Brian D. ATHEY, PhD
Michael A. Savageau Collegiate Professor
and Chair Department of Computational
Medicine and Bioinformatics
Professor, Department of Psychiatry
Co-Founder and Chief Science Officer,
tranSMART Foundation
University of Michigan Medical School
bleu@umich.edu
O: 734.615.5774
C: 734.972.3624
Brian is the Michael A. Savageau Collegiate Professor and Chair,
Department of Computational Medicine & Bioinformatics, Professor
of Psychiatry and Internal Medicine at the University of Michigan
Medical School. He also serves as a co-director of the University of
Michigan Data Science initiative. A national leader in translational
biomedical informatics, Dr. Athey is the founding Principal
Investigator of the NIH Roadmap National Center for Integrative
Biomedical Informatics (NCIBI), one of eight NIH National
Biomedical Computing Centers (2006-2012). Brian currently serves
as co-founder and Chief Scientific Officer of the tranSMART
Foundation, a non-profit company founded to coordinate the
development of the open source tranSMART community and its
code base. The tranSMART platform supports an integrated open
data sharing and analytics platform used world-wide to accelerate
clinical and translational research.
Academically active in the field of psychiatric pharmacogenomics,
Brian is Chair of the Scientific Advisory Board of Assurex Health; he
also serves on the SAB of One Mind for Research. Brian has led
the National Library of Medicine (NLM) Next-Generation Internet
(NGI) Visible Human Project and the DARPA Virtual Soldier Project.
He is a key a national leader in the NIH Clinical and Translational
Scientists (CTSA) Informatics Community. Brian is a highly sought
after national informatics lecturer and advisor, with over 100 papers
and conference proceedings, 170 invited talks, and numerous
advisory boards related to bioinformatics and computational
medicine. Brian has served as a special advisor to the Defense
Sciences Office (DSO), DARPA (1994-1999); and to the NIH Office
of the Director (OD) and to the NIH Chief Information Officer (CIO)
(2007-2010). Brian was awarded a “Peace Fellowship” from the
Federation of American Scientists (FAS) in 2000-2004 for his work
countering Bioterrorism in the 1990s.
Robert Lee Bard is a Research Associate at the University of
Michigan Medical School in the Division of Cardiovascular Medicine.
Mr. Bard has been employed with the University of Michigan since
1996 and conducts research involving the cardiovascular system
and vascular function. Mr. Bard has been actively involved in
numerous studies with Dr. Robert Brook investigating the health
effects of air pollution.
Robert BARD, MS
Clinical Research Coordinator
Division of Cardiovascular Medicine
Internal Medicine
University of Michigan Medical School
bbard@umich.edu
O: 734.998.5627
Benjamin BASSIN, MD
Assistant Professor, Emergency Medicine
Associate Director, Survival Flight
University of Michigan Medical School
bsbassin@umich.edu
O: 734.763.2134
C: 734.358.0883
Dr. Bassin is an Assistant Professor in the Department of
Emergency Medicine. He received a BS in Movement Science and
Physiology from the University of Michigan in 1998 and his Doctor of
Medicine degree from the University of Michigan Medical School in
2005. He completed residency training in Emergency Medicine at
the University of Cincinnati where he served as Chief Resident. Dr.
Bassin returned to the University of Michigan in 2009 as faculty in
the Department of Emergency Medicine. His academic interests
include improving the quality, delivery and standardization of care to
critically ill patients, advanced airway interventions, and the
development of computerized clinical decision support tools.
Additionally, he has a focus on LEAN-based healthcare design and
was an integral component of the planning, design and
implementation team for the largest ED-based ICU in the country,
the U-M Emergency Critical Care Center (EC3) where he currently
serves as the EC3 Director of Clinical Operations. He is also the
Associate Medical Director for Critical Care Transport and the
Associate Service Chief for the Department of Emergency Medicine.
In these roles, he has an established track record of administrative
leadership in process improvement, quality assurance, risk
mitigation, and throughput optimization utilizing lean-based
strategies.
Dr. Bragg-Gresham has spent most of her career as a Biostatistician
focused on improving the outcomes of dialysis patients. After ten
years of working in the field of dialysis research as a Biostatistician,
Dr. Bragg-Gresham returned to school and completed her PhD in
Epidemiology. Her interest has changed to focus primarily on predialysis chronic kidney disease (CKD). Dr. Bragg-Gresham is
currently an investigator on the CDC Chronic Kidney Disease
Surveillance Project, the VA Kidney Registry Project, and the Joint
Institute project assessing the differences in CKD between the US
and China. Her current research focuses on CKD progression,
geographic variation in CKD, and environmental factors (such as air
pollution) and CKD.
Jennifer BRAGG-GRESHAM, PhD
Assistant Research Scientist
Kidney Epidemiology and Cost Center
(KECC)
School of Public Health
University of Michigan
jennb@umich.edu
O: 734.763.1604
C: 734.945.4192
Robert BROOK, MD
Professor of Internal Medicine
Division of Cardiovascular Medicine
University of Michigan Medical School
robdbrok@umich.edu
O: 734.998.5627
C: 734.626.2665
Frank BROSIUS, MD
Professor and Chief of Nephrology
Scholar, A. Alfred Taubman
Medical Research Institute
Director of the George O’Brien Kidney
Center
University of Michigan Medical School
fbrosius@umich.edu
O: 734.936.5645
C: 734.657.8844
Dr. Brook is a professor of medicine in the Division of
Cardiovascular Medicine at the University of Michigan. Dr Brook
joined the University of Michigan faculty as a physician-scientist and
was promoted to Associate Professor in 2008 and full Professor in
2014. He is a Fellow of the Society for Vascular Medicine (FSVM),
the American Society of Hypertension (FASH), and the National
Lipid Association (FNLA). His clinical interests are in resistant and
secondary hypertension, orthostatic hypotension, complex lipid
disorders, and primary cardiovascular disease prevention. He is an
American Society of Hypertension (ASH)-Designated Specialist in
Clinical Hypertension and the director of the ASH Comprehensive
Hypertension Center at the University of Michigan. Dr. Brook has
authored over 150 peer-reviewed publications in the areas of
vascular biology, atherosclerosis, cardiovascular imaging,
hypertension, prevention, and hyperlipidemia.
His main research interest has been the cardiovascular effects of air
pollutants with an emphasis on understanding the biological
mechanisms by which they cause heart diseases, in particular
abnormalities in vascular function, insulin resistance and blood
pressure. His studies have helped to foster the field of
“Environmental Cardiology”. He served as the Chair and lead author
on 2 Scientific Statements by the American Heart Association
regarding the cardiovascular effects of air pollution in 2004 and in
2010.
Frank Brosius, MD is Professor and Chief of Nephrology, Scholar of
the A. Alfred Taubman Medical Research Institute, Director of the
University of Michigan George O’Brien Kidney Center and an active
member of the National Institute of Health’s diabetes and kidney
disease initiatives and sponsored science projects. He is
corresponding PI for 2 multi-PI NIH grants for systems biological
investigation of the basis of diabetic complications and is one of 2
PIs of a recently completed Phase 2 trial of JAK inhibitors in diabetic
kidney disease. He is annually listed in Best Doctors in America,
has served as Chair of the American Heart Association’s Kidney
Council and is Chair of the Research Advocacy Committee for the
American Society of Nephrology. His laboratory has over 25 years
of experience in the study of diabetic kidney disease and he has
published over 100 articles in high quality scientific journals.
His research focuses on:
 Identification of effective treatments and biomarkers for
diabetic complications using systems biology and
translational approaches.
 How glucose uptake promotes specific cellular signaling
responses that lead to disease responses in diabetic kidney
disease and other diabetic complications.
 Testing new concepts of human diabetic kidney disease and
its treatment in robust mouse models that his laboratory has
generated and validated.
Dr. Burmeister has been on the faculty at University of Michigan
since 1991, where in addition to her research she directs the
Bioinformatics graduate program. Her research as a geneticist has
resulted in >150 publications, including in Nature, Science, Nature
Genetics, Neuron, PNAS etc. She reviews for NIH and European
and Asian agencies. She is on the board of directors of the
International Society for Psychiatric Genetics, and in the budding
Chinese Society for Psychiatric Genetics.
