Figure S2
Sf101 phage
Rhizobium sp. CF080
Thiothrix nivea
Cupriavidus metallidurans CH34
Burkholderia sp. CCGE1003
Azospirillum sp. B510
Pseudomonas aeruginosa
Nitrospira defluvii
Competibacter phosphatis
Dechloromonas aromatic RCB
Pseudomonas sp. GM55
Pseudomonas fluorescens F113
Rhodobacter capsulatus
Pseudomonas sp. S9
Flavobacterium columnareATCC49512
Klebsiella pneumonia MGH78578
Serratia fonticola
Acinetobacter pittii
Enhydrobacter aerosaccus
Burkholderia ambifaria
14
24
22
15
14
14
11
51
11
11
11
11
11
8
11
4
14
18
14
28
Sf101 phage
Rhizobium sp. CF080
Thiothrix nivea
Cupriavidus metallidurans CH34
Burkholderia sp. CCGE1003
Azospirillum sp. B510
Pseudomonas aeruginosa
Nitrospira defluvii
Competibacter phosphatis
Dechloromonas aromatic RCB
Pseudomonas sp. GM55
Pseudomonas fluorescens F113
Rhodobacter capsulatus
Pseudomonas sp. S9
Flavobacterium columnare ATCC49512
Klebsiella pneumoniae MGH78578
Serratia fonticola
Acinetobacter pittii
Enhydrobacter aerosaccus
Burkholderia ambifaria
SVILMSLLAVGLFDKISPINLVEHGRNNQIDGMRGFLAIFVLIHHAAIWNGYLSSGVWEAPSSNLLANLGQVGVSFFFMITGYLFFSKIISGDQ-----D
ACMMFASGLAVKSALISPVVTASSNRYGALDGLRGLLAYGVMFHHSMAAYSYFSSGVWYGLDNAVVFQLGKTTVALFFMITGFLFTEKCITGKVN----VFMFIVASYFIRQDTFAKSLTVPSGRYGSLDGLRGVLATGVFIHHAFAMYVYFSGGEWQWSTSPVFNQLGQTTVSLFFMITGFLFTLKALAPTID----LCLALVWPKR-LWRFLDDPPSGQGQRYVTVDGLRGFLALAVVLHHCVISYGFHQTGEWKLPPSSFYSIIGQVGVSIFFMITAFLFWGRLLDQGKR---LD
AILCCLFALP-IFAFVDD-AAGVKERMQTIDGLRGFLAASVMVYHGLINYNYVTVGKWMAADALFYRPLGGVAVMFFFMITAFLFWTRLLRRDGR---PD
VAVCVSWAILRLIAPRLRPQPGSDARYAGIDGLRGLLAFAVFIHHGVITWQYLHTGVWALPPSRLHTHLGQSGVALFFMVTAFLFWDKLLKAGPG---MD
VCVALALLTCGIIRYLKP-IPLPLSRFSTIDGLRGYLAFFVFLHHAAIWYYFLRSGAWQVPPSNLYTHFGQTSVSLFFMITGFLFTHKLLQSKNR--PID
AALLLALGTATLLPEITPRQATSPVRYTSLDGLRGYLAFAVFLSHSSIWYFYLRSGTWDVPPSNFYAHLGQSSVILFFMITAFLFWSKLLDGRVQ--PVD
LILYVAVVVAYLMSRYSE-IPPDQGRFVALDGLRGYLALFVFLYHSALWYFYLRTGQWEVPPSNLYTHFGQSSVLLFFMITGFLFFSKLLDGRTR--GID
FAILMALFSCFVLIRKFG-PPEEQGRYLAIDGLRGYLAFCVFLHHSIIWFFYLKTNQWAVPPSNLYTHFGQTGVAFFFMITGFLFFSKILEGRGK--EID
VAVAFALLSTLAISSQLP-PPSSHGRFLTIDGLRGYLAFFVFLHHSCIWYYYLQTGAWVAPPLRLFVHFGQVGVSLFFMITGFLFFSKIMDDRGR--GVD
