Curriculum Vitae 09 - Karl Skala for 3rd Ward Council

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Curriculum Vitae of

KARL DANIEL SKALA

5201 Gasconade Drive

Columbia, Missouri 65202

(573) 474-2195

E-mail: [email protected]

EDUCATION

F

ORMAL

:

University of Missouri, Columbia, MO

M. A. degree in Psychology (Experimental - 86 graduate hours) ………………….……..……1986

Massachusetts Institute of Technology, Cambridge, MA

Certification in Biomechanics of Human Movement ……………...…………………………..1984

Southern Illinois University, Carbondale, IL

B. A. degree in Psychology (Biology minor)..………………………………………...…......…1977

T

ECHNICAL

:

U. S. Marine Corps Communications & Electronics School, San Diego, CA

Graduate of Electronics & Aviation Radar Repair Program ……………………...………....…1967

PROFESSIONAL SKILLS

Administrative:

Core Director, laboratory manager, personnel supervisor, procurement, purchasing & inventory

Biomechanics:

Movement analysis system (Selspot®); kinematics

Cardiovascular:

Cardiovascular researches; Coronary stent research; Cardiac cannulation & ultrasound (swine), micro-vascular cannulation (mouse); diabetes & hypertension studies (swine & rodent)

Computer Applications:

PC® & Macintosh® platforms; Integrated office (MS Office®); Statistical & graphic analyses; Image processing (ImagePro® & Adobe Photoshop®)

Electronics:

Audio, video, test equipment utilization, maintenance & repair

Experimental Design:

Design, strategy, control, analysis, & critical evaluation; hypothesis testing

Histology:

Necropsy & perfusion; tissue preparation & dissection, frozen and paraffin sectioning & staining

Mechanical:

Mechanical drawing, design & fabrication of experimental apparatus

Neuroscience:

Brain integrity, dysfunction & recovery; Stereotaxic central cannulae preparations (primate & rodent); cortical ablation & electrolytic lesion

Supervisory:

Military, research/technical staff & student

Statistics:

Descriptive & inferential (SAS, SPSS & SigmaStat); parametric & nonparametric

Teaching

:

Teaching & tutoring; interviews, psychometrics & testing; public presentations & reports

Technical:

Writing

:

Behavioral & kinesiological measurement; physiological (EEG, EMG & EKG), radio telemetry; immunohistochemistry & radioimmunoassay; 2D & 3D image processing; bright field & confocal fluorescence microscopy

Manuscripts, proposals, research/animal care & use protocols, reports, summaries, & reviews

Curriculum Vitae of

KARL DANIEL SKALA

Page 2

PROFESSIONAL EXPERIENCE

R

ESEARCH

:

Psychopharmacology:

Southern Illinois University-Carbondale ................................................................................... 1976

Comparative models of neurological recovery;

Undergraduate Research Assistant to Dr. L. Baez

Neuropsychology of Primates:

Southern Illinois University-Carbondale ............................................................................. 1976-79

Comparative models of learning & memory;

Graduate Research Assistant to Dr. D. K. Bliss

Atomic & Molecular Physics:

University of Illinois-Chicago .............................................................................................. 1979 -80

LASER systems applications & development; optics;

Assistant Research Engineer for Dr. C. K. Rhodes

Behavioral Toxicology:

University of Missouri-Columbia ........................................................................................ 1981 -83

Behavioral assessments of exposure to methyl-mercuric chloride;

Graduate Research Assistant to Dr. D. C. Wright & Dr. V. St. Omer

Human Infant Development:

University of Missouri-Columbia ........................................................................................ 1983 -85

Infant motor development & interlimb coordination;

Graduate Research Assistant to Dr. E. Thelen

Physiological Psychology:

University of Missouri-Columbia ........................................................................................ 1984 -86

Comparative models of learning & memory; neurological recovery;

Graduate Research Assistant to Dr. D. C. Wright

Department of Neurology:

University of Missouri-Columbia School of Medicine ...............................................................1987

Researches of Myasthenia gravis;

Graduate Research Assistant to Dr. J. D. Dexter

Human Learning:

University of Missouri-Columbia ........................................................................................ 1988 -89

Brain lateralization; visual split field techniques;

Graduate Research Assistant to Dr. J. H. Mueller

Behavioral Toxicology:

Lincoln University-Jefferson City ....................................................................................... 1989 -90