Margit BURMEISTER, PhD
Research Professor, Molecular and
Behavioral Neuroscience Institute
Professor of Psychiatry, Human Genetics,
and Computational Medicine &
Bioinformatics
University of Michigan Medical School
margit@umich.edu
O: 734.936.2186
C: 734.239.2026
The Burmeister lab uses an integrative genomic approach to
understand rare genetic neurological diseases and common brain
disorders. She has identified >10 different neurological disease
genes. Current approaches include integration of data from mRNA,
DNA, tissue culture and animal models, and can be expanded to
metabolomics and proteomics, and epigenetics in the JI project with
Professor LI Ming, where we study the effect of pesticides, iron and
lead on DNA. In collaboration with Dr. Srijan Sen, she has started
extension of Dr. Sen’s “internship” project to Chinese medical
interns, starting in 2015.
John M. Carethers, MD is the John G. Searle Professor and Chair of
the Department of Internal Medicine at the University of Michigan
since November 2009. As Chair, he oversees over 750 paid faculty
in their academic, clinical, and teaching roles as it relates to the
overall integration with the health system’s missions of clinical
excellence, education, and discovery. Dr. Carethers is a trained
gastroenterologist and physician-scientist who focuses his research
in the area of hereditary colon cancer genetics.
John Michael CARETHERS, MD
John G. Searle Professor and Chair
Department of Internal Medicine
University of Michigan Medical School
jcarethe@umich.edu
O: 734.615.1717
C: 858.829.7438
Dr. Carethers received his BS degree in Biological Sciences with a
minor in Chemistry from Wayne State University, and his MD with
high distinction from the same institution. Dr. Carethers did his
internship and residency in Internal Medicine at Massachusetts
General Hospital, followed by a fellowship in gastroenterology at the
University of Michigan. He was then recruited to the University of
California San Diego where he grew his laboratory-based research
in the area of DNA mismatch repair and colorectal cancer
pathogenesis, saw medicine and gastroenterology patients, and
served as the main physician for hereditary colon cancer referrals in
Southern California. He was the founding Director of the NIH-funded
UCSD Gastroenterology Center grant, and was the director of the
gastroenterology T32 training grant. Dr. Carethers also has
interests in colorectal cancer disparities as it relates to genetics and
outcomes. He is the former PI of the SDSU/UCSD Cancer Center
Comprehensive Partnership U54 grant, which addresses cancer
disparities. He is a Senior Associate Editor for Gastroenterology,
the highest impact gastroenterology journal. He completed a 2-year
appointment on the National Commission for Digestive Diseases, a
U.S. Congressional Commission after his appointment by Elias
Zerhouni, MD, then Director of the NIH.
Dr. Chen graduated from The Third Military Medical University in
Chongqing, China with a Bachelor’s degree in Medicine. He earned
the MSc degree in Biochemistry from The Academy of Military
Medical Sciences and the Doctor of Philosophy in Molecular
Genetics from the University of Western Ontario. In addition to his
other academic responsibilities, Dr. Chen is Director of the Center
for Advanced Models for Translational Sciences and Therapeutics,
and Vice-Chair for Basic and Translational Research at the
Department of Cardiac Surgery.
Eugene CHEN,
, MD, PhD
Frederick G.L. Huetwell Professor of
Cardiovascular Medicine
Vice-Chair for Basic & Translational
Research, Department of Cardiac Surgery
Director, Center for Advanced Models for
Translational Sciences and Therapeutics
University of Michigan Medical School
echenum@umich.edu
O: 734.647.5742
C: 734.846.9880
The long-term goal of his research program in vascular medicine is
elucidating the molecular basis of obesity/diabetes-induced
cardiovascular diseases (CVD) and stroke, and developing new
drugs/technologies to study and treat diabetes and CVD. Dr. Chen’s
laboratory has made a series of significant contributions to
understanding the role of PPARg activation as a determinant of
vascular cell gene expression and cellular function and has been
among the first to define the role of PPARg activation in the
cardiovascular system. The discovery of the high affinity
physiological PPARg ligands, nitro-fatty acids advances the
understanding of endogenous PPARg modulation and provides
novel therapeutic strategies for treating obesity/diabetes and CVD.
Dr. Chen was the first one to clone the exendin-4 (BYETTA, the drug
name for Exendin-4) gene in 1995.
Marisa Conte is a Research and Data Informationist at the University
of Michigan’s Taubman Health Sciences Library. She partners with
researchers across the translational spectrum to integrate
information resources and services into clinical and basic science
labs and research units, and teaches advanced information
management skills in several postgraduate curricula.
Marisa CONTE, MLIS
Research and Data Informationist
Taubman Health Sciences Library
University of Michigan Medical School
meese@umich.edu
O: 734.615.8889
C: 734.377.7177
Ms. Conte’s areas of expertise include expert literature searching,
data management (with a focus on curation of research data for
preservation and reuse), biomedical informatics, and team science.
She is currently partnering with Dr. Kai Zheng on a supplemental
award from the National Library of Medicine to evaluate and improve
interdisciplinary international collaborations.
Dr. Dong joined the Division of Musculoskeletal Radiology in 2007
after finishing pediatric and musculoskeletal radiology fellowships at
the University of Michigan. Throughout her MRI research, Dr. Dong
continually works toward translating these techniques into clinical
practice. As PI on a Radiology Society of North America Research
Scholar grant, she has been the leader in the proposed clinical
research study of quantitative MRI biomarkers as early predictors of
response to therapy in sarcoma.
Qian DONG, 董倩, MD
Associate Professor of Radiology
University of Michigan
bingch@umich.edu
O: 734.936.4365
C: 734.276.5493
Taking advantage of clinical experience in musculoskeletal MR
imaging and involvement in diffusion MRI research projects, Dr.
Dong’s current research fits logically on the priorities of the division
that provides imaging care for all patients with soft tissue sarcomas
within the institution. It also fits with the department focus on
encouraging quantitative biomarker imaging research and
translational imaging research, both of which are current priority
areas for the NIH.
Ms. Gao received her Master degree of Science in Nursing and two
post master Nurse Practitioner (NP) certificates in Acute Care and
Gerontology from the University of Michigan school of Nursing. She
has been a clinical preceptor for NP graduate students. She is a
committee member of International Council of Nurses.
Li GAO, 高黎, MS, NP
Nurse Practitioner, Adult Medical
Observation Services
Department of Emergency Medicine
University of Michigan Health System
ligao@med.umich.edu
O: 734.615.2765
C: 313.574.8738
Michael E. GEISSER, PhD
Professor of Rehabilitation Psychology and
Neuropsychology
Co-Chair, Medical School Institutional
Review Board
University of Michigan Medical School
Dr. Geisser is a Professor of Rehabilitation Psychology and
Neuropsychology in the Department of Physical Medicine and
Rehabilitation at the University of Michigan. He also serves as CoChair of the Medical School Institutional Review Board (IRBMED).
His primary area of research involves studying the influence of
psychosocial and neural factors on the experience of both acute and
chronic pain. Dr. Geisser has served as a board member of
IRBMED since 2001, and was appointed as Vice-Chair in 2004, and
Co-Chair in 2006. Dr. Geisser also serves as the Co-Director of the
Regulatory Support Unit for the Michigan Institute for Clinical and
Health Research.
mgeisser@umich.edu
O: 734.763.6501
C: 734.730.2114
Joshua GLAZER, MD
Critical Care Fellow
Department of Internal Medicine
Critical Care Medicine
University of Michigan Medical School
glazerj@med.umich.edu
O: 734.763.9077
Dr. Glazer is currently completing a Clinical Fellowship in Critical
Care Medicine. He recently matriculated from the Emergency
Medicine Residency at the University of Michigan Health System
(UMHS) where he also served as Chief Resident. Throughout his
training, Dr. Glazer has been intimately involved in the design and
implementation of the Emergency Critical Care Center (EC3). His
notable contributions thus far include: 1) highly sensitive and specific
automated algorithms which leverage the electronic medical record
(EMR) to identify “index admission diagnoses” pertinent to the EC3
(severe sepsis, hemorrhagic shock, post-cardiac arrest, etc); 2) nowoperational evidence-based EMR order-sets to facilitate
standardized care of critically ill patients; 3) an IRB-approved deidentified registry to enable retrospective interrogation of quality
improvement and patient safety data for research purposes and
publication; 4) hospital impact metrics relevant to implementation of
the EC3; and, 5) a novel EMR-based automated disease severity
scoring system to improve triage and appropriate disposition of
patients within the Emergency Department.