IAILVALLSTNLFLGKLV-VPSSHGRFVTLDGLRGYLAFFVFLHHSYIWYYYIHSDVWVLPSSRLFVHFGQVGVALFFMITGFLFFNKLLEGRAR--GID
IVFSIALITVFLLAGLLR-IVPQDDRVSTIDGLRGYLACGVFLHHSAIWYYYLHTGKWVAPPSHLYAHLGQTSVALFFMITGFLFYSKILSSR----PLD
IATGIALTAALCVQKIVP-VHDSSHRHTAIDGMRGYLAFFVFLHHSSIWYFYLHEGRWALPPSNLFSHLGQSSVALFFMITGFLFYSKILSSRDK--KIS
IIFFIAFTTAYIINLKFK-IINNNTRYETIDGIRGFLAIGVFIHHASIWFQYLQIKSWVAPKSNLYNQLGQTSVSLFFMITSFLFITKLLNSENQ--KIN
KYISNKLGIELINS----------GRFTAIDGLRAYLSLFVFFHHFFIFYKWKESGKWEKPEILFIDDLGQVSVAIFFIITGFLFIGKITSGR----HFD
AMIFCVLFMKIINSRLIKIELPIGNRAGCIDGARGYLALMVAVHHYYIFYFWIKTGKWLPPEVQYINSLGKVAVSAFFIITGYLFLGKILRDNRLHIKTQ
SVTIFSLIFTKIN----ILPETNSGRTSTIDGLRGILALSVMTHHFYITYIWKTVGEWKKPENILIDNFGGVAVSLFFLITGYLFISKIRKDE-----VS
SLTLVTWLLNQLPQRM-IVGFDASHRHSPLDGIRGILALSVFTHHFFKNYFFQTTGRWQSPNIDFFTNLGSVPVSLFFLITGYLFFGKLKQPW-----MD
VAIIAWLVARHVPFYRSAVDKSLSMRHPNLDGFRGILATSVVFHHFACNQGLLSTGVWGAP-SDFLRNLGTIPVALFFMVTGFLFWERACRGT-----LD
WTRLYVSRLLRLTPMFIVSLCLIFIIVGFKSGWRMQVSTEELFVSIMKWLPFTAL-GMPNINDVKDSFTINAAVTWTLVYEWFFYFS-LPVISALIKRKV
WRSLYISRLFRLAPLYILVMLVMFTVIFALSGFQVLVPISKLGSQLGKWLLFGAV-GRPNINGFEKSWTLIAGVNWSLRFEWQFYLFGLPVLFLMSRFMN
WKRLYASRVLRLVPLYALIVSSIFGLVFYLSNWALNEPVWEIIKEYWVWMTFVCF-GRPDINAYPMSWTLIANVNWSLKYEIMFYLFAVPAIHVFSRFVQ
WFALYVNRFLRIAPLYWVVVALMLLVVAIKTGFTLAVPPSELVKQVFQWALPAIVRGMPPVNGYQQTSTITAGVTWTLYYEWMFYFS-LPFLAIAAIKRS
WAALYIGRFFRIAPLYIFAVLAMTFIVFWRSGFELREQLGIFLPNMGRWLAFGLNDDMQPINAFPWTIFILMGVTWSIKYEWWFYFS-LVVSAVFVRTGM
WTGFLSSRFHRLYPVYAVAVLLTMILALAATGFEFRTGPLDLLRRLIGWATFKAP----PINGLENAGQIVAYATWSLPYELLFYAA-LPALALLVSPVR
WLQLYISRFMRIYPAYIFAIAIMFTIAFFMTGYTLHESVLSLLKKTIQWGAFRTP----DINGLVETRRIMAGVTWTLPYEWLFYLC-LPALSLLIGRRA
WSRLYLARVFRLVPLYLLVVIGVVSIALYRAGFRLQESMTSFALHLASWLTFTIP-GIAPVNGFAET-IPLAGAVWSLPYEWLFYAC-LPIGSWCIRAAT
WLKLFIGRLLRLVPLYLFMIVSLCIIVMVVSGWVLHEPLLKIAEHLVCWLGFTIL-GAPDLNGVKDTLLIVSGVIWTLPYEWFFYLI-LPVLAMTVRVVP
WLRLYVSRFLRLMPLYAVAMGALFLIVFSLSGATLHEPISVLASEVLRWMAFTVR-GNPDINGIERTSLIMAGVTWSLPYEWCFYML-LPVFALVNRVRV
WLRLYVSRFLRLTPLYFFSMILLFSIVGWVTKENQTDSFSELIGACLKWLGFTIYFGVPDINGFPGTYVVNAGVTWTLPYEWTFYMA-LPLIALAIGVWP