Behavioral & morphological researches with the artificial sweetener, Aspartame;

Biomedical researcher for Dr. R. H. Hancock

Neuroendocrinology:

University of Missouri-Columbia School of Medicine ........................................................ 1990-92

Hypothalamic-pituitary unit researches; Atrial natriuretic peptides;

Biomedical researcher for Dr. W. K. Samson

Department of Obstetrics & Gynecology & Veterinary Biomedical Sciences:

University of Missouri-Columbia Schools of Medicine & Veterinary Medicine …………. 1992-94

Development of an in vitro model for uterine drug screening;

Biomedical researcher for Dr. S. W. Snyder

Department of Internal Medicine - Cardiology:

University of Missouri-Columbia School of Medicine ........................................................ 1994-96

Vascular Endothelium researches; Microvascular researches; Canine

Stent Research Project Coordinator/Cordis Corp.

Biomedical researcher for Dr. P. R. Myers & Dr. R. Webel

Curriculum Vitae of

KARL DANIEL SKALA

Page 3

PROFESSIONAL EXPERIENCE continued

R

ESEARCH

cont.:

Dalton Cardiovascular Research Center:

University of Missouri-Columbia Vascular Biology Laboratory ..............………............... 1996-00

Two & Three dimensional imaging; Confocal fluorescence microscopy;

Cardiovascular Surgery (swine); Swine model of Diabetes

Laboratory Manager & Senior Biomedical Researcher for Dr. M. Sturek

Dalton Cardiovascular Research Center:

University of Missouri-Columbia Cardiovascular Neurobiology Laboratory .................. 2001-2005

Laboratory Manager, Cardio-microvascular & central stereotaxic surgery;

Immunohistochemistry; Imaging; Confocal fluorescence microscopy

Animal models for Hypertension & Barorecepter Regulation (rodent)

Laboratory Manager & Senior Biomedical Researcher for Dr. M. Hay

Department of Veterinary Medicine & Biological Sciences:

University of Missouri-Columbia School of Veterinary Medicine .................................. 2005-2008

Director, Swine Hormone Research Core; Cardiovascular Metabolism Laboratory, Manager

Immunohistochemistry; Imaging; Confocal fluorescence microscopy; Autosampling

Animal models for Vascular Metabolism & Cardiovascular Regulation (swine & rodent)

Laboratory Manager & Senior Associate for Dr. L. Rubin

T

EACHING

:

Experimental Physiological Psychology:

Southern Illinois University-Carbondale ................................................................................... 1976

Neurosurgical techniques;

Undergraduate Teaching Assistant to Dr. R. Wilcox

Behavioral Sciences:

Southern Illinois University-Carbondale School of Medicine ....................…...................... 1977-78

Tutoring & course evaluation;

Graduate Teaching Assistant to Dr. D. K. Bliss

Comparative & Physiological Psychology:

University of Missouri-Columbia .............................................................................................. 1980

Lecture & course evaluation;

Graduate Teaching Assistant to Dr. D. C. Wright

Experimental Psychology:

University of Missouri-Columbia ......................................................................................... 1985-86

Lecture, demonstration, & equipment maintenance;

Graduate Teaching Assistant to Dr. R. Wright

Human Learning:

University of Missouri-Columbia ......................................................................................... 1988-89

Brain lateralization; visual split field techniques;

Graduate Teaching Assistant to Dr. J. H. Mueller

Research Group Staff Certification:

Lincoln University-Jefferson City .............................................................................................. 1989

Specialized laboratory animal procedures series: presentation & demonstration;

Guest lecturer invited by Dr. S. Meredith

PERSONAL DATA

F

AMILY

:

H

EALTH

:

V

ETERAN

:

V

OLUNTEER

:

Married with three children

Excellent

U. S. Marine Corps (Vietnam Era), Honorable Discharge (1972), Sergeant (E5)

City Councilman, Columbia MO (2007-now)

Curriculum Vitae of

KARL DANIEL SKALA

Page 4

BIBLIOGRAPHY

Modrow, H. E., Petroff, R. J.,

Skala, K. D.

, and Bliss, D. K. (1977).

Effects of amygdala lesions on state dependent learning and transfer.

Paper presented at the meeting of the Eastern Psychological Association, Boston.

Modrow, H. E.,

Skala, K. D.

