Cardiology Rotation Goal To integrate basic pharmacy-related concepts and cardiology patient care through patient care activities, discussions, and selected exercises. Objectives At the completion of this rotation, the student should be able to: 1. Demonstrate a comprehensive understanding about the clinical use, pharmacokinetics, route of administration, adverse effects, and drug interactions of the following: • Antidysrhythmic drugs: quinidine, procainamide, disopyramide, lidocaine, tocainide, mexiletine, flecainide, bretylium, amiodarone, beta blockers, verapamil, diltiazem, ethmozine, propafenone, and digoxin • Inotropic agents: digoxin, amrinone, and milrinone • Antihypertensives: diuretics, beta blockers, prazosin, methyldopa, guanadrel, hydralazine, clonidine, guanabenz, captopril, minoxidil, guanethidine, sodium nitroprusside, diazoxide, and calcium channel antagonists • Antianginal agents: nitrates, beta blockers, and calcium channel antagonists • Anticoagulants and antiplatelet drugs: heparin, warfarin, aspirin, dipyridamole, sulfinpyrazone, and thrombolytic agents • Sympathomimetics: epinephrine, norepinephrine, isoproterenol, dopamine, dobutamine, and phenylephrine • Parasympatholytics: atropine • Vasodilating agents: nitrates, hydralazine, prazosin, captopril, minoxidil, nifedipine, sodium nitroprusside, nitrates, enalapril 2. Discuss the pathophysiology, associated laboratory and physical findings, and recommend the therapeutic maneuvers for the following disease entities: • Acute myocardial infarction • Angina pectoris including effort angina, Prinzmetal's angina, and unstable angina • Supraventricular dysrhythmias: atrial fibrillation, atrial flutter, multifocal atrial tachycardia, PSVT • Ventricular dysrhythmias: ventricular tachycardia, ventricular fibrillation, Torsades de Pointes • Pre-excitation syndromes: Wolf-Parkinson-White • Atrioventricular blocks • Heart failure • Hypertension