Steineck G, et al. (2014) They still grieve - A nationwide follow-up of young adults 2-9years after losing a sibling to cancer. Psycho-Oncology. 23(6), 658-664 Tillery R, Long A and Phipps S. (2014) Child perceptions of parental care and overprotection in children with cancer and healthy children. Journal of Clinical Psychology in Medical Settings. 21(2), 165-172 Warris LT, van den Heuvel-Eibrink MM, den Hoed MA, et al. (2014) Does dexamethasone induce more neuropsychological side effects than prednisone in pediatric acute lymphoblastic leukemia? A systematic review. Pediatric Blood & Cancer. 61(7), 1313-1318 Wu L, Chiou S, Sheen J, et al. (2014) Evaluating the acceptability and efficacy of a psychoeducational intervention for coping and symptom management by children with cancer: A randomized controlled study. Journal of Advanced Nursing. 70(7), 1653-1662 Screening/Pathology/Staging/Biomarkers Abdelhalim A, Helmy TE, Harraz AM, et al. (2014) Can computerized tomography accurately stage childhood renal tumors?. Journal of Urology. 192(1), 194-199 Alaqeel AM and Sabbagh AJ. (2014) Pediatric brainstem tumors. classifications, investigations, and growth patterns. Neurosciences. 19(2), 93-99 Atkin KL and Ditchfield MR. (2014) The role of whole-body MRI in pediatric oncology. Journal of Pediatric Hematology/Oncology. 36(5), 342-352 In Reply: 332 Bergthold G, Bandopadhayay P, Bi WL, et al. (2014) Pediatric low-grade gliomas: How modern biology reshapes the clinical field. Biochimica Et Biophysica Acta. 1845(2), 294-307 Bernardini G, Laschi M, Geminiani M, et al. (2014) Proteomics of osteosarcoma. Expert Review of Proteomics. 11(3), 331-343 -7Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Brasme JF, Chalumeau M, Oberlin O, et al. (2014) Time to diagnosis of Ewing tumors in children and adolescents is not associated with metastasis or survival: A prospective multicenter study of 436 patients. Journal of Clinical Oncology. 32(18), 1935-1940 Brix N and Rosthoj S. (2014) Bone marrow involvement is not manifest in the early stages of childhood acute lymphoblastic leukaemia. Danish Medical Journal. 61 (8), 10583091 Brohl AS, Solomon DA, Chang W, et al. (2014) The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation. PLoS Genetics. 10 (7) Chen YH and Gutmann DH. (2014) The molecular and cell biology of pediatric low-grade gliomas. Oncogene. 33(16), 2019-2026 Cools MJ, Al-Holou WN, Stetler WR,Jr, et al. (2014) Filum terminale lipomas: Imaging prevalence, natural history, and conus position. Journal of Neurosurgery.Pediatrics. 13(5), 559567 Eyssartier E, Ang P, Bonnemaison E, et al. (2014) Characteristics of endobronchial primitive tumors in children. Pediatric Pulmonology. 49(6), E121-E125 Farkkila A, Andersson N, Butzow R, et al. (2014) HER2 and GATA4 are new prognostic factors for early-stage ovarian granulosa cell tumor-a long-term follow-up study. Cancer Medicine. 3(3), 526-536 Feldman DR, Iyer G, Van Alstine L, et al. (2014) Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors. Clinical Cancer Research. 20(14), 3712-3720 Fontebasso AM, Papillon-Cavanagh S, Schwartzentruber J, et al. (2014) Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. Nature Genetics. 46(5), 462-466 Friedman DN, Lis E, Sklar CA, et al. (2014) Whole-body magnetic resonance imaging (WBMRI) as surveillance for subsequent malignancies in survivors of hereditary retinoblastoma: A pilot study. Pediatric Blood and Cancer. 61(8), 1440-1444 Gessi M, Moneim YA, Hammes J, et al. (2014) FGFR1 mutations in rosette-forming glioneuronal tumors of the fourth ventricle. Journal of Neuropathology & Experimental Neurology. 73(6), 580-584 Grant FD. (2014) 18F-fluoride PET and PET/CT in children and young adults. PET Clinics. 9(3), 287-297 Hayashi T, Haba R, Kushida Y, et al. (2014) Cytopathologic characteristics and differential diagnostic considerations of osteolytic myxopapillary ependymoma. Diagnostic Cytopathology. 42(9), 778-783 Hung EH, Griffith JF, Ng AW, et al. (2014) Ultrasound of musculoskeletal soft-tissue tumors superficial to the investing fascia. AJR.American Journal of Roentgenology. 