, and Bliss, D. K. (1977). Effects of cortical ablations on transfer in a state dependent learning paradigm.

Bulletin of the Psychonomic Society

, 10, 255.

Skala, K. D.

, Modrow, H. E., and Bliss, D. K. (1977). Effects of small thalamic (centrum medianum) lesions on state dependent learning and transfer.

Bulletin of the Psychonomic Society

, 10, 255.

Modrow, H. E.,

Skala, K.

, and Bliss, D. K. (1978). Physiological substrates of state dependent learning.

Psychopharmacology

, 58, 8.

Modrow, H. E.,

Skala, K.

, Petroff, R., and Bliss, D. K. (1978). Physiological substrates of state dependent learning. In F. C. Colpaert and J. A. Rosecrans (Eds.),

Stimulus Properties of Drugs: Ten Years of

Progress

(pp. 415-421). Amsterdam: Elsevier/North-Holland Biomedical Press.

Skala, K. D.

, Fisher, D. M., and Thelen, E. (1984).

Kinematic analysis of infant kicking: Weight gain as a nonneurological factor in interlimb coordination.

Paper presented at the Annual Research & Creative

Activities Forum, University of Missouri, Columbia.

Skala, K. D.

(1986). Interoperative visual experience and the serial lesion effect. M. A. Thesis, University of

Missouri, Columbia.

Wright, D. C.,

Skala, K. D.

, and Peuser, K. A. ((1986). Latent inhibition from context-dependent retrieval of conflicting information.

Bulletin of the Psychonomic Society

, 24, 152-154.

Thelen, E.,

Skala, K. D.

, and Kelso, J. A. S. (1987). The dynamic nature of early coordination: Evidence from bilateral leg movements in young infants.

Developmental Psychology

, 23(2), 179-186.

Wright, D. C.,

Skala, K. D.

, and Cloud, M. D. (1987).

Does "multiple encoding" produce the serial lesion effect?

Paper presented at the meeting of the Midwestern Psychological Association, Chicago.

Skala, K. D.

, and Wright, D. C. (1987).

Multiple state training protects old memories retrieved following brain damage.

Paper presented at the Annual Research & Creative Activities Forum, University of Missouri,

Columbia.

Wright, D. C., Cloud, M. D., and

Skala, K. D.

(1988).

State dependent retrieval and the serial lesion effect.

Paper presented at the meeting of the Psychonomic Society, Chicago.

Samson, W. K.,

Skala, K. D.

, Alexander, B., and Huang, F.-L. S. (1990). Pituitary site of action of endothelin: selective inhibition of prolactin release in vitro.

Biochemical and Biophysical Research Communications

,

169(2), 737-743.

Samson, W. K.,

Skala, K.

, Huang, F.-L. S., Gluntz, S., Alexander, B., and Gomez-Sanchez, C. E. (1991). Central nervous system action of endothelin-3 to inhibit water drinking in the rat.

Brain Research

, 539, 347-351.

Samson, W. K.,

Skala, K. D.

, Alexander, B., and Huang, F.-L. S. (1991). Possible neuroendocrine actions of endothelin-3.

Endocrinology

, 128, 1465-1473.

Samson, W. K.,

Skala, K. D.

, Alexander, B., and Huang, F.-L. S. (1991). Hypothalamic endothelin: presence and effects related to fluid and electrolyte homeostasis.

Journal of Cardiovascular Pharmacology,

17(S7),

345-348.

Samson, W. K., Alexander, B. D.,

Skala, K. D.

, Huang, F.-L. S., and Fulton, R. J. (1991). Central peptidergic mechanisms controlling reproductive hormone secretion: a novel methodology reveals the role of the natriuretic peptides.

Canadian Journal of Physiology and Pharmacology,

70(5), 773-778.

Samson, W. K.,

Skala, K. D.

, and Huang, F.-L. S. (1991). CNP-22 stimulates, rather than inhibits, water drinking in the rat: evidence for a unique biological action of the c-type natriuretic peptides.

Brain Research

, 568,

285-288.

Samson, W. K.,

Skala, K. D.

, and Huang, F.-L. S. (1991). Hypothalamic endothelin: presence and site of action.

FASEB Journal

5

(5), 1147.

Samson, W. K., Alexander, B. D.,

Skala, K. D.

, Huang, F.-L. S., and Fulton, R. J. (1992). Oxytocin-ricin cytotoxin conjugate administration reveals a physiologically relevant role for oxytocin in the control of gonadotropin secretion.