Dr. Gunnerson is an Associate Professor in the Departments of
Emergency Medicine, Anesthesiology, and Internal Medicine. Prior
to his arrival at the University of Michigan in 2013, Dr. Gunnerson
was an Associate Professor in the Departments of Emergency
Medicine and Anesthesiology at Virginia Commonwealth University
Medical Center (VCUMC) in Richmond, VA.
Kyle GUNNERSON, MD
Associate Professor, Emergency Medicine
Director, Emergency Critical Care Center
University of Michigan Medical School
kgunners@med.umich.edu
O: 734.763.2134
C: 804.514.7776
Margaret GYETKO, MD
Senior Associate Dean for Faculty and
Faculty Development
Professor of Medicine
University of Michigan Medical School
mgyetko@umich.edu
O: 734.612.0058
C: 734.660.1634
Dr. Gunnerson’s research interests include a wide range of critical
illness, specifically on early identification and resuscitation of
patients in shock or at risk for developing subsequent organ
dysfunction. Dr. Gunnerson’s research includes several large
collaborative projects funded by both industry and governmental
funding agencies. These have ranged from the discovery and
development of novel biomarkers in critical illness, treatment of
severe sepsis and septic shock and in the development of noninvasive technology used for the identification and treatment of
patients with critical illness and injury.
Since 2007, Margaret R. Gyetko, MD has served as the Senior
Associate Dean for Faculty and Faculty Development in the Medical
School. Dr. Gyetko is the senior advisor to the Dean on faculty
issues, and is responsible for oversight of the appointment,
promotion and tenure processes. Under her leadership, the Medical
School has developed a robust faculty development program
designed to support the acquisition of skills in teaching and research
to further the advancement of faculty careers. Dr. Gyetko received
her medical degree in 1981 from Michigan State University,
completing both her residency (1982-84) and a fellowship in
pulmonary and critical care medicine (1988) at the University of
Michigan. She joined the U-M Medical School faculty in 1988.
Her clinical interests are focused on acute lung injury and
immunologically mediated lung diseases, inflammatory lung
diseases, and the role of lymphocyte populations in acute lung
inflammation. Her research addresses lung inflammation and
immune responses, with emphasis on the role of the pulmonary
microbiome in lung health and disease. Dr. Gyetko’s outstanding
credentials in faculty affairs administration include seven years of
service as the Department of Internal Medicine’s associate chair for
faculty affairs. Her commitment to addressing faculty issues includes
service from 2002-04 as chair of the Medical School’s Task Force to
Evaluate the Instructional Track. At the University level, she was a
member of the Gender in Science and Engineering Committee and
currently serves on the Committee to Consider a More Flexible
Tenure Probationary Period.
Dr. He is a Research Assistant Professor in the UM Kidney
Epidemiology and Cost Center and Department of Biostatistics. He
received his PhD in Biostatistics from the University of Michigan. He
also has training and experience in clinical medicine and
epidemiology. For the past several years, Dr. He has been working
on statistical methods and Quality Measure development for
analyzing large-scale data arising from biomedical studies. His
research interests include survival analysis, high-dimensional data
analysis, statistical genetics and statistical methods for
epidemiology.
Kevin Zhi HE, 何志, PhD
Research Assistant Professor
Biostatistics Department
School of Public Health
University of Michigan
kevinhe@umich.edu
O: 734.764.2279
C: 734.709.6355
James P. HOLLOWAY, PhD, MNE, CAS
Arthur F. Thurnau Professor
Vice Provost
for Global and Engaged Education
University of Michigan
hagar@umich.edu
O: 734.763.0395
C: 734.846.0891
Professor Holloway earned Bachelors and Masters degrees in
Nuclear Engineering, a CAS in Mathematics from Cambridge
University, and doctorate in Engineering Physics at the University of
Virginia, where he was subsequently Research Assistant Professor
of Engineering Physics and Applied Mathematics. Professor
Holloway joined the faculty of U-M as an Assistant Professor for
Nuclear Engineering and Radiological Sciences in January 1990.
Subsequently promoted to Associate then full Professor, in 2007, he
was named an Arthur F. Thurnau Professor in recognition of
outstanding contributions to undergraduate education. Later that
year, he became associate dean for undergraduate education for the
College of Engineering.
As Vice Provost for Global and Engaged Education, Professor
Holloway is focused on the ways in which the U-M engages the
world through both scholarship and education. He is interested in
developing and assessing the impact of a global perspective in U-M
scholarship, and in facilitating the development of a broad set of
platforms for experiential learning accessible to all students at the UM. Professor Holloway has lived in Thailand and England, and has
worked and taught in Germany and Ghana. He has managed the UM relationship with the UM-SJTU Joint Institute in Shanghai since
2007.
Amy HUANG, 黄岩, MD, MHSA
Director for China Programs
Global REACH
Adjunct Clinical Assistant Professor
Cardiovascular Medicine
Department of Internal Medicine
University of Michigan Medical School
Amy Huang, MD, MHSA, MS, is the Director for the China Programs
at the University of Michigan Medical School. She serves as the
Program Director for the Peking University Health Science Center –
University of Michigan Medical School Joint Institute. Dr. Huang
obtained her MD degree from the Harbin Medical University and
completed her post-graduate training (MS) in Cardiology at the
Peking University Health Science Center. She then went to the
University of Michigan for her post-doctoral training in cardiovascular
biology. Dr. Huang furthered her academic training at University of
Michigan School of Public Health and obtained her Master degree in
Healthcare Service Administration. After completion of the
Administrative Fellowship with the University of Michigan Health
System, she joined the UMMS Dean’s office to establish and
manage the China platform. Dr. Huang’s research interests include
healthcare management and international collaboration.
yanhuang@umich.edu
O: 734.763.6461
C: 734.277.4076
Steven HUANG, MD
Assistant Professor, Department of Internal
Medicine
Division of Pulmonary and Critical Care
University of Michigan Medical School
stehuang@umich.edu
O: 734.963.9077
C: 734.277.7249
Dr. Huang is an Assistant Professor in the Department of Internal
Medicine, Division of Pulmonary and Critical Care Medicine at the
University of Michigan Medical School. His research interests are in
investigating how epigenetic mechanisms in different cell types in
the lung contribute to pulmonary diseases such as pulmonary
fibrosis, lung injury and repair, and asthma. He did his medical
school and internal medicine training at Northwestern University in
Chicago, IL before doing a fellowship in Pulmonary and Critical Care
at the University of Michigan. He has been a faculty member at the
University of Michigan for 8 years. He runs a basic science
laboratory and is supported by several NIH and Foundation grants.
Raymond HUTCHINSON, MD, MS
Associate Dean for Regulatory Affairs
Professor of Pediatrics and Communicable
Diseases
University of Michigan Medical School
rhutchin@med.umich.edu
O: 734.647.1576
C: 734.646.5328
Wenju JU,
, PhD, MS
Associate Research Scientist
Department of Internal Medicine
University of Michigan Medical School
wenjunj@umich.edu
O: 734.615.5757
C: 646.322.5590
Ray Hutchinson, MS, MD, Professor, Department of Pediatrics and
Communicable Diseases and Associate Dean for Regulatory Affairs
at the University of Michigan Medical School, is a graduate of
Boston College, Dartmouth Medical School, and Harvard Medical
School. He also holds a master’s degree from the University of
Michigan in clinical research design and statistical analysis. In his
role in the Dean’s Office, he oversees the medical institutional
review board chairs and boards (IRBMED), manages conflict of
interest (COI) for the Medical School, serves on the Institutional COI
Committee, assists in the resolution of faculty disputes in the
research arena, and works with the Office of the Vice President for
Research in resolving faculty research noncompliance and
misconduct. He serves on a number of University and national
committees dealing with research oversight and regulatory matters.
