XIX-QIP IN DIPSAR, DELHI
RECENT DEVELOPMENT IN PHARMACEUTICAL CHEMISTRY
A quality improvement program on topic Recent Development in Pharmaceutical Chemistry was
organized on 9th March 2015 to 20th March 2015 by DIPSAR Delhi. Days aimed to provide an insight to
the fellow pharmacy teachers working across the country about the recent development in various facts
of health-care profession .Also to provide the information regarding drug designing and synthesis by
applying newer techniques.
The two week QIP was co -ordinate by Dr. Sharad Wokade , with the help of Mrs. Amrita Parle &
Dr.R.b.Bodla.
First day
(1) Inaugural session –
The inauguration ceremony was done by Dr.P.D.Sethi -Chairman, Ayurvedic Pharmacopeia of India,
shared few upcoming activities in analytical techniques for analysis of multi component drug
formulation.
Dr.D.P.Pathak in his welcome speech highlighted the importance and objective of organizing Faculty
Development Program.
(2) Lecture by – Dr Ramesh Bodla (Assistant Professor,DIPSAR)
Topic-Protocol for Drug Discovery
A road map to drug discovery and development.
(3) Lecture by-Dr. Rajni Mathur (Assistant Professor,DIPSAR)
Topic-Aqueous extract of leaves Psidium Guajava for inhibit hepatic GLUT-2.
Explain about the most common cause of childhood overweight and obesity and prevention. The high
fructose intake raise the circulating level of insulin and leptin and hepatic GLUT-2 expression to
promote insulin resistance, dyslipidemia and hypertension that favorably reset with PG.
Second day
(1) Lecture by- Professor (Dr.) D. P. Pathak (Director DIPSAR)
Topic-Nitric oxide: Biological Significance and Detection.
Provided the information about the role of NO in Nervous system, circulatory system, muscular system,
immune system and digestive system in human body.
(2) Lecture by- Dr. Devendra Pathak(Director Rajiv Academy for Pharmacy- Mathura)
Topic –Rational use of steroid drugs
Awareness to steroids use and misuse.
(3) Lecture by-Dr.Manish S.Lavhale( Pharmazz India Pvt. Limited , Greater Noida )
Topic- Discovery and Development of Centhaquin.
As a resuscitative agent in hypovolemic shock.
Third day
(1) Lecture by Dr. Jainendra Jain (Director ,Ram-Eesh Institute of Vocational and Technical
Education,3, Knowledge Park I, Greater Noida.)
Topic-Molecular docking interactions in Computer Aided Drug Design.(protein ligands
docking)
He discuss about the Introduction to protein-ligands docking, Practical aspects, searching for pose,
Scoring functions , Assessing performance and the various new software’s use in drug discovery .
(2) Visit to- Animal House in DIPSAR
(3) Demo - Zeta Potential Analyzer(Dispersion Tech-Version5.10)
Is the powerful tool in understanding the stability of a particular suspension .It is used for the
Measurement of Molecular size, Particle size, Molecular weight, Zeta potential, Protein mobility,
Microrheology. The Particle size range from 0.3nm to 10µm.
(4) Demo –Homogenizer (GEA Niro Soavi Technical Datasheet Laboratory Homogenizer)
This equipment used for the homogenization of various types of material, such as tissue, plant food, soil,
and many others.
Fourth day
(1) Lecture by-Dr.Vijay Bhalla (Director-Lloyd School of Pharmacy,Treasurer-IPGA)
Topic- Microbial Resistance to Antibiotics, Role of Community Pharmacists
Give the tip to avoid the resistance to antibiotics .Avoid misuse of antibiotic, Avoid self
prescription, Do not use antibiotics in viral or other infections ,Take antibiotics in doctors
supervision ,Complete the course of antibiotics even if you feel better, Do not miss any dose, Do not
save any drug for your next time treatment, Do not demand antibiotics from medical stores directly,
Do not take antibiotics which are prescribed for your relatives
(2) Lecture by-Dr. Sayeed Ahmad (Associate Professor; Bioactive Natural Product Laboratory
Department of Pharmacognosy & Phytochemistry ,Jamia Hamdard ,New Delhi )
Topic- HPTLC- Planar Chromatography in Drug discovery
(3) Demo-HPLC
(4) Demo –CHNSO Analyzer.
Fifth day
(1) Lecture by-Dr. Deepti Jain (Associate Professor, School of Pharmaceutical Sciences, RGPV
Bhopal )
Topic-FTNIR: A Versatile Tool for Pharmaceutical Analysis.
