Molecular Biology and Genetics
BIOL 202, Summer Session II, 2015
Class Information:
Lecture: M-F, 9:45-11:15 p.m., Wilson 107
Recitations: Monday, Tuesday and Thursday, Wilson 213
Section 601: 12-12:50 p.m.
Section 602: 1-1:50 p.m.
Website: https://www.unc.edu/sakai/
Instructor:
Dr. Tonya Laakko Train, Ph.D.
Office: Wilson G43
Contact: ttrain@elon.edu
Office Hours: Wed & Fri 11:15-12:15 and by appointment
Recitation Instructor:
Antonio Serrato-Capuchina, gaserrat@email.unc.edu
Course Description: This course will introduce students to the fundamentals of genetics
and molecular biology. We will investigate how genes result in traits, how genetic material is
transmitted and recombined and the biological consequences of major chromosomal
abnormalities. In addition, students will learn the molecular processes of DNA replication,
transcription, translation and gene expression.
Course Goals The successful student will have achieved the following goals upon completion
of this course:
 Will have gained a fundamental understanding of the transmission of genetic material
 Will understand the process and result of recombination of genetic material
 Will know how to determine phenotypic outcomes of single and multiple gene crosses
 Will have a solid understanding of the molecular basis of genetic information and gene
expression
 Will understand the molecular basis and phenotypic outcomes of genetic mutations
 Will be able to relate genetic concepts to real-life situations
 Will understand and know the molecules involved in replication, transcription and
translation of genetic material
Required Text and Website companion:
Sanders and Bowman “Genetic Analysis: An Integrated Approach” plus MasteringGenetics™.
An access code for MasteringGenetics is included with the purchase of a new text. It can also be
purchased separately at www.masteringgenetics.com.
MasteringGenetics Course ID: BIOL202SUMMER15TRAIN
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Additional Requirements:
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Prerequisites are a grade of C or higher in BIOL 101 and CHEM 101 or CHEM 102
Students will be required to utilize Sakai to obtain assignments and other information.
You must be accessible at the email address listed in Sakai.
You must bring a calculator (cell phones may not be used as calculators) to each exam.
You are responsible for checking Sakai regularly for announcements and updates.
Course Policies:
 Attendance- It is to your benefit to attend each lecture and recitation session. This
course will move quickly and cover a lot of material. If you fall behind, it will be a
significant disadvantage. With that said, there is no formal penalty for absences but
attendance will be documented. Absences from recitation will result in a forfeit of any
points earned during that session (including homework problems).
 Missed Exams- You may NOT make-up missed exams. The rare exception to this
policy is in the case of a University-approved absence or a documented emergency.
 Integrity- Lying, cheating or stealing will not be tolerated. During examinations, the
only electronic device that might be allowed is a calculator. All other electronics must be
stowed. During class, texting, twittering, Facebooking… is disrespectful, please refrain
from e-communicating.
You are bound by the University Honor Code. The following statement was provided by
the office of the Vice Chancellor and Provost and applies and is the policy for this course:
"The Honor Code is in effect in this class and all others at the University. I am
committed to treating Honor Code violations seriously and urge all students to
become familiar with its terms (http://instrument.unc.edu). If you have questions, it is
your responsibility to ask me about the Code's application. All exams, written work,
and other projects must be submitted with a statement that you have complied with
the requirements of the Honor Code on all aspects of the submitted work.”
Special Needs: Please contact an instructor as soon as possible to discuss any documented
special needs. We will do everything possible to make accommodations for your success in this
class. The website for the Academic Success Program for Students with Learning Disabilities
can be found at http://www.unc.edu/depts/lds/.
Grading:
Point distribution
200 points
200 points
50 points
50 points
2 Semester exams (100 points each)
Final Exam (semi-cumulative)
Recitation (homework/participation)
Mastering Biology
The grading scale is as follows:
A
93-100%
A90-92.9
B+
87-89.9
B
83-86.9
B80-82.9
C+
C
CD+
D
77-79.9
73-76.9
70-72.9
67-69.9
63-66.9
Percent of grade
40 %
40 %
10 %
10 %
DF
60-62.9
<60
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UNC defines their grades as follows:
“A - Mastery of course content at the highest level of attainment that can reasonably be
expected of students at a given stage of development. The A grade states clearly that the
student has shown such outstanding promise in the aspect of the discipline under study that
he/she may be strongly encouraged to continue.
B - Strong performance demonstrating a high level of attainment for a student at a given stage
of development. The B grade states that the student has shown solid promise in the aspect of
the discipline under study.