In the clinical realm, Dr. Hutchinson is a member of the Division of
Hematology-Oncology in the Department of Pediatrics and
Communicable Diseases, caring for children with cancer and blood
disorders. His research interests lie in the areas of the diagnosis and
management of acute lymphoblastic leukemia and Hodgkin
lymphoma and in discerning research subject understanding of the
clinical research process.
Dr. Wenjun Ju's research career has centered on which, how and
why patients with chronic kidney disease (CKD) progress to endstage renal disease (ESRD) requiring renal replacement therapy.
These three questions represent three current major unknowns in
the kidney field, and urgently need to be addressed to improve
patient care and reduce the national financial burden caused by
ESRD. Her work uses animal models and human subjects to
identify, discover and develop invasive (tissue) and non-invasive
(urine) biomarkers, with the hope of identifying novel and accurate
biomarkers. She uses statistical approaches to analyze clinical data
of patients from local, national and international study cohorts to
help assess what factors lead to CKD progression. In addition, Dr.
Ju also dedicates the majority of her research efforts to
understanding the underlying mechanisms of CKD progression and
to find targets of treatment.
Dr. Kao is received his MD degree from University of Southern
California School of Medicine in 1996 and completed his Internal
Medicine Residency at UC Davis Medical Center in California. He
completed a combined clinical/basic research GI Fellowship at the
University of Michigan.
His research interest was focused on understanding the mechanism
of GI immune homeostasis and was elected into the honorary
society of the American Society of Clinical Investigation (ASCI). As
an active National Institute of Health investigator, his current
research focuses on the role of gut microbiota in diseases of the GI
tract.
John KAO, 高永忠, MD
Associate Professor of Internal Medicine
Division of Gastroenterology
Associate Director of Research,
GI Fellowship Training Program
University of Michigan Medical School
jykao@med.umich.edu
O: 734.647.2964
C: 734.474.0631
Joseph C. KOLARS, 约瑟夫, MD
Senior Associate Dean for Education and
Global Initiatives
Josiah Macy, Jr., Professor of Health
Professions Education
University of Michigan Medical School
jckolars@umich.edu
O: 734.615.5552
C: 734.223.0876
Dr. Kao is also passionate about resident and fellow research
training and currently serves as the Associate Director of Research
for the GI Fellowship Training Program at the University of Michigan
overseeing the research progress of 21 GI/hepatology fellows in the
program. He is an associate editor of Gastroenterology and serves
on the editorial board with a special focus on basic immune
mechanisms of intestinal inflammation and homeostasis. He also
participates as a grant reviewer for National Institute of Health and
Department of Defense as well as several international grant
programs. Dr. Kao is also a practicing gastroenterologist with clinical
interests including H. pylori, IBD, Celiac disease, and C. difficile
colitis. He has established several clinical protocols at University of
Michigan Health System including management of refractory H.
pylori infection and the use of fecal microbiota transplantation for
recurrent C. difficile colitis.
Dr. Kolars obtained his MD degree in 1982 from the University of
Minnesota Medical School, pursued internal medicine training in
Minneapolis, and completed his post-graduate training
gastroenterology at the University of Michigan in 1989. After serving
as Associate Chair for Medicine and Residency Program Director,
Dr. Kolars left the University of Michigan to establish a western
based health care system in China in conjunction with Shanghai
Second Medical University. He lived with his family in Shanghai for
three years. In 1999, he joined the faculty at Mayo Clinic in
Rochester, Minnesota and served as internal medicine residency
program director for 5 years. In June of 2009, he moved to the
University of Michigan where he oversees the Associate Deans
responsible for the education programs as well as global health
initiatives for the medical school. Between 2007-2011, he worked
closely with the Bill and Melinda Gates Foundation to partner
medical schools in the U.S. with those in sub-Saharan Africa. He
currently serves as co-director for the University of Michigan Medical
School – Peking University Health Science Center Joint Institute for
Clinical and Translational Research. Current interests in medical
education focus on innovations and the transformation of learning
systems to more explicitly align with better health.
Matthias KRETZLER, MD
Warner-Lambert Parke-Davis
Professor of Internal Medicine and
Nephrology and Computational Medicine
and Bioinformatics
University of Michigan Medical School
kretzler@umich.edu
O: 734.615.5757
C: 734.323.6518
Steven L. KUNKEL, PhD
Senior Associate Dean for Research and
Endowed Professor in Pathology Research
University of Michigan Medical School
slkunkel@umich.edu
O: 734.764.3611
C: 734.358.0059
Dr. Kretzler is the Warner-Lambert/Parke-Davis Professor of Internal
Medicine/Nephrology and Computational Medicine and
Bioinformatics. The overarching goal of his research is to define
chronic organ dysfunction in mechanistic terms and use this
knowledge for targeted therapeutic interventions. To reach this goal
he has developed a translational research pipeline centered on
integrated systems biology analysis of renal disease. He leads the
U54 Nephrotic Syndrome Research Network (Neptune) in the Rare
Disease Clinical Research Network II, the Coordinating center of the
CureGN research network, is the Director of the Applied Systems
Biology Core, principle investigator in the R24 “Integrated Systems
Biology Approach to Diabetic Microvascular Complications” and in
the NIH Acceleration of Medicine (AMP) program in autoimmunity.
He has 20 years of experience in integration of bioinformatics,
molecular and clinical approaches in more than 210 papers and
holds patents for diagnostic and therapeutics of chronic renal
disease. He has a track record on interdisciplinary data integration of
large scale data sets in international multi-disciplinary research
networks in the US, Europe, China and sub-Saharan Africa. These
studies enable precision medicine across the genotype-phenotype
continuum using carefully monitored environmental exposures,
genetic predispositions, epigenetic markers, transcriptional
networks, proteomic profiles, metabolic fingerprints, digital
histological biopsy archive and prospective clinical disease
characterization. The molecular mechanisms identified have result in
new disease predictors and the first successful phase II trial of a
novel therapeutic modality in diabetic kidney disease in two
decades.
Dr. Kunkel’s areas of research have centered on assessing
molecular mechanisms of lung inflammation by investigating
cytokine directed cell-to-cell communication circuits. A significant
amount of this work helped to launch and define the field of
chemokine biology. In addition, he has been involved in assessing
epigenetic regulation of immune cell phenotypes that dictate the
expression pattern of inflammatory mediators. His studies in
cytokine and chemokine biology are internationally recognized and
have provided a more clear understanding of how these proteins are
regulated and participate in the initiation, maintenance, and
resolution of acute and chronic lung disease. He has co-authored
over 600 peer reviewed manuscripts, has been granted 14 United
States patents, an H-Index of greater than 100, presented over 150
lectures as a visiting professor/lecturer in the past 10 years, and
maintained continuous funding of major National Institute of Health
grants for a number of years.
Jun LI,
, PhD
Associate Professor of Human Genetics
and Department of Computational
Medicine and Bioinformatics
Associate Chair for Research, Department
of Computational Medicine and
Bioinformatics
University of Michigan Medical School
junzli@med.umich.edu
O: 734.615.5754
C: 650.302.7554
Dr. Li is Associate Professor of Human Genetics and Research
Associate Professor of Computational Biology and Bioinformatics at
the University of Michigan. He is also a faculty member in the
Center for Statistical Genetics, Cellular and Molecular Biology
Program, Comprehensive Cancer Center and the Depression
Center. Dr. Li's background includes a BSc in physics (Beijing
University), PhD in biophysics/electrophysiology (California Institute
of Technology), and postdoctoral training in human genetics
(Stanford). After postdoctoral training he was a Senior Scientist at
the Stanford Human Genome Center, and worked in experimental
genomics, bioinformatics, statistical genetics, and data integration
across 'omics datasets. His expertise is to apply quantitative, datadriven approaches to study genome evolution and complex human
diseases, including psychiatric disorders and cancer. He worked on
genome-wide association studies of bipolar disorder, and is the
recipient of the 2011 Johnson & Johnson Rising Star Translational
Research Award for an exome sequencing-based study of bipolar
disorder. His group has been active in sequencing-based gene
discovery: he is Co-PI on two NIH funded projects involving exome
sequencing for ataxia and thrombosis.
