List of Scientific production
Dr Anette Weyergang
Original publications.
1. Weyergang A, Cheung L, Rosenblum M, Mohamedali K, Peng Q,
Waltenberger J and Berg K. Photochemical internalization augments tumor
vascular cytotoxicity and specificity of VEGF121/rGel fusion toxin. Journal of
Control Release. Accepted for publication jan 2014
2. Olsen CE, Berg K, Selbo PK, Weyergang A. Circumvention of resistance to
photodynamic therapy in doxorubicin-resistant sarcoma by photochemical
internalization of gelonin. Free Radic Biol Med.2013; 65:1300-9 . Epub ahead
of print
3. Vikdal M, Weyergang A, Selbo PK, Berg K. Vascular endothelial cells as
targets for photochemical internalization (PCI).Photochem Photobiol. 2013;
89(5)1185-92
4. Weyergang, A, Selbo, PK, Berg, K, Sustained ERK inhibition by EGFR
targeting therapies is a predictive factor for synergistic cytotoxicity with PDT
as neoadjuvant therapy. Biochim Biophys Acta. Gen. Subj. 2013;
1830(3)2659-70
5. Berstad, ME, Weyergang, A, Berg, K. Photochemical internalization (PCI) of
HER2-targeted toxins: synergy is dependent on the treatment sequence.
Biochim Biophys Acta.Gen. Subj. 2012;1820(12):1849-58.
6. Selbo PK, Weyergang A, Eng MS, Bostad M, Mælandsmo GM, Høgset A,
Berg K. Strongly amphiphilic photosensitizers are not substrates of the cancer
stem cell marker ABCG2 and provides specific and efficient light-triggered
drug delivery of an EGFR-targeted cytotoxic drug, J Control Release. 2012
Apr 30;159(2):197-203.
7. Weyergang, A., Berg, K., Kaalhus, O., Peng, Q., Selbo, P.K. Photodynamic
Therapy targets the mTOR signalling network in vivo and in vitro.
Mol.Pharm. 2009 6(1):255-64
8. Weyergang, A., Kaalhus, O., Berg, K. Photodynamic targeting of EGFR does
not predict the treatment outcome in combination with the EGFR tyrosine
kinase inhibitor Tyrphostin AG1478. Photochem. Photobiol Sci, 2008,
7(9):1032-40
9. Weyergang, A., Kaalhus, O., Berg, K. PDT with an endocytically located
photosensitizer cause a rapid activation of the MAPKs ERK, p38 and JNK
with opposing effects on cell survival. Mol. Cancer Ther., 2008, 7(6):17401750
List of Scientific production, Dr Weyergang
10. Weyergang, A., Selbo, PK., Berg, K. Y1068 phosphorylation is the most
sensitive target of disulfonated tetraphenylporphyrin-based photodynamic
therapy on epidermal growth factor receptor. Biochem. Pharmacol. 2007,
74(2):226-35
11. Yip, WL., Weyergang, A., Berg, K., Tønnesen, HH., Selbo, PK. Targeted
Delivery and Enhanced Cytotoxicity of Cetuximab-Saporin by Photochemical
Internalization in EGFR-Positive Cancer Cells. Mol. Pharm. 2007, 4(2):24151
12. Selbo, PK., Weyergang, A., Bonsted, A., Bown, SG., Berg, K. Photochemical
internalization of therapeutic macromolecular agents: a novel strategy to kill
multidrug-resistant cancer cells. J Pharmacol Exp Ther. 2006, 319(2):604-12.
13. Weyergang, A., Selbo, P.K., Berg, K. Photochemically stimulated drug
delivery increases the cytotoxicity and specificity of EGF-saporin. J Control
Release. 2006, 111(1-2):165-73
Review articles
1. Weyergang, A, Selbo, PK, Berstad, MEB, Bostad, M and Berg, K,
Photochemical internalization of tumor-targeted protein toxins, Lasers in
Surgery and Medicine,2011; 43: 721-3
2. Selbo PK, Weyergang A, Hogset A, Norum OJ, Berstad MB, Vikdal M, and
Berg K, Photochemical internalization provides time- and space-controlled
endolysosomal escape of therapeutic molecules, J Control Release. 2010 Nov
20;148(1):2-12.