Annals of the New York Academy of Sciences,

652, 411-422.

Samson, W. K.,

Skala, K. D.

, Huang, F.-L. S., Alexander, B. D., and Gomez-Sanchez, C. E. (1992). A prolactin release inhibiting activity isolated from neurointermediate lobe extracts is an endothelin-like peptide.

Regulatory Peptides

, 39(1), 103-112.

Curriculum Vitae of

KARL DANIEL SKALA

Page 5

BIBLIOGRAPHY continuation

Samson, W. K., and

Skala, K. D.

(1992). Comparison of the pituitary effects of the mammalian endothelins: vasoactive intestinal contractor (endothelin-beta, rat endothelin-2) is the most potent inhibitor of prolactin secretion.

Endocrinology

, 130(5), 2964-2970.

Huang, F. -L.,

Skala, K. D.

, Samson, W. K. (1992). Hypothalamic effects of c-type natriuretic peptide (CNP) on luteinizing hormone secretion.

Journal of Neuroendocrinology,

4(3), 325-330.

Huang, F. -L.,

Skala, K. D.

, Samson, W. K. (1992). C-type natriuretic peptide stimulates prolactin secretion by a hypothalamic site of action.

Journal of Neuroendocrinology,

4(5), 593-597.

Snyder, S. W.,

Skala, K. D.

, Adams, H. A., and Sturek, M. S. (1994). The selective effects of platelet activating factor, tumor necrosis factor and prostaglandin F

2a

Sciences

.

in vitro. Life

Dietz, N. J.,

Skala, K.

, and Sturek, M. (1996).

Localized Ca

2+

release from the sarcoplasmic reticulum of coronary smooth muscle cells resolved with video rate imaging.

Paper presented at the International Meeting of

Vascular Biology, Seattle, Washington.

Dietz, N. J.,

Skala, K.,

and Sturek, M. (1997).

Localized Ca

2+

release from the sarcoplasmic reticulum of coronary smooth muscle cells resolved with video rate imaging and laser scanning confocal microscopy.

Abstract and poster presentation for Cardiovascular Day, University of Missouri, Columbia.

Skala, K.

, Voelker, D. J., Reddy, H. K., and Sturek, M. (1997).

Three-dimensional reconstruction of intravascular ultrasound images from human coronary arteries.

Abstract and poster presentation for Cardiovascular

Day, University of Missouri, Columbia.

Skala, K.,

Dietz, N, J., and Sturek, M. (1998).

Interdisciplinary Diabetes and Cardiovascular Research.

Video poster presentation for Cardiovascular Day, University of Missouri, Columbia.

Otis, C. R., Wamhoff, B. R.,

Skala K

., and Sturek, M. (1999).

Hyperlipidemia decreases insulin sensitivity in diabetic swine.

Abstract and poster presentation for Cardiovascular Day. University of

Missouri, Columbia. Abstract and poster presentation for Cardiovascular Day, University of Missouri,

Columbia.

Otis, C. R., Wamhoff, B. R., Provencher, I., Arnsmeyer, J., Pineda,

Skala K

., and Sturek, M. (1999).

Insulin sensitivity testing in Yucatan swine

. Abstract and poster presentation for the 34 th

Annual Midwest

Regional AALAS Meeting, Mid-Missouri Branch of the American Association for Laboratory Animal

Science, Columbia, Missouri.

Pineda, J., Wamhoff, B. R., Otis, C., Provencher, I., Arnsmeyer, J.,

Skala, K.

, and Sturek, M. (1999).

Diabetic Yucatan Swine: maintenance of hyperglycemia and body weight.

Abstract and poster presentation for the 34 th

Annual Midwest Regional AALAS Meeting, Mid-Missouri Branch of the American

Association for Laboratory Animal Science, Columbia, Missouri.

Skala, K.

, Wamhoff, B. R., Otis, C., Provencher, I., Arnsmeyer, J., Pineda, and Sturek, M. (1999).

Vascular access port implantation in diabetic miniature swine: complications and outcomes.

Abstract and poster presentation for the 34 th

Annual Midwest Regional AALAS Meeting, Mid-Missouri Branch of the

American Association for Laboratory Animal Science, Columbia, Missouri.

Sturek, M., Reddy, H. K., Voelker, D. J.,

Skala, K.

