DRAFT PROPOSAL TO _________________________ FOR REVIEW BY _________________________. Background and Introduction Each year in sub-Saharan Africa an estimated 135,000 to 150,000 people die from reversible Acute Kidney Failure (AKF) caused by malaria, sepsis (infection), acute diarrheal illnesses (especially in children), and obstetrical complications. Since 2009, the Sustainable Kidney Care Foundation (SKCF) has demonstrated the effectiveness of treating reversible AKF with Peritoneal Dialysis (PD) in low technology settings. Because of the simplicity of the equipment, the proven clinical process, treating AKF with PD is possible in a growing number of developing countries. SKCF has established successful programs in the effective delivery of this treatment in remote, resource poor settings. Currently, SKCF has five active PD programs in sub-Saharan Africa with four more slated to begin in the coming year. The need for these services is great given that most of the developing countries are currently unable to provide this life sustaining service. While the programs SKCF has established have been fruitful, they lack the human resource support necessary to continue training local clinicians and establishing grass roots educational programs to inform the local communities of the availability of this vital service, educating them concerning prevention and assisting in early treatment programs. SKCF proposes establishing a training ground for Greek nephrologists, including Fellows, nurses and recent university graduates to work with SKCF programs currently underway and those soon to launch. Currently SKCF is working in consort with the three international nephrology associations in the education and training of local healthcare workers: o The International Society of Nephrology (ISN) o The International Pediatric Nephrology Association (IPNA) o And the International Society of Peritoneal Dialysis (ISPD). In this proposal, the SKCF seeks to join forces with prominent Greek nephrologists, nephrology practices and nephrology departments in Greek hospitals and universities to help identify and supply the manpower and expertise needed to expand PD programs and provide additional vital support to those programs already underway. Terms of service can be as short as three months to as long as one year with opportunities for extensions if desired. General Outline of Proposal The SKCF’s mission is”TO ESTABLISH ENDURING TREATMENT PROGRAMS WHERE NONE EXIST – FOR PATIENTS WITH SUDDEN, REVERSIBLE KIDNEY FAILURE.” We therefore propose to establish programs to treat Acute Kidney Failure using Peritoneal Dialysis in countries that currently are unable to provide this therapy. This requires training of local clinicians, providing the consumables required to effectively treat AKF, and developing outreach programs in local villages to refer AKF patients for treatment before their condition becomes untreatable, and to create AKF prevention programs, as well. Manpower Hospital Based Programs For each site selected, SKCF will recruit 1 – 2 doctors who will be committed to stay for a period of 3 months to one year to work side by side with local doctors providing support and training in nephrology and peritoneal dialysis. Additional support will be provided by senior level doctors who will be invited for stays of 1 -2 weeks expected to return every 3-4 months. Experienced dialysis nurses will also be invited to provide training to the local nurses in the methods of caring for peritoneal dialysis patients Outreach Programs Currently, many AKF patients die because there is no PD treatment available for them or because they are referred too late in the course of losing their kidney function. We propose for each PD program selected, that we will train 2-3 Greek university graduates to aggressively liaise with villages in close proximity to PD program sites for the purpose of training local health care workers in the availability of the program, helping to educate local residents to know AKF signs/symptoms, and to assist in rapid referral of patients to established treatment programs. Telemedicine Telemedicine is the use of medical information exchanged from one site to another via electronic communications to improve a patient’s clinical health status. Telemedicine includes a growing variety of applications and services using twoway video, email, smart phones, wireless tools and other forms of telecommunications technology. Examples include patient consultations via video conferencing, transmission of still images, e-health including patient portals, remote monitoring of vital signs, continuing medical education, consumer-focused wireless applications and nursing call centers, among other applications, are all considered part of telemedicine. As part of our proposal we plan to engage a Greek “telemedicine provider” (i.e. CardioExpress [http://www.cardioexpress.gr/en/htmls/company.htm], or Vodafone, Greece [http://www.vodafone.gr/portal/client/cms/viewCmsPage.action?pageId=11280&request_locale=en] – to develop basic telemedicine capabilities whereby SKCF will be able to engage in better prevention and treatment of AKF. Summary At present, research we have done indicates the unemployment rate for doctors in Greece is estimated at 25%; for young doctors just graduating from medical school the unemployment rate can be as high as 65%. Many are forced to leave Greece to find employment elsewhere or continue to become a drain on the social services system. However, because there is much need and work for them in the developing world, our proposal includes Providing a life giving therapy for indigenous people suffering from AKF Providing a creative employment opportunity And fostering improved knowledge, experience and skills for participants who will later return to Greece. We estimate the cost for each site chosen to be approximately $335,000 for the first year, as summarized in the schedule below. Currently SKCF has a long waiting list of hospitals in remote, resource poor countries anxious to establish PD programs; our only limitation is the availability of personnel and the resources necessary to support them. Estimated Budget per Site (US$) Site 1 Physician 1 (full time) Physician 2 (full time) Physician 3 (full time) Senior physician ( 4 visits) Nurse (four extended visits) Grad Student 1 Grad Student 2 Grad Student 3 Grad Student 4 Housing/Meals Telemedicine costs Health and other insurance Transportation Peritoneal dialysis consumables SKCF Staff travel and administration Total Year 1 Year 2 Year 3 Total $ 24,000 $ 24,500 $ 25,000 $ 73,500 24,000 24,500 25,000 73,500 24,500 25,000 49,500 4,000 4,500 5,000 13,500 6,000 6,200 6,500 18,700 12,000 12,250 12,500 36,750 12,000 12,250 12,500 36,750 12,250 12,500 24,750 12,500 12,500 80,000 116,000 134,000 330,000 8,000 12,000 14,000 34,000 25,000 42,500 47,000 114,500 64,500 86,000 96,750 247,250 35,000 30,000 15,000 80,000 40,000 45,000 50,000 135,000 $ 334,500 $ 452,450 $ 493,250 $ 1,280,200