C - A totally acceptable performance demonstrating an adequate level of attainment for a
student at a given stage of development. The C grade states that, while not yet showing any
unusual promise, the student may continue to study in the discipline with reasonable hope of
intellectual development.
D - A marginal performance in the required exercises demonstrating a minimal passing level
of attainment for a student at a given stage of development. The D grade states that the student
has given no evidence of prospective growth in the discipline; an accumulation of D grades
should be taken to mean that the student would be well advised not to continue in the
academic field.
F - For whatever reasons, an unacceptable performance. The F grade indicates that the
student's performance in the required exercises has revealed almost no understanding of the
course content. A grade of F should warrant an adviser's questioning whether the student may
suitably register for further study in the discipline before remedial work is undertaken.”
Exams: Exams will be worth 100 pts each and utilize a variety of question formats. There will
be true/false, multiple choice, fill-ins, problems and short answer questions.
Final Exam: The final exam will be semi-cumulative and will consist of true/false, multiple
choice, short answer and problems. Format of Final Exam: 100 pts based on material not
previous tested and 100 pts cumulative.
Recitation: The grade for the recitation portion of this course will be comprised of attendance,
graded assigned problems and in-class group work.
MasteringGenetics™: MasteringGenetics™ is a web-based homework site (and also has
additional learning resources). You will regularly have homework assignments due. The due date
and time will be indicated for each assignment. While the length of time for completion will vary
with the assignment and with the student, you should allow up to 3 hrs for each assignment. If
you have internet issues, then it is YOUR responsibility to get to another computer/internet
source. The videos and animations have all been tested so if you are having problems, you
should try another computer. Do NOT email Dr. Train and ask to change the due date due to
problems with the videos or the website or for any other reason. If you have video problems,
you should go to the library and use a different computer. The due date will only be changed if
there is a modification to the course schedule or if 100% of the class has a problem.
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Lecture Outline
Dr. Train reserves the right to make modifications as necessary
Date
Topic
Reading
Mon 06/22
Syllabus;
Ch 1 pp. 1-16
Ch. 2: 2.1-2.4
Fri 06/26
Course Introduction and What are Genes,
Genetics and Traits?
Transmission Genetics: Mono and dihybrid
crosses; probabilities
Transmission Genetics: Chi square analysis,
autosomal inheritance and molecular basis
Chromosomal Transmission: Mitosis,
Meiosis, Sex-determination and Sex-linked
traits
Gene Interaction
Mon 06/29
Tues 06/30
Wed 07/01
Thurs 07/02
Genetic Linkage and Mapping
Catch up and review
Exam 1
Chromosomal Abnormalities
Fri 07/03
Mon 07/06
Tues 07/07
Wed 07/08
NO CLASS – Independence Day
Chromosomal Abnormalities, continued; TBA
DNA structure and replication
Transcription and RNA processing
Thurs 07/09
Fri 07/10
Mon 07/13
Tues 07/14
Wed 07/15
Thurs 07/16
Fri 07/17
Mon 07/20
Tues 07/21
Transcription and RNA processing, continued
Translation
Catch up and review
Exam 2
Prokaryotic regulation of gene expression
Eukaryotic regulation of gene expression
Gene expression, continued
Mutations and repair
DNA technology
Wed 07/22
Thurs 07/23
Fri 07/24
Mon 07/27
Stem cells and cloning
TBA
Reading Day – NO CLASS
8-11 a.m. Final Exam
Tues 06/23
Wed 06/24
Thurs 06/25
Ch. 2: 2.5, 2.6
Ch. 3: 3.1 (pp. 64-70), 3.2 (pp. 7380), 3.3 (pp. 81, 84-85), 3.4, 3.5
Ch 4: 4.1 (106-110; 112-113; 114116), 4.2 (119-120, 121 Pleiotropic
genes), 4.3 (127-133), 4.4
Ch. : 5.1, 5.2, 5.3, 5.4 (163-164)
Ch 11: 11.1, 11.2 (362-365), 11.3
(369-371), Ch 13: 13.1-13.4
Ch 13: 13.1-13.4
Ch 7: 7.1-7.4
Ch 8: 8.1-8.3 (260-274), 8.4 (278282)
Ch 9: 9.1-9.4, 9.6
Ch 14: 14.1-14.3
Ch 15
Ch 12: 12.1-12. 5
Restriction enzymes: 16.2 pgs 531535; Gel Electrophoresis: 10.2 pgs.
335-337; Southern Blot pgs 341, 344345; PCR 7.5 pgs. 248-250; RFLP pgs
338-341; Sequencing: 7.5 pgs. 250255
TBA
TBA
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