, Wamhoff, B. R., Humphrey, C. D., Luis-Fuentes, V., and

Bonagura, J. (1999).

Coronary angiography and intravascular ultrasound procedures in Yucatan miniature swine

. Abstract and poster presentation for the 34 th

Annual Midwest Regional AALAS Meeting, Mid-

Missouri Branch of the American Association for Laboratory Animal Science, Columbia, Missouri.

Xue B.,

Skala, K.

, Hay M. (2003) Sex differences in baroreflex function in the development of Angiotensin IIinduced hypertension in conscious mice.

Society of Neuroscience

, 923.15.

Xue, B.,

Skala, K.

, Hay M. (2003) Gender difference in the development of Angiotensin II-induced hypertension in conscious mice.

FASEB Journal

, A1294:8253.

Xue, B.,

Skala, K.

, Jones, T.A., Hay, M. (2004) Diminished baroreflex control of heart rate responses in otoconiadeficient head tilt (

het

) mice.

Am J Physiol Heart Circ Physiol

, 287(2): H741-h747 Abstract

Xue, B., Pamidimukkala, J.,

Skala, K.

, Hay, M. (2004) Role of central estrogen receptors and androgen receptors in

Angiotensin II-induced hypertension in conscious mice.

FASEB Summer Research Conferences.

Xue, B., Pamidimukkala, J.,

Skala, K.

, Hay, M. (2004) Role of androgens and central androgen receptors in

Angiotensin II-induced hypertension in the conscious male mice. Presentation for

Iowa Physiological

Society.

Curriculum Vitae of

KARL DANIEL SKALA

Page 6

BIBLIOGRAPHY continuation

Xue, B,

Skala, K

., Pamidimukkala, J., Hay, M. (2004) Androgens modulate Angiotensin II-induced hypertension in the conscious male mice

. FASEB Journal

, A649, 4396.

Xue, B.,

Skala, K

, Pamidimukkala, J., Hay, M. (2005) Protective effect of central nitric oxide (NO) in Angiotensin

II-induced hypertension in conscious female mice.

IUPS/FASEB.

Skala, K.

, Pamidimukkala, J., Hay M. (2005) Immunohistochemical Expression of NADPH Oxidase in the Mouse

Forebrain and Brainstem

. FASEB Journal

, A835:7651.

Olmstead, A.,

Skala, K

, Dodam, J., Rubin, L. (2006) Modulation of Heart Rate Variability Using Androgen

Receptor Blocker. The Society of Phi Zeta, University of Missouri-Columbia School of Veterinary

Medicine.

ACKNOWLEDGMENTS

Kligler, D. J., Bokor, J., and Rhodes, C. K. (1980). Collisional and radiative properties of the H2 EF Eg state.

Physics Review A

,

21

, 607.

K. Skala

acknowledged for technical assistance.

Bokor, J., Zavelovich, J., and Rhodes, C. K. (1980). Isotope effect in multiphoton ultraviolet photolysis of CO.

Journal of Chemical Physics

,

72

, 965-971

. K. Skala

acknowledged for technical assistance.

Hawkins, R. T., Egger, H., Bokor, J., and Rhodes C. K. (1980). A tunable, ultrahigh spectral brightness KrF

* excimer laser source. assistance.

Applied Physics Letters

,

36

, 391-392.

K. Skala

acknowledged for technical

Buelke-Sam, J. C., Kimmel, C. A., Adams, J., Nelson, C. J., Vorhees, C. V., Wright, D. C., St. Omer, V., Korol, B.

A., Butcher, R. E., Geyer, M. A., Holson, J. F., Kutscher, C. L., and Wayner, M. J. (1985). Collaborative

Behavioral Teratology Study: Results. Neurobehavioral Toxicology and Teratology 7 (6), 591-624.

K. Skala

acknowledged for technical assistance.

Snyder, S. W., Rigby, S. L., and Adams, H. A. (1994). The role of oxytocin in

in vitro

contractile activity in rat uterine tissue.

Life Sciences

,

55

(5), 399-411

. K. Skala

acknowledged for technical assistance.

Snyder, S. W. (1994). Selective effects of platelet activating factor and prostaglandin F

2a

on pregnant rat uterine contractility

in vitro

.

American Journal of Obstetrics and Gynecology

.

K. Skala

acknowledged for technical assistance.

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