Capillary Electrophoresis
Block Diagram:
Vendors:
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Agilent Technologies
Varian Inc.
Applied Biosystems
Bio-Rad Laboratories
CVC Microtech
Hoefer Inc.
Beckman Coulter Inc.
Articles:
Capillary electrophoresis and sample injection systems integrated on a planar glass chip
D. Jed Harrison, Andreas Manz, Zhonghui Fan, Hans Luedi, and H. Michael Widmer
Analytical Chemistry199264 (17), 1926-1932
A T Woolley and R A Mathies. Ultra-high-speed DNA fragment separations using
microfabricated capillary array electrophoresis chips PNAS 1994 91 (24) 11348-11352
Functional Integration of PCR Amplification and Capillary Electrophoresis in a Microfabricated
DNA Analysis Device. Adam T. Woolley, Dean Hadley, Phoebe Landre, Andrew J. deMello,
Richard A. Mathies, and, and M. Allen Northrup. Analytical Chemistry199668 (23), 4081-4086
Common Applications:
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Can be used to identify the genotype of organisms by determining their DNA sequence
Can analyze pharmaceuticals and other basic drugs
Can characterize proteins