Supplementary Table 1. Studies used to create a hierarchical summary of the receiver
operating characteristic model curve in obtaining the diagnostic performance of myocardial
perfusion CT alone for the evaluation of myocardial ischemia (per vessel)
Yea
Numb
Referen
Modali Sensitivi
Specifici
PP
NP
T
T
F
F
Re
r
er of
ce
ty
ty, %
V,
V,
P
N
P
N
f.
patient
standar
%
%
s
d
56
81
2
43
2
10 [39
ty, %
(vessel
s)
201
42
FFR ≤
2
(103)
0.80
201
42
FFR ≤
2
(86)
0.80
201
101
FFR ≤
3
(303)
0.80
201
97
FFR ≤
3
(81)
0.75
201
65
FFR <
3
(195)
0.80
201
32
FFR ≤
3
(96)
0.75
201
80
FFR ≤
4
(210)
0.75
CTP
74
66
8
CTP
76
84
82
79
3
2
38
7
]
10 [36
1
CTP
CTP
55
93
95
90
78
84
87
96
]
4
21
1
0
9
1
2
47
5
33 [34
]
2
7
CTP
CTP
95
83
74
88
49
75
98
92
]
3
11
4
9
4
0
2
59
8
2
88
90
77
95
[31
]
5
4
CTP
[66
[41
]
4
13
1
9
9
5
7
[67
]
CTP myocardial perfusion CT, FFR fractional flow reserve, FN false negative, FP false
positive, NPV negative predictive value, PPV positive predictive value, Ref. reference
number, TN true negative, TP true positive
Supplementary Table 2. Studies used to create a hierarchical summary of the receiver
operating characteristic model curve in obtaining the diagnostic performance of CT-derived
fractional flow reserve alone for the evaluation of myocardial ischemia (per vessel)
Yea Numb
Refere
Modal
Sensitiv
Specific
PP
NP
T
T
F
F
Re
r
er of
nce
ity
ity, %
ity, %
V,
V,
P
N
P
N
f.
patien
standar
%
%
ts
d
74
92
51
83
1
7
[5
(vesse
ls)
201 103
FFR ≤
CT-
1
0.80
derive
(159)
88
82
8
6]
d FFR
201 252
FFR ≤
CT-
2
0.80
derive
(408)
80
61
56
84
12
16
9
3
[5
1
0
6
0
7]
83
33
5
1
[3
3
2
6
3]
47
3
6
[2
d FFR
201 251
FFR ≤
CT-
3
0.80
derive
(484)
84
86
61
95
d FFR
201 53
FFR ≤
CT-
2
0.80
derive
(82)
81
94
90
89
26
3]
d FFR
201 106
FFR ≤
CT-
4
0.80
derive
(189)
88
65
65
88
70
71
3
1
[5
8
0
9]
d FFR
CT-derived FFR CT-derived fractional flow reserve, FFR fractional flow reserve, FN false
negative, FP false positive, NPV negative predictive value, PPV positive predictive value,
Ref. reference number, TN true negative, TP true positive