In other collaborations his group is also working on human
population genetics, and cancer genome evolution as revealed by
intratumoral heterogeneity, including a collaboration to study
esophageal cancer in Anyang, China. He is PI of a new NIH-funded
QTL mapping study in a rat model of metabolic health and aging.
He is recipient of the 2014 Dean's Basic Science Research Award at
the University of Michigan Medical School.
Yi Li is a Professor of Biostatistics and Director of the University of
Michigan Kidney Epidemiology and Cost Center (KECC). He had
been a faculty member in the Harvard School of Public Health for 12
years before joining Michigan in 2011. He has made many important
contributions to the research of cancer and genomic studies and
published the results in many top statistical journals, such as JASA,
JRSSB, Biometrika, and Biometrics.
Yi LI, PhD
Professor, Biostatistics
Director of Kidney Epidemiology and Cost
Center
School of Public Health
University of Michigan
yili@umich.edu
O: 734.763.6611
C: 781.467.9910
Dr. Li has been working with Drs. Wei (Duke genomic researcher
and collaborator Zhu (UM colleague and co-investigator on R01/
R21 cancer grants), Zhao (former Harvard student), He (former UM
post-doctoral fellow), Li (current UM postdoctoral fellow) and Lee
(MD Anderson collaborator) on a variety of high dimensional and big
biomedical projects. His statistical expertise encompasses largescale data analysis, feature screening, survival analysis, risk
assessment, score development and machine learning.
Andy Lin works as a bioinformatics programmer for the Molecular
and Behavioral Neuroscience Institute, which involves developing
and implementing solutions for the collection and management of
clinical research data. His efforts for the Joint Institute support
electronic data capture systems at both the University of Michigan
and Peking University. He is working with the Peking University
Clinical Research Institute to standardize systems for study data
collection, as well as preparing web-based software solutions for
research sample tracking.
Andrew William LIN, BS
System Programmer / Analyst
Molecular and Behavioral Neuroscience
Institute
University of Michigan Medical School
andylin@umich.edu
O: 734.764.7504
C: 734.276.1419
Anna Suk Fong LOK,
, MD
Professor of Internal Medicine
Alice Lohrman Andrews Research
Professor in Hepatology
Director of Clinical Hepatology
Associate Chair for Clinical Research
University of Michigan Medical School
aslok@umich.edu
O: 734.936.7511
C: 734.476.8443
Dr. Lok’s research interest is focused on natural course and
treatment of chronic hepatitis B and C, risk factors for disease
progression, and prevention of hepatocellular carcinoma. Dr. Lok
has more than 30 years’ experience in clinical and translational
research on hepatitis B and C. During this time, she contributed
original data on the characterization of the different phases of
chronic hepatitis B virus (HBV) infection, contribution of HBV
genotypes and molecular variants on disease progression, incidence
and risk factors for HBV reactivation, and responses to HBV
treatment and optimal treatment strategies. She has co-authored 4
editions of the AASLD Guidelines on HBV (2001-2009). Dr. Lok also
contributed original data on natural history of chronic HCV infection,
incidence and predictive factors associated with HCV-related HCC
development, and treatment strategies for hepatitis C, as well as
biomarkers for early diagnosis of HCC. Additionally she completed
many studies on non-invasive assessment of liver fibrosis (inventor
of APRI and Lok index).
Melissa Mccotter is the Administrative Assistant to Dr. Eugene
Chen, the co-leader of JI cardiovascular program. Melissa has
provided over 4 years of administrative support in the health care
and education arenas. Melissa also studied Medical Assisting at
Ross Medical Education Center and completed in 2009 as a Medical
Assistant.
Melissa Anne MCCOTTER
Administrative Assistant
University of Michigan Medical School
mmccotte@umich.edu
O: 734.647.5742
C: 517.404.3697
Dr. Medlin’s primary focus is on clinical informatics applied to both
the research and operational aspects of critical care and emergency
medicine. His particular skill set involves both capturing and
extracting data from clinical data systems. He is also interested in
creating clinical decision tools that operate with minimal intrusion at
the point of care.
Richard P. MEDLIN, Jr., MD, MSIS
Assistant Professor
Chief Medical Information Officer
Department of Emergency Medicine
University of Michigan Medical School
medlin@umich.edu
O: 734.615.2765
C: 919.699.6690
Dr. Meng is a vice leader for the Biomedical Informatics Core for the
Joint Institute at the University of Michigan.
His main research interests are in high throughput biomedical data
analysis and literature mining. Dr. Meng’s group is helping the
selection, development, and implementation of data management
and analysis solutions for the Joint Institute projects.
Fan MENG, 孟凡, PhD
Research Associate Professor, Psychiatry
Research Associate Professor
Molecular and Behavioral Neuroscience
Institute
University of Michigan Medical School
mengf@umich.edu
O: 734.615.7099
C: 734.353.2716
Dr. Neumar is Professor and Chair of Emergency Medicine at the
University of Michigan Medical Health System. He has over 20
years’ experience in the field of cardiac arrest resuscitation, with
international recognition as an expert in the pathophysiology and
treatment of post-cardiac arrest syndrome. His basic science
research has been focused on mechanisms of neuronal injury after
cardiac arrest as well as therapeutic strategies to improve neurologic
outcomes including therapeutic hypothermia. His clinical research
has focused on optimizing post-cardiac arrest care.
Robert W. NEUMAR, MD, PhD
Professor and Chair
Department of Emergency Medicine
University of Michigan Medical School
neumar@umich.edu
O: 734.936.6020
C: 734.756.1572
Dr. Neumar has recognized the potential to improve patient
outcomes by bringing state-of-the-art critical care capabilities into
the emergency department. He was the driving force for creation of
the Emergency Critical Care Center (EC3) at the UMHS University
Hospital. His vision is that the EC3 will not only improve patient
care, but also serve as a clinical research laboratory for first-inhuman studies of novel diagnostic, monitoring and treatment
modalities that will improve outcomes of the critically ill and injured.
Dr. Neumar is working with PUHSC collaborators to study and
optimize the delivery oif critical care in the ED setting.
Dr. Owyang’s research interests focus on neurohormonal control of
digestive functions including pancreatic endocrine and exocrine
secretion, GI motility and eating behavior. His work supports the
Pavlovian concept that the nervous system is the major regulator of
pancreatic secretion and provides the basis for understanding the
role of vagal sensory pathways in gastrointestinal disorders in
diabetes.
Chung OWYANG,
, MD
Professor of Internal Medicine
H. Marvin Pollard Collegiate Professor
Division Chief, Gastroenterology
Director, Digestive Health Center"
University of Michigan Medical School
cowyang@umich.edu
O: 734.936.4785
C: 734.660.0016
Dr. Owyang has a long standing interest in the physiology and the
pathophysiology of gastrointestinal motility. He demonstrated that in
humans, somatostatin is a potent agent to initiate intestinal migrating
motor complexes and thus can be effective in treating bowel
bacterial overgrowth in patients with chronic intestinal pseudoobstruction. In other studies, Dr. Owyang demonstrated that acute
fluctuations in serum glucose levels can impair gastric motor
function; specifically that hyperglycemia stimulates vagal pathways
that act on intragastric nitric oxide-containing neurons to induce
gastric relaxation, thus explaining the wide day to day fluctuations in
gastric emptying rates and symptoms of nausea and vomiting in
patients with diabetic gastroparesis who have stable gastric
neuropathies. He further observed that acute hyperglycemia may
cause gastric dysrhythmias due to an increased production of
prostaglandin in the stomach wall and upregulation of dopamine 2
receptors in the gastric pacemaker cells.