WFRLYVSRFLRLTPLYLFSMVLLFLIVWVLTKNEPAQPTGKLIVDGLKWIGFRVS-GAPDLNGLLGTRYIHAGVTWTLPYEWFFYLF-LPFVALAIGSRP
WTRIFVSRLLRLTPLYLVVISLMLIVVGVQTQWELREPLYNLINNIIRWFLFLQA----NVNQMEETRTITAGVTWTLPYEWSFYFL-LPALALFTGR-WTYIYTSRFMRLVPLYLLAISILLLFVFIKTNWKIETGLSSILIDATKWVLFTIP-GAPDINNVKHTSLIMAGVTWSLPYEWLFYFS-LPLIALTTGLSR
WPIIFISRFFRLVPMYLVSIFLLISIVFIISDWQLNVTPFKLLKEVLQWGTFTIL-SSPTINDLSFTHIINAGVVWSLPYEWLFYFS-LPIISILIFKKK
FFSVYISRFFRIMPLYLLVVMITLFYSFLLTGLSIQIPHSELLKDIVRWLLFVGD----SVNGYTDAKRITAGVTWTLKYEWLFYFS-LPLLFLILKNKV
WSPLYLSRFLRITPLYLLSVLVTIILTFVLSEGVLYVSFFELFKEVSRWLLYVGY----SINGDADARRITAGVTWTLKYEWVFYLT-LPILAILLKERT
WKQIYISRIKRIIPLYLFVFLFILAITLLN-VQITASNYIEFLKWVSDWILFKGG----SFQ-NFESGLVIAGVHWTLIYEWKFYFA-LPLIFVIWQ-QK
WQYLYRSRLQRIVPLYLFLGICIVAIYFT--QQHPPLPLSEWQQWTLRWLSFNNQ----SLK-DFYAWPLVAGAAWTLLYEWGFYFS-LPLLFVLVHPKQ
VRSFFVGRVRRVAPLYLFYATVIVACTLYWFPRNVVDAPIRLLADLLKAVSLGWF-GAFPVNGAEHTGYLSG-VWWTLAYEWRFYVA-IPFLAWFVATRA
108
118
116
110
108
110
107
148
107
107
107
107
105
104
107
89
113
108
107
121
206
217
215
209
207
205
202
245
205
205
206
205
198
202
205
184
208
200
199
218
Sf101 phage
Rhizobium sp. CF080
Thiothrix nivea
Cupriavidus metallidurans CH34
Burkholderia sp. CCGE1003
Azospirillum sp. B510
Pseudomonas aeruginosa
Nitrospira defluvii
Competibacter phosphatis
Dechloromonas aromatic RCB
Pseudomonas sp. GM55
Pseudomonas fluorescens F113
Rhodobacter capsulatus
Pseudomonas sp. S9
Flavobacterium columnare ATCC49512
Klebsiella pneumonia MGH78578
Serratia fonticola
Acinetobacter pittii
Enhydrobacter aerosaccus
Burkholderia ambifaria
SIYMVMISAISLFVFILFFS--------KIHIVSFLFGLLAFLLNKSKIVNGIAKAKVTPIIITAIMIFEMTYFKTTYA-PLPLILCGITFIIIASGCDL
RKALLTGVLTGLGTLALYGWIRGDLGLELLCTAHFLCGIAASLIYNNSVGKRLITSRAFHAAALFCLPVLATSPQGTVV--PDLLATFAIFLSVLGGGSL
LRAALVLCAAMLGAILLFRWQRGGEGGISLYTAQFLGGVMVAYAFKIDRLKAVIEGNIIRWLAAGALVSLFFMQYAYSA--VAVIGNIILFAAVVGGASL
PLAFVPACIWIVFVMPETLSS----AFARNLVAMFVMGMVAASLVRRSPGFRGD-SVLKSAIAVALLAFPLLTRSTAYE-SVSILSLGAFFILVSSGASL
HMVFALVGLAASFAIILTTQS----DLWC-LPAAFFCGMVTASLLHENVRPRML-ENTMSLIALAALALLFSFAKTHAG-VVQIALTGIAFYMMACGADL