A New spectroscopy technique for determination of impurities, it can apply directly to incoming raw
material at loaded dock. Can be use to determine the moisture content, content uniformity, tablet API
etc.
(2) Lecture by-Dr.S.K.Jain (Professor and Director ,Sagar Institute of Research & Technology –
Pharmacy Bhopal)
Topic-Role of Bioinformatics in Identifying New Molecule Targets for Drug Discovery.
Bioinformatics deals with the exponential growth in biological data has led to the development of
primary and secondary databases of nucleic acid sequences, protein sequences and structures. Some of
the databases include GenBank, SWISS-PROT, PDB, PIR, SCOP, CATH, etc. These databases are
available as public domain information and hosted on various Internet servers across the world. Basic
research and modeling is done using these databases with the help sequence analysis tools like BLAST,
FASTA, CLUSTALW, etc., and the modelled structures are visualized using visualization tools such as
WebLab, MOLMOL, Rasmol, etc.
(3) Lecture by-Dr. Amit Bhargava (Oncologist-Batra Hospital and Medical Research Centre
New Delhi )
Topic- Hematopoietic Stem Cell Transplantation.
Provided the information for Hematopoietic stem cell transplantation. (HSCT) is the transplantation
of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or
umbilical cord blood. It may be autologous (the patient's own stem cells are used) orallogeneic (the stem
cells come from a donor). It is a medical procedure in the field of hematology, most often performed for
patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia.
(4) Lecture by- Dr. Anil Thakwani (Senior Consultant,Department of Radiation oncology,Batra
Hospital and Medical Research Centre, New Delhi )
Topic -Recent advances in radiotherapy and radio surgery
Sixth day
(1) Lecture by- Dr Y. Kumar (Guest Lecturer in DIPSAR)
Topic- Calculation of λmax and use of shift reagents in UV-Visible Spectrophotometry.
(2) Visit – INMASS-DRDO, Delhi (Guided by Dr. Aseem Bhatnagar)
Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi under the aegis of Defence
Research and Development Organization (DRDO), is engaged in research and developmental work
in radiation sciences, Neuro-Computing and Medical Image Processing.
Seventh day
(1) Visit- Jamia Hamdard ,New Delhi
Here Dr. Sayeed Ahmad given the demonstration of HPTLC and other instruments.
(2) Visit - Jubilant Chemsys Limited ( B Block, Sector 58, Noida)
The company is a part of Jubilant Drug Discovery and Development Services, under the flagship of
Jubilant Life Science Limited, offers services in synthetic, organic and medicinal chemistry areas to
various pharmaceutical and biotechnology.
Eighth day
(1) Lecture by-Nitin K. Jain(Scientist –E, Department of Biotechnology ,Ministry Of Science &
Technology)
Topic- Protecting Pharmaceutical/Biotechnology Inventions
(2) Lecture by- Prof. B.Narasimhan (Head & Dean ,Faculty of Pharmaceutical Science
NDV,Rohtak)
Topic-QSAR by Hansch Analysis.
(3) Lecture by-Dr. Sharad Wokade (Assistant Professor, DIPSAR)
Topic- Drug Discovery & Animal House Management
(5) Lecture by-Dr.Mohammad Shaquiquzzman(Associate Professor, Jamia Hamdard ,New Delhi )
Topic-Handling of NMR in Pharmacy
Ninth day
(1) Lecture by-Mr. Abhishekh Jain (CEO,Grace Wellness)
Topic-Stress Management
(2) Lecture by-Dr. Milind Parle(Dean, Faculty of Medical Science,HISAR, Haryana)
Topic- Fundamental Elements of Research.
(3) Lecture by-Dr. Poonam Pipalini (Professor-Panjab University ,Chandigarh)
Topic-Alzheimer’s disease ,The Mystery Unfold……………..
(4) Lecture by –Dr.Thirmurthy Velpandian (Department of Ocular Pharmacology and
Pharmcy,AIIMS,Delhi)
Topic-pK of Antimicrobial Agent Altering PD: Relevance of MIC.
(5) Lecture by –Dr. Hina Gokhale (Director,HR,DRDO,New Delhi)
Topic- Research /Innovation and Human Capital Management.
Tenth day
(1) Lecture by-Dr.P.L.Sahu (Principal Scientific Officer,IPC,Ghazibad)
Topic- Impurity Profiling and Genotoxicity.
(2) Lecture by-Shashank K. Singh (Senior Scientist,CSIR)
Topic-Cancer Drug Discovery from Natural Pdt.
(3) Valedictory Session by -T.R.Bhardwaj (Baddi University), Professor (Dr.) D. P. Pathak (Director
DIPSAR)