Dr. Owyang and his colleagues have begun to investigate the
mechanism governing nutrient sensing and peptide secretion by
enteroendocrine cells including novel taste-like pathways. These
studies may provide promising targets for new strategies to combat
obesity and diabetes.
Subramaniam PENNATHUR, MBBS, MD
Associate Professor and Director
Physician Scientist Training Program
Department of Internal Medicine
University of Michigan Medical School
spennath@umich.edu
O: 734.764.3269
C: 314.724.0592
The central theme of Dr. Pennathur’s research has focused on the
applications of biological mass spectrometry in disease
pathogenesis. A major focus of the lab has been to define the role of
oxidative stress on disease pathogenesis and complications. He
utilized mass spectrometry to identify key protein and metabolite
alterations in disease states and tested the hypothesis whether
these alterations predict complications in animal models and
humans. His strategy has been to develop analytical techniques in
animal models and validate these markers in humans and then
interrogate the animal model for biological pathway relevance.
Recent extension of this work has included targeted as well as
unbiased metabolomic and proteomic profiling.
Dr. Pennathur’s laboratory has extensive expertise in HDL biology,
functional analysis and study of dysfunctional oxidized HDL in
atherosclerosis. His laboratory also focuses on diabetic
complications including diabetic nephropathy and renal disease
progression. He serves as the co-lead for the “Dysfunctional HDL”
project of the JI.
Dr. Pinsky graduated with top honors from both the University of
Toledo and the Ohio State University College of Medicine, after
which he moved to New York to complete residency training at
Mount Sinai Hospital and cardiology and nuclear cardiology
fellowships at Columbia Presbyterian Medical Center. After
completing research training in heart failure and vascular biology, he
joined the faculty of Columbia University where he began his own
research laboratory and led the cardiology research training program
until his recruitment to the University of Michigan in 2003.
David J. PINSKY, MD
J. Griswold Ruth MD and Marjery Hopkins
Ruth Professor of Internal Medicine
Professor, Molecular & Integrative
Physiology
Founding Scholar, Taubman Medical
Research Institute
Chief, Cardiovascular Medicine
Director, Samuel & Jean Frankel
Cardiovascular Center
University of Michigan Medical School
pinsky@umich.edu
O: 734.936.3500
C: 734.255.3502
Renee W. PINSKY, MD
Associate Professor of Radiology
University of Michigan Medical School
rpinsky@umich.edu
O: 734.936.3500
C: 734.255.3503
Dr. Pinsky is an inventor on over a dozen patents, is author of over
200 scientific papers and book chapters, and leads an active
laboratory focused on understanding how natural blood vessel
defense mechanisms may be amplified to protect in conditions such
as stroke, heart attack, or organ transplantation. This work has led
him to focus on the role of protective enzymes and biological gases
such as nitric oxide and carbon monoxide which are made by blood
vessel wall cells, which defend against blood flow interruption and
inflammatory damage. He is an elected member of honorary
scientific societies including the American Society of Clinical
Investigation, the American Association of Physicians, and the
Association of University Cardiologists. He has served on and
chaired numerous national peer-review and strategy panels for the
American Heart Association, the Department of Defense, and the
National Institutes of Health, and is a popular lecturer world-wide.
Most recently, he was selected as a Senior Scholar of the Taubman
Medical Research Institute at the University of Michigan, and CoDirector of the UM-Israel Partnership for Research.
Dr. Pinsky is an Associate Professor of Radiology at The University
of Michigan Health System, specializing in breast imaging. She is an
expert at clinical breast imaging, and has been involved in both
clinical and basic research. Her areas of expertise include breast
density and related breast cancer risk, early diagnosis of breast
cancer and ductal carcinoma in situ (DCIS), and she has published
multiple papers in the area. She has represented the Michigan
Radiological Society in the Michigan Senate subcommittee session
on breast density notification legislation, contributing to
recommendations which were incorporated into the new Breast
Density Patient Notification law in Michigan. She is the content
expert and creator of a state-sponsored online continuing medical
education course and website to educate clinicians about breast
density and breast cancer screening guidelines. Dr. Pinsky is the
Chair of the committee which created the revised 2014 Michigan
Cancer Consortium Guidelines on Breast Cancer Screening, a
document which is available for all healthcare providers and patients
of Michigan on the government website. At a national level, she has
served as a board examiner for the American Board of Radiology
and currently serves on the ABR test creation committee. She
directs the University of Michigan medical student breast imaging
elective, and is the Director of the Women's Imaging sub specialty
rotation.
Tania PIOTROWSKI, MHSA
Administrative Director, Global REACH
University of Michigan Medical School
Tania Piotrowski, MHSA is the Administrative Director of Global
REACH, the University of Michigan Medical School’s unit for
developing and promoting global health research, education, and
collaborative initiatives. In this role, she works with Senior Associate
Dean Kolars to provide leadership for Global REACH in terms of
implementation of new projects and strategic planning for the future.
She works with program staff to manage day-to-day operations and
to develop coordinated approaches to launching and managing
Global REACH initiatives. Tania completed a Bachelor’s degree in
Biology at Wayne State University, and then later earned a Master of
Healthcare Administration at the University of Michigan School of
Public Health. She brings to this position 20 years of experience at
the University of Michigan in various roles involving research
administration and program management.
taniag@umich.edu
O: 734.763.7399
C: 734.474.0154
Rafael J. RAMIREZ PhD, MScA
Postdoctoral Research Fellow
Department of Internal Medicine
University of Michigan Medical School
raramire@umich.edu
O: 734.647.7194
C: 424.242.2895
Rafael J. Ramirez earned his undergraduate Bachelor’s Degree
from McGill University in Montreal, Canada with a Joint Major in
Physiology and Mathematics. He then began his scientific career as
a theoretical physiologist developing computational models of
human and canine atrial action potentials while completing his
Master’s Degree in Applied Science at Universite de Montreal under
the supervision of Drs. Stanley Nattel and Marc Courtemanche. He
obtained his PhD at the University of Toronto under Dr. Peter Backx
where his doctoral thesis work examined the role of membrane ion
channels and exchangers in cardiac excitation-contraction coupling.
Dr. Ramirez completed a Postdoctoral Scholar Fellowship at the
University of California, Los Angeles with Drs. Kalyanam Shivkumar
and Michael Laks where he developed large animal models of
myocardial infarction and investigated the involvement of cardiac
innervation in arrhythmias. Currently, he is a Postdoctoral Research
Fellow at the University of Michigan with Drs. Jose Jalife and Omer
Berenfeld where he studies mechanisms of cardiac arrhythmias and
investigates treatments for atrial fibrillation.
Richard Rogel is the President of Tomay Inc. He currently serves on
the board of AldabraII, a public SPAC, and on the board of
Viewpoints, Inc. which is a new startup. He previously founded and
served as chairman of Mobile Path Services, Inc. He was also the
founder and CEO of Preferred Provider Organization of Michigan
(PPOM). Before entering the medical management field, Mr. Rogel
worked as a management consultant for Arthur Young & Co. and as
a corporate finance associate for Burnham & Co. For eight years, he
owned and administered a multi-specialty medical center.
Richard H. ROGEL, 理查
Special Representative
University of Michigan
rrogel@umich.edu
+1.86.10940610
Andrew ROSENBERG, MD
Associate Professor of Anesthesiology,
Critical Care and Internal Medicine
Chief Medical Information Officer
Executive Director of Information and Data
Management
University of Michigan Health System
arosen@umich.edu
O: 734.936.7241
C: 734.476.1215
Mr. Rogel chaired the recent Michigan Difference Campaign that
raised USD$3.2 billion for the University of Michigan. Mr. Rogel has
been a dedicated alumnus of U-M, working as a volunteer for its
betterment. He served as president of the board of directors of the
Alumni Association and serves on several advisory groups at U-M
including the U-M School of Social Work, the Ross School of
Business, the Athletic Department and is part of a team that advises
President Mark Schlissel. He and his wife, Susan, have provided
scholarship support to hundreds of students from around the world,
making it possible for them to attend U-M. Mr. Rogel graduated as
valedictorian form the Ross School of Business and was honored
with a doctorate of laws in 2009.