RLRPALVSLVLTLALLLYFR-----NFSLNVLQCFLGGIAAAYAIRQPRFVRFARSDRGLVLALAALLATVAGFPGAYA-PGPVLGLGLFFAIVAAGQDF
PMT-ALATTIIIASLILSFW-----RPSPILLCMFLAGGIAALTARSEWLQSLSNGRLGSLLCVCLIGSAVIIFPTAYT-LGPAILLSLAFILITAGCSI
PTSWLLFSAAAVVTLTTVMP-----DVRSPVLYAFGGGIAAASLARVDAIRTRLTHRVRGLVVVACLGITMWLFETAYT-VPALLLLTGAFTIIACGNSI
PPLYIVLSVGSIVTFIIYNPQTHPVHPQLHPLFSFFGGIAASLLVRSDSFRWFCRKDYCSFLVIGLIIAVVVLFQTAYA-IMPLIFISLIFSLIAGGNSL
GRVYIIFSV-LVLIFIFKN------HTYMYHWLSFVGGIAAAYLVRIDYLRYLLRKKVFSMAAILLISATVAFFPSTYD-WAPIAMLSAVFVMIAAGNGV
PVKYLLLSVLSMYAFGYLY------LAGSFYWL-FLGGMVAAILVRFESFRAVAVSRWATLIVLVLAVYVVTMYPSVYDYVQAKFLLVIVFCFIAGGNSI
PVKYLCLAAIALYVFDVYG------YSWSFGWL-FLGGMVAAVLVRYDRFTIFSVSKWATCLIVGSLAWSVTYYPTIYESSVPRLLLIAVFCLISGGNTL
PVPVIILPIVALSAFYMYFAG-----LRPSRFVFFLGGIGAAFLARRSWFCQLAAHKASSLVILASMTCLITLFPSAYG-KIQLVLIFIAFSLVAAGNSL
N-LTAAAVSLAVVLLIYTVFD-----PATIHIKTFIDGMLCAALHHMKIMTGLSSSRLYSAFIIILLYVLVTTYQSSHG-NIQILILSLVFFGISGGNNL
TSFFYTVISLFFILCFFKIYG-----SSIPHLLSFLGGIIPPFIIKYNTKKINFNSNFYS-IIILLCLGLILLFHTSDN-YICKLLIIIVFNLIALGNEM
ATTLIIIVCMLLLINNFKFHSI-IDSRYFIFFMIGGISNYICKLLENNIKLIEILRNRLISIILMVLLIYVFFSGVGIFNIFSIISLLLFFIAIVCGNNL
LAIISLIVGVG--ISYFNINGFGFESHYLIYFIFGGGIAFVQSL--NNKKLSGMMSTSIWSVISILSLVFVIFITPHYSVFLSDILILFFLMPIIFGNSL
IPKWIS-SILVIAF--MVYIFKHKSHHLYALFFL----AIPAVLYKDRFKQFMQTKPAITHIVLGILSIIVLFFTEAYS-WFQMLSLAVIFSFIVSGYSVCQWQNIAMLMISLPVLYYVFTHTIIKLYWLFLL----AFFAVWLEDFFKNLLAKFPVVFAIALCLLTLFILFETSAYS-YWQMLLCGLLFCFIANGFTY
WRKLLALAIVTFCAALFGPPG--------GMALLFAFGALAFEASRHRAIRSLLGTKSAATVALLILAVAPYP-AERYS-IEGALPLLPVFLCVACGNTF
297
315
313
303
300
299
295
339
304
297
299
298
292
295
298
283
304
291
294
308
Sf101 phage
Rhizobium sp. CF080
Thiothrix nivea
Cupriavidus metallidurans CH34
Burkholderia sp. CCGE1003
Azospirillum sp. B510
Pseudomonas aeruginosa
Nitrospira defluvii
Competibacter phosphatis
Dechloromonas aromatic RCB
Pseudomonas sp. GM55
Pseudomonas fluorescens F113
Rhodobacter capsulatus
Pseudomonas sp. S9
Flavobacterium columnare ATCC49512
Klebsiella pneumoniae MGH78578
Serrati afonticola
Acinetobacter pittii
Enhydrobacter aerosaccus
Burkholderia ambifaria
