ONLINE APPENDIX
Supplementary Table 1. Linear regression analysis of sPAP and mPAP
Overall
Rest
Low-intensity exercise
Moderate-intensity exercise
Peak-intensity exercise
r2
0.96
0.98
0.96
0.96
0.95
Linear Regression formula
mPAP = 0.54(sPAP) + 1.9
mPAP = 0.55(sPAP) + 1.4
mPAP = 0.54(sPAP) + 2.4
mPAP = 0.53(sPAP) + 2.6
mPAP = 0.54(sPAP) + 1.3
Claessen et al.
Echocardiography to evaluate PV and RV reserve
Supplementary Figure 1. Effect of right atrial pressure on the comparison of systolic
pulmonary artery pressure by echocardiography and by ExCMRip. Omission of right atrial
pressure (RAP) measurements for calculation of sPAP by echocardiography slightly
underestimated sPAP in those subjects with the highest sPAP values. When sPAP by
echocardiography was compared with systolic pulmonary artery pressure minus right atrial
pressure by ExCMRip a small but more consistent bias was seen.
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Claessen et al.
Echocardiography to evaluate PV and RV reserve
Supplemental Figure 2. Relationship between mean pulmonary artery pressure and
cardiac output derived by ExCMRip and by echocardiography. BMPR2, Bone
morphogenetic protein receptor type II; post-PE, post-pulmonary embolism; CTEPH, chronic
thromboembolic pulmonary hypertension; post-PEA, post-pulmonary endarterectomy; ExCMRip,
exercise cardiac magnetic resonance imaging combined with invasive pulmonary artery pressure
estimates.
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Claessen et al.
Echocardiography to evaluate PV and RV reserve
Supplementary Figure 3. Relationship between cardiac output and exercise intensity. The
left panel depicts the correlation coefficient with 95% confidence intervals (left panels) between
cardiac output and exercise intensity (in Watts). The right panel depicts individual cardiac output
augmentation during incremental exercise intensity in all subjects.
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