Dr. Rosenberg, is the inaugural Chief Medical Information Officer for
the University of Michigan Health System. He is also the Executive
Director of Information and Data Management where he oversees
reporting, data warehousing, enterprise document management and
HIE services for the UM hospitals and health centers. Prior to these
positions, he was Director of Inpatient Information Systems at
UMHS. At that time, Dr Rosenberg was also the Chief of the Critical
Care Division in the Department of Anesthesiology, Program
Director for the Critical Care Fellowship, and the Director of the
Cardiovascular Center Intensive Care Unit. He is a tenured
Associate Professor of Anesthesiology Critical Care, & Internal
Medicine. He attended the Johns Hopkins Medical School where he
subsequently completed a residency in Internal Medicine. He then
pursued a multi-disciplinary critical care fellowship at the George
Washington University where he studied with the founders of the
APACHE ICU data and outcome systems. Following this, Dr.
Rosenberg was a Robert Wood Johnson Clinical Scholar at the
University of Michigan focusing on health-informatics, policy and
health services research. Dr Rosenberg then completed a full
anesthesiology residency there as well.
Andrew’s recent work in informatics has been in the areas of
designing and implementing enterprise analytics programs for
academic medical centers and integrating large scale enterprise
clinical electronic information systems to health system research IT
capabilities. His particular expertise includes initiating and maturing
a variety of governance organizations and implementation strategies
to successfully accomplish these socio-technical projects to advance
learning health organizations.
Dr. Standiford is a Professor of Medicine and Chief of the Division of
Pulmonary and Critical Care Medicine at the University of Michigan.
Dr. Standiford currently serves as the Program Director of the
NIH/NHLBI T32 Multidisciplinary Training Program in Lung
Diseases.
Theodore J. STANDIFORD, MD
Professor and Chief, Division of Pulmonary
and Critical Care Medicine
University of Michigan Medical School
tstandif@med.umich.edu
O: 734.936.5010
C: 734.546.5711
Dr. Standiford’s research focuses on exploring the role of specific
cells, cytokines, antimicrobial peptides and pathogen recognition
receptors in the generation of protective innate immune responses
of the lung. The epigenetic regulation of innate immunity in sepsis
and acute lung injury is an active area of both animal and human
based translational research. In human trials, Dr. Standiford has
investigated mechanisms of lung injury in ARDS and the effect of
growth factor administration on outcome in ARDS patients and in
patients at risk for the development of ARDS. Specialized areas of
clinical interest include sepsis, acute lung injury, communityacquired and nosocomial pneumonia, and tuberculosis.
Dr. Standiford has served as a permanent member of the NIH Lung
Biology and Pathology (LBPA) and the Lung Cell and Molecular
Immunology (LCMI) Study Sections. He served as a member of the
American Lung Association Research Fellowship and Career
Investigator Award Committee from 2000-2004, and Chair of this
committee from 2004-2009. He is an elected member of the
American Society for Clinical Investigation (ASCI) and the
Association of American Physicians (AAP). Dr. Standiford serves as
an external consultant for several NIH T32 training programs and an
NIH K24 patient-oriented research training program. He has
mentored >25 postgraduate research trainees and visiting
professors, including primary mentor for 7 career development
awards and co-mentor for 2 additional CDAs.
Dr. Stringer is a Professor of Clinical and Translational Pharmacy
and Director of the Nuclear Magnetic Resonance (NMR)
Metabolomics Laboratory at the University of Michigan College of
Pharmacy. She was a faculty member at the University of Colorado
School of Pharmacy before joining the faculty of the University of
Michigan College of Pharmacy in 2007. She received her PharmD
degree from the University of Michigan, completed a clinical
residency at the University of Illinois, Chicago and a post-doctoral
fellowship at the State University of New York at Buffalo.
Kathleen STRINGER, PharmD
Professor of Clinical and Translational
Pharmacy
Director, the NMR Metabolomics
Laboratory
College of Pharmacy
University of Michigan
stringek@umich.edu
O: 734.647.4775
C: 303.949.9064
Dr. Stringer’s translational research program utilizes experimental
and clinical models to tackle therapeutic problems associated with
inflammatory pulmonary diseases including chronic obstructive
pulmonary disease and critical illnesses like sepsis. She is
pioneering new techniques in metabolomics, in particular, methods
that employ NMR. She has incorporated the use of this science in
her work which is supported by the National Institutes of Health
(NIH). Dr. Stringer is a member of the American Thoracic Society
and serves as a mentor on the Department of Pulmonary and
Critical Care Medicine’s NIH-funded T32 Multidisciplinary Training
Program in Lung Disease
Dr. Su graduated from Yale University with a Bachelor of Science in
Biology and from the University of Chicago, Pritzer School of
Medicine with a Doctorate of Medicine. In addition to her academic
responsibilities, she is also the Associate Chief of Medicine,
Subspecialty Care and Access and the Chief of Gastroenterology at
the VA Ann Arbor Healthcare System, an affiliate of the University of
Michigan. Dr. Su also is an associate director for the Morphomics
Analysis Group at the University of Michigan.
Grace SU, MD, FAASLD, AGAF
Professor of Medicine and Surgery
Associate Chief of Medicine
Chief of Gastroenterology
VA Ann Arbor Healthcare System
University of Michigan Medical School
gsu@umich.edu
O: 734.764.7841
C: 734.834.2344
Dr. Su has had a long standing research interest in developing noninvasive methods of assessing liver fibrosis and as well as
understanding the pathophysiology of liver injury. For the past 6
years, she has been developing methods of quantitative image
analysis which has now evolved into analytic morphomics, an
innovative high-throughput, highly automated, anatomically indexed
methodology for assessing body composition and organ
measurements from the data files of CT scans. By linking the
morphological data to clinical outcomes, she has developed highly
accurate non-invasive methods for the diagnosis and prognosis of
liver disease. As the director of the Ann Arbor SCAN-ECHO
program, she has been an active participant of this transformational
initiative which leverages technology to improve liver subspecialty
care delivery within the VA healthcare system, particularly to
underserved and rural areas.
Ms. Tuck is a Clinical Research Project Manager in the GI/Cancer
Prevention Group at the University of Michigan. She has over 11
years of experience managing clinical trials, primarily investigatorinitiated studies. She has considerable experience in collecting,
annotating, and managing biologic specimens for biomarker
research. Prior to that, she was part of the UM IRBMed senior staff.
She has a B.A. in Biology from Albion College and a MS degree in
Biology from the University of Michigan.
Melissa K. TUCK, MS
Clinical Research Project Manager
Department of Internal Medicine
University of Michigan Medical School
mtuck@umich.edu
O: 734.763.1141
C: 734.358.0587
Thomas D. WANG, 王敦硕, PhD, MD
Associate Professor of Medicine
Biomedical Engineering, and Mechanical
Engineering
H. Marvin Pollard Collegiate Professor of
Endoscopy Research
University of Michigan Medical School
thomaswa@umich.edu
O: 734.936.1228
C: 734.358.4205
Thomas Wang is an Associate Professor in the Departments of
Medicine and Biomedical Engineering, and Mechanical Engineering
and the H. Marvin Pollard Collegiate Professor of Endoscopy
Research at the University of Michigan. He also serves as the
Principal Investigator of the NIH-funded Michigan Barrett's
Esophagus Translational Research Network (BETRNet). He is a
board certified gastroenterologist with over 25 years of experience in
developing novel optical imaging instruments and molecular probes.
Dr. Wang has pioneered the development of wide area fluorescence
imaging, the dual axes confocal endomicroscope, and clinical use of
fluorescent-labeled peptides for early detection of cancer in the
digestive tract. In addition, he is experienced at validating novel
imaging platforms, and applies his broad training to significantly
accelerate the bench to bedside process.