202(6), W532-40 Ilivitzki A, Abugazala M, Arkovitz M, et al. (2014) Ultrasound-guided core biopsy as the primary tool for tissue diagnosis in pediatric oncology. Journal of Pediatric Hematology/Oncology. 36(5), 333-336 Jelinic P, Mueller JJ, Olvera N, et al. (2014) Recurrent SMARCA4 mutations in small cell carcinoma of the ovary. Nature Genetics. 46(5), 424-426 Jorgensen A, Young J, Nielsen JE, et al. (2014) Hanging drop cultures of human testis and testis cancer samples: A model used to investigate activin treatment effects in a preserved niche. British Journal of Cancer. 110(10), 2604-2614 Kmetec A and Jeruc J. (2014) Xp 11.2 translocation renal carcinoma in young adults; recently classified distinct subtype. Radiology and Oncology. 48(2), 197-202 -8Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Konialis C, Savola S, Karapanou S, et al. (2014) Routine application of a novel MLPA-based first-line screening test uncovers clinically relevant copy number aberrations in haematological malignancies undetectable by conventional cytogenetics. Hematology. 19(4), 217-224 Kvist K, Clasen-Linde E, Cortes D, et al. (2014) Adult immunohistochemical markers fail to detect intratubular germ cell neoplasia in prepubertal boys with cryptorchidism. Journal of Urology. 191(4), 1084-1089 Li M-, Harel M, Hla T, et al. (2014) Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. Journal of Pediatric Surgery. 49(8), 1286-1291 Lim JY, Bhatia S, Robison LL, et al. (2014) Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia. Cancer. 120(7), 955-962 Liu K, Xie P, Peng W, et al. (2014) Renal carcinomas associated with Xp11.2 translocations/TFE3 gene fusions: Findings on MRI and computed tomography imaging. Journal of Magnetic Resonance Imaging. 40(2), 440-447 Lohmann DJA, Sorensen P, Jorgensen J, et al. (2014) Most central nervous system tumours in children are diagnosed with little delay after admission. Danish Medical Journal. 61 (8) Malkin D. (2014) Surveillance for children at genetic risk for cancer: Are we ready?. Pediatric Blood and Cancer. 61(8), 1337-1338 Martin JW, Chilton-MacNeill S, Koti M, et al. (2014) Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neoadjuvant chemotherapy response in paediatric osteosarcoma. Plos One. 9 (5) Mascaro Cordeiro B, Dias Oliveira I, De Seixas Alves MT, et al. (2014) SHH, WNT, and NOTCH pathways in medulloblastoma: When cancer stem cells maintain self-renewal and differentiation properties. Child's Nervous System. 30(7), 1165-1172 Miettinen M and Lasota J. (2014) Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - A review. 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Plos One. 9 (4) Offenmuller S, Ravindranath Y, Goyette G, et al. (2014) Focused screening of a panel of cancerrelated genetic polymorphisms reveals new susceptibility loci for pediatric acute lymphoblastic leukemia. Pediatric Blood and Cancer. 61(8), 1411-1415 Oliveira JC, Pezuk JA, Brassesco MS, et al. (2014) PLK1 expression and BI 2536 effects in childhood acute lymphoblastic leukemia. Pediatric Blood & Cancer. 61(7), 1227-1231 Park H, Turkalo TK, Nelson K, et al. (2014) Ewing sarcoma EWS protein regulates midzone formation by recruiting aurora B kinase to the midzone. Cell Cycle. 13(15), 2391-2399 -9Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Paul SP, Perrow R and Webster MA. (2014) Brain tumours in children: Reducing time to diagnosis. Emergency Nurse. 22(1), 32-36 Rossi ED, Straccia P, Martini M, et al. 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Adolescent Health, Medicine and Therapeutics. 5 115-125 - 17 Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Eichenauer DA, Boll B and Diehl V. (2014) Pharmacotherapy of Hodgkin lymphoma: Standard approaches and future perspectives. Expert Opinion on Pharmacotherapy. 15(8), 1139-1151 Eichenauer DA and Engert A. (2014) Antibodies and antibody-drug conjugates in the treatment of Hodgkin lymphoma. European Journal of Haematology. 93(1), 1-8 Ervey-Jumper SLH, Garton HJL, Lau D, et al. (2014) Differences in vascular endothelial growth factor receptor expression and correlation with the degree of enhancement in medulloblastoma. Journal of Neurosurgery: Pediatrics. 