YGILRLNITRKLGETTYSVYLLHGIFLYCLMTWIIPNNYTENTF-----IILVSTTAFLITFTSCLTFKLIETPFIKLTKQTTTLVKELIPTLTNNNQ-WGLLKTRAAIWLGDISYGVYLIHGLALWLSYYNLSRAGLLDAID-GPIFLLLLPAIGLVVLAISSVSYIRVELPMIKLG--RKLGSPKTSSRVELA---FGLLKHKSAVWLGDISYGIYLMHGLVLWLVLNMLAKAGILSQLG-LVGYWLVTFATAASIVLLASCSYALLEKPVMGLLPARKQDRVRGYKQPGLRTW-FGLLASRSAVRLGSVSYGIYLLQGIVITVLHSP-RVLGAFACKG-PEQFWLTTIAVGLVLVCVAAASYHFVERPCIRLGKKIGKAPESARQTHVEMGDGT
FGLLRLKSAQRLGHVSYGVYLLQGIPITLLFWH-APFRAWAVVS-PMHYWLALLVCAALLCVVAALTFALIERPFIQLGKSIHSPAS-------WLKAGA
RGTLTRQPVLWLGEISYGVYLLHGIVLWTLITANGPLRALIGAD-ESLYLLALTVAGVLVVALASLVHLTVERPAIRFGKRSRDPRQ------------A
FGLLNLSVSRFFGEITYSLYLLHGIVLYVIFEIVLGNQAAKEFD-TRQHWMIIYAATPITVVLSYLSFRYIERPSMSASKGLGARIKS----LLRNTYRP
YGILEWPTSVLLSEMGYSLYLLHSLLLFAVYRLVLG-EWASTLS-ATEHWSVVLALVPILIVLCFATFRLIEQPAMAAVPRCHAWLVA----HLNE--RP
FGILRSSISRVLGELSCSIYLLHGMALFILFKFVVGPNHAQLLS-AQQHWMLVIAISPVILFISYWTFRLIEQPAMRATNTVTVWVSSRLTWRFRTYVVS
FGLLTNAVSRALGELAYSIYLLHGIVLFLLFRYVIGFEKSKLLQ-PIDYWSAIIAVSPILIFISYLSYRKIERPALLSTDGLTSWLRN----KINSYSEA
FGVLNSKVSRVMGEMAYSIYLLHGLVLFVAFRLVIGASLGKALS-PSQYWGVIVTLTPVLILICGLTFRFIERPAMKMTGPLTDWIRA----KKTNVIAG
FGLLKLKVSLVMGEMAYSMYLLHGVLLFVIFRFIFGGARASELT-PLQYWGVIVLATPILMMICGLTFRFVERPAMRSVDTLTHWIRA----KKKGRFER
FGALTNRVSRALGEITYSIYLLHGLILYSLMKLVLFPDTNAALPSPFAFWCIVLCVTPVLITMSMLTFKFIEQPAMQHADTLATRLKASWTAFRSRDARA
FGVLSWKTSRVLGEMAYSIYLLHGLILFTTFNFIINSETSIELT-PYQYWILIFAIAPAVVIISAITFVMIEKPSMDKTQKIANQICN---LSSKK---FGVLKNTTLKFLGEISYSTYLIHGIIIFITLYFGFSLEVVEKMS-PSTFCSIIFLITPIIILTSFLSYRNIEKPFMDYSKKINYDKIN---YSITEFYKR
FGALTLKGARLLGEISYSIYLIHGCVIFSIF-ILMNKFSGLS-LSEYLILMPFVTIA--VVFISSLTYRFIEAPCINIGKKIQNIYRFNGKKAL-----FGLLKLKSSIRLGEISYSIYLMHGIVFFVIF-IFLFDVNKMNGWVEFFIYMPFSLML--VVFFSVYTYQYIEKPFVDLSHIIR-KKRINTNEII-----FGILNHKGLKVLGEISYSIYLIHGLVLYTIFTVINIVDLKTISLEKYYSFFLPTALL--VTIVSLFTYKFIECPFLRRPLKKL----------------FGVLYQQGLKVLGELSYSLYLTHGLVMYIWFNLLHLHDFS-QSMTAYVWTYPLVLVF--VVMFAVIGYNYIEKPLMHRPNSRVLSP-------------YGVLQTRPLALLGTASFSIYMLHMAIVYALVRAFNKFVFPINSVDDSGIWALSFACALVAVFCALLTYRYIEHPFIAKRNDARPARRTIEPAREQSTAAL
390
408
410
401
391
386
390
431
403
392
394
393
392
387
394
373
394
372
377
408