Dr. Wang attended Harvard Medical School where he received his
MD in 1996. He earned a PhD in Medical Engineering and Medical
Physics at the Massachusetts Institute of Technology in 1998. Dr.
Wang has published more than 50 original peer-reviewed papers on
imaging and advanced technologies, including molecular imaging,
biomarker identification and validation, targeted imaging agents, and
early detection of cancer in the digestive tract. He also serves as the
Principal Investigator of the University of Michigan Barrett's
Esophagus Translational Research Network
(http://sitemaker.umich.edu/betrnet) and the Biomedical Engineering
Research Partnership (http://sitemaker.umich.edu/brp).
Dr. Wang is an Associate Professor and Principal Investigator at the
Department of Cardiac Surgery and the Cardiovascular Research
Center, University of Michigan. He obtained his PhD from the
Oregon health and Science University and did his postdoctoral
training at the University of California, Berkeley. He was a Principal
Investigator at Massachusetts General Hospital, Harvard Medical
School and Harvard Stem Cell Institute before he moved to Ann
Arbor.
Zhong WANG, 王忠, PhD
Associate Professor and Principal
Investigator
Department of Cardiac Surgery and
Cardiovascular Research Center
University of Michigan Medical School
zhongw@umich.edu
O: 734.763.3691
C: 510.334.7065
The Wang laboratory is focusing on two research areas. One
research interest is to dissect how epigenetic events determine stem
cell self-renewal and differentiation. In particular, we are deciphering
the molecular mechanisms guiding directed differentiation of stem
cells into desired mature cell types in heart. The other research
focus is to explore novel strategies in heart regeneration by
combining cardiac stem cells, large animal models, and tissue
engineering technologies.
Kevin R. WARD, MD
Executive Director, Michigan Center for
Integrative Research in Critical Care
Executive Director, Fast Forward Medical
Innovation
Professor, Department of Emergency
Medicine
University of Michigan Medical School
keward@umich.edu
O: 734.647.4751
C: 734.834.5707
Larysa T. WICKMAN, MD, PhD
Assistant Professor of Pediatrics,
and Communicable Diseases
University of Michigan Medical School
larysa@umich.edu
O: 734.232.5411
C: 847.387.9208
Dr. Ward is a Professor in the Department of Emergency Medicine
at the University of Michigan. He received his BS in Physiology from
Louisiana State University in Baton Rouge in 1985 and his degree in
medicine from Tulane University in New Orleans, LA in 1989. Dr.
Ward then completed a residency in Emergency Medicine at the
University of Pittsburgh followed by a Resuscitation Research
fellowship at the Ohio State University in Columbus, OH. Prior to
joining the University of Michigan in 2012, Dr. Ward was Professor
and Associate Chair of Emergency Medicine at Virginia
Commonwealth University (VCU) where he also directed the VCU
Reanimation Engineering Science Center (VCURES). Dr. Ward’s
research interests span the field of critical illness and injury including
battlefield medicine in regards to oxygen transport and resuscitation,
noninvasive monitoring, hemostasis and inflammation, and in using
computational medicine and systems biology to both model and
detect injury. His approach is to develop and leverage broad
platform technologies capable of use throughout all echelons of care
of the critically ill and injured as well as in all age groups. Dr. Ward’s
work has been funded by the NIH, Department of Defense, and
NSF. He has been continuously funded by the Department of
Defense for over 10 years in areas ranging from hemostasis to
resuscitation and monitoring.
During Dr. Wickman’s training in Pediatric Nephrology, she enjoyed
taking care of patients, but in the process became increasingly
concerned by the recognition that in many instances there is a lack
of clinical tools for proper and timely diagnosis, assessment of the
efficacy of treatment and noninvasive strategies in monitoring the
disease progression. Dr. Wickman feels that there is a big need to
incorporate advances made in the basic science to the routine
patient care. With that in mind she identified the project that allowed
her to combine fascination with the science and her desire to
improve the care of the patients with the diseases she is treating.
She is very fortunate to work with and learn from Dr. Roger Wiggins
on the development of noninvasive strategies such as urinary
mRNAs detection in patients with glomerular diseases. Dr. Wickman
has a substantial amount of the preliminary and accepted for
publication data in the development of the urinary markers for the
glomerular diseases. The combination of urine podocyte marker and
podocyte density methodology opens up the potential to define
relationships between rate of podocyte detachment, podocyte loss
from glomerular tufts, development of FSGS pathologic phenotype,
and loss of kidney function that was not previously feasible. These
studies have the potential to provide improved tools to the clinic for
preventing progression of all glomerular diseases, including in
patients with Alport syndrome. The objective of this proposed
research is to determine whether or not podocyte specific urinary
mRNA biomarker methodology can be of potential use in evaluation
of patients with Alport syndrome to understand the biology of
glomerular involvement as well as non-invasively identify and
monitor podocyte loss and response to therapy.
James O. WOOLLISCROFT, 詹姆斯, MD
Dean, Medical School
Lyle C. Roll Professor of Medicine
Professor of Internal Medicine and
Medical Education
University of Michigan Medical School
Dr. Woolliscroft serves as Dean and the Lyle C. Roll Professor of
Medicine at the University of Michigan Medical School. He has
played major roles in medical student, resident and fellow education
at the University of Michigan and nationally. He is an internationally
recognized medical education scholar. In 2004, he received the
Society of General Internal Medicine (SGIM) Career Achievement in
Medical Education Award, in 2008 the Association of American
Medical Colleges’ (AAMC) Group on Educational Affairs Merrel Flair
Award. In 2014, he received the AAMC’s Abraham Flexner Award
for Distinguished Service to Medical Education. He is an elected
member of the National Academy of Medicine (formerly the Institute
of Medicine).
woolli@umich.edu
O: 734.764.8175
C: 734.646.5769
Bo YANG, 杨波, MD, PhD
Assistant Professor of Cardiac Surgery
University of Michigan Medical School
boya@umich.edu
O: 734.647.2894
C: 734.548.5392
Bo Yang, MD, PhD joined the Department of Cardiac Surgery at the
University of Michigan July 2011 after completing his General
surgery residency at the University of Arizona and Cardiothoracic
surgery fellowship at Stanford University. His clinical interests span
the range of complex adult cardiac surgical procedures including
valve sparing aortic root replacement, aortic valve repair, mitral
valve repair and replacement, aortic dissections and aneurysms,
and coronary artery disease. His research interests currently focus
on using patient specific induced pleuripotent stem cells to model
the thoracic aortic aneurysm, and study the mechanism of aneurysm
formation in Loyes-Dietz Syndrome, bicuspid aortic valve, Marfan
syndrome.
Kai ZHENG, 郑锴, PhD
Associate Professor, School of Public
Health and Information
Director, University of Michigan Health
Informatics Program
Co-Lead, Bio-Repository and Biomedical
Informatics Core
University of Michigan
kzheng@umich.edu
O: 734.763.3058
C: 412.708.2202 / +1.86.15652930636
Kai Zheng, PhD, is jointly appointed as Associate Professor of
Health Management and Policy in the School of Public Health and
Associate Professor of Information in the School of Information at
the University of Michigan. He is the Director of the University of
Michigan’s Health Informatics Program preparing students for
careers that will harness the power of information to enhance health
and transform individual health and healthcare. He is also affiliated
with the University of Michigan’s Institute for Healthcare Policy and
Innovation, Michigan Institute for Clinical and Health Research,
Medical School Department of Computational Medicine and
Bioinformatics, and Center for Entrepreneurship. He co-directs the
Bio-Repository and Biomedical Informatics Core of the University of
Michigan Health System and Peking University Health Science
Center Joint Institute for Translational and Clinical Research. Dr. Kai
Zheng received his PhD degree in Information Systems from
Carnegie Mellon University where his dissertation won the
University’s 2007 William W. Cooper Doctoral Dissertation Award in
Management or Management Science. He is the recipient of the
2011 American Medical Informatics Association New Investigator
Award that recognizes early informatics contributions and significant
scholarly achievements on the basis of scientific merit and research
excellence.