14(2), 121-128 Fawkner-Corbett DW, Howell L, Pizer BL, et al. (2014) Wilms' tumor - lessons and outcomes - A 25-year single center UK experience. Pediatric Hematology and Oncology. 31(5), 400-408 Fraser C, Brown P, Megason G, et al. (2014) Open-label bendamustine monotherapy for pediatric patients with relapsed or refractory acute leukemia: Efficacy and tolerability. Journal of Pediatric Hematology/Oncology. 36(4), e212-8 Gandemer V, Pochon C, Oger E, et al. (2014) Clinical value of pre-transplant minimal residual disease in childhood lymphoblastic leukaemia: The results of the French minimal residual disease-guided protocol. British Journal of Haematology. 165(3), 392-401 Haddox CL, Han G, Anijar L, et al. (2014) Osteosarcoma in pediatric patients and young adults: A single institution retrospective review of presentation, therapy, and outcome. Sarcoma. Hankinson TC, Palmeri NO, Williams SA, et al. (2014) Patterns of care for craniopharyngioma: Survey of members of the American Association of Neurological Surgeons. Pediatric Neurosurgery. 49(3), 131-136 Hartman LLR, Crawford JR, Makale MT, et al. (2014) Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors. Journal of Pediatric Hematology/Oncology. 36(6), 451-457 Hasle H. (2014) A critical review of which children with acute myeloid leukaemia need stem cell procedures. British Journal of Haematology. 166(1), 23-33 Hodak E, Amitay-Laish I, Feinmesser M, et al. (2014) Juvenile mycosis fungoides: Cutaneous Tcell lymphoma with frequent follicular involvement. Journal of the American Academy of Dermatology. 70(6), 993-1001 Israels T, Bailey S, Verschoor R, et al. (2014) Management of children with Wilms tumor in Africa and Europe; thoughts about costs, priorities and collaboration. Pediatric Hematology and Oncology. 31(5), 395-399 Izraeli S. (2014) Beyond philadelphia: 'ph-like' B cell precursor acute lymphoblastic leukemias - diagnostic challenges and therapeutic promises. Current Opinion in Hematology. 21(4), 289-296 Jeha S, Coustan-Smith E, Pei D, et al. (2014) Impact of tyrosine kinase inhibitors on minimal residual disease and outcome in childhood philadelphia chromosome-positive acute lymphoblastic leukemia. Cancer. 120(10), 1514-1519 Johnson PRV. (2014) Gastroenteropancreatic neuroendocrine (carcinoid) tumors in children. Seminars in Pediatric Surgery. 23(2), 91-95 Karski EE, Dvorak CC, Leung W, et al. (2014) Treatment of hepatoblastoma with high-dose chemotherapy and stem cell rescue: The pediatric blood and marrow transplant consortium experience and review of the literature. Journal of Pediatric Hematology/Oncology. 36(5), 362-368 Kochuparambil ST and Litzow MR. (2014) Novel antibody therapy in acute lymphoblastic leukemia. Current Hematologic Malignancy Reports. 9(2), 165-173 Kutny MA, Gregory J, J, et al. (2014) Treatment of paediatric APL: How does the therapeutic approach differ from adults?. Best Practice and Research: Clinical Haematology. 27(1), 69-78 - 18 Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Lang P, Teltschik HM, Feuchtinger T, et al. (2014) Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia. British Journal of Haematology. 165(5), 688-698 Levinsen M, Taskinen M, Abrahamsson J, et al. (2014) Clinical features and early treatment response of central nervous system involvement in childhood acute lymphoblastic leukemia. Pediatric Blood and Cancer. 61(8), 1416-1421 Li D, Hao SY, Tang J, et al. (2014) Surgical management of pediatric brainstem cavernous malformations. Journal of Neurosurgery.Pediatrics. 13(5), 484-502 Malkan AD, Loh AHP and Sandoval JA. (2014) Minimally invasive surgery in the management of abdominal tumors in children. Journal of Pediatric Surgery. 49(7), 1171-1176 Markovina S, Grigsby PW, Schwarz JK, et al. (2014) Treatment approach, surveillance, and outcome of well-differentiated thyroid cancer in childhood and adolescence. Thyroid. 24(7), 1121-1126 Martiniuk A, Silva M, Amylon M, et al. (2014) Camp programs for children with cancer and their families: Review of research progress over the past decade. Pediatric Blood & Cancer. 