3. Berg K, Weyergang A, Prasmickaite L, Bonsted A, Høgset A, Strand MT,
Wagner E, Selbo PK. Photochemical internalization (PCI): a technology for
drug delivery. Methods Mol Biol. 2010; 635:133-45
4. Norum, OJ., Selbo, PK., Weyergang, A., Giercksky, KE., Berg K.
Photochemical internalization (PCI) in cancer therapy: from bench towards
bedside medicine. J.Photochem Photobiol B. 2009 96(2):83-92
5. Berg, K., Folini, M., Prasmickaite, L., Selbo, P.K., Bonsted, A., Engesæter,
BE., Zaffaroni, N., Weyergang, A., Dietze, A., Mælandsmo, GM, Wagner, E.,
Norum, OJ., Høgset, A. Photochemical Internalization: A New Tool for Drug
Delivery. Curr. Pharm. Biotechnol., 2007, 8(6):362-72
6. Dietze, A., Selbo, PK., Prasmickaite, L., Weyergang, A., Bonsted,
A.,Engesater, B., Hogset, A., Berg, K. Photochemical internalization (PCI): a
new modality for light activation of endocytosed therapeuticals. J Environ
Pathol Toxicol Oncol. 2006; 25(1-2):521-3
7. Berg, K., Selbo, P.K., Weyergang, A., Dietze, A., Prasmickaite, L., Bonsted,
A., Engesaeter, B.O., Angell-Petersen, E., Warloe, T., Frandsen, N., Hogset,
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List of Scientific production, Dr Weyergang
A. Porphyrin-related photosensitizers for cancer imaging and therapeutic
applications. J. Microsc. 2005, 218(Pt 2):133-47.
Book Chapters
1. Berg, K., Weyergang, A., Høgset, A., Selbo, PK. The Potential of
Photochemical Internalixation (PCI )for the Cytosolic Delivery of
Nanomedicines. Weissing, V. and D`Souza (eds) Organelle-Specific
Pharmaceutical Nanotechnology, 311-322, Published by Wiley (John Wiley
and Sons Inc), 2010.
2. Berg, K., Bonsted, A., Weyergang, A., Høgset, A. Selbo, PK. Photochemical
Internalization, Hamblin, MR. And Mroz, P. (eds). Advances in Photodynamic
therapy; basic, translational , and clinical, pp 299-312, Norwood: Artech
House, Norwood MA, USA 2008
3. Berg, K., Prasmickaite, L., Selbo, P. K., Hellum, M., Bonsted, A., Engesæter,
B. Ø., Weyergang, A., and Høgset, A. Photochemical Internalization - A novel
technology for light-directed delivery of macromolecule therapy. In Ø. S.
Bruland and T. Flægstad (eds.), Targeted Cancer Therapies - An Odyssey, pp.
168-172. Tromsø: University Library of Tromsø, 2003
Other publications
1. Weyergang, A. Photochemical internalization of epidermal growth factor
receptor-targeted drugs, PhD thesis, School of Pharmacy, Faculty of
Mathematics and Natural Sciences, University of Oslo. 2009
2. Weyergang, A. Photochemical internalization of gelonin in cancer treatment;
Importance of Epidermal growth factor targeted cellular uptake of gelonin
upon treatment effect, Master thesis, School of Pharmacy, Faculty of
Mathematics and Natural Sciences, University of Oslo. 2003
Patents
1. Høgset, A., Weyergang, A., Selbo P.K. and Berg, K. Photochemical
Internalisation of kinase inhibitors, 2009. (PCT/GB2009/001618;
WO2010/01102).
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