61(5), 778-787 Mathew RK, O'kane R, Parslow R, et al. (2014) Comparison of survival between the UK and US after surgery for most common pediatric CNS tumors. Neuro-Oncology. 16(8), 1137-1145 Mihai R. (2014) Rare adrenal tumors in children. Seminars in Pediatric Surgery. 23(2), 71-75 Mihailovic J, Nikoletic K and Srbovan D. (2014) Recurrent disease in juvenile differentiated thyroid carcinoma: Prognostic factors, treatments, and outcomes. Journal of Nuclear Medicine. 55(5), 710-717 Ojha RP and Gurney JG. (2014) Methylenetetrahydrofolate reductase C677T and overall survival in pediatric acute lymphoblastic leukemia: A systematic review. Leukemia & Lymphoma. 55(1), 67-73 Patel SA, Coulter DW, Grovas AC, et al. (2014) Cytosine arabinoside and mitoxantrone followed by second allogeneic transplant for the treatment of children with refractory juvenile myelomonocytic leukemia. Journal of Pediatric Hematology/Oncology. 36(6), 491-494 Percival ME, Hoppe RT and Advani RH. (2014) Bulky mediastinal classical Hodgkin lymphoma in young women. Oncology (Williston Park). 28(3), 253-256 Pollack IF, Jakacki RI, Butterfield LH, et al. (2014) Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas. Journal of Clinical Oncology. 32(19), 2050-2058 Porkholm M, Valanne L, Lonnqvist T, et al. (2014) Radiation therapy and concurrent topotecan followed by maintenance triple anti-angiogenic therapy with thalidomide, etoposide, and celecoxib for pediatric diffuse intrinsic pontine glioma. Pediatric Blood and Cancer. 61(9), 1603-1609 Raetz EA, Morrison D, Romanos-Sirakis E, et al. (2014) A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): A report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium. Journal of Pediatric Hematology/Oncology. 36(6), 458-463 Raikar SS, Halloran DR, Elliot M, et al. (2014) Outcomes of pediatric low-grade gliomas treated with radiation therapy: A single-institution study. Journal of Pediatric Hematology/Oncology. 36(6), e366-e370 Rasper M, Jabar S, Ranft A, et al. (2014) The value of high-dose chemotherapy in patients - 19 Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network with first relapsed Ewing sarcoma. Pediatric Blood and Cancer. 61(8), 1382-1386 Ribera JM, Oriol A, Morgades M, et al. (2014) Treatment of high-risk philadelphia chromosome-negative acute lymphoblastic leukemia in adolescents and adults according to early cytologic response and minimal residual disease after consolidation assessed by flow cytometry: Final results of the PETHEMA ALL-AR-03 trial. Journal of Clinical Oncology. 32(15), 1595-1604 Rose K and Senn S. (2014) Drug development: EU paediatric legislation, the European Medicines Agency and its paediatric committee - adolescents' melanoma as a paradigm. Pharmaceutical Statistics. 13(4), 211-213 Salinas CA, Tsodikov A, Ishak-Howard M, et al. (2014) Prostate cancer in young men: An important clinical entity. Nature Reviews Urology. 11(6), 317-323 Schucht P, Seidel K, Murek M, et al. (2014) Low-threshold monopolar motor mapping for resection of lesions in motor eloquent areas in children and adolescents. Journal of Neurosurgery.Pediatrics. 13(5), 572-578 Schultz KR, Carroll A, Heerema NA, et al. (2014) Long-term follow-up of imatinib in pediatric philadelphia chromosome-positive acute lymphoblastic leukemia: Children's oncology group study AALL0031. Leukemia. 28(7), 1467-1471 Smith MA. (2014) Lessons learned from adult clinical experience to inform evaluations of VEGF pathway inhibitors in children with cancer. Pediatric Blood and Cancer. 61(8), 1497-1505 Smith SE, Waller JC, Bingham IA, et al. (2014) A diffuse intrinsic pontine glioma roadmap: Guiding research toward a cure. Pediatric Blood & Cancer. 61(5), 765-767 Soole F, Maupain C, Defachelles A-, et al. (2014) Synovial sarcoma relapses in children and adolescents: Prognostic factors, treatment, and outcome. Pediatric Blood and Cancer. 61(8), 1387-1393 Stull JW, Brophy J, Sargeant JM, et al. (2014) Knowledge, attitudes, and practices related to pet contact by immunocompromised children with cancer and immunocompetent children with diabetes. Journal of Pediatrics. 165(2), 348-355.e2 Subbiah V. (2014) Prospects and pitfalls of personalizing therapies for sarcomas: From children, adolescents, and young adults to the elderly. Current oncology reports. 16 (9), 401 Sullivan EM, Wilson MW, Billups CA, et al. (2014) Pathologic risk-based adjuvant chemotherapy for unilateral retinoblastoma following enucleation. Journal of Pediatric Hematology/Oncology. 36(6), e335-e340 Taylor RE, Howman AJ, Wheatley K, et al. (2014) Hyperfractionated accelerated radiotherapy (HART) with maintenance chemotherapy for metastatic (M1-3) medulloblastoma - A safety/feasibility study. Radiotherapy and Oncology. 111(1), 41-46 Thorp NJ and Taylor RE. (2014) Management of central nervous system tumours in children Clinical Oncology. 26(7), 438-445 Tsai Y-, Lin P-, Chew K-, et al. (2014) Dermatofibrosarcoma protuberans in children and adolescents: Clinical presentation, histology, treatment, and review of the literature. Journal of Plastic, Reconstructive and Aesthetic Surgery. 67(9), 1222-1229 Turner DC, Navid F, Daw NC, et al. (2014) Population pharmacokinetics of bevacizumab in children with osteosarcoma: Implications for dosing. Clinical Cancer Research. 20(10), 27832792 Vallero SG, Bertin D, Basso ME, et al. (2014) Diffuse intrinsic pontine glioma in children and adolescents: A single-center experience. Child's Nervous System. 30(6), 1061-1066 Weiss B, Widemann BC, Wolters P, et al. (2014) Sirolimus for non-progressive NF1-associated plexiform neurofibromas: An NF clinical trials consortium phase II study. Pediatric Blood & Cancer. 61(6), 982-986 - 20 Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network Widemann BC, Babovic-Vuksanovic D, Dombi E, et al. (2014) Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas. Pediatric Blood and Cancer. 61(9), 1598-1602 Wilhelm M, Dirksen U, Bielack SS, et al. (2014) ENCCAWP17-WP7 consensus paper on teenagers and young adults (TYA) with bone sarcomas. Annals of Oncology. 25(8) (pp 15001505) Zwintscher NP, Azarow KS and Horton JD. (2014) Morbidity and mortality associated with liver resections for primary malignancies in children. Pediatric Surgery International. 30(5), 493497 Working with Paediatric and Young Adult Patients Anonymous (2014) Teenage cancer trust shares 24 years of care experience. Nursing Standard. 28(46), 10-10 Booles V. (2014) Starting out: Student experiences in the real world of nursing. Caring for a scared teenager had an impact on my nursing practice. Nursing Standard. 28(47), 31-31 Depianti J, da Silva LF, da SC, et al. (2014) Nursing perceptions of the benefits of ludicity on care practices for children with cancer: A descriptive study. Online Brazilian Journal of Nursing. 13(2), 154-161 Sprinks J. (2014) Staff urged to consider how cancer therapy affects teens. Nursing Children & Young People. 26(5), 6-6 Stanback R. (2014) Right care for teenagers. Nursing Times. 110(20), 25 Steinbeck K, Towns S and Bennett D. (2014) Adolescent and young adult medicine is a special and specific area of medical practice. Journal of Paediatrics and Child Health. 50(6), 427-431 Zabel-du Bois A, Milker-Zabel S, Bruns F, et al. (2014) Evaluation of time, attendance of medical staff and resources for radiotherapy in pediatric and adolescent patients. The DEGRO-QUIRO trial. Strahlentherapie Und Onkologie. 190(6), 582-590 Please note that the journal articles you are accessing are subject to the terms and conditions imposed by the publisher, so there will be a limit on the number of articles an individual may download or print from a single issue of a journal. You can consult your local NHSGGC library with any queries. If you have any questions regarding this or any other library services please contact Library staff – contact details are at the beginning of the bulletin. Sources used for this bulletin : OVID MEDLINE and MEDLINE in process, EMBASE, CINAHL Journal of Adolescent and Young Adult Oncology Journal of Pediatric Oncology Nursing - 21 Cancer: Paediatric and Young Adult, September 2014 Lorraine McLeod, Assistant Librarian